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Non-Injectable Insulin Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2018-2028 Segmented By Product (Pills, Sprays, and Others), By Distribution Channel (Hospital Pharmacies, and Online Pharmacies, Drug Stores), By Region, By Competition

October 2023 | 181 pages | ID: N5C40BE8BEAEEN
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The Global Non-Injectable Insulin Market achieved a valuation of USD 2.69 Billion in 2022 and is poised for substantial growth throughout the forecast period, projected to maintain a robust Compound Annual Growth Rate (CAGR) of 9.10% and is expected to reach USD 4.51 Billion 2028. This dynamic market segment encompasses a diverse array of insulin formulations tailored for administration without the need for injections. These innovative alternatives cater to individuals coping with diabetes, addressing challenges associated with traditional injection methods and allergic reactions to injections. Non-injectable insulin options span oral, inhalable, patches, and emerging delivery methods.

Key Market Drivers

*1. Improved Glycemic Control:* The global non-injectable insulin market benefits significantly from advancements in glycemic control. This category includes insulin delivery methods that eliminate the need for conventional needle injections, encompassing inhalable insulin, oral insulin, and transdermal insulin delivery systems. Consistency in glycemic control is a primary challenge in diabetes management. Injectable insulin, owing to discomfort, pain, and needle anxiety, can deter patient adherence to prescribed insulin regimens. Non-injectable insulin methods offer more convenient and less invasive alternatives, potentially enhancing patient compliance. Improved diabetes management and glycemic control mitigate the risk of complications and hospitalizations. Non-injectable insulin methods, particularly those offering ease of administration, can encourage earlier intervention in diabetes management. Early insulin therapy initiation yields improved glycemic control, slowing disease progression, and leading to better long-term outcomes while reducing diabetes-related healthcare costs. Non-injectable insulin methods expand treatment options for diabetes patients, especially those with needle aversion or physical limitations, potentially enhancing glycemic control. These methods can attract new patient demographics, previously hesitant to initiate insulin therapy due to injection fears, contributing to market growth.

*2. Growing Diabetic Population:* The expanding diabetic population significantly influences the global non-injectable insulin market. Diabetes, characterized by elevated blood sugar levels, exhibits rising prevalence worldwide, driving demand for effective and convenient treatments, including non-injectable insulin. As the diabetic population continues to grow, the demand for diverse diabetes management solutions, including insulin therapies, rises. Non-injectable insulin methods offer alternative solutions for those unwilling or unable to use traditional injectable insulin. This increased demand for convenient and patient-friendly treatments contributes to market expansion. Non-injectable insulin methods cater to a broader spectrum of patients, including those averse to needles or struggling with injections. The growing diabetic population spans diverse age groups and backgrounds, making non-injectable insulin products, such as inhalable or oral insulin, more acceptable across demographics. Adherence to diabetes treatment plans is pivotal for achieving effective glycemic control and averting complications. However, many diabetic patients face difficulties adhering to injectable insulin regimens due to needle fear or inconvenience. Non-injectable insulin methods enhance convenience and ease of use, potentially fostering better adherence and outcomes. With a burgeoning diabetic population, early intervention and preventive measures gain prominence. Non-injectable insulin options can encourage individuals to commence insulin therapy earlier, bolstering glycemic control. Early intervention may delay or prevent diabetes-related complications, curbing healthcare costs and enhancing patients' quality of life. The increasing prevalence of diabetes presents a substantial market opportunity for innovative diabetes management products, motivating research, development, and commercialization efforts, fueling market growth.

*3. Pharmaceutical Industry Investment:* Pharmaceutical industry investments play a pivotal role in influencing the global non-injectable insulin market's growth trajectory. These investments encompass research and development (R&D), clinical trials, manufacturing, marketing, and distribution endeavors related to non-injectable insulin products. Pharmaceutical companies allocate significant resources to R&D, focusing on innovative non-injectable insulin delivery methods. These investments fuel exploration of new technologies, formulations, and administration routes that enhance insulin therapy convenience and patient-friendliness. Progress stemming from these investments propels market expansion by introducing novel and effective treatment options. Pharmaceutical industry investments stimulate innovation within the non-injectable insulin sector, aiming to create products boasting improved efficacy, safety, and patient experience. Innovations may encompass more precise dosing mechanisms, extended-release formulations, and optimized delivery systems. Such advancements garner attention from healthcare professionals and patients, bolstering market adoption and growth. Rigorous clinical trials constitute a pivotal step in introducing new pharmaceutical products to the market. Industry investments in these trials validate non-injectable insulin methods' safety and efficacy, providing the necessary data for regulatory approvals. Positive trial outcomes instill confidence within the medical community, facilitating broader adoption of these products and promoting market growth. Industry investments often extend to educational initiatives, designed to inform healthcare professionals and patients about non-injectable insulin methods. Educational programs assist healthcare providers in making informed treatment decisions and empower patients to select suitable options. Enhanced awareness drives higher adoption rates, positively impacting market growth.

