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Paroxysmal Nocturnal Hemoglobinuria: Epidemiology Forecasting Intelligence

February 2019 | 50 pages | ID: PEA2DB96881EN
CmaxInsight Market Intelligence

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CmaxInsight’s “Paroxysmal Nocturnal Hemoglobinuria-Epidemiology Forecasting Intelligence” report provides a comprehensive analysis of the Paroxysmal Nocturnal Hemoglobinuria epidemiology, providing the historical, current, and forecasted data for the United States, European Union 5 (EU5- Germany, Spain, Italy, France and United Kingdom) and Japan during the period from 2018-2028.

Our epidemiology services include:
  • Incidence and prevalence
  • Diagnosis rate, treatment rate and mortality patterns
  • Epidemiology-based forecasting and disease trends
  • Size of different patient segments in a disease area
  • Population based: disease occurrence, co-morbidities and treatment patterns
  • Geographic - Regional - Ethnic differences
Along with the epidemiological data, the report also includes:
  • Disease overview, causes, symptoms, classification, risk factor, pathophysiology, diagnosis and treatment
  • Patient treatment journey
  • Treatment algorithm and guidelines
  • Assesses the disease risk and burden
  • Highlights the unmet needs
  • Market driver and barrier
  • Growth opportunities and market trend analysis
Methodology
  • This report is built using data and information sourced from proprietary databases, primary and secondary research and in-house Epidemiology Forecast model analysis by a team of industry experts.
  • To generate accurate patient population estimates, utilizes a combination of several world class sources that deliver the most up to date information from patient registries, clinical trials and epidemiology studies.
  • All of the sources used to generate the data and analysis have been identified in the report.
Note: Systematic review of the epidemiological literature is also provided for full transparency into research and methods. This report can be delivered to the clients within 4-5 business days.
1. REPORT INTRODUCTION

2. PAROXYSMAL NOCTURNAL HEMOGLOBINURIA EPIDEMIOLOGY OVERVIEW AT A GLANCE

3. MARKET SHARE DISTRIBUTION OF PAROXYSMAL NOCTURNAL HEMOGLOBINURIA

4. DISEASE BACKGROUND AND OVERVIEW: PAROXYSMAL NOCTURNAL HEMOGLOBINURIA

4.1. Introduction
4.2. Signs and Symptoms
4.3. Etiology
4.4. Risk Factors
4.5. Pathophysiology
4.6. Diagnostic Landscape
  4.6.1. Diagnostic Practices
  4.6.2. Diagnostic Criteria
  4.6.3. Diagnostic Recommendations
4.7. Treatment Landscape
  4.7.1. Current Treatment Practices
  4.7.2. Treatment Algorithm
  4.7.3. Treatment Recommendations

5. PAROXYSMAL NOCTURNAL HEMOGLOBINURIA EPIDEMIOLOGY

5.1. Key Findings
5.2. Assumptions & Rationale
5.3. 7MM Epidemiology

6. EPIDEMIOLOGY OF PAROXYSMAL NOCTURNAL HEMOGLOBINURIA BY COUNTRIES

7. UNITED STATES

7.1. Assumptions and Rationale
7.2. Prevalent/Incident Cases of Paroxysmal Nocturnal Hemoglobinuria
7.3. Sub-Type Specific cases of Paroxysmal Nocturnal Hemoglobinuria*
7.4. Sex- Specific Cases of Paroxysmal Nocturnal Hemoglobinuria*
7.5. Diagnosed Cases of Paroxysmal Nocturnal Hemoglobinuria
7.6. Treated Cases of Paroxysmal Nocturnal Hemoglobinuria

