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Recurrent Glioblastoma Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

May 2024 | 130 pages | ID: R5E9E40B6AB6EN
IMARC Group

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The 7 major recurrent glioblastoma markets are expected to exhibit a CAGR of 5.85% during 2024-2034.

The recurrent glioblastoma market has been comprehensively analyzed in IMARC's new report titled "Recurrent Glioblastoma Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Recurrent glioblastoma refers to the return or progression of glioblastoma multiforme (GBM), which is the most aggressive and common form of malignant brain tumor. It is classified as a grade IV astrocytoma and typically exhibits rapid growth and invasive behavior within the brain. The disease can occur at the original site of the tumor or in nearby areas of the brain. It can also manifest as multiple lesions in different regions of the central nervous system. The common symptoms of the ailment include persistent or worsening headaches, convulsions, loss of consciousness, abnormal sensations and movements, cognitive decline, memory problems, difficulty concentrating, changes in personality, numbness, blurred vision, hearing loss, generalized weakness, etc. The diagnosis of recurrent glioblastoma involves a combination of imaging studies, clinical evaluation, and various additional procedures. The healthcare provider will initially perform a physical examination to assess the neurological function and overall health of the patient. Several diagnostic techniques, such as magnetic resonance imaging and positron emission tomography scans, are also utilized to determine the extent and location of the disease.

The increasing incidence of incomplete surgical resection, causing the small cancerous cells to regrow and multiply, is primarily driving the recurrent glioblastoma market. In addition to this, the rising prevalence of genetic mutations and alterations that lead to treatment resistance as well as contribute to the aggressive nature of tumors is also creating a positive outlook for the market. Moreover, the widespread adoption of molecularly targeted drugs, like bevacizumab, since they block specific signaling pathways involved in the proliferation of unhealthy tissues and the formation of new blood vessels, is further bolstering the market growth. Apart from this, the escalating application of tumor treating field therapy, which uses a device to emit alternating electric fields to disrupt cell division and limit disease progression, is acting as another significant growth-inducing factor. Additionally, the emerging popularity of gene therapy for the treatment of the ailment, owing to its several associated benefits, such as enhanced sensitivity to regimens, increased tumor suppression, and long-term therapeutic effects, is expected to drive the recurrent glioblastoma market during the forecast period.

IMARC Group's new report provides an exhaustive analysis of the recurrent glioblastoma market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for recurrent glioblastoma and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the recurrent glioblastoma market in any manner.

Time Period of the Study

Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034

Countries Covered

United States
Germany
France
United Kingdom
Italy
Spain
Japan

Analysis Covered Across Each Country

Historical, current, and future epidemiology scenario
Historical, current, and future performance of the recurrent glioblastoma market
Historical, current, and future performance of various therapeutic categories in the market
Sales of various drugs across the recurrent glioblastoma market
Reimbursement scenario in the market
In-market and pipeline drugs
Competitive Landscape:
This report also provides a detailed analysis of the current recurrent glioblastoma marketed drugs and late-stage pipeline drugs.

In-Market Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Regulatory Status

*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.

Key Questions Answered in this Report:
Market Insights

How has the recurrent glioblastoma market performed so far and how will it perform in the coming years?
What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
What was the country-wise size of the recurrent glioblastoma market across the seven major markets in 2023 and what will it look like in 2034?
What is the growth rate of the recurrent glioblastoma market across the seven major markets and what will be the expected growth over the next ten years?
What are the key unmet needs in the market?

Epidemiology Insights

What is the number of prevalent cases (2018-2034) of recurrent glioblastoma across the seven major markets?
What is the number of prevalent cases (2018-2034) of recurrent glioblastoma by age across the seven major markets?
What is the number of prevalent cases (2018-2034) of recurrent glioblastoma by gender across the seven major markets?
What is the number of prevalent cases (2018-2034) of recurrent glioblastoma by type across the seven major markets?
How many patients are diagnosed (2018-2034) with recurrent glioblastoma across the seven major markets?
What is the size of the recurrent glioblastoma patient pool (2018-2023) across the seven major markets?
What would be the forecasted patient pool (2024-2034) across the seven major markets?
What are the key factors driving the epidemiological trend of recurrent glioblastoma?
What will be the growth rate of patients across the seven major markets?