Key Market Challenges

*1. Efficacy and Safety Concerns:* Efficacy and safety concerns can pose hurdles to the global non-injectable insulin market's growth. While non-injectable insulin methods offer convenient alternatives to traditional injections, addressing these concerns is pivotal for gaining the trust of healthcare professionals, regulators, and patients. Efficacy concerns arise when insufficient clinical evidence fails to demonstrate that non-injectable insulin methods provide consistent and reliable blood sugar control comparable to injectable insulin. Healthcare professionals and patients may hesitate to transition to non-injectable options without clear evidence of their effectiveness. If non-injectable insulin products yield inconsistent or unpredictable blood sugar levels, patients and healthcare providers may perceive them as less dependable than injectable insulin, undermining long-term trust in diabetes management. Safety concerns encompass adverse reactions, side effects, and potential interactions with other medications. Ensuring these products' safety is critical for securing regulatory approvals and building trust among patients and healthcare professionals. The long-term effects of non-injectable insulin methods, particularly novel delivery technologies, may remain incompletely understood. Patients and healthcare providers may express concerns about potential complications arising after extended use, impacting their willingness to adopt these methods.

*2. Cost and Affordability:* Cost and affordability are significant factors that can impede the global non-injectable insulin market's growth. While non-injectable insulin methods offer advantages in terms of convenience and patient-friendliness, they may sometimes entail higher costs compared to traditional injectable insulin. Non-injectable insulin methods often involve more complex technology, research, and development, resulting in elevated production costs. Consequently, the initial purchase price of non-injectable insulin products may surpass that of injectable insulin. This cost differential could discourage patients and healthcare providers from selecting non-injectable options. Insurance coverage and reimbursement policies might not fully cover non-injectable insulin method costs, subjecting patients to out-of-pocket expenses that could prove challenging to afford. This lack of coverage constitutes a significant barrier, preventing patients from accessing these alternatives and inhibiting market growth. Diabetes patients frequently contend with ongoing healthcare expenses linked to medications, monitoring equipment, doctor visits, and more. Integrating non-injectable insulin product costs into these expenses can strain patients financially, compelling them to opt for more economical alternatives. Some advanced non-injectable insulin products, especially the more sophisticated ones, may remain inaccessible or unaffordable in low-income regions with limited healthcare resources. This disparity may contribute to health inequities and hinder the global market's expansion. The competitive landscape encompasses established injectable insulin products with a longstanding market presence. New non-injectable alternatives may need to compete on pricing to secure market share, which could be challenging if production costs are higher.

Key Market Trends

*1. Personalized Treatment Approaches:* Personalized treatment approaches empower healthcare providers to select the most suitable non-injectable insulin method based on a patient's medical history, lifestyle, and preferences. This tailored approach heightens the likelihood of treatment adherence and successful outcomes, propelling the adoption of non-injectable methods. When patients participate in their treatment plans and can choose options aligning with their preferences, they are more likely to be satisfied with their care. Non-injectable insulin methods, offering convenience and patient-friendliness, contribute to higher patient satisfaction, fostering market growth. Patients may harbor concerns regarding traditional injections, such as needle anxiety or fear of pain. Personalized treatment approaches can address these concerns by presenting non-injectable insulin alternatives, potentially enhancing patient comfort and acceptance. Distinct age groups harbor varying preferences and requirements. For instance, elderly individuals might grapple with injections due to diminished dexterity, while young children may struggle with traditional insulin injections. Non-injectable insulin methods can be tailored to these age-specific challenges, expanding market reach. Personalized approaches account for patients' lifestyles, encompassing daily routines, work schedules, and dietary habits. Non-injectable insulin options aligning with patient lifestyles are more likely to be adopted, driving market growth. Diabetes management assumes critical importance in preventing complications. Personalized treatment plans can target specific risk factors, ensuring patients receive the most effective treatment to avert complications tied to poor glycemic control. This approach encourages the adoption of non-injectable insulin methods that cater to patient needs.

