Metastatic HER2-Positive Breast Cancer Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034
The 7 major metastatic HER2-positive breast cancer markets are expected to exhibit a CAGR of 1.18% during 2024-2034.
The metastatic HER2-positive breast cancer market has been comprehensively analyzed in IMARC's new report titled "Metastatic HER2-Positive Breast Cancer Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Metastatic HER2 (human epidermal growth factor receptor 2)-positive breast cancer is an advanced stage of breast cancer characterized by the presence of HER2 protein overexpression. It tends to be more aggressive than other forms of cancer due to its accelerated growth and increased likelihood of spreading beyond the breast tissue. The symptoms of this illness may include a palpable lump in the breast or underarm, alterations in breast shape or size, skin dimpling, nipple changes, persistent pain, and bone fractures. As the cancer advances, it can spread to distant organs, such as the brain, bones, lungs, or liver, causing further complications. The diagnosis of metastatic HER2-positive breast cancer typically requires a combination of clinical findings and physical investigations. The healthcare provider will also perform numerous diagnostic procedures, including a mammogram or ultrasound, a biopsy of the tumor tissue to confirm HER2 positivity, and imaging studies to determine the extent of metastasis.
The increasing incidences of genetic variations in the BRCA1 and BRCA2 genes, resulting in uncontrolled growth and division of abnormal cells that originate in the breast tissue, are primarily driving the metastatic HER2-positive breast cancer market. In addition to this, the inflating utilization of innovative approaches, such as antibody-drug conjugates and immune checkpoint inhibitors, which help in harnessing the body's immune response to combat cancerous cells, is also creating a positive outlook for the market. Moreover, the widespread adoption of supportive therapies, including immunotherapies, bisphosphonates, and pain management strategies, aimed at enhancing patients' overall well-being and mitigating treatment-related complications, is further bolstering the market growth. Apart from this, the rising usage of precision medicine approaches, since they involve tailoring treatments based on the genetic makeup of the tumor, is acting as another significant growth-inducing factor. Additionally, the emerging popularity of minimally invasive procedures, such as radiofrequency ablation and cryoablation to precisely target and eliminate tumor masses in individuals suffering from the illness is also augmenting the market growth. Furthermore, the escalating application of gene-targeting treatments that aim to correct or inhibit the overexpression of the HER2 gene is expected to drive the metastatic HER2-positive breast cancer market during the forecast period.
IMARC Group's new report provides an exhaustive analysis of the metastatic HER2-positive breast cancer market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for metastatic HER2-positive breast cancer and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the metastatic HER2-positive breast cancer market in any manner.
Time Period of the Study
Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034
Countries Covered
United States
Germany
France
United Kingdom
Italy
Spain
Japan
Analysis Covered Across Each Country
Historical, current, and future epidemiology scenario
Historical, current, and future performance of the metastatic HER2-positive breast cancer market
Historical, current, and future performance of various therapeutic categories in the market
Sales of various drugs across the metastatic HER2-positive breast cancer market
Reimbursement scenario in the market
In-market and pipeline drugs
Competitive Landscape:
This report also provides a detailed analysis of the current metastatic HER2-positive breast cancer marketed drugs and late-stage pipeline drugs.
In-Market Drugs
Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance
Late-Stage Pipeline Drugs
Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance
*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.
Key Questions Answered in this Report:
Market Insights
How has the metastatic HER2-positive breast cancer market performed so far and how will it perform in the coming years?
What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
What was the country-wise size of the metastatic HER2-positive breast cancer market across the seven major markets in 2023 and what will it look like in 2034?
What is the growth rate of the metastatic HER2-positive breast cancer market across the seven major markets and what will be the expected growth over the next ten years?
What are the key unmet needs in the market?
Epidemiology Insights
What is the number of prevalent cases (?2018-2034?) of metastatic HER2-positive breast cancer across the seven major markets?
What is the number of prevalent cases (?2018-2034?) of metastatic HER2-positive breast cancer by age across the seven major markets?
What is the number of prevalent cases (?2018-2034?) of metastatic HER2-positive breast cancer by gender across the seven major markets?
How many patients are diagnosed (?2018-2034?) with metastatic HER2-positive breast cancer across the seven major markets?
What is the size of the metastatic HER2-positive breast cancer patient pool (2018-2023) across the seven major markets?
What would be the forecasted patient pool (2024-2034) across the seven major markets?
What are the key factors driving the epidemiological trend of metastatic HER2-positive breast cancer?
What will be the growth rate of patients across the seven major markets?
Metastatic HER2-Positive Breast Cancer: Current Treatment Scenario, Marketed Drugs and Emerging Therapies
What are the current marketed drugs and what are their market performance?
What are the key pipeline drugs and how are they expected to perform in the coming years?
How safe are the current marketed drugs and what are their efficacies?
How safe are the late-stage pipeline drugs and what are their efficacies?
What are the current treatment guidelines for metastatic HER2-positive breast cancer drugs across the seven major markets?
Who are the key companies in the market and what are their market shares?
What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the metastatic HER2-positive breast cancer market?
What are the key regulatory events related to the metastatic HER2-positive breast cancer market?
What is the structure of clinical trial landscape by status related to the metastatic HER2-positive breast cancer market?
