Superoxide Dismutase [Cu-Zn] - Pipeline Review, H2 2019
Superoxide Dismutase [Cu-Zn] - Pipeline Review, H2 2019
SUMMARY
Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) pipeline Target constitutes close to 19 molecules. Out of which approximately 15 molecules are developed by companies and remaining by the universities/institutes. The latest report Superoxide Dismutase [Cu-Zn] - Pipeline Review, H2 2019, outlays comprehensive information on the Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.
Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) - Superoxide dismutase (SOD) is an enzyme that alternately catalyzes the dismutation of the superoxide (O2?) radical into either ordinary molecular oxygen (O2) or hydrogen peroxide (H2O2) which prevents damage to tissues. Superoxide dismutase is used for treating pain and swelling (inflammation) caused by osteoarthritis, sports injuries, and rheumatoid arthritis, a kidney condition called interstitial cystitis, gout, poisoning caused by a weed-killer called paraquat, cancer, and lung problems in newborns. The molecules developed by companies in Phase III, Phase I, Preclinical and Discovery stages are 3, 1, 9 and 2 respectively. Similarly, the universities portfolio in Preclinical and Discovery stages comprises 3 and 1 molecules, respectively. Report covers products from therapy areas Central Nervous System and Genetic Disorders which include indications Amyotrophic Lateral Sclerosis, Neurodegenerative Diseases, Parkinson's Disease and Wilson Disease.
Furthermore, this report also reviews key players involved in Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) targeted therapeutics development with respective active and dormant or discontinued projects. Driven by data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources.
SCOPE
SUMMARY
Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) pipeline Target constitutes close to 19 molecules. Out of which approximately 15 molecules are developed by companies and remaining by the universities/institutes. The latest report Superoxide Dismutase [Cu-Zn] - Pipeline Review, H2 2019, outlays comprehensive information on the Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.
Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) - Superoxide dismutase (SOD) is an enzyme that alternately catalyzes the dismutation of the superoxide (O2?) radical into either ordinary molecular oxygen (O2) or hydrogen peroxide (H2O2) which prevents damage to tissues. Superoxide dismutase is used for treating pain and swelling (inflammation) caused by osteoarthritis, sports injuries, and rheumatoid arthritis, a kidney condition called interstitial cystitis, gout, poisoning caused by a weed-killer called paraquat, cancer, and lung problems in newborns. The molecules developed by companies in Phase III, Phase I, Preclinical and Discovery stages are 3, 1, 9 and 2 respectively. Similarly, the universities portfolio in Preclinical and Discovery stages comprises 3 and 1 molecules, respectively. Report covers products from therapy areas Central Nervous System and Genetic Disorders which include indications Amyotrophic Lateral Sclerosis, Neurodegenerative Diseases, Parkinson's Disease and Wilson Disease.
Furthermore, this report also reviews key players involved in Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) targeted therapeutics development with respective active and dormant or discontinued projects. Driven by data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources.
