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Recurrent Head and Neck Squamous Cell Carcinoma Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

May 2024 | 128 pages | ID: R6FB20D636D3EN
IMARC Group

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The 7 major recurrent head and neck squamous cell carcinoma markets reached a value of US$ 1.5 Billion in 2023. Looking forward, IMARC Group expects the 7MM to reach US$ 3.5 Billion by 2034, exhibiting a growth rate (CAGR) of 7.87% during 2024-2034.

The recurrent head and neck squamous cell carcinoma market has been comprehensively analyzed in IMARC's new report titled "Recurrent Head and Neck Squamous Cell Carcinoma Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Recurrent head and neck squamous cell carcinoma refers to the return or reappearance of squamous cell carcinoma in the head and neck region after a period of remission or previous treatment. It is a type of cancer that originates from the cells that line the mucosal surfaces of the neck and head, including the mouth, throat, voice box (larynx), and nasal cavity. Some common symptoms associated with this ailment include persistent or worsening pain, swelling, changes in voice, hoarseness, difficulty swallowing, a feeling of obstruction, a chronic sore throat, unexplained weight loss, numbness, weakness, or paralysis of certain facial muscles, frequent infections, etc. The diagnosis of recurrent head and neck squamous cell carcinoma typically involves a combination of medical history evaluation, characteristic findings, and a physical examination. Several imaging techniques, such as computed tomography (CT) scans, magnetic resonance imaging, positron emission tomography (PET) scans, etc., may be used to evaluate the extent and location of the recurrent tumor. If a recurrence is suspected, then a healthcare professional will recommend a tissue biopsy to determine the type and grade of the cancer.

The increasing cases of incomplete surgical resection that fail to completely eradicate all cancerous cells, resulting in the regeneration of residual tissues, are primarily driving the recurrent head and neck squamous cell carcinoma market. In addition to this, the rising incidence of genetic and molecular changes, which affect multiple areas in the mucosal membranes of the upper aerodigestive tract, is also creating a positive outlook for the market. Moreover, the widespread adoption of immune checkpoint inhibitors, such as pembrolizumab and nivolumab, since they work by targeting and blocking the programmed death receptor-1 (PD-1) pathway, thereby modulating immune responses against tumors, is further bolstering the market growth. Apart from this, the escalating application of stereotactic body radiation therapy, which is used to deliver precise high-energy beams while minimizing damage to healthy tissue, is acting as another significant growth-inducing factor. Additionally, the emerging popularity of targeted therapies, like cetuximab and erlotinib, that are designed to inhibit specific molecules or pathways involved in the development of cancer is expected to drive the recurrent head and neck squamous cell carcinoma market during the forecast period.

IMARC Group's new report provides an exhaustive analysis of the recurrent head and neck squamous cell carcinoma market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for recurrent head and neck squamous cell carcinoma and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the recurrent head and neck squamous cell carcinoma market in any manner.

Time Period of the Study

Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034

Countries Covered

United States
Germany
France
United Kingdom
Italy
Spain
Japan

Analysis Covered Across Each Country

Historical, current, and future epidemiology scenario
Historical, current, and future performance of the recurrent head and neck squamous cell carcinoma market
Historical, current, and future performance of various therapeutic categories in the market
Sales of various drugs across the recurrent head and neck squamous cell carcinoma market
Reimbursement scenario in the market
In-market and pipeline drugs
Competitive Landscape:
This report also provides a detailed analysis of the current recurrent head and neck squamous cell carcinoma marketed drugs and late-stage pipeline drugs.

In-Market Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.

Key Questions Answered in this Report:
Market Insights

How has the recurrent head and neck squamous cell carcinoma market performed so far and how will it perform in the coming years?
What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
What was the country-wise size of the recurrent head and neck squamous cell carcinoma market across the seven major markets in 2023 and what will it look like in 2034?
What is the growth rate of the recurrent head and neck squamous cell carcinoma market across the seven major markets and what will be the expected growth over the next ten years?
What are the key unmet needs in the market?

Epidemiology Insights

What is the number of prevalent cases (2018-2034) of recurrent head and neck squamous cell carcinoma across the seven major markets?
What is the number of prevalent cases (2018-2034) of recurrent head and neck squamous cell carcinoma by age across the seven major markets?
What is the number of prevalent cases (2018-2034) of recurrent head and neck squamous cell carcinoma by gender across the seven major markets?
How many patients are diagnosed (2018-2034) with recurrent head and neck squamous cell carcinoma across the seven major markets?
What is the size of the recurrent head and neck squamous cell carcinoma patient pool (2018-2023) across the seven major markets?
What would be the forecasted patient pool (2024-2034) across the seven major markets?
What are the key factors driving the epidemiological trend of recurrent head and neck squamous cell carcinoma?
What will be the growth rate of patients across the seven major markets?

