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Myasthenia Gravis Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

May 2024 | 134 pages | ID: M514FE5C5DDAEN
IMARC Group

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The 7 major myasthenia gravis markets reached a value of US$ 1.3 Billion in 2023. Looking forward, IMARC Group expects the 7MM to reach US$ 2.1 Billion by 2034, exhibiting a growth rate (CAGR) of 4.99% during 2024-2034.

The myasthenia gravis market has been comprehensively analyzed in IMARC's new report titled "Myasthenia Gravis Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Myasthenia gravis (MG) is a chronic autoimmune condition which weakens and exhausts muscles, particularly those that control facial expression, eye movement, and swallowing. The loss of acetylcholine receptors at the neuromuscular junction reduces the regular transmission of nerve impulses to the muscles, hence leading to weakness. The signs and symptoms of MG can vary from person to person and can appear suddenly or gradually. Some of the common symptoms of MG include fatigue, muscle weakness, droopy eyelids, shortness of breath, difficulty in speaking, rapid eye movements, muscle twitching, etc. The diagnosis of MG generally involves a combination of clinical evaluations, tests, and procedures, such as blood tests, electromyography (EMG), MRI, and CT scan. Additionally, myasthenia gravis can also be identified using a diagnostic test known as the Edrophonium (Tensilon) test, which involves temporarily administering a drug to increase muscle strength. Some additional tests might also be required to assess the type and severity of MG and track the disease's development.

The rising prevalence of autoimmune illnesses and viral infections, such as the Epstein-Barr virus and cytomegalovirus, coupled with the growing unmet need for treatments, is primarily driving the global myasthenia gravis market. In addition to this, the escalating utilization of cholinesterase inhibitors, which assist in improving muscle strength by increasing the availability of acetylcholine at the neuromuscular junction, to treat the ailment is creating a positive outlook for the market. Furthermore, the widespread adoption of immunosuppressive therapy to suppress the immune system and reduce the production of antibodies that attack the acetylcholine receptors, is also bolstering the market growth. Besides this, the emerging popularity of plasmapheresis therapy, which involves removing the plasma from the blood and replacing it with intravenous fluids to remove harmful antibodies for treating MG is acting as a significant growth-inducing factor. Moreover, the introduction of several initiatives by numerous government bodies across the globe to create awareness regarding myasthenia gravis and support faster approvals of pipeline drugs and clinical trials that encourage the entry of new products is further augmenting the global market. Additionally, various key players are making extensive investments in developing monoclonal antibodies that block the activity of complement proteins involved in the immune response. This, in turn, is expected to drive the global myasthenia gravis in the coming years.

IMARC Group's new report provides an exhaustive analysis of the myasthenia gravis market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report, the United States has the largest patient pool for Myasthenia gravis and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the myasthenia gravis market in any manner.

Time Period of the Study

Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034

Countries Covered

United States
Germany
France
United Kingdom
Italy
Spain
Japan

Analysis Covered Across Each Country

Historical, current, and future epidemiology scenario
Historical, current, and future performance of the myasthenia gravis market
Historical, current, and future performance of various therapeutic categories in the market
Sales of various drugs across the myasthenia gravis market
Reimbursement scenario in the market
In-market and pipeline drugs
Competitive Landscape:
This report also provides a detailed analysis of the current myasthenia gravis marketed drugs and late-stage pipeline drugs.

In-Market Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.

Key Questions Answered in this Report:
Market Insights

How has the myasthenia gravis market performed so far and how will it perform in the coming years?
What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
What was the country-wise size of the myasthenia gravis market across the seven major markets in 2023 and what will it look like in 2034?
What is the growth rate of the myasthenia gravis market across the seven major markets and what will be the expected growth over the next ten years?
What are the key unmet needs in the market?

Epidemiology Insights

What is the number of prevalent cases (?2018-2034?) of myasthenia gravis across the seven major markets?
What is the number of prevalent cases (?2018-2034?) of myasthenia gravis by age across the seven major markets?
What is the number of prevalent cases (?2018-2034?) of myasthenia gravis by gender across the seven major markets?
What is the number of prevalent cases (?2018-2034?) of myasthenia gravis by type across the seven major markets?
How many patients are diagnosed (?2018-2034?) with myasthenia gravis across the seven major markets?
What is the size of the myasthenia gravis patient pool (2018-2023) across the seven major markets?
What would be the forecasted patient pool (2024-2034) across the seven major markets?
What are the key factors driving the epidemiological trend of myasthenia gravis ?
What will be the growth rate of patients across the seven major markets?

