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Thyroid cancer - Pipeline Insight, 2021

May 2021 | 60 pages | ID: T756BACBB0EEN
DelveInsight

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DelveInsight’s, “Thyroid cancer - Pipeline Insight, 2021,” report provides comprehensive insights about 35+ companies and 35+ pipeline drugs in Thyroid cancer pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Geography Covered
  • Global coverage
Thyroid cancer Understanding

Thyroid cancer: Overview

Thyroid cancer is a disease in which malignant (cancer) cells form in the tissues of the thyroid gland. Thyroid nodules are common but usually are not cancer. There are different types of thyroid cancer. Age, gender, and being exposed to radiation can affect the risk of thyroid cancer. Medullary thyroid cancer is sometimes caused by a change in a gene that is passed from parent to child. Signs of thyroid cancer include a swelling or lump in the neck. Tests that examine the thyroid, neck, and blood are used to diagnose thyroid cancer. Certain factors affect prognosis (chance of recovery) and treatment options.

'Thyroid cancer - Pipeline Insight, 2021' report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Thyroid cancer pipeline landscape is provided which includes the disease overview and Thyroid cancer treatment guidelines. The assessment part of the report embraces, in depth Thyroid cancer commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Thyroid cancer collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Report Highlights
  • The companies and academics are working to assess challenges and seek opportunities that could influence Thyroid cancer R&D. The therapies under development are focused on novel approaches to treat/improve Thyroid cancer.
Thyroid cancer Emerging Drugs Chapters

This segment of the Thyroid cancer report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Thyroid cancer Emerging Drugs
  • Donafenib: Suzhou Zelgen Biopharmaceuticals
Donafenib, an orally administered multikinase inhibitor, is being developed by Suzhou Zelgen Biopharmaceuticals for the treatment of Late stage cancers. The product targets Raf kinase and various receptor tyrosine kinases (RTKs), with potential antineoplastic activity. Currently, it is in phase 3 of development stage for the treatment of thyroid cancer.
  • Anlotinib: Jiangsu Chia-Tai Tianqing Pharmaceutical
Anlotinib is an orally administered tyrosine kinase inhibitor that targets vascular endothelial growth factor receptor (VEGFR), fibroblast growth factor receptor (FGFR), platelet-derived growth factor receptors (PDGFR), and c-kit. Currently, it is in phase 3 of development stage for the treatment of thyroid cancer.
  • Ponatinib: Takeda
Ponatinib is an orally active, small-molecule multi-targeted tyrosine kinase inhibitor (TKI), being developed by Takeda, for the treatment of various cancer. Currently, it is in phase 2 of development stage for the treatment of thyroid cancer.
  • Nivolumab: Bristol-Myers Squibb
Nivolumab) is a human immunoglobulin G4 (IgG4) monoclonal antibody that binds to the PD-1 receptor and blocks its interaction with PD-L1 and PD-L2, releasing PD-1 pathway-mediated inhibition of the immune response, including the anti-tumor immune response. Currently, it is in phase 2 of development stage for the treatment of thyroid cancer.

Further product details are provided in the report..

Thyroid cancer: Therapeutic Assessment

This segment of the report provides insights about the different Thyroid cancer drugs segregated based on following parameters that define the scope of the report, such as:
  • Major Players in Thyroid cancer
There are approx. 35+ key companies which are developing the therapies for Thyroid cancer. The companies which have their Thyroid cancer drug candidates in the most advanced stage, i.e. phase III include, Suzhou Zelgen Biopharmaceuticals.
  • Phases
DelveInsight’s report covers around 35+ products under different phases of clinical development like
  • Late stage products (Phase III)
  • Mid-stage products (Phase II)
  • Early-stage product (Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates
  • Route of Administration
Thyroid cancer pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
  • Oral
  • Parenteral
  • Intravenous
  • Subcutaneous
  • Topical.
  • Molecule Type
Products have been categorized under various Molecule types such as
  • Monoclonal Antibody
  • Peptides
  • Polymer
  • Small molecule
  • Gene therapy
  • Product Type
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Thyroid cancer: Pipeline Development Activities

The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Thyroid cancer therapeutic drugs key players involved in developing key drugs.

Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Thyroid cancer drugs.