What is the structure of clinical trial landscape by phase related to the metastatic HER2-positive breast cancer market?
What is the structure of clinical trial landscape by route of administration related to the metastatic HER2-positive breast cancer market?
The metastatic HER2-positive breast cancer market has been comprehensively analyzed in IMARC's new report titled "Metastatic HER2-Positive Breast Cancer Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Metastatic HER2 (human epidermal growth factor receptor 2)-positive breast cancer is an advanced stage of breast cancer characterized by the presence of HER2 protein overexpression. It tends to be more aggressive than other forms of cancer due to its accelerated growth and increased likelihood of spreading beyond the breast tissue. The symptoms of this illness may include a palpable lump in the breast or underarm, alterations in breast shape or size, skin dimpling, nipple changes, persistent pain, and bone fractures. As the cancer advances, it can spread to distant organs, such as the brain, bones, lungs, or liver, causing further complications. The diagnosis of metastatic HER2-positive breast cancer typically requires a combination of clinical findings and physical investigations. The healthcare provider will also perform numerous diagnostic procedures, including a mammogram or ultrasound, a biopsy of the tumor tissue to confirm HER2 positivity, and imaging studies to determine the extent of metastasis.
The increasing incidences of genetic variations in the BRCA1 and BRCA2 genes, resulting in uncontrolled growth and division of abnormal cells that originate in the breast tissue, are primarily driving the metastatic HER2-positive breast cancer market. In addition to this, the inflating utilization of innovative approaches, such as antibody-drug conjugates and immune checkpoint inhibitors, which help in harnessing the body's immune response to combat cancerous cells, is also creating a positive outlook for the market. Moreover, the widespread adoption of supportive therapies, including immunotherapies, bisphosphonates, and pain management strategies, aimed at enhancing patients' overall well-being and mitigating treatment-related complications, is further bolstering the market growth. Apart from this, the rising usage of precision medicine approaches, since they involve tailoring treatments based on the genetic makeup of the tumor, is acting as another significant growth-inducing factor. Additionally, the emerging popularity of minimally invasive procedures, such as radiofrequency ablation and cryoablation to precisely target and eliminate tumor masses in individuals suffering from the illness is also augmenting the market growth. Furthermore, the escalating application of gene-targeting treatments that aim to correct or inhibit the overexpression of the HER2 gene is expected to drive the metastatic HER2-positive breast cancer market during the forecast period.
IMARC Group's new report provides an exhaustive analysis of the metastatic HER2-positive breast cancer market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for metastatic HER2-positive breast cancer and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the metastatic HER2-positive breast cancer market in any manner.
Time Period of the Study
Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034
Countries Covered
United States
Germany
France
United Kingdom
Italy
Spain
Japan
Analysis Covered Across Each Country
Historical, current, and future epidemiology scenario
Historical, current, and future performance of the metastatic HER2-positive breast cancer market
Historical, current, and future performance of various therapeutic categories in the market
Sales of various drugs across the metastatic HER2-positive breast cancer market
Reimbursement scenario in the market
In-market and pipeline drugs
Competitive Landscape:
This report also provides a detailed analysis of the current metastatic HER2-positive breast cancer marketed drugs and late-stage pipeline drugs.
In-Market Drugs
Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance
Late-Stage Pipeline Drugs
Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance
*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.
Key Questions Answered in this Report:
Market Insights
How has the metastatic HER2-positive breast cancer market performed so far and how will it perform in the coming years?
What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
What was the country-wise size of the metastatic HER2-positive breast cancer market across the seven major markets in 2023 and what will it look like in 2034?
What is the growth rate of the metastatic HER2-positive breast cancer market across the seven major markets and what will be the expected growth over the next ten years?
What are the key unmet needs in the market?
Epidemiology Insights
What is the number of prevalent cases (?2018-2034?) of metastatic HER2-positive breast cancer across the seven major markets?
What is the number of prevalent cases (?2018-2034?) of metastatic HER2-positive breast cancer by age across the seven major markets?
What is the number of prevalent cases (?2018-2034?) of metastatic HER2-positive breast cancer by gender across the seven major markets?
How many patients are diagnosed (?2018-2034?) with metastatic HER2-positive breast cancer across the seven major markets?
What is the size of the metastatic HER2-positive breast cancer patient pool (2018-2023) across the seven major markets?
What would be the forecasted patient pool (2024-2034) across the seven major markets?
What are the key factors driving the epidemiological trend of metastatic HER2-positive breast cancer?
What will be the growth rate of patients across the seven major markets?
Metastatic HER2-Positive Breast Cancer: Current Treatment Scenario, Marketed Drugs and Emerging Therapies
What are the current marketed drugs and what are their market performance?
What are the key pipeline drugs and how are they expected to perform in the coming years?
How safe are the current marketed drugs and what are their efficacies?
How safe are the late-stage pipeline drugs and what are their efficacies?
What are the current treatment guidelines for metastatic HER2-positive breast cancer drugs across the seven major markets?
Who are the key companies in the market and what are their market shares?
What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the metastatic HER2-positive breast cancer market?
What are the key regulatory events related to the metastatic HER2-positive breast cancer market?
What is the structure of clinical trial landscape by status related to the metastatic HER2-positive breast cancer market?
What is the structure of clinical trial landscape by