Myasthenia Gravis: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

What are the current marketed drugs and what are their market performance?
What are the key pipeline drugs and how are they expected to perform in the coming years?
How safe are the current marketed drugs and what are their efficacies?
How safe are the late-stage pipeline drugs and what are their efficacies?
What are the current treatment guidelines for myasthenia gravis drugs across the seven major markets?
Who are the key companies in the market and what are their market shares?
What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the myasthenia gravis market?
What are the key regulatory events related to the myasthenia gravis market?
What is the structure of clinical trial landscape by status related to the myasthenia gravis market?
What is the structure of clinical trial landscape by phase related to the myasthenia gravis market?
What is the structure of clinical trial landscape by route of administration related to the myasthenia gravis market?
1 PREFACE

2 SCOPE AND METHODOLOGY

2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
  2.3.1 Primary Sources
  2.3.2 Secondary Sources
2.4 Market Estimation
  2.4.1 Bottom-Up Approach
  2.4.2 Top-Down Approach
2.5 Forecasting Methodology

3 EXECUTIVE SUMMARY

4 MYASTHENIA GRAVIS - INTRODUCTION

4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence

5 MYASTHENIA GRAVIS - DISEASE OVERVIEW

5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment

6 PATIENT JOURNEY

7 MYASTHENIA GRAVIS - EPIDEMIOLOGY AND PATIENT POPULATION

7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
  7.2.1 Epidemiology Scenario (2018-2023)
  7.2.2 Epidemiology Forecast (2024-2034)
  7.2.3 Epidemiology by Age (?2018-2034?)
  7.2.4 Epidemiology by Gender (?2018-2034?)
  7.2.5 Epidemiology by Type (?2018-2034?)
  7.2.6 Diagnosed Cases (?2018-2034?)
  7.2.7 Patient Pool/Treated Cases (?2018-2034?)
7.3 Epidemiology Scenario - United States
  7.3.1 Epidemiology Scenario (2018-2023)
  7.3.2 Epidemiology Forecast (2024-2034)
  7.3.3 Epidemiology by Age (?2018-2034?)
  7.3.4 Epidemiology by Gender (?2018-2034?)
  7.3.5 Epidemiology by Type (?2018-2034?)
  7.3.6 Diagnosed Cases (?2018-2034?)
  7.3.7 Patient Pool/Treated Cases (?2018-2034?)
7.4 Epidemiology Scenario - Germany
  7.4.1 Epidemiology Scenario (2018-2023)
  7.4.2 Epidemiology Forecast (2024-2034)
  7.4.3 Epidemiology by Age (?2018-2034?)
  7.4.4 Epidemiology by Gender (?2018-2034?)
  7.4.5 Epidemiology by Type (?2018-2034?)
  7.4.6 Diagnosed Cases (?2018-2034?)
  7.4.7 Patient Pool/Treated Cases (?2018-2034?)
7.5 Epidemiology Scenario - France
  7.5.1 Epidemiology Scenario (2018-2023)
  7.5.2 Epidemiology Forecast (2024-2034)
  7.5.3 Epidemiology by Age (?2018-2034?)
  7.5.4 Epidemiology by Gender (?2018-2034?)
  7.5.5 Epidemiology by Type (?2018-2034?)
  7.5.6 Diagnosed Cases (?2018-2034?)
  7.5.7 Patient Pool/Treated Cases (?2018-2034?)
7.6 Epidemiology Scenario - United Kingdom
  7.6.1 Epidemiology Scenario (2018-2023)
  7.6.2 Epidemiology Forecast (2024-2034)
  7.6.3 Epidemiology by Age (?2018-2034?)
  7.6.4 Epidemiology by Gender (?2018-2034?)
  7.6.5 Epidemiology by Type (?2018-2034?)
  7.6.6 Diagnosed Cases (?2018-2034?)
  7.6.7 Patient Pool/Treated Cases (?2018-2034?)
7.7 Epidemiology Scenario - Italy
  7.7.1 Epidemiology Scenario (2018-2023)
  7.7.2 Epidemiology Forecast (2024-2034)
  7.7.3 Epidemiology by Age (?2018-2034?)
  7.7.4 Epidemiology by Gender (?2018-2034?)
  7.7.5 Epidemiology by Type (?2018-2034?)
  7.7.6 Diagnosed Cases (?2018-2034?)
  7.7.7 Patient Pool/Treated Cases (?2018-2034?)
7.8 Epidemiology Scenario - Spain
  7.8.1 Epidemiology Scenario (2018-2023)
  7.8.2 Epidemiology Forecast (2024-2034)
  7.8.3 Epidemiology by Age (?2018-2034?)
  7.8.4 Epidemiology by Gender (?2018-2034?)
  7.8.5 Epidemiology by Type (?2018-2034?)
  7.8.6 Diagnosed Cases (?2018-2034?)
  7.8.7 Patient Pool/Treated Cases (?2018-2034?)
7.9 Epidemiology Scenario - Japan
  7.9.1 Epidemiology Scenario (2018-2023)
  7.9.2 Epidemiology Forecast (2024-2034)
  7.9.3 Epidemiology by Age (?2018-2034?)
  7.9.4 Epidemiology by Gender (?2018-2034?)
  7.9.5 Epidemiology by Type (?2018-2034?)
  7.9.6 Diagnosed Cases (?2018-2034?)
  7.9.7 Patient Pool/Treated Cases (?2018-2034?)