Recurrent Glioblastoma: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

What are the current marketed drugs and what are their market performance?
What are the key pipeline drugs and how are they expected to perform in the coming years?
How safe are the current marketed drugs and what are their efficacies?
How safe are the late-stage pipeline drugs and what are their efficacies?
What are the current treatment guidelines for recurrent glioblastoma drugs across the seven major markets?
Who are the key companies in the market and what are their market shares?
What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the recurrent glioblastoma market?
What are the key regulatory events related to the recurrent glioblastoma market?
What is the structure of clinical trial landscape by status related to the recurrent glioblastoma market?
What is the structure of clinical trial landscape by phase related to the recurrent glioblastoma market?
What is the structure of clinical trial landscape by route of administration related to the recurrent glioblastoma market?
1 PREFACE

2 SCOPE AND METHODOLOGY

2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
  2.3.1 Primary Sources
  2.3.2 Secondary Sources
2.4 Market Estimation
  2.4.1 Bottom-Up Approach
  2.4.2 Top-Down Approach
2.5 Forecasting Methodology

3 EXECUTIVE SUMMARY

4 RECURRENT GLIOBLASTOMA - INTRODUCTION

4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence

5 RECURRENT GLIOBLASTOMA - DISEASE OVERVIEW

5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment

6 PATIENT JOURNEY

7 RECURRENT GLIOBLASTOMA - EPIDEMIOLOGY AND PATIENT POPULATION

7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
  7.2.1 Epidemiology Scenario (2018-2023)
  7.2.2 Epidemiology Forecast (2024-2034)
  7.2.3 Epidemiology by Age (?2018-2034?)
  7.2.4 Epidemiology by Gender (?2018-2034?)
  7.2.5 Epidemiology by Type (?2018-2034?)
  7.2.6 Diagnosed Cases (?2018-2034?)
  7.2.7 Patient Pool/Treated Cases (?2018-2034?)
7.3 Epidemiology Scenario - United States
  7.3.1 Epidemiology Scenario (2018-2023)
  7.3.2 Epidemiology Forecast (2024-2034)
  7.3.3 Epidemiology by Age (?2018-2034?)
  7.3.4 Epidemiology by Gender (?2018-2034?)
  7.3.5 Epidemiology by Type (?2018-2034?)
  7.3.6 Diagnosed Cases (?2018-2034?)
  7.3.7 Patient Pool/Treated Cases (?2018-2034?)
7.4 Epidemiology Scenario - Germany
  7.4.1 Epidemiology Scenario (2018-2023)
  7.4.2 Epidemiology Forecast (2024-2034)
  7.4.3 Epidemiology by Age (?2018-2034?)
  7.4.4 Epidemiology by Gender (?2018-2034?)
  7.4.5 Epidemiology by Type (?2018-2034?)
  7.4.6 Diagnosed Cases (?2018-2034?)
  7.4.7 Patient Pool/Treated Cases (?2018-2034?)
7.5 Epidemiology Scenario - France
  7.5.1 Epidemiology Scenario (2018-2023)
  7.5.2 Epidemiology Forecast (2024-2034)
  7.5.3 Epidemiology by Age (?2018-2034?)
  7.5.4 Epidemiology by Gender (?2018-2034?)
  7.5.5 Epidemiology by Type (?2018-2034?)
  7.5.6 Diagnosed Cases (?2018-2034?)
  7.5.7 Patient Pool/Treated Cases (?2018-2034?)
7.6 Epidemiology Scenario - United Kingdom
  7.6.1 Epidemiology Scenario (2018-2023)
  7.6.2 Epidemiology Forecast (2024-2034)
  7.6.3 Epidemiology by Age (?2018-2034?)
  7.6.4 Epidemiology by Gender (?2018-2034?)
  7.6.5 Epidemiology by Type (?2018-2034?)
  7.6.6 Diagnosed Cases (?2018-2034?)
  7.6.7 Patient Pool/Treated Cases (?2018-2034?)
7.7 Epidemiology Scenario - Italy
  7.7.1 Epidemiology Scenario (2018-2023)
  7.7.2 Epidemiology Forecast (2024-2034)
  7.7.3 Epidemiology by Age (?2018-2034?)
  7.7.4 Epidemiology by Gender (?2018-2034?)
  7.7.5 Epidemiology by Type (?2018-2034?)
  7.7.6 Diagnosed Cases (?2018-2034?)
  7.7.7 Patient Pool/Treated Cases (?2018-2034?)
7.8 Epidemiology Scenario - Spain
  7.8.1 Epidemiology Scenario (2018-2023)
  7.8.2 Epidemiology Forecast (2024-2034)
  7.8.3 Epidemiology by Age (?2018-2034?)
  7.8.4 Epidemiology by Gender (?2018-2034?)
  7.8.5 Epidemiology by Type (?2018-2034?)
  7.8.6 Diagnosed Cases (?2018-2034?)
  7.8.7 Patient Pool/Treated Cases (?2018-2034?)
7.9 Epidemiology Scenario - Japan
  7.9.1 Epidemiology Scenario (2018-2023)
  7.9.2 Epidemiology Forecast (2024-2034)
  7.9.3 Epidemiology by Age (?2018-2034?)
  7.9.4 Epidemiology by Gender (?2018-2034?)
  7.9.5 Epidemiology by Type (?2018-2034?)
  7.9.6 Diagnosed Cases (?2018-2034?)
  7.9.7 Patient Pool/Treated Cases (?2018-2034?)

