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Somatotropin Deficiency Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

May 2024 | 133 pages | ID: SC2E3E2B1864EN
IMARC Group

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The 7 major somatotropin deficiency markets are expected to exhibit a CAGR of 3.99% during 2024-2034.

The somatotropin deficiency market has been comprehensively analyzed in IMARC's new report titled "Somatotropin Deficiency Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Somatotropin deficiency refers to a medical condition characterized by insufficient production or secretion of growth hormone by the pituitary gland. This hormone is responsible for stimulating physical development and growth as well as regulating several metabolic processes. In children, somatotropin deficiency can lead to growth retardation, resulting in shorter stature compared to their peers. Various other common signs and symptoms of the illness in children include delayed puberty, decreased muscle mass, increased body fat, slow tooth development, etc. Adults suffering from this ailment might experience reduced energy levels and strength, enhanced fat around the waist, impaired memory and concentration, changes in lipid profiles, etc. The diagnosis of somatotropin deficiency involves medical history evaluation, physical examination, and specific laboratory tests to measure growth hormone levels. A healthcare provider may also perform magnetic resonance imaging (MRI) of the brain to visualize the structure of the pituitary gland and rule out any other abnormalities, such as tumors or malformations, that may affect the production of hormones. In some cases, genetic testing will be recommended to identify specific gene mutations associated with this disease.

The increasing cases of tumors or injuries in the pituitary gland or the hypothalamus, which can damage the tissues or disrupt their normal functioning, are primarily driving the somatotropin deficiency market. In addition to this, the rising incidences of genetic mutations that can affect the production, secretion, or processing of the growth hormone are also creating a positive outlook for the market. Moreover, the inflating demand for subcutaneous injections of recombinant human growth hormone (rhGH), owing to their various benefits, like convenient administration, stable absorption, improved compliance, etc., is further bolstering the market growth. Apart from this, the widespread adoption of high-intensity interval training programs, since they stimulate the release of GH in patients, thereby promoting muscle strength, tissue repair, and metabolism, is acting as another significant growth-inducing factor. Additionally, the emerging popularity of regenerative medicine techniques, which aim to heal damaged or dysfunctional cells to potentially enhance overall body growth in individuals suffering from the disease, is expected to drive the somatotropin deficiency market during the forecast period.

IMARC Group's new report provides an exhaustive analysis of the somatotropin deficiency market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for somatotropin deficiency and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the somatotropin deficiency market in any manner.

Time Period of the Study

Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034

Countries Covered

United States
Germany
France
United Kingdom
Italy
Spain
Japan

Analysis Covered Across Each Country

Historical, current, and future epidemiology scenario
Historical, current, and future performance of the somatotropin deficiency market
Historical, current, and future performance of various therapeutic categories in the market
Sales of various drugs across the somatotropin deficiency market
Reimbursement scenario in the market
In-market and pipeline drugs
Competitive Landscape:
This report also provides a detailed analysis of the current somatotropin deficiency marketed drugs and late-stage pipeline drugs.

In-Market Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.

Key Questions Answered in this Report:
Market Insights

How has the somatotropin deficiency market performed so far and how will it perform in the coming years?
What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
What was the country-wise size of the somatotropin deficiency market across the seven major markets in 2023 and what will it look like in 2034?
What is the growth rate of the somatotropin deficiency market across the seven major markets and what will be the expected growth over the next ten years?
What are the key unmet needs in the market?

Epidemiology Insights

What is the number of prevalent cases (2018-2034) of somatotropin deficiency across the seven major markets?
What is the number of prevalent cases (2018-2034) of somatotropin deficiency by age across the seven major markets?
What is the number of prevalent cases (2018-2034) of somatotropin deficiency by gender across the seven major markets?
How many patients are diagnosed (2018-2034) with somatotropin deficiency across the seven major markets?
What is the size of the somatotropin deficiency patient pool (2018-2023) across the seven major markets?
What would be the forecasted patient pool (2024-2034) across the seven major markets?
What are the key factors driving the epidemiological trend of somatotropin deficiency?
What will be the growth rate of patients across the seven major markets?