Recurrent Head and Neck Squamous Cell Carcinoma: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

What are the current marketed drugs and what are their market performance?
What are the key pipeline drugs and how are they expected to perform in the coming years?
How safe are the current marketed drugs and what are their efficacies?
How safe are the late-stage pipeline drugs and what are their efficacies?
What are the current treatment guidelines for recurrent head and neck squamous cell carcinoma drugs across the seven major markets?
Who are the key companies in the market and what are their market shares?
What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the recurrent head and neck squamous cell carcinoma market?
What are the key regulatory events related to the recurrent head and neck squamous cell carcinoma market?
What is the structure of clinical trial landscape by status related to the recurrent head and neck squamous cell carcinoma market?
What is the structure of clinical trial landscape by phase related to the recurrent head and neck squamous cell carcinoma market?
What is the structure of clinical trial landscape by route of administration related to the recurrent head and neck squamous cell carcinoma market?
1 PREFACE

2 SCOPE AND METHODOLOGY

2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
  2.3.1 Primary Sources
  2.3.2 Secondary Sources
2.4 Market Estimation
  2.4.1 Bottom-Up Approach
  2.4.2 Top-Down Approach
2.5 Forecasting Methodology

3 EXECUTIVE SUMMARY

4 RECURRENT HEAD AND NECK SQUAMOUS CELL CARCINOMA - INTRODUCTION

4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence

5 RECURRENT HEAD AND NECK SQUAMOUS CELL CARCINOMA - DISEASE OVERVIEW

5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment

6 PATIENT JOURNEY

7 RECURRENT HEAD AND NECK SQUAMOUS CELL CARCINOMA - EPIDEMIOLOGY AND PATIENT POPULATION

7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
  7.2.1 Epidemiology Scenario (2018-2023)
  7.2.2 Epidemiology Forecast (2024-2034)
  7.2.3 Epidemiology by Age (2018-2034)
  7.2.4 Epidemiology by Gender (2018-2034)
  7.2.5 Diagnosed Cases (2018-2034)
  7.2.6 Patient Pool/Treated Cases (2018-2034)
7.3 Epidemiology Scenario - United States
  7.3.1 Epidemiology Scenario (2018-2023)
  7.3.2 Epidemiology Forecast (2024-2034)
  7.3.3 Epidemiology by Age (2018-2034)
  7.3.4 Epidemiology by Gender (2018-2034)
  7.3.5 Diagnosed Cases (2018-2034)
  7.3.6 Patient Pool/Treated Cases (2018-2034)
7.4 Epidemiology Scenario - Germany
  7.4.1 Epidemiology Scenario (2018-2023)
  7.4.2 Epidemiology Forecast (2024-2034)
  7.4.3 Epidemiology by Age (2018-2034)
  7.4.4 Epidemiology by Gender (2018-2034)
  7.4.5 Diagnosed Cases (2018-2034)
  7.4.6 Patient Pool/Treated Cases (2018-2034)
7.5 Epidemiology Scenario - France
  7.5.1 Epidemiology Scenario (2018-2023)
  7.5.2 Epidemiology Forecast (2024-2034)
  7.5.3 Epidemiology by Age (2018-2034)
  7.5.4 Epidemiology by Gender (2018-2034)
  7.5.5 Diagnosed Cases (2018-2034)
  7.5.6 Patient Pool/Treated Cases (2018-2034)
7.6 Epidemiology Scenario - United Kingdom
  7.6.1 Epidemiology Scenario (2018-2023)
  7.6.2 Epidemiology Forecast (2024-2034)
  7.6.3 Epidemiology by Age (2018-2034)
  7.6.4 Epidemiology by Gender (2018-2034)
  7.6.5 Diagnosed Cases (2018-2034)
  7.6.6 Patient Pool/Treated Cases (2018-2034)
7.7 Epidemiology Scenario - Italy
  7.7.1 Epidemiology Scenario (2018-2023)
  7.7.2 Epidemiology Forecast (2024-2034)
  7.7.3 Epidemiology by Age (2018-2034)
  7.7.4 Epidemiology by Gender (2018-2034)
  7.7.5 Diagnosed Cases (2018-2034)
  7.7.6 Patient Pool/Treated Cases (2018-2034)
7.8 Epidemiology Scenario - Spain
  7.8.1 Epidemiology Scenario (2018-2023)
  7.8.2 Epidemiology Forecast (2024-2034)
  7.8.3 Epidemiology by Age (2018-2034)
  7.8.4 Epidemiology by Gender (2018-2034)
  7.8.5 Diagnosed Cases (2018-2034)
  7.8.6 Patient Pool/Treated Cases (2018-2034)
7.9 Epidemiology Scenario - Japan
  7.9.1 Epidemiology Scenario (2018-2023)
  7.9.2 Epidemiology Forecast (2024-2034)
  7.9.3 Epidemiology by Age (2018-2034)
  7.9.4 Epidemiology by Gender (2018-2034)
  7.9.5 Diagnosed Cases (2018-2034)
  7.9.6 Patient Pool/Treated Cases (2018-2034)