8 RECURRENT GLIOBLASTOMA - TREATMENT ALGORITHM, GUIDELINES, AND MEDICAL PRACTICES

8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm

9 RECURRENT GLIOBLASTOMA - UNMET NEEDS

10 RECURRENT GLIOBLASTOMA - KEY ENDPOINTS OF TREATMENT

11 RECURRENT GLIOBLASTOMA - MARKETED PRODUCTS

11.1 List of Recurrent Glioblastoma Marketed Drugs Across the Top 7 Markets
  11.1.1 Gliadel Wafer (Carmustine polifeprosan 20 wafer) - Arbor Pharmaceuticals/ Eisai
    11.1.1.1 Drug Overview
    11.1.1.2 Mechanism of Action
    11.1.1.3 Regulatory Status
    11.1.1.4 Clinical Trial Results
    11.1.1.5 Sales Across Major Markets
Kindly note that the above only represents a partial list of marketed drugs, and the complete list has been provided in the report.

12 RECURRENT GLIOBLASTOMA - PIPELINE DRUGS

12.1 List of Recurrent Glioblastoma Pipeline Drugs Across the Top 7 Markets
  12.1.1 ACT 001 - Accendatech
    12.1.1.1 Drug Overview
    12.1.1.2 Mechanism of Action
    12.1.1.3 Clinical Trial Results
    12.1.1.4 Safety and Efficacy
    12.1.1.5 Regulatory Status
  12.1.2 MTX 110 - Biodexa Pharmaceuticals
    12.1.2.1 Drug Overview
    12.1.2.2 Mechanism of Action
    12.1.2.3 Clinical Trial Results
    12.1.2.4 Safety and Efficacy
    12.1.2.5 Regulatory Status
  12.1.3 TTAC-0001 - PharmAbcine
    12.1.3.1 Drug Overview
    12.1.3.2 Mechanism of Action
    12.1.3.3 Clinical Trial Results
    12.1.3.4 Safety and Efficacy
    12.1.3.5 Regulatory Status
  12.1.4 VXM 01 - Vaximm GmbH
    12.1.4.1 Drug Overview
    12.1.4.2 Mechanism of Action
    12.1.4.3 Clinical Trial Results
    12.1.4.4 Safety and Efficacy
    12.1.4.5 Regulatory Status
  12.1.5 MN-166 - MediciNova
    12.1.5.1 Drug Overview
    12.1.5.2 Mechanism of Action
    12.1.5.3 Clinical Trial Results
    12.1.5.4 Safety and Efficacy
    12.1.5.5 Regulatory Status
Kindly note that the above only represents a partial list of pipeline drugs, and the complete list has been provided in the report.