SCOPE
- The report provides a snapshot of the global therapeutic landscape for Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1)
- The report reviews Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved in Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) targeted therapeutics and enlists all their major and minor projects
- The report assesses Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
- The report summarizes all the dormant and discontinued pipeline projects
- The report reviews latest news and deals related to Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) targeted therapeutics
- Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Identify and understand the targeted therapy areas and indications for Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1)
- Identify the use of drugs for target identification and drug repurposing
- Identify potential new clients or partners in the target demographic
- Develop strategic initiatives by understanding the focus areas of leading companies
- Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
- Devise corrective measures for pipeline projects by understanding Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) development landscape
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
Introduction
Global Markets Direct Report Coverage
Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) - Overview
Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) - Therapeutics Development
Products under Development by Stage of Development
Products under Development by Therapy Area
Products under Development by Indication
Products under Development by Companies
Products under Development by Universities/Institutes
Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) - Therapeutics Assessment
Assessment by Mechanism of Action
Assessment by Route of Administration
Assessment by Molecule Type
Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) - Companies Involved in Therapeutics Development
AL-S Pharma AG
Alexion Pharmaceuticals Inc
Alnylam Pharmaceuticals Inc
Apic Bio Inc
AveXis Inc
Biogen Inc
Collaborative Medicinal Development LLC
Priavoid GmbH
ProMIS Neurosciences Inc
Thera Neuropharma Inc
Trucode Gene Repair Inc
Voyager Therapeutics Inc
Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) - Drug Profiles
Antisense RNAi Oligonucleotides to Inhibit Superoxide Dismutase for CNS Disorders - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
AP-101 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
APB-102 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
AVXS-301 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Monoclonal Antibody to Inhibit SOD1 for Amyotropic Lateral Sclerosis - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Oligonucleotides to Activate SOD1 for Amyotropic Lateral Sclerosis - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
PMN-110 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
PMN-120 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
PMN-130 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
RNAi Gene Therapy to Inhibit SOD1 for Amyotrophic Lateral Sclerosis - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Small Molecule to Activate SOD-1 for Amyotrophic Lateral Sclerosis and Parkinson's Disease - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Small Molecule to Inhibit Superoxide Dismutase 1 for Amyotrophic Lateral Sclerosis - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Synthetic Peptide to Inhibit SOD1 for Amyotrophic Lateral Sclerosis - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
TDI-186 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
THN-1 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
tiomolibdate choline - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
tofersen sodium - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
VYSOD-101 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
VYSOD-102 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) - Dormant Products
Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) - Product Development Milestones
Featured News & Press Releases
Oct 16, 2019: Neurimmune and TVM Capital Life Science announce the initiation of AL-S Pharma's phase 1 study of AP-101 for the treatment of ALS
Oct 14, 2019: Collaborative Medicinal Development enrolls first patient in a randomized, placebo-controlled clinical trial of CuATSM for The treatment of Amyotrophic Lateral Sclerosis
Jul 22, 2019: Apic Bio’s APB-102 receives Orphan Drug Designation from the FDA for the treatment of genetic SOD1 ALS
Jul 01, 2019: Copper compound shows further potential as therapy for slowing ALS
Jun 10, 2019: Collaborative Medicinal Development reports that lead drug shows dose-dependent improvement in Parkinson's disease
May 03, 2019: Biogen reports positive data from Phase I/II study of tofersen