Thyroid cancer Report Insights
  • Thyroid cancer Pipeline Analysis
  • Therapeutic Assessment
  • Unmet Needs
  • Impact of Drugs
Thyroid cancer Report Assessment
  • Pipeline Product Profiles
  • Therapeutic Assessment
  • Pipeline Assessment
  • Inactive drugs assessment
  • Unmet Needs
Key Questions

Current Treatment Scenario and Emerging Therapies:
  • How many companies are developing Thyroid cancer drugs?
  • How many Thyroid cancer drugs are developed by each company?
  • How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Thyroid cancer?
  • What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Thyroid cancer therapeutics?
  • What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Thyroid cancer and their status?
  • What are the key designations that have been granted to the emerging drugs?
Key Players
  • Suzhou Zelgen Biopharmaceuticals
  • Jiangsu Chia-Tai Tianqing Pharmaceutical
  • Takeda
  • Bristol-Myers Squibb
  • Genentech
  • AffyImmune Therapeutics, Inc.
  • Taizhou Hanzhong biomedical co. LTD
  • NantCell, Inc.
  • Bayer
  • Merck Sharp & Dohme Corp.
  • Pfizer
  • MedImmune LLC
  • CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
  • Eisai Inc.
  • cCAM Biotherapeutics
  • Purple Biotech Ltd.
  • Turning Point Therapeutics, Inc.
  • Hoffmann-La Roche
  • Bicara Therapeutics
  • Novartis
  • GlobeImmune
  • GE Healthcare
  • IBC Pharmaceuticals
  • Debiopharm
  • Blueprint Medicines
  • Ono Pharmaceutical
  • Array BioPharma
  • Hutchison MediPharma
  • Celldex Therapeutics Inc
  • VBL Therapeutics
  • Biovista
Key Products
  • Donafenib
  • Anlotinib
  • Ponatinib
  • Nivolumab
  • Atezolizumab
  • AIC100
  • HX008
  • GI-6207
  • Ipilimumab
  • Regorafenib
  • MLN0128
  • Pembrolizumab
  • SU011248
  • Durvalumab
  • HA121-28
  • Ifosfamide
  • CM-24
  • ETBX-011
  • TPX-0046
  • Entrectinib
  • BCA101
  • Spartalizumab
  • GI 6207
  • EMI 137
  • Abemaciclib
  • DEBIO 1124
  • Gavreto
  • Encorafenib
  • Binimetinib
  • Surufatinib
  • CDX-3379
  • VB-111
  • BVA 701
Introduction
Executive Summary
Thyroid cancer: Overview
  Causes
  Mechanism of Action
  Signs and Symptoms
  Diagnosis
  Disease Management
Pipeline Therapeutics
  Comparative Analysis
Therapeutic Assessment
  Assessment by Product Type
  Assessment by Stage and Product Type
  Assessment by Route of Administration
  Assessment by Stage and Route of Administration
  Assessment by Molecule Type
  Assessment by Stage and Molecule Type
Thyroid cancer – DelveInsight’s Analytical Perspective
In-depth Commercial Assessment
  Thyroid cancer companies’ collaborations, Licensing, Acquisition -Deal Value Trends
Thyroid cancer Collaboration Deals
  Company-Company Collaborations (Licensing / Partnering) Analysis
  Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Phase III)
  Comparative Analysis
Donafenib: Suzhou Zelgen Biopharmaceuticals
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report..
Mid Stage Products (Phase II)
  Comparative Analysis
Ponatinib: Takeda
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report..
Early Stage Products (Phase I)
  Comparative Analysis
AIC100: AffyImmune Therapeutics
  Product Description
  Research and Development
  Product Development Activities
Drug profiles in the detailed report..

Inactive Products
  Comparative Analysis
Thyroid cancer Key Companies
Thyroid cancer Key Products
Thyroid cancer- Unmet Needs
Thyroid cancer- Market Drivers and Barriers
Thyroid cancer- Future Perspectives and Conclusion
Thyroid cancer Analyst Views
Thyroid cancer Key Companies
Appendix

LIST OF TABLES

Table 1 Total Products for Thyroid cancer
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products


LIST OF FIGURES

Figure 1 Total Products for Thyroid cancer
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products


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