8. EU5

8.1. Germany
  8.1.1. Assumptions and Rationale
  8.1.2. Prevalent/Incident Cases of Paroxysmal Nocturnal Hemoglobinuria
  8.1.3. Sub-Type Specific cases of Paroxysmal Nocturnal Hemoglobinuria*
  8.1.4. Sex- Specific Cases of Paroxysmal Nocturnal Hemoglobinuria*
  8.1.5. Diagnosed Cases of Paroxysmal Nocturnal Hemoglobinuria
  8.1.6. Treated Cases of Paroxysmal Nocturnal Hemoglobinuria
8.2. France
  8.2.1. Assumptions and Rationale
  8.2.2. Prevalent/Incident Cases of Paroxysmal Nocturnal Hemoglobinuria
  8.2.3. Sub-Type Specific cases of Paroxysmal Nocturnal Hemoglobinuria*
  8.2.4. Sex- Specific Cases of Paroxysmal Nocturnal Hemoglobinuria*
  8.2.5. Diagnosed Cases of Paroxysmal Nocturnal Hemoglobinuria
  8.2.6. Treated Cases of Paroxysmal Nocturnal Hemoglobinuria
8.3. United Kingdom
  8.3.1. Assumptions and Rationale
  8.3.2. Prevalent/Incident Cases of Paroxysmal Nocturnal Hemoglobinuria
  8.3.3. Sub-Type Specific cases of Paroxysmal Nocturnal Hemoglobinuria*
  8.3.4. Sex- Specific Cases of Paroxysmal Nocturnal Hemoglobinuria*
  8.3.5. Diagnosed Cases of Paroxysmal Nocturnal Hemoglobinuria
  8.3.6. Treated Cases of Paroxysmal Nocturnal Hemoglobinuria
8.4. Spain
  8.4.1. Assumptions and Rationale
  8.4.2. Prevalent/Incident Cases of Paroxysmal Nocturnal Hemoglobinuria
  8.4.3. Sub-Type Specific cases of Paroxysmal Nocturnal Hemoglobinuria*
  8.4.4. Sex- Specific Cases of Paroxysmal Nocturnal Hemoglobinuria*
  8.4.5. Diagnosed Cases of Paroxysmal Nocturnal Hemoglobinuria
  8.4.6. Treated Cases of Paroxysmal Nocturnal Hemoglobinuria
8.5. Italy
  8.5.1. Assumptions and Rationale
  8.5.2. Prevalent/Incident Cases of Paroxysmal Nocturnal Hemoglobinuria
  8.5.3. Sub-Type Specific cases of Paroxysmal Nocturnal Hemoglobinuria*
  8.5.4. Sex- Specific Cases of Paroxysmal Nocturnal Hemoglobinuria*
  8.5.5. Diagnosed Cases of Paroxysmal Nocturnal Hemoglobinuria
  8.5.6. Treated Cases of Paroxysmal Nocturnal Hemoglobinuria

9. JAPAN

9.1. Assumptions and Rationale
9.2. Prevalent/Incident Cases of Paroxysmal Nocturnal Hemoglobinuria
9.3. Sub-Type Specific cases of Paroxysmal Nocturnal Hemoglobinuria*
9.4. Sex- Specific Cases of Paroxysmal Nocturnal Hemoglobinuria*
9.5. Diagnosed Cases of Paroxysmal Nocturnal Hemoglobinuria
9.6. Treated Cases of Paroxysmal Nocturnal Hemoglobinuria

10. UNMET NEEDS

Appendix
Report Methodology
Sources Used
Disclaimer
About CmaxInsight
*Indication Specific
Note: Certain sections of the table of contents would vary according to the availability of information.

LIST OF TABLES

Table 1: Total Prevalent/Incident Cases of the Paroxysmal Nocturnal Hemoglobinuria in 7MM
Table 2: Total Prevalent/Incident Cases of the Paroxysmal Nocturnal Hemoglobinuria in 7MM by Countries
Table 3: Prevalent/Incident Cases of the Paroxysmal Nocturnal Hemoglobinuria in United States
Table 4: Sub-Type Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in United States*
Table 5: Sex- Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in United States*
Table 6: Diagnosed Cases of the Paroxysmal Nocturnal Hemoglobinuria in United States
Table 7: Treated Cases of the Paroxysmal Nocturnal Hemoglobinuria in United States
Table 8: Prevalent/Incident Cases of the Paroxysmal Nocturnal Hemoglobinuria in Germany
Table 9: Sub-Type Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in Germany*
Table 10: Sex- Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in Germany*
Table 11: Diagnosed Cases of the Paroxysmal Nocturnal Hemoglobinuria in Germany
Table 12: Treated Cases of the Paroxysmal Nocturnal Hemoglobinuria in Germany
Table 13: Prevalent/Incident Cases of the Paroxysmal Nocturnal Hemoglobinuria in France
Table 14: Sub-Type Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in France*
Table 15: Sex- Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in France*
Table 16: Diagnosed Cases of the Paroxysmal Nocturnal Hemoglobinuria in France
Table 17: Treated Cases of the Paroxysmal Nocturnal Hemoglobinuria in France
Table 18: Prevalent/Incident Cases of the Paroxysmal Nocturnal Hemoglobinuria in Italy
Table 19: Sub-Type Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in Italy*
Table 20: Sex- Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in Italy*
Table 21: Diagnosed Cases of the Paroxysmal Nocturnal Hemoglobinuria in Italy
Table 22: Treated Cases of the Paroxysmal Nocturnal Hemoglobinuria in Italy
Table 23: Prevalent/Incident Cases of the Paroxysmal Nocturnal Hemoglobinuria in Spain
Table 24: Sub-Type Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in Spain*
Table 25: Sex- Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in Spain*
Table 26: Diagnosed Cases of the Paroxysmal Nocturnal Hemoglobinuria in Spain
Table 27: Treated Cases of the Paroxysmal Nocturnal Hemoglobinuria in Spain
Table 28: Prevalent/Incident Cases of the Paroxysmal Nocturnal Hemoglobinuria in UK
Table 29: Sub-Type Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in UK*
Table 30: Sex- Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in UK*
Table 31: Diagnosed Cases of the Paroxysmal Nocturnal Hemoglobinuria in UK
Table 32: Treated Cases of the Paroxysmal Nocturnal Hemoglobinuria in UK
Table 33: Prevalent/Incident Cases of the Paroxysmal Nocturnal Hemoglobinuria in Japan
Table 34: Sub-Type Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in Japan*
Table 35: Sex- Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in Japan*
Table 36: Diagnosed Cases of the Paroxysmal Nocturnal Hemoglobinuria in Japan
Table 37: Treated Cases of the Paroxysmal Nocturnal Hemoglobinuria in Japan

