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Restless Legs Syndrome Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

May 2024 | 130 pages | ID: RA04D34B6CBBEN
IMARC Group

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The 7 major restless legs syndrome markets are expected to exhibit a CAGR of 2.49% during 2024-2034.

The restless legs syndrome market has been comprehensively analyzed in IMARC's new report titled "Restless Legs Syndrome Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Restless legs syndrome refers to a neurological disorder characterized by uncomfortable sensations in the legs, leading to an irresistible urge to move them. These sensations generally range from mild to severe and can interfere with sleep as well as daily activities. In addition to the impulse to move the legs, some people might experience involuntary leg movements during sleep, known as periodic limb movements of sleep (PLMS). The symptoms of the ailment may worsen in the evening or at night and might be exacerbated by stress, anxiety, or prolonged sitting or standing. Diagnosing restless legs syndrome can be challenging since there is no single test that can definitively confirm the condition. However, a diagnosis of the disorder is typically based on a combination of medical history and clinical indications. Doctors will ask about the patient's symptoms, including the nature and frequency of leg sensations, as well as any family history of the condition. In some cases, they may recommend blood tests to check for iron deficiency, which has been associated with an increased risk of the ailment.

The rising cases of dopamine dysfunction, which causes muscle spasms and involuntary movements, are primarily driving the restless legs syndrome market. In addition to this, the increasing prevalence of various associated risk factors, such as peripheral neuropathy, iron deficiency, spinal cord disorders, sleep deprivation, excessive alcohol consumption, etc., is also bolstering the market growth. Moreover, the widespread adoption of benzodiazepines, including clonazepam and diazepam, to help improve sleep quality and provide symptom relief in patients is acting as another significant growth-inducing factor. Besides this, the inflating demand for anticonvulsants that aid in reducing the sensory and motor symptoms of the ailment, such as the uncomfortable sensations accompanying the condition, is also creating a positive outlook for the market. Additionally, the emerging popularity of non-pharmacological treatments, including exercise, massage, stretching, etc., since they improve circulation, reduce stress, and promote relaxation, which can all contribute to enhancing sleep quality, is augmenting the market growth. Furthermore, the escalating utilization of neuroimaging techniques, such as functional magnetic resonance imaging (fMRI), to identify regions of the brain that are involved in the sensation of leg discomfort and the urge to move the legs is expected to drive the restless legs syndrome market in the coming years.

IMARC Group's new report provides an exhaustive analysis of the restless legs syndrome market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for restless legs syndrome and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the restless legs syndrome market in any manner.

Time Period of the Study

Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034

Countries Covered

United States
Germany
France
United Kingdom
Italy
Spain
Japan

Analysis Covered Across Each Country

Historical, current, and future epidemiology scenario
Historical, current, and future performance of the restless legs syndrome market
Historical, current, and future performance of various therapeutic categories in the market
Sales of various drugs across the restless legs syndrome market
Reimbursement scenario in the market
In-market and pipeline drugs
Competitive Landscape:
This report also provides a detailed analysis of the current restless legs syndrome marketed drugs and late-stage pipeline drugs.

In-Market Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance


Late-Stage Pipeline Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.

Key Questions Answered in this Report:
Market Insights

How has the restless legs syndrome market performed so far and how will it perform in the coming years?
What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
What was the country-wise size of the restless legs syndrome market across the seven major markets in 2023 and what will it look like in 2034?
What is the growth rate of the restless legs syndrome market across the seven major markets and what will be the expected growth over the next ten years?
What are the key unmet needs in the market?

Epidemiology Insights

What is the number of prevalent cases (2018-2034) of restless legs syndrome across the seven major markets?
What is the number of prevalent cases (2018-2034) of restless legs syndrome by age across the seven major markets?
What is the number of prevalent cases (2018-2034) of restless legs syndrome by gender across the seven major markets?
How many patients are diagnosed (2018-2034) with restless legs syndrome across the seven major markets?
What is the size of the restless legs syndrome patient pool (2018-2023) across the seven major markets?
What would be the forecasted patient pool (2024-2034) across the seven major markets?
What are the key factors driving the epidemiological trend of restless legs syndrome?
What will be the growth rate of patients across the seven major markets?