8 RECURRENT HEAD AND NECK SQUAMOUS CELL CARCINOMA - TREATMENT ALGORITHM, GUIDELINES, AND MEDICAL PRACTICES

8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm

9 RECURRENT HEAD AND NECK SQUAMOUS CELL CARCINOMA - UNMET NEEDS

10 RECURRENT HEAD AND NECK SQUAMOUS CELL CARCINOMA - KEY ENDPOINTS OF TREATMENT

11 RECURRENT HEAD AND NECK SQUAMOUS CELL CARCINOMA - MARKETED PRODUCTS

11.1 List of Recurrent Head and Neck Squamous Cell Carcinoma Marketed Drugs Across the Top 7 Markets
  11.1.1 Keytruda (Pembrolizumab) - Merck & Co
    11.1.1.1 Drug Overview
    11.1.1.2 Mechanism of Action
    11.1.1.3 Regulatory Status
    11.1.1.4 Clinical Trial Results
    11.1.1.5 Sales Across Major Markets
  11.1.2 Opdivo (Nivolumab) - Bristol-Myers Squibb/Ono Pharmaceuticals
    11.1.2.1 Drug Overview
    11.1.2.2 Mechanism of Action
    11.1.2.3 Regulatory Status
    11.1.2.4 Clinical Trial Results
    11.1.2.5 Sales Across Major Markets
Kindly note that the above only represents a partial list of marketed drugs, and the complete list has been provided in the report.

12 RECURRENT HEAD AND NECK SQUAMOUS CELL CARCINOMA - PIPELINE DRUGS

12.1 List of Recurrent Head and Neck Squamous Cell Carcinoma Pipeline Drugs Across the Top 7 Markets
  12.1.1 BNT113 - BioNTech SE
    12.1.1.1 Drug Overview
    12.1.1.2 Mechanism of Action
    12.1.1.3 Clinical Trial Results
    12.1.1.4 Safety and Efficacy
    12.1.1.5 Regulatory Status
  12.1.2 ASP-1929 - Rakuten Medical
    12.1.2.1 Drug Overview
    12.1.2.2 Mechanism of Action
    12.1.2.3 Clinical Trial Results
    12.1.2.4 Safety and Efficacy
    12.1.2.5 Regulatory Status
  12.1.3 PDS0101 - PDS Biotechnology
    12.1.3.1 Drug Overview
    12.1.3.2 Mechanism of Action
    12.1.3.3 Clinical Trial Results
    12.1.3.4 Safety and Efficacy
    12.1.3.5 Regulatory Status
  12.1.4 CUE-101 - Cue Biopharma
    12.1.4.1 Drug Overview
    12.1.4.2 Mechanism of Action
    12.1.4.3 Clinical Trial Results
    12.1.4.4 Safety and Efficacy
    12.1.4.5 Regulatory Status
Kindly note that the above only represents a partial list of pipeline drugs, and the complete list has been provided in the report.