13. RECURRENT GLIOBLASTOMA - ATTRIBUTE ANALYSIS OF KEY MARKETED AND PIPELINE DRUGS

14. RECURRENT GLIOBLASTOMA – CLINICAL TRIAL LANDSCAPE

14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events

15 RECURRENT GLIOBLASTOMA - MARKET SCENARIO

15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
  15.2.1 Recurrent Glioblastoma - Market Size
    15.2.1.1 Market Size (2018-2023)
    15.2.1.2 Market Forecast (2024-2034)
  15.2.2 Recurrent Glioblastoma - Market Size by Therapies
    15.2.2.1 Market Size by Therapies (2018-2023)
    15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
  15.3.1 Recurrent Glioblastoma - Market Size
    15.3.1.1 Market Size (2018-2023)
    15.3.1.2 Market Forecast (2024-2034)
  15.3.2 Recurrent Glioblastoma - Market Size by Therapies
    15.3.2.1 Market Size by Therapies (2018-2023)
    15.3.2.2 Market Forecast by Therapies (2024-2034)
  15.3.3 Recurrent Glioblastoma - Access and Reimbursement Overview
15.4 Market Scenario - Germany
  15.4.1 Recurrent Glioblastoma - Market Size
    15.4.1.1 Market Size (2018-2023)
    15.4.1.2 Market Forecast (2024-2034)
  15.4.2 Recurrent Glioblastoma - Market Size by Therapies
    15.4.2.1 Market Size by Therapies (2018-2023)
    15.4.2.2 Market Forecast by Therapies (2024-2034)
  15.4.3 Recurrent Glioblastoma - Access and Reimbursement Overview
15.5 Market Scenario - France
  15.5.1 Recurrent Glioblastoma - Market Size
    15.5.1.1 Market Size (2018-2023)
    15.5.1.2 Market Forecast (2024-2034)
  15.5.2 Recurrent Glioblastoma - Market Size by Therapies
    15.5.2.1 Market Size by Therapies (2018-2023)
    15.5.2.2 Market Forecast by Therapies (2024-2034)
  15.5.3 Recurrent Glioblastoma - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
  15.6.1 Recurrent Glioblastoma - Market Size
    15.6.1.1 Market Size (2018-2023)
    15.6.1.2 Market Forecast (2024-2034)
  15.6.2 Recurrent Glioblastoma - Market Size by Therapies
    15.6.2.1 Market Size by Therapies (2018-2023)
    15.6.2.2 Market Forecast by Therapies (2024-2034)
  15.6.3 Recurrent Glioblastoma - Access and Reimbursement Overview
15.7 Market Scenario - Italy
  15.7.1 Recurrent Glioblastoma - Market Size
    15.7.1.1 Market Size (2018-2023)
    15.7.1.2 Market Forecast (2024-2034)
  15.7.2 Recurrent Glioblastoma - Market Size by Therapies
    15.7.2.1 Market Size by Therapies (2018-2023)
    15.7.2.2 Market Forecast by Therapies (2024-2034)
  15.7.3 Recurrent Glioblastoma - Access and Reimbursement Overview
15.8 Market Scenario - Spain
  15.8.1 Recurrent Glioblastoma - Market Size
    15.8.1.1 Market Size (2018-2023)
    15.8.1.2 Market Forecast (2024-2034)
  15.8.2 Recurrent Glioblastoma - Market Size by Therapies
    15.8.2.1 Market Size by Therapies (2018-2023)
    15.8.2.2 Market Forecast by Therapies (2024-2034)
  15.8.3 Recurrent Glioblastoma - Access and Reimbursement Overview
15.9 Market Scenario - Japan
  15.9.1 Recurrent Glioblastoma - Market Size
    15.9.1.1 Market Size (2018-2023)
    15.9.1.2 Market Forecast (2024-2034)
  15.9.2 Recurrent Glioblastoma - Market Size by Therapies
    15.9.2.1 Market Size by Therapies (2018-2023)
    15.9.2.2 Market Forecast by Therapies (2024-2034)
  15.9.3 Recurrent Glioblastoma - Access and Reimbursement Overview

16 RECURRENT GLIOBLASTOMA - RECENT EVENTS AND INPUTS FROM KEY OPINION LEADERS

17 RECURRENT GLIOBLASTOMA MARKET - SWOT ANALYSIS

17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats

18 RECURRENT GLIOBLASTOMA MARKET – STRATEGIC RECOMMENDATIONS

19 APPENDIX


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