*2. Regulatory and Reimbursement Advancements:* Regulatory agencies wield substantial influence in ensuring the safety and efficacy of medical products, including non-injectable insulin. Advancements in regulatory pathways designed specifically for innovative delivery methods can expedite the approval process, motivating pharmaceutical companies to invest in non-injectable insulin research and development. A streamlined regulatory pathway accelerates product entry, motivating manufacturers to invest in non-injectable insulin research and development. Robust regulatory guidelines provide manufacturers with a clear roadmap for product development and clinical trials, ensuring compliance with specific standards while introducing innovative products to the market. Regulatory agencies adopting risk-based oversight tailor evaluation processes to the distinctive attributes of non-injectable insulin methods, balancing stringent safety standards with the unique benefits and challenges posed by these delivery systems. Regulatory advancements permitting expanded indications for non-injectable insulin methods broaden their potential patient base. Gaining approval for diverse diabetes types or specific patient groups amplifies market outreach. Reimbursement advancements offering improved coverage for non-injectable insulin methods incentivize healthcare providers to prescribe these options. Enhanced reimbursement policies reduce financial barriers for patients, making non-injectable insulin more accessible and spurring adoption. Collaboration between pharmaceutical companies and payers (insurance providers and government healthcare programs) can yield mutually advantageous agreements. Negotiating pricing and reimbursement terms for non-injectable insulin products ensures affordability for patients, facilitating adoption and market expansion. International alignment of regulatory and reimbursement policies eases simultaneous market entry across multiple regions, reducing barriers and accelerating global non-injectable insulin product expansion.

Segmental Insights

Type Insights: Within the product category, the pills segment is poised to experience substantial market growth throughout the forecast period. Several factors contribute to this growth, including:

- Needle aversion or fear among many individuals with diabetes: Oral insulin pills offer a more comfortable and familiar medication delivery method, reducing psychological barriers to insulin therapy.

- Enhanced treatment adherence: The convenience of taking an insulin pill compared to an injection promotes adherence to treatment plans, contributing to better glycemic control and patient outcomes.

- Early intervention: Oral insulin pills can encourage early intervention in diabetes management, attracting individuals hesitant to initiate injectable insulin therapy.

- Expanded patient base: Pills cater to a wide patient demographic, including those who were previously resistant to insulin therapy due to injection-related concerns, furthering market growth.

- Patient empowerment: Pills enable patients to independently manage their diabetes, offering ease of administration without requiring medical personnel or specialized equipment.

End Use Insights: In terms of end-use segments, drug stores have exerted a dominant influence in the market. Drug stores, often conveniently located in urban and suburban areas, ensure easy access to non-injectable insulin products for a broad patient population. This accessibility guarantees that these products are readily available, enhancing patient convenience. Pharmacists at drug stores, well-trained healthcare professionals, play a crucial role in providing patients with information about non-injectable insulin options. They can explain product functionalities, benefits, and administration techniques, augmenting patient awareness and understanding. Drug stores serve as essential points for patients to procure prescribed medications, including non-injectable insulin products. Pharmacists guide patients on proper usage, storage, and potential side effects, promoting adherence and favorable treatment outcomes. Some non-injectable insulin products may be available over-the-counter (OTC), enabling patients to purchase them without a prescription. Drug stores can stock these OTC options, granting patients greater autonomy in diabetes management. Health screenings, including blood glucose testing, offered by some drug stores provide pharmacists with opportunities to educate patients about non-injectable insulin methods and encourage them to consider these alternatives. Drug stores can actively promote non-injectable insulin options through in-store displays, brochures, and informational sessions, heightening patient awareness and fostering exploration of these alternatives.