Restless Legs Syndrome: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

What are the current marketed drugs and what are their market performance?
What are the key pipeline drugs and how are they expected to perform in the coming years?
How safe are the current marketed drugs and what are their efficacies?
How safe are the late-stage pipeline drugs and what are their efficacies?
What are the current treatment guidelines for restless legs syndrome drugs across the seven major markets?
Who are the key companies in the market and what are their market shares?
What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the restless legs syndrome market?
What are the key regulatory events related to the restless legs syndrome market?
What is the structure of clinical trial landscape by status related to the restless legs syndrome market?
What is the structure of clinical trial landscape by phase related to the restless legs syndrome market?
What is the structure of clinical trial landscape by route of administration related to the restless legs syndrome market?
1 PREFACE

2 SCOPE AND METHODOLOGY

2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
  2.3.1 Primary Sources
  2.3.2 Secondary Sources
2.4 Market Estimation
  2.4.1 Bottom-Up Approach
  2.4.2 Top-Down Approach
2.5 Forecasting Methodology

3 EXECUTIVE SUMMARY

4 RESTLESS LEGS SYNDROME - INTRODUCTION

4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence

5 RESTLESS LEGS SYNDROME - DISEASE OVERVIEW

5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment

6 PATIENT JOURNEY

7 RESTLESS LEGS SYNDROME - EPIDEMIOLOGY AND PATIENT POPULATION

7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
  7.2.1 Epidemiology Scenario (2018-2023)
  7.2.2 Epidemiology Forecast (2024-2034)
  7.2.3 Epidemiology by Age (2018-2034)
  7.2.4 Epidemiology by Gender (2018-2034)
  7.2.5 Diagnosed Cases (2018-2034)
  7.2.6 Patient Pool/Treated Cases (2018-2034)
7.3 Epidemiology Scenario - United States
  7.3.1 Epidemiology Scenario (2018-2023)
  7.3.2 Epidemiology Forecast (2024-2034)
  7.3.3 Epidemiology by Age (2018-2034)
  7.3.4 Epidemiology by Gender (2018-2034)
  7.3.5 Diagnosed Cases (2018-2034)
  7.3.6 Patient Pool/Treated Cases (2018-2034)
7.4 Epidemiology Scenario - Germany
  7.4.1 Epidemiology Scenario (2018-2023)
  7.4.2 Epidemiology Forecast (2024-2034)
  7.4.3 Epidemiology by Age (2018-2034)
  7.4.4 Epidemiology by Gender (2018-2034)
  7.4.5 Diagnosed Cases (2018-2034)
  7.4.6 Patient Pool/Treated Cases (2018-2034)
7.5 Epidemiology Scenario - France
  7.5.1 Epidemiology Scenario (2018-2023)
  7.5.2 Epidemiology Forecast (2024-2034)
  7.5.3 Epidemiology by Age (2018-2034)
  7.5.4 Epidemiology by Gender (2018-2034)
  7.5.5 Diagnosed Cases (2018-2034)
  7.5.6 Patient Pool/Treated Cases (2018-2034)
7.6 Epidemiology Scenario - United Kingdom
  7.6.1 Epidemiology Scenario (2018-2023)
  7.6.2 Epidemiology Forecast (2024-2034)
  7.6.3 Epidemiology by Age (2018-2034)
  7.6.4 Epidemiology by Gender (2018-2034)
  7.6.5 Diagnosed Cases (2018-2034)
  7.6.6 Patient Pool/Treated Cases (2018-2034)
7.7 Epidemiology Scenario - Italy
  7.7.1 Epidemiology Scenario (2018-2023)
  7.7.2 Epidemiology Forecast (2024-2034)
  7.7.3 Epidemiology by Age (2018-2034)
  7.7.4 Epidemiology by Gender (2018-2034)
  7.7.5 Diagnosed Cases (2018-2034)
  7.7.6 Patient Pool/Treated Cases (2018-2034)
7.8 Epidemiology Scenario - Spain
  7.8.1 Epidemiology Scenario (2018-2023)
  7.8.2 Epidemiology Forecast (2024-2034)
  7.8.3 Epidemiology by Age (2018-2034)
  7.8.4 Epidemiology by Gender (2018-2034)
  7.8.5 Diagnosed Cases (2018-2034)
  7.8.6 Patient Pool/Treated Cases (2018-2034)
7.9 Epidemiology Scenario - Japan
  7.9.1 Epidemiology Scenario (2018-2023)
  7.9.2 Epidemiology Forecast (2024-2034)
  7.9.3 Epidemiology by Age (2018-2034)
  7.9.4 Epidemiology by Gender (2018-2034)
  7.9.5 Diagnosed Cases (2018-2034)
  7.9.6 Patient Pool/Treated Cases (2018-2034)