Somatotropin Deficiency: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

What are the current marketed drugs and what are their market performance?
What are the key pipeline drugs and how are they expected to perform in the coming years?
How safe are the current marketed drugs and what are their efficacies?
How safe are the late-stage pipeline drugs and what are their efficacies?
What are the current treatment guidelines for somatotropin deficiency drugs across the seven major markets?
Who are the key companies in the market and what are their market shares?
What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the somatotropin deficiency market?
What are the key regulatory events related to the somatotropin deficiency market?
What is the structure of clinical trial landscape by status related to the somatotropin deficiency market?
What is the structure of clinical trial landscape by phase related to the somatotropin deficiency market?
What is the structure of clinical trial landscape by route of administration related to the somatotropin deficiency market?
1 PREFACE

2 SCOPE AND METHODOLOGY

2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
  2.3.1 Primary Sources
  2.3.2 Secondary Sources
2.4 Market Estimation
  2.4.1 Bottom-Up Approach
  2.4.2 Top-Down Approach
2.5 Forecasting Methodology

3 EXECUTIVE SUMMARY

4 SOMATOTROPIN DEFICIENCY - INTRODUCTION

4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence

5 SOMATOTROPIN DEFICIENCY - DISEASE OVERVIEW

5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment

6 PATIENT JOURNEY

7 SOMATOTROPIN DEFICIENCY - EPIDEMIOLOGY AND PATIENT POPULATION

7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
  7.2.1 Epidemiology Scenario (2018-2023)
  7.2.2 Epidemiology Forecast (2024-2034)
  7.2.3 Epidemiology by Age (2018-2034)
  7.2.4 Epidemiology by Gender (2018-2034)
  7.2.5 Diagnosed Cases (2018-2034)
  7.2.6 Patient Pool/Treated Cases (2018-2034)
7.3 Epidemiology Scenario - United States
  7.3.1 Epidemiology Scenario (2018-2023)
  7.3.2 Epidemiology Forecast (2024-2034)
  7.3.3 Epidemiology by Age (2018-2034)
  7.3.4 Epidemiology by Gender (2018-2034)
  7.3.5 Diagnosed Cases (2018-2034)
  7.3.6 Patient Pool/Treated Cases (2018-2034)
7.4 Epidemiology Scenario - Germany
  7.4.1 Epidemiology Scenario (2018-2023)
  7.4.2 Epidemiology Forecast (2024-2034)
  7.4.3 Epidemiology by Age (2018-2034)
  7.4.4 Epidemiology by Gender (2018-2034)
  7.4.5 Diagnosed Cases (2018-2034)
  7.4.6 Patient Pool/Treated Cases (2018-2034)
7.5 Epidemiology Scenario - France
  7.5.1 Epidemiology Scenario (2018-2023)
  7.5.2 Epidemiology Forecast (2024-2034)
  7.5.3 Epidemiology by Age (2018-2034)
  7.5.4 Epidemiology by Gender (2018-2034)
  7.5.5 Diagnosed Cases (2018-2034)
  7.5.6 Patient Pool/Treated Cases (2018-2034)
7.6 Epidemiology Scenario - United Kingdom
  7.6.1 Epidemiology Scenario (2018-2023)
  7.6.2 Epidemiology Forecast (2024-2034)
  7.6.3 Epidemiology by Age (2018-2034)
  7.6.4 Epidemiology by Gender (2018-2034)
  7.6.5 Diagnosed Cases (2018-2034)
  7.6.6 Patient Pool/Treated Cases (2018-2034)
7.7 Epidemiology Scenario - Italy
  7.7.1 Epidemiology Scenario (2018-2023)
  7.7.2 Epidemiology Forecast (2024-2034)
  7.7.3 Epidemiology by Age (2018-2034)
  7.7.4 Epidemiology by Gender (2018-2034)
  7.7.5 Diagnosed Cases (2018-2034)
  7.7.6 Patient Pool/Treated Cases (2018-2034)
7.8 Epidemiology Scenario - Spain
  7.8.1 Epidemiology Scenario (2018-2023)
  7.8.2 Epidemiology Forecast (2024-2034)
  7.8.3 Epidemiology by Age (2018-2034)
  7.8.4 Epidemiology by Gender (2018-2034)
  7.8.5 Diagnosed Cases (2018-2034)
  7.8.6 Patient Pool/Treated Cases (2018-2034)
7.9 Epidemiology Scenario - Japan
  7.9.1 Epidemiology Scenario (2018-2023)
  7.9.2 Epidemiology Forecast (2024-2034)
  7.9.3 Epidemiology by Age (2018-2034)
  7.9.4 Epidemiology by Gender (2018-2034)
  7.9.5 Diagnosed Cases (2018-2034)
  7.9.6 Patient Pool/Treated Cases (2018-2034)