13. RECURRENT HEAD AND NECK SQUAMOUS CELL CARCINOMA - ATTRIBUTE ANALYSIS OF KEY MARKETED AND PIPELINE DRUGS

14. RECURRENT HEAD AND NECK SQUAMOUS CELL CARCINOMA – CLINICAL TRIAL LANDSCAPE

14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events

15 RECURRENT HEAD AND NECK SQUAMOUS CELL CARCINOMA - MARKET SCENARIO

15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
  15.2.1 Recurrent Head and Neck Squamous Cell Carcinoma - Market Size
    15.2.1.1 Market Size (2018-2023)
    15.2.1.2 Market Forecast (2024-2034)
  15.2.2 Recurrent Head and Neck Squamous Cell Carcinoma - Market Size by Therapies
    15.2.2.1 Market Size by Therapies (2018-2023)
    15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
  15.3.1 Recurrent Head and Neck Squamous Cell Carcinoma - Market Size
    15.3.1.1 Market Size (2018-2023)
    15.3.1.2 Market Forecast (2024-2034)
  15.3.2 Recurrent Head and Neck Squamous Cell Carcinoma - Market Size by Therapies
    15.3.2.1 Market Size by Therapies (2018-2023)
    15.3.2.2 Market Forecast by Therapies (2024-2034)
  15.3.3 Recurrent Head and Neck Squamous Cell Carcinoma - Access and Reimbursement Overview
15.4 Market Scenario - Germany
  15.4.1 Recurrent Head and Neck Squamous Cell Carcinoma - Market Size
    15.4.1.1 Market Size (2018-2023)
    15.4.1.2 Market Forecast (2024-2034)
  15.4.2 Recurrent Head and Neck Squamous Cell Carcinoma - Market Size by Therapies
    15.4.2.1 Market Size by Therapies (2018-2023)
    15.4.2.2 Market Forecast by Therapies (2024-2034)
  15.4.3 Recurrent Head and Neck Squamous Cell Carcinoma - Access and Reimbursement Overview
15.5 Market Scenario - France
  15.5.1 Recurrent Head and Neck Squamous Cell Carcinoma - Market Size
    15.5.1.1 Market Size (2018-2023)
    15.5.1.2 Market Forecast (2024-2034)
  15.5.2 Recurrent Head and Neck Squamous Cell Carcinoma - Market Size by Therapies
    15.5.2.1 Market Size by Therapies (2018-2023)
    15.5.2.2 Market Forecast by Therapies (2024-2034)
  15.5.3 Recurrent Head and Neck Squamous Cell Carcinoma - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
  15.6.1 Recurrent Head and Neck Squamous Cell Carcinoma - Market Size
    15.6.1.1 Market Size (2018-2023)
    15.6.1.2 Market Forecast (2024-2034)
  15.6.2 Recurrent Head and Neck Squamous Cell Carcinoma - Market Size by Therapies
    15.6.2.1 Market Size by Therapies (2018-2023)
    15.6.2.2 Market Forecast by Therapies (2024-2034)
  15.6.3 Recurrent Head and Neck Squamous Cell Carcinoma - Access and Reimbursement Overview
15.7 Market Scenario - Italy
  15.7.1 Recurrent Head and Neck Squamous Cell Carcinoma - Market Size
    15.7.1.1 Market Size (2018-2023)
    15.7.1.2 Market Forecast (2024-2034)
  15.7.2 Recurrent Head and Neck Squamous Cell Carcinoma - Market Size by Therapies
    15.7.2.1 Market Size by Therapies (2018-2023)
    15.7.2.2 Market Forecast by Therapies (2024-2034)
  15.7.3 Recurrent Head and Neck Squamous Cell Carcinoma - Access and Reimbursement Overview
15.8 Market Scenario - Spain
  15.8.1 Recurrent Head and Neck Squamous Cell Carcinoma - Market Size
    15.8.1.1 Market Size (2018-2023)
    15.8.1.2 Market Forecast (2024-2034)
  15.8.2 Recurrent Head and Neck Squamous Cell Carcinoma - Market Size by Therapies
    15.8.2.1 Market Size by Therapies (2018-2023)
    15.8.2.2 Market Forecast by Therapies (2024-2034)
  15.8.3 Recurrent Head and Neck Squamous Cell Carcinoma - Access and Reimbursement Overview
15.9 Market Scenario - Japan
  15.9.1 Recurrent Head and Neck Squamous Cell Carcinoma - Market Size
    15.9.1.1 Market Size (2018-2023)
    15.9.1.2 Market Forecast (2024-2034)
  15.9.2 Recurrent Head and Neck Squamous Cell Carcinoma - Market Size by Therapies
    15.9.2.1 Market Size by Therapies (2018-2023)
    15.9.2.2 Market Forecast by Therapies (2024-2034)
  15.9.3 Recurrent Head and Neck Squamous Cell Carcinoma - Access and Reimbursement Overview

16 RECURRENT HEAD AND NECK SQUAMOUS CELL CARCINOMA - RECENT EVENTS AND INPUTS FROM KEY OPINION LEADERS

17 RECURRENT HEAD AND NECK SQUAMOUS CELL CARCINOMA MARKET - SWOT ANALYSIS

17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats

18 RECURRENT HEAD AND NECK SQUAMOUS CELL CARCINOMA MARKET – STRATEGIC RECOMMENDATIONS

19 APPENDIX


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