Regional Insights: North America, specifically the Non-Injectable Insulin Market, asserted its dominance in 2022. The United States and Canada, part of North America, feature advanced healthcare systems, research institutions, and pharmaceutical industries, all supporting the development, clinical testing, and commercialization of innovative medical products like non-injectable insulin. This robust infrastructure facilitates technological innovation, including advancements in drug delivery systems. Non-injectable insulin methods demand sophisticated technology, benefiting from North America's innovation ecosystem. The pharmaceutical industry in North America thrives, with numerous companies investing in research and development. These firms possess the resources necessary for developing and marketing non-injectable insulin products, igniting market growth. North America often serves as a preferred location for conducting clinical trials, benefiting from its diverse population, well-established regulatory framework, and skilled medical professionals. Clinical trials constitute a pivotal stage for demonstrating the safety and efficacy of new medical products, playing a pivotal role in their introduction to the market. Public awareness campaigns and healthcare initiatives enhance patient knowledge of various treatment options. As patients become more acquainted with non-injectable insulin methods, they are likely to express interest, spurring demand. Patient preferences align with the convenience and user-friendliness offered by non-injectable methods, further fueling adoption and market expansion in North America.

Key Market Players
  • Midatech Pharma Plc
  • Shreya Life Sciences Pvt. Ltd.
  • Boston Therapeutics, Inc.
  • Coromed, Inc.
  • Diabetology Ltd.
  • Emisphere Technologies, Inc.
  • Oramed Pharmaceuticals, Inc.
  • Diasome Pharmaceuticals, Inc.
  • Generex Biotechnology Corp.
  • Biodel, Inc.
Report Scope:

In this report, the Global Non-Injectable Insulin Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:
  • Non-Injectable Insulin Market, By Product:
  • Pills
  • Sprays
  • Others
  • Non-Injectable Insulin Market, By Distribution Channel:
  • Hospital Pharmacies
  • Online Pharmacies
  • Drug Stores
  • Non-Injectable Insulin Market, By Region:
  • North America
    • United States
    • Canada
    • Mexico
  • Europe
    • France
    • United Kingdom
    • Italy
    • Germany
    • Spain
  • Asia-Pacific
    • China
    • India
    • Japan
    • Australia
    • South Korea
  • South America
    • Brazil
    • Argentina
    • Colombia
  • Middle East & Africa
    • South Africa
    • Saudi Arabia
    • UAE
    • Kuwait
    • Turkey
    • Egypt
Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the Global Non-Injectable Insulin Market.

Available Customizations:

Global Non-Injectable Insulin market report with the given market data, Tech Sci Research offers customizations according to a company's specific needs. The following customization options are available for the report:

Company Information
  • Detailed analysis and profiling of additional market players (up to five).
1. PRODUCT OVERVIEW

1.1. Market Definition
1.2. Scope of the Market
  1.2.1. Markets Covered
  1.2.2. Years Considered for Study
  1.2.3. Key Market Segmentations

2. RESEARCH METHODOLOGY

2.1. Objective of the Study
2.2. Baseline Methodology
2.3. Key Industry Partners
2.4. Major Association and Secondary Sources
2.5. Forecasting Methodology
2.6. Data Triangulation & Validation
2.7. Assumptions and Limitations

3. EXECUTIVE SUMMARY

3.1. Overview of the Market
3.2. Overview of Key Market Segmentations
3.3. Overview of Key Market Players
3.4. Overview of Key Regions/Countries
3.5. Overview of Market Drivers, Challenges, Trends

4. VOICE OF CUSTOMER


5. GLOBAL NON-INJECTABLE INSULIN MARKET OUTLOOK

5.1. Market Size & Forecast
  5.1.1. By Value
5.2. Market Share & Forecast
  5.2.1. By Product (Pills, Sprays, and Others)
  5.2.2. By Distribution Channel (Hospital Pharmacies, and Online Pharmacies, Drug Stores)
  5.2.3. By Region (North America, Europe, Asia Pacific, South America, Middle East & Africa)
  5.2.4. By Company (2022)
5.3. Market Map
  5.3.1 By Product
  5.3.2 By Distribution Channel
  35.3.4 By Region