*Indication Specific

LIST OF FIGURES

Figure 1: Total Prevalent/Incident Cases of the Paroxysmal Nocturnal Hemoglobinuria in 7MM
Figure 2: Total Prevalent/Incident Cases of the Paroxysmal Nocturnal Hemoglobinuria in 7MM by Countries
Figure 3: Prevalent/Incident Cases of the Paroxysmal Nocturnal Hemoglobinuria in United States
Figure 4: Sub-Type Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in United States*
Figure 5: Sex- Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in United States*
Figure 6: Diagnosed Cases of the Paroxysmal Nocturnal Hemoglobinuria in United States
Figure 7: Treated Cases of the Paroxysmal Nocturnal Hemoglobinuria in United States
Figure 8: Prevalent/Incident Cases of the Paroxysmal Nocturnal Hemoglobinuria in Germany
Figure 9: Sub-Type Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in Germany*
Figure 10: Sex- Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in Germany*
Figure 11: Diagnosed Cases of the Paroxysmal Nocturnal Hemoglobinuria in Germany
Figure 12: Treated Cases of the Paroxysmal Nocturnal Hemoglobinuria in Germany
Figure 13: Prevalent/Incident Cases of the Paroxysmal Nocturnal Hemoglobinuria in France
Figure 14: Sub-Type Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in France*
Figure 15: Sex- Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in France*
Figure 16: Diagnosed Cases of the Paroxysmal Nocturnal Hemoglobinuria in France
Figure 17: Treated Cases of the Paroxysmal Nocturnal Hemoglobinuria in United France
Figure 18: Prevalent/Incident Cases of the Paroxysmal Nocturnal Hemoglobinuria in Italy
Figure 19: Sub-Type Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in Italy*
Figure 20: Sex- Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in Italy*
Figure 21: Diagnosed Cases of the Paroxysmal Nocturnal Hemoglobinuria in Italy
Figure 22: Treated Cases of the Paroxysmal Nocturnal Hemoglobinuria in Italy
Figure 23: Prevalent/Incident Cases of the Paroxysmal Nocturnal Hemoglobinuria in Spain
Figure 24: Sub-Type Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in Spain*
Figure 25: Sex- Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in Spain*
Figure 26: Diagnosed Cases of the Paroxysmal Nocturnal Hemoglobinuria in Spain
Figure 27: Treated Cases of the Paroxysmal Nocturnal Hemoglobinuria in Spain
Figure 28: Prevalent/Incident Cases of the Paroxysmal Nocturnal Hemoglobinuria in UK
Figure 29: Sub-Type Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in UK*
Figure 30: Sex- Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in UK*
Figure 31: Diagnosed Cases of the Paroxysmal Nocturnal Hemoglobinuria in UK
Figure 32: Treated Cases of the Paroxysmal Nocturnal Hemoglobinuria in UK
Figure 33: Prevalent/Incident Cases of the Paroxysmal Nocturnal Hemoglobinuria in Japan
Figure 34: Sub-Type Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in Japan*
Figure 35: Sex- Specific Cases of the Paroxysmal Nocturnal Hemoglobinuria in Japan*
Figure 36: Diagnosed Cases of the Paroxysmal Nocturnal Hemoglobinuria in Japan
Figure 37: Treated Cases of the Paroxysmal Nocturnal Hemoglobinuria in Japan

*Indication Specific


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