8 RESTLESS LEGS SYNDROME - TREATMENT ALGORITHM, GUIDELINES, AND MEDICAL PRACTICES

8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm

9 RESTLESS LEGS SYNDROME - UNMET NEEDS

10 RESTLESS LEGS SYNDROME - KEY ENDPOINTS OF TREATMENT

11 RESTLESS LEGS SYNDROME - MARKETED PRODUCTS

11.1 List of Restless Legs Syndrome Marketed Drugs Across the Top 7 Markets
  11.1.1 Requip (Ropinirole) - GlaxoSmithKline
    11.1.1.1 Drug Overview
    11.1.1.2 Mechanism of Action
    11.1.1.3 Regulatory Status
    11.1.1.4 Clinical Trial Results
    11.1.1.5 Sales Across Major Markets
  11.1.2 Mirapex (Pramipexole) - Boehringer Ingelheim
    11.1.2.1 Drug Overview
    11.1.2.2 Mechanism of Action
    11.1.2.3 Regulatory Status
    11.1.2.4 Clinical Trial Results
    11.1.2.5 Sales Across Major Markets
  11.1.3 Horizant (Gabapentin enacarbil) - Arbor Pharmaceuticals
    11.1.3.1 Drug Overview
    11.1.3.2 Mechanism of Action
    11.1.3.3 Regulatory Status
    11.1.3.4 Clinical Trial Results
    11.1.3.5 Sales Across Major Markets
  11.1.4 Neupro (Rotigotine transdermal) - UCB
    11.1.4.1 Drug Overview
    11.1.4.2 Mechanism of Action
    11.1.4.3 Regulatory Status
    11.1.4.4 Clinical Trial Results
    11.1.4.5 Sales Across Major Markets
Kindly note that the above only represents a partial list of marketed drugs, and the complete list has been provided in the report.

12 RESTLESS LEGS SYNDROME - PIPELINE DRUGS

12.1 List of Restless Legs Syndrome Pipeline Drugs Across the Top 7 Markets
  12.1.1 Injectafer - Vifor
    12.1.1.1 Drug Overview
    12.1.1.2 Mechanism of Action
    12.1.1.3 Clinical Trial Results
    12.1.1.4 Safety and Efficacy
    12.1.1.5 Regulatory Status
Kindly note that the above only represents a partial list of pipeline drugs, and the complete list has been provided in the report.