8 MYASTHENIA GRAVIS - TREATMENT ALGORITHM, GUIDELINES, AND MEDICAL PRACTICES

8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm

9 MYASTHENIA GRAVIS - UNMET NEEDS

10 MYASTHENIA GRAVIS - KEY ENDPOINTS OF TREATMENT

11 MYASTHENIA GRAVIS - MARKETED PRODUCTS

11.1 List of Myasthenia Gravis Marketed Drugs Across the Top 7 Markets
  11.1.1 Efgartigimod alfa - Argenx
    11.1.1.1 Drug Overview
    11.1.1.2 Mechanism of Action
    11.1.1.3 Regulatory Status
    11.1.1.4 Clinical Trial Results
    11.1.1.5 Sales Across Major Markets
  11.1.2 Ravulizumab – Alexion Pharmaceuticals
    11.1.2.1 Drug Overview
    11.1.2.2 Mechanism of Action
    11.1.2.3 Regulatory Status
    11.1.2.4 Clinical Trial Results
    11.1.2.5 Sales Across Major Markets
  11.1.3 Eculizumab - Alexion Pharmaceuticals
    11.1.3.1 Drug Overview
    11.1.3.2 Mechanism of Action
    11.1.3.3 Regulatory Status
    11.1.3.4 Clinical Trial Results
    11.1.3.5 Sales Across Major Markets
  11.1.4 Mestinon – Milla Pharmaceuticals
    11.1.4.1 Drug Overview
    11.1.4.2 Mechanism of Action
    11.1.4.3 Regulatory Status
    11.1.4.4 Clinical Trial Results
    11.1.4.5 Sales Across Major Markets
Kindly note that the above only represents a partial list of marketed drugs, and the complete list has been provided in the report.

12 MYASTHENIA GRAVIS - PIPELINE DRUGS

12.1 List of Myasthenia Gravis Pipeline Drugs Across the Top 7 Markets
  12.1.1 Satralizumab - Chugai Pharmaceuticals/Roche
    12.1.1.1 Drug Overview
    12.1.1.2 Mechanism of Action
    12.1.1.3 Clinical Trial Results
    12.1.1.4 Safety and Efficacy
    12.1.1.5 Regulatory Status
  12.1.2 Nipocalimab - Momenta Pharamaceuticals
    12.1.2.1 Drug Overview
    12.1.2.2 Mechanism of Action
    12.1.2.3 Clinical Trial Results
    12.1.2.4 Safety and Efficacy
    12.1.2.5 Regulatory Status
  12.1.3 Inebilizumab - Viela Bio
    12.1.3.1 Drug Overview
    12.1.3.2 Mechanism of Action
    12.1.3.3 Clinical Trial Results
    12.1.3.4 Safety and Efficacy
    12.1.3.5 Regulatory Status
  12.1.4 Rozanolixizumab - UCB
    12.1.4.1 Drug Overview
    12.1.4.2 Mechanism of Action
    12.1.4.3 Clinical Trial Results
    12.1.4.4 Safety and Efficacy
    12.1.4.5 Regulatory Status
  12.1.5 Gefurulimab - Alexion Pharmaceuticals
    12.1.5.1 Drug Overview
    12.1.5.2 Mechanism of Action
    12.1.5.3 Clinical Trial Results
    12.1.5.4 Safety and Efficacy
    12.1.5.5 Regulatory Status
Kindly note that the above only represents a partial list of pipeline drugs, and the complete list has been provided in the report.