6. NORTH AMERICA NON-INJECTABLE INSULIN MARKET OUTLOOK

6.1. Market Size & Forecast
  6.1.1. By Value
6.2. Market Share & Forecast
  6.2.1. By Product (Pills, Sprays, and Others)
  6.2.2. By Distribution Channel (Hospital Pharmacies, and Online Pharmacies, Drug Stores)
  6.2.3. By Country
6.3. North America: Country Analysis
  6.3.1. United States Non-Injectable Insulin Market Outlook
    6.3.1.1. Market Size & Forecast
      6.3.1.1.1. By Value
    6.3.1.2. Market Share & Forecast
      6.3.1.2.1. By Product
      6.3.1.2.2. By Distribution Channel
  6.3.2. Canada Non-Injectable Insulin Market Outlook
    6.3.2.1. Market Size & Forecast
      6.3.2.1.1. By Value
    6.3.2.2. Market Share & Forecast
      6.3.2.2.1. By Product
      6.3.2.2.2. By Distribution Channel
  6.3.3. Mexico Non-Injectable Insulin Market Outlook
    6.3.3.1. Market Size & Forecast
      6.3.3.1.1. By Value
    6.3.3.2. Market Share & Forecast
      6.3.3.2.1. By Product
      6.3.3.2.2. By Distribution Channel

7. EUROPE NON-INJECTABLE INSULIN MARKET OUTLOOK

7.1. Market Size & Forecast
  7.1.1. By Value
7.2. Market Share & Forecast
  7.2.1. By Product (Pills, Sprays, and Others)
  7.2.2. By Distribution Channel (Hospital Pharmacies, and Online Pharmacies, Drug Stores)
  7.2.3. By Country
7.3. Europe: Country Analysis
  7.3.1. France Non-Injectable Insulin Market Outlook
    7.3.1.1. Market Size & Forecast
      7.3.1.1.1. By Value
    7.3.1.2. Market Share & Forecast
      7.3.1.2.1. By Product
      7.3.1.2.2. By Distribution Channel
  7.3.2. Germany Non-Injectable Insulin Market Outlook
    7.3.2.1. Market Size & Forecast
      7.3.2.1.1. By Value
    7.3.2.2. Market Share & Forecast
      7.3.2.2.1. By Product
      7.3.2.2.2. By Distribution Channel
  7.3.3. United Kingdom Non-Injectable Insulin Market Outlook
    7.3.3.1. Market Size & Forecast
      7.3.3.1.1. By Value
    7.3.3.2. Market Share & Forecast
      7.3.3.2.1. By Product
      7.3.3.2.2. By Distribution Channel
  7.3.4. Italy Non-Injectable Insulin Market Outlook
    7.3.4.1. Market Size & Forecast
      7.3.4.1.1. By Value
    7.3.4.2. Market Share & Forecast
      7.3.4.2.1. By Product
      7.3.4.2.2. By Distribution Channel
  7.3.5. Spain Non-Injectable Insulin Market Outlook
    7.3.5.1. Market Size & Forecast
      7.3.5.1.1. By Value
    7.3.5.2. Market Share & Forecast
      7.3.5.2.1. By Product
      7.3.5.2.2. By Distribution Channel

8. ASIA-PACIFIC NON-INJECTABLE INSULIN MARKET OUTLOOK

8.1. Market Size & Forecast
  8.1.1. By Value
8.2. Market Share & Forecast
  8.2.1. By Product (Pills, Sprays, and Others)
  8.2.2. By Distribution Channel (Hospital Pharmacies, and Online Pharmacies, Drug Stores)
  8.2.3. By Country
8.3. Asia-Pacific: Country Analysis
  8.3.1. China Non-Injectable Insulin Market Outlook
    8.3.1.1. Market Size & Forecast
      8.3.1.1.1. By Value
    8.3.1.2. Market Share & Forecast
      8.3.1.2.1. By Product
      8.3.1.2.2. By Distribution Channel
  8.3.2. India Non-Injectable Insulin Market Outlook
    8.3.2.1. Market Size & Forecast
      8.3.2.1.1. By Value
    8.3.2.2. Market Share & Forecast
      8.3.2.2.1. By Product
      8.3.2.2.2. By Distribution Channel
  8.3.3. Japan Non-Injectable Insulin Market Outlook
    8.3.3.1. Market Size & Forecast
      8.3.3.1.1. By Value
    8.3.3.2. Market Share & Forecast
      8.3.3.2.1. By Product
      8.3.3.2.2. By Distribution Channel
  8.3.4. South Korea Non-Injectable Insulin Market Outlook
    8.3.4.1. Market Size & Forecast
      8.3.4.1.1. By Value
    8.3.4.2. Market Share & Forecast
      8.3.4.2.1. By Product
      8.3.4.2.2. By Distribution Channel
  8.3.5. Australia Non-Injectable Insulin Market Outlook
    8.3.5.1. Market Size & Forecast
      8.3.5.1.1. By Value
    8.3.5.2. Market Share & Forecast
      8.3.5.2.1. By Product
      8.3.5.2.2. By Distribution Channel