May 02, 2019: Experimental drug shows promise for genetic form of ALS
Apr 29, 2019: Voyager Therapeutics Announces New Data on VY-SOD102 at the American Society of Gene and Cell Therapy 2019 Annual Meeting
Apr 17, 2019: Collaborative Medicinal Development wins AU$1 million grant award from FightMND
Jan 14, 2019: Researchers report positive results from motor neurone disease trial
Jan 07, 2019: Collaborative Medicinal Development reports that lead drug modifies ALS progression
Dec 17, 2018: Biogen provides update on SOD1 phase I Antisense trial
Oct 16, 2018: Voyager Therapeutics announces preclinical data for Amyotrophic Lateral Sclerosis at the Congress of the European Society of Gene and Cell Therapy
Jul 25, 2018: Next-generation ALS drug silences inherited form of the disease in animal models
Jul 16, 2018: Washington University’s new ALS therapy in clinical trial stage
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
Contact Us
Disclaimer
Global Markets Direct Report Coverage
Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) - Overview
Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) - Therapeutics Development
Products under Development by Stage of Development
Products under Development by Therapy Area
Products under Development by Indication
Products under Development by Companies
Products under Development by Universities/Institutes
Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) - Therapeutics Assessment
Assessment by Mechanism of Action
Assessment by Route of Administration
Assessment by Molecule Type
Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) - Companies Involved in Therapeutics Development
AL-S Pharma AG
Alexion Pharmaceuticals Inc
Alnylam Pharmaceuticals Inc
Apic Bio Inc
AveXis Inc
Biogen Inc
Collaborative Medicinal Development LLC
Priavoid GmbH
ProMIS Neurosciences Inc
Thera Neuropharma Inc
Trucode Gene Repair Inc
Voyager Therapeutics Inc
Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) - Drug Profiles
Antisense RNAi Oligonucleotides to Inhibit Superoxide Dismutase for CNS Disorders - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
AP-101 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
APB-102 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
AVXS-301 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Monoclonal Antibody to Inhibit SOD1 for Amyotropic Lateral Sclerosis - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Oligonucleotides to Activate SOD1 for Amyotropic Lateral Sclerosis - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
PMN-110 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
PMN-120 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
PMN-130 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
RNAi Gene Therapy to Inhibit SOD1 for Amyotrophic Lateral Sclerosis - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Small Molecule to Activate SOD-1 for Amyotrophic Lateral Sclerosis and Parkinson's Disease - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Small Molecule to Inhibit Superoxide Dismutase 1 for Amyotrophic Lateral Sclerosis - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Synthetic Peptide to Inhibit SOD1 for Amyotrophic Lateral Sclerosis - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
TDI-186 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
THN-1 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
tiomolibdate choline - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
tofersen sodium - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
VYSOD-101 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
VYSOD-102 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) - Dormant Products
Superoxide Dismutase [Cu-Zn] (Superoxide Dismutase 1 or Epididymis Secretory Protein Li 44 or SOD1 or EC 1.15.1.1) - Product Development Milestones
Featured News & Press Releases
Oct 16, 2019: Neurimmune and TVM Capital Life Science announce the initiation of AL-S Pharma's phase 1 study of AP-101 for the treatment of ALS
Oct 14, 2019: Collaborative Medicinal Development enrolls first patient in a randomized, placebo-controlled clinical trial of CuATSM for The treatment of Amyotrophic Lateral Sclerosis
Jul 22, 2019: Apic Bio’s APB-102 receives Orphan Drug Designation from the FDA for the treatment of genetic SOD1 ALS
Jul 01, 2019: Copper compound shows further potential as therapy for slowing ALS
Jun 10, 2019: Collaborative Medicinal Development reports that lead drug shows dose-dependent improvement in Parkinson's disease
May 03, 2019: Biogen reports positive data from Phase I/II study of tofersen
May 02, 2019: Experimental drug shows promise for genetic form of ALS
Apr 29, 2019: Voyager Therapeutics Announces New Data on VY-SOD102 at the American Society of Gene and Cell Therapy 2019 Annual Meeting
Apr 17, 2019: Collaborative Medicinal Development wins AU$1 million grant award from FightMND
Jan 14, 2019: Researchers report positive results from motor neurone disease trial
Jan 07, 2019: Collaborative Medicinal Development reports that lead drug modifies ALS progression
Dec 17, 2018: Biogen provides update on SOD1 phase I Antisense trial
Oct 16, 2018: Voyager Therapeutics announces preclinical data for Amyotrophic Lateral Sclerosis at the Congress of the European Society of Gene and Cell Therapy
Jul 25, 2018: Next-generation ALS drug silences inherited form of the disease in animal models
Jul 16, 2018: Washington University’s new ALS therapy in clinical trial stage
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
Contact Us
Disclaimer
LIST OF TABLES
Number of Products under Development by Stage of Development, H2 2019
Number of Products under Development by Therapy Areas, H2 2019
Number of Products under Development by Indication, H2 2019
Number of Products under Development by Companies, H2 2019
Products under Development by Companies, H2 2019
Products under Development by Companies, H2 2019 (Contd..1), H2 2019
Number of Products under Investigation by Universities/Institutes, H2 2019
Products under Investigation by Universities/Institutes, H2 2019
Number of Products by Stage and Mechanism of Actions, H2 2019
Number of Products by Stage and Route of Administration, H2 2019
Number of Products by Stage and Molecule Type, H2 2019
Pipeline by AL-S Pharma AG, H2 2019
Pipeline by Alexion Pharmaceuticals Inc, H2 2019
Pipeline by Alnylam Pharmaceuticals Inc, H2 2019
Pipeline by Apic Bio Inc, H2 2019
Pipeline by AveXis Inc, H2 2019
Pipeline by Biogen Inc, H2 2019
Pipeline by Collaborative Medicinal Development LLC, H2 2019
Pipeline by Priavoid GmbH, H2 2019
Pipeline by ProMIS Neurosciences Inc, H2 2019
Pipeline by Thera Neuropharma Inc, H2 2019
Pipeline by Trucode Gene Repair Inc, H2 2019
Pipeline by Voyager Therapeutics Inc, H2 2019
Dormant Projects, H2 2019
Number of Products under Development by Stage of Development, H2 2019
Number of Products under Development by Therapy Areas, H2 2019
Number of Products under Development by Indication, H2 2019
Number of Products under Development by Companies, H2 2019
Products under Development by Companies, H2 2019
Products under Development by Companies, H2 2019 (Contd..1), H2 2019
Number of Products under Investigation by Universities/Institutes, H2 2019
Products under Investigation by Universities/Institutes, H2 2019
Number of Products by Stage and Mechanism of Actions, H2 2019
Number of Products by Stage and Route of Administration, H2 2019
Number of Products by Stage and Molecule Type, H2 2019
Pipeline by AL-S Pharma AG, H2 2019
Pipeline by Alexion Pharmaceuticals Inc, H2 2019
Pipeline by Alnylam Pharmaceuticals Inc, H2 2019
Pipeline by Apic Bio Inc, H2 2019
Pipeline by AveXis Inc, H2 2019
Pipeline by Biogen Inc, H2 2019
Pipeline by Collaborative Medicinal Development LLC, H2 2019
Pipeline by Priavoid GmbH, H2 2019
Pipeline by ProMIS Neurosciences Inc, H2 2019
Pipeline by Thera Neuropharma Inc, H2 2019
Pipeline by Trucode Gene Repair Inc, H2 2019
Pipeline by Voyager Therapeutics Inc, H2 2019
Dormant Projects, H2 2019
LIST OF FIGURES
Number of Products under Development by Stage of Development, H2 2019
Number of Products under Development by Therapy Areas, H2 2019
Number of Products under Development by Top 10 Indications, H2 2019
Number of Products by Mechanism of Actions, H2 2019
Number of Products by Stage and Mechanism of Actions, H2 2019
Number of Products by Routes of Administration, H2 2019
Number of Products by Stage and Routes of Administration, H2 2019
Number of Products by Molecule Types, H2 2019
Number of Products by Stage and Molecule Types, H2 2019
COMPANIES MENTIONED
AL-S Pharma AG
Alexion Pharmaceuticals Inc
Alnylam Pharmaceuticals Inc
Apic Bio Inc
AveXis Inc
Biogen Inc
Collaborative Medicinal Development LLC
Priavoid GmbH
ProMIS Neurosciences Inc
Thera Neuropharma Inc
Trucode Gene Repair Inc
Voyager Therapeutics Inc
Number of Products under Development by Stage of Development, H2 2019
Number of Products under Development by Therapy Areas, H2 2019
Number of Products under Development by Top 10 Indications, H2 2019
Number of Products by Mechanism of Actions, H2 2019
Number of Products by Stage and Mechanism of Actions, H2 2019
Number of Products by Routes of Administration, H2 2019
Number of Products by Stage and Routes of Administration, H2 2019
Number of Products by Molecule Types, H2 2019
Number of Products by Stage and Molecule Types, H2 2019
COMPANIES MENTIONED
AL-S Pharma AG
Alexion Pharmaceuticals Inc
Alnylam Pharmaceuticals Inc
Apic Bio Inc
AveXis Inc
Biogen Inc
Collaborative Medicinal Development LLC
Priavoid GmbH
ProMIS Neurosciences Inc
Thera Neuropharma Inc
Trucode Gene Repair Inc
Voyager Therapeutics Inc