13. RESTLESS LEGS SYNDROME - ATTRIBUTE ANALYSIS OF KEY MARKETED AND PIPELINE DRUGS

14. RESTLESS LEGS SYNDROME – CLINICAL TRIAL LANDSCAPE

14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events

15 RESTLESS LEGS SYNDROME - MARKET SCENARIO

15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
  15.2.1 Restless Legs Syndrome - Market Size
    15.2.1.1 Market Size (2018-2023)
    15.2.1.2 Market Forecast (2024-2034)
  15.2.2 Restless Legs Syndrome - Market Size by Therapies
    15.2.2.1 Market Size by Therapies (2018-2023)
    15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
  15.3.1 Restless Legs Syndrome - Market Size
    15.3.1.1 Market Size (2018-2023)
    15.3.1.2 Market Forecast (2024-2034)
  15.3.2 Restless Legs Syndrome - Market Size by Therapies
    15.3.2.1 Market Size by Therapies (2018-2023)
    15.3.2.2 Market Forecast by Therapies (2024-2034)
  15.3.3 Restless Legs Syndrome - Access and Reimbursement Overview
15.4 Market Scenario - Germany
  15.4.1 Restless Legs Syndrome - Market Size
    15.4.1.1 Market Size (2018-2023)
    15.4.1.2 Market Forecast (2024-2034)
  15.4.2 Restless Legs Syndrome - Market Size by Therapies
    15.4.2.1 Market Size by Therapies (2018-2023)
    15.4.2.2 Market Forecast by Therapies (2024-2034)
  15.4.3 Restless Legs Syndrome - Access and Reimbursement Overview
15.5 Market Scenario - France
  15.5.1 Restless Legs Syndrome - Market Size
    15.5.1.1 Market Size (2018-2023)
    15.5.1.2 Market Forecast (2024-2034)
  15.5.2 Restless Legs Syndrome - Market Size by Therapies
    15.5.2.1 Market Size by Therapies (2018-2023)
    15.5.2.2 Market Forecast by Therapies (2024-2034)
  15.5.3 Restless Legs Syndrome - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
  15.6.1 Restless Legs Syndrome - Market Size
    15.6.1.1 Market Size (2018-2023)
    15.6.1.2 Market Forecast (2024-2034)
  15.6.2 Restless Legs Syndrome - Market Size by Therapies
    15.6.2.1 Market Size by Therapies (2018-2023)
    15.6.2.2 Market Forecast by Therapies (2024-2034)
  15.6.3 Restless Legs Syndrome - Access and Reimbursement Overview
15.7 Market Scenario - Italy
  15.7.1 Restless Legs Syndrome - Market Size
    15.7.1.1 Market Size (2018-2023)
    15.7.1.2 Market Forecast (2024-2034)
  15.7.2 Restless Legs Syndrome - Market Size by Therapies
    15.7.2.1 Market Size by Therapies (2018-2023)
    15.7.2.2 Market Forecast by Therapies (2024-2034)
  15.7.3 Restless Legs Syndrome - Access and Reimbursement Overview
15.8 Market Scenario - Spain
  15.8.1 Restless Legs Syndrome - Market Size
    15.8.1.1 Market Size (2018-2023)
    15.8.1.2 Market Forecast (2024-2034)
  15.8.2 Restless Legs Syndrome - Market Size by Therapies
    15.8.2.1 Market Size by Therapies (2018-2023)
    15.8.2.2 Market Forecast by Therapies (2024-2034)
  15.8.3 Restless Legs Syndrome - Access and Reimbursement Overview
15.9 Market Scenario - Japan
  15.9.1 Restless Legs Syndrome - Market Size
    15.9.1.1 Market Size (2018-2023)
    15.9.1.2 Market Forecast (2024-2034)
  15.9.2 Restless Legs Syndrome - Market Size by Therapies
    15.9.2.1 Market Size by Therapies (2018-2023)
    15.9.2.2 Market Forecast by Therapies (2024-2034)
  15.9.3 Restless Legs Syndrome - Access and Reimbursement Overview

16 RESTLESS LEGS SYNDROME - RECENT EVENTS AND INPUTS FROM KEY OPINION LEADERS

17 RESTLESS LEGS SYNDROME MARKET - SWOT ANALYSIS

17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats

18 RESTLESS LEGS SYNDROME MARKET – STRATEGIC RECOMMENDATIONS

19 APPENDIX


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