9. SOUTH AMERICA NON-INJECTABLE INSULIN MARKET OUTLOOK

9.1. Market Size & Forecast
  9.1.1. By Value
9.2. Market Share & Forecast
  9.2.1. By Product (Pills, Sprays, and Others)
  9.2.2. By Distribution Channel (Hospital Pharmacies, and Online Pharmacies, Drug Stores)
  9.2.3. By Country
9.3. South America: Country Analysis
  9.3.1. Brazil Non-Injectable Insulin Market Outlook
    9.3.1.1. Market Size & Forecast
      9.3.1.1.1. By Value
    9.3.1.2. Market Share & Forecast
      9.3.1.2.1. By Product
      9.3.1.2.2. By Distribution Channel
  9.3.2. Argentina Non-Injectable Insulin Market Outlook
    9.3.2.1. Market Size & Forecast
      9.3.2.1.1. By Value
    9.3.2.2. Market Share & Forecast
      9.3.2.2.1. By Product
      9.3.2.2.2. By Distribution Channel
  9.3.3. Colombia Non-Injectable Insulin Market Outlook
    9.3.3.1. Market Size & Forecast
      9.3.3.1.1. By Value
    9.3.3.2. Market Share & Forecast
      9.3.3.2.1. By Product
      9.3.3.2.2. By Distribution Channel

10. MIDDLE EAST AND AFRICA NON-INJECTABLE INSULIN MARKET OUTLOOK

10.1. Market Size & Forecast
  10.1.1. By Value
10.2. Market Share & Forecast
  10.2.1. By Product (Pills, Sprays, and Others)
  10.2.2. By Distribution Channel (Hospital Pharmacies, and Online Pharmacies, Drug Stores)
  10.2.3. By Country
10.3. MEA: Country Analysis
  10.3.1. South Africa Non-Injectable Insulin Market Outlook
    10.3.1.1. Market Size & Forecast
      10.3.1.1.1. By Value
    10.3.1.2. Market Share & Forecast
      10.3.1.2.1. By Product
      10.3.1.2.2. By Distribution Channel
  10.3.2. Saudi Arabia Non-Injectable Insulin Market Outlook
    10.3.2.1. Market Size & Forecast
      10.3.2.1.1. By Value
    10.3.2.2. Market Share & Forecast
      10.3.2.2.1. By Product
      10.3.2.2.2. By Distribution Channel
  10.3.3. UAE Non-Injectable Insulin Market Outlook
    10.3.3.1. Market Size & Forecast
      10.3.3.1.1. By Value
    10.3.3.2. Market Share & Forecast
      10.3.3.2.1. By Product
      10.3.3.2.2. By Distribution Channel

11. MARKET DYNAMICS

11.1. Drivers
11.2. Challenges

12. MARKET TRENDS & DEVELOPMENTS

12.1. Recent Development
12.2. Mergers & Acquisitions
12.3. Product Launches

13. GLOBAL NON-INJECTABLE INSULIN MARKET: SWOT ANALYSIS


14. PORTER’S FIVE FORCES ANALYSIS

14.1. Competition in the Industry
14.2. Potential of New Entrants
14.3. Power of Suppliers
14.4. Power of Customers
14.5. Threat of Substitute Products

15. COMPETITIVE LANDSCAPE

15.1. Business Overview
15.2. Product Offerings
15.3. Recent Developments
15.4. Financials (As Reported)
15.5. Key Personnel
15.6. SWOT Analysis
  15.6.1 Midatech Pharma Plc
  15.6.2 Shreya Life Sciences Pvt. Ltd.
  15.6.3 Boston Therapeutics, Inc.
  15.6.4 Coromed, Inc.
  15.6.5 Diabetology Ltd.
  15.6.6 Emisphere Technologies, Inc.
  15.6.7 Oramed Pharmaceuticals, Inc.
  15.6.8 Diasome Pharmaceuticals, Inc.
  15.6.9 Generex Biotechnology Corp.
  15.6.10 Biodel, Inc.

16. STRATEGIC RECOMMENDATIONS


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