13. MYASTHENIA GRAVIS - ATTRIBUTE ANALYSIS OF KEY MARKETED AND PIPELINE DRUGS

14. MYASTHENIA GRAVIS – CLINICAL TRIAL LANDSCAPE

14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events

15 MYASTHENIA GRAVIS - MARKET SCENARIO

15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
  15.2.1 Myasthenia Gravis - Market Size
    15.2.1.1 Market Size (2018-2023)
    15.2.1.2 Market Forecast (2024-2034)
  15.2.2 Myasthenia Gravis - Market Size by Therapies
    15.2.2.1 Market Size by Therapies (2018-2023)
    15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
  15.3.1 Myasthenia Gravis - Market Size
    15.3.1.1 Market Size (2018-2023)
    15.3.1.2 Market Forecast (2024-2034)
  15.3.2 Myasthenia Gravis - Market Size by Therapies
    15.3.2.1 Market Size by Therapies (2018-2023)
    15.3.2.2 Market Forecast by Therapies (2024-2034)
  15.3.3 Myasthenia Gravis - Access and Reimbursement Overview
15.4 Market Scenario - Germany
  15.4.1 Myasthenia Gravis - Market Size
    15.4.1.1 Market Size (2018-2023)
    15.4.1.2 Market Forecast (2024-2034)
  15.4.2 Myasthenia Gravis - Market Size by Therapies
    15.4.2.1 Market Size by Therapies (2018-2023)
    15.4.2.2 Market Forecast by Therapies (2024-2034)
  15.4.3 Myasthenia Gravis - Access and Reimbursement Overview
15.5 Market Scenario - France
  15.5.1 Myasthenia Gravis - Market Size
    15.5.1.1 Market Size (2018-2023)
    15.5.1.2 Market Forecast (2024-2034)
  15.5.2 Myasthenia Gravis - Market Size by Therapies
    15.5.2.1 Market Size by Therapies (2018-2023)
    15.5.2.2 Market Forecast by Therapies (2024-2034)
  15.5.3 Myasthenia Gravis - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
  15.6.1 Myasthenia Gravis - Market Size
    15.6.1.1 Market Size (2018-2023)
    15.6.1.2 Market Forecast (2024-2034)
  15.6.2 Myasthenia Gravis - Market Size by Therapies
    15.6.2.1 Market Size by Therapies (2018-2023)
    15.6.2.2 Market Forecast by Therapies (2024-2034)
  15.6.3 Myasthenia Gravis - Access and Reimbursement Overview
15.7 Market Scenario - Italy
  15.7.1 Myasthenia Gravis - Market Size
    15.7.1.1 Market Size (2018-2023)
    15.7.1.2 Market Forecast (2024-2034)
  15.7.2 Myasthenia Gravis - Market Size by Therapies
    15.7.2.1 Market Size by Therapies (2018-2023)
    15.7.2.2 Market Forecast by Therapies (2024-2034)
  15.7.3 Myasthenia Gravis - Access and Reimbursement Overview
15.8 Market Scenario - Spain
  15.8.1 Myasthenia Gravis - Market Size
    15.8.1.1 Market Size (2018-2023)
    15.8.1.2 Market Forecast (2024-2034)
  15.8.2 Myasthenia Gravis - Market Size by Therapies
    15.8.2.1 Market Size by Therapies (2018-2023)
    15.8.2.2 Market Forecast by Therapies (2024-2034)
  15.8.3 Myasthenia Gravis - Access and Reimbursement Overview
15.9 Market Scenario - Japan
  15.9.1 Myasthenia Gravis - Market Size
    15.9.1.1 Market Size (2018-2023)
    15.9.1.2 Market Forecast (2024-2034)
  15.9.2 Myasthenia Gravis - Market Size by Therapies
    15.9.2.1 Market Size by Therapies (2018-2023)
    15.9.2.2 Market Forecast by Therapies (2024-2034)
  15.9.3 Myasthenia Gravis - Access and Reimbursement Overview

16 MYASTHENIA GRAVIS - RECENT EVENTS AND INPUTS FROM KEY OPINION LEADERS

17 MYASTHENIA GRAVIS MARKET - SWOT ANALYSIS

17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats

18 MYASTHENIA GRAVIS MARKET – STRATEGIC RECOMMENDATIONS

19 APPENDIX


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