8 SOMATOTROPIN DEFICIENCY - TREATMENT ALGORITHM, GUIDELINES, AND MEDICAL PRACTICES

8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm

9 SOMATOTROPIN DEFICIENCY - UNMET NEEDS

10 SOMATOTROPIN DEFICIENCY - KEY ENDPOINTS OF TREATMENT

11 SOMATOTROPIN DEFICIENCY - MARKETED PRODUCTS

11.1 List of Somatotropin Deficiency Marketed Drugs Across the Top 7 Markets
  11.1.1 Humatrope (Somatropin) - Eli Lilly and Company
    11.1.1.1 Drug Overview
    11.1.1.2 Mechanism of Action
    11.1.1.3 Regulatory Status
    11.1.1.4 Clinical Trial Results
    11.1.1.5 Sales Across Major Markets
  11.1.2 Macrilen (Macimorelin) - AEterna Zentaris
    11.1.2.1 Drug Overview
    11.1.2.2 Mechanism of Action
    11.1.2.3 Regulatory Status
    11.1.2.4 Clinical Trial Results
    11.1.2.5 Sales Across Major Markets
  11.1.3 NutropinAq (Somatropin) - Genentech
    11.1.3.1 Drug Overview
    11.1.3.2 Mechanism of Action
    11.1.3.3 Regulatory Status
    11.1.3.4 Clinical Trial Results
    11.1.3.5 Sales Across Major Markets
  11.1.4 Zomacton (Somatropin) - Ferring Pharmaceuticals
    11.1.4.1 Drug Overview
    11.1.4.2 Mechanism of Action
    11.1.4.3 Regulatory Status
    11.1.4.4 Clinical Trial Results
    11.1.4.5 Sales Across Major Markets
  11.1.5 Sogroya (Somapacitan) - Novo Nordisk
    11.1.5.1 Drug Overview
    11.1.5.2 Mechanism of Action
    11.1.5.3 Regulatory Status
    11.1.5.4 Clinical Trial Results
    11.1.5.5 Sales Across Major Markets
Kindly note that the above only represents a partial list of marketed drugs, and the complete list has been provided in the report.

12 SOMATOTROPIN DEFICIENCY - PIPELINE DRUGS

12.1 List of Somatotropin Deficiency Pipeline Drugs Across the Top 7 Markets
  12.1.1 LUM 201 - Lumos Pharma/Merck
    12.1.1.1 Drug Overview
    12.1.1.2 Mechanism of Action
    12.1.1.3 Clinical Trial Results
    12.1.1.4 Safety and Efficacy
    12.1.1.5 Regulatory Status
Kindly note that the above only represents a partial list of pipeline drugs, and the complete list has been provided in the report.

13. SOMATOTROPIN DEFICIENCY - ATTRIBUTE ANALYSIS OF KEY MARKETED AND PIPELINE DRUGS

14. SOMATOTROPIN DEFICIENCY – CLINICAL TRIAL LANDSCAPE

14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events

15 SOMATOTROPIN DEFICIENCY - MARKET SCENARIO

15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
  15.2.1 Somatotropin Deficiency - Market Size
    15.2.1.1 Market Size (2018-2023)
    15.2.1.2 Market Forecast (2024-2034)
  15.2.2 Somatotropin Deficiency - Market Size by Therapies
    15.2.2.1 Market Size by Therapies (2018-2023)
    15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
  15.3.1 Somatotropin Deficiency - Market Size
    15.3.1.1 Market Size (2018-2023)
    15.3.1.2 Market Forecast (2024-2034)
  15.3.2 Somatotropin Deficiency - Market Size by Therapies
    15.3.2.1 Market Size by Therapies (2018-2023)
    15.3.2.2 Market Forecast by Therapies (2024-2034)
  15.3.3 Somatotropin Deficiency - Access and Reimbursement Overview
15.4 Market Scenario - Germany
  15.4.1 Somatotropin Deficiency - Market Size
    15.4.1.1 Market Size (2018-2023)
    15.4.1.2 Market Forecast (2024-2034)
  15.4.2 Somatotropin Deficiency - Market Size by Therapies
    15.4.2.1 Market Size by Therapies (2018-2023)
    15.4.2.2 Market Forecast by Therapies (2024-2034)
  15.4.3 Somatotropin Deficiency - Access and Reimbursement Overview
15.5 Market Scenario - France
  15.5.1 Somatotropin Deficiency - Market Size
    15.5.1.1 Market Size (2018-2023)
    15.5.1.2 Market Forecast (2024-2034)
  15.5.2 Somatotropin Deficiency - Market Size by Therapies
    15.5.2.1 Market Size by Therapies (2018-2023)
    15.5.2.2 Market Forecast by Therapies (2024-2034)
  15.5.3 Somatotropin Deficiency - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
  15.6.1 Somatotropin Deficiency - Market Size
    15.6.1.1 Market Size (2018-2023)
    15.6.1.2 Market Forecast (2024-2034)
  15.6.2 Somatotropin Deficiency - Market Size by Therapies
    15.6.2.1 Market Size by Therapies (2018-2023)
    15.6.2.2 Market Forecast by Therapies (2024-2034)
  15.6.3 Somatotropin Deficiency - Access and Reimbursement Overview
15.7 Market Scenario - Italy
  15.7.1 Somatotropin Deficiency - Market Size
    15.7.1.1 Market Size (2018-2023)
    15.7.1.2 Market Forecast (2024-2034)
  15.7.2 Somatotropin Deficiency - Market Size by Therapies
    15.7.2.1 Market Size by Therapies (2018-2023)
    15.7.2.2 Market Forecast by Therapies (2024-2034)
  15.7.3 Somatotropin Deficiency - Access and Reimbursement Overview
15.8 Market Scenario - Spain
  15.8.1 Somatotropin Deficiency - Market Size
    15.8.1.1 Market Size (2018-2023)
    15.8.1.2 Market Forecast (2024-2034)
  15.8.2 Somatotropin Deficiency - Market Size by Therapies
    15.8.2.1 Market Size by Therapies (2018-2023)
    15.8.2.2 Market Forecast by Therapies (2024-2034)
  15.8.3 Somatotropin Deficiency - Access and Reimbursement Overview
15.9 Market Scenario - Japan
  15.9.1 Somatotropin Deficiency - Market Size
    15.9.1.1 Market Size (2018-2023)
    15.9.1.2 Market Forecast (2024-2034)
  15.9.2 Somatotropin Deficiency - Market Size by Therapies
    15.9.2.1 Market Size by Therapies (2018-2023)
    15.9.2.2 Market Forecast by Therapies (2024-2034)
  15.9.3 Somatotropin Deficiency - Access and Reimbursement Overview

16 SOMATOTROPIN DEFICIENCY - RECENT EVENTS AND INPUTS FROM KEY OPINION LEADERS

17 SOMATOTROPIN DEFICIENCY MARKET - SWOT ANALYSIS

17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats

18 SOMATOTROPIN DEFICIENCY MARKET – STRATEGIC RECOMMENDATIONS

19 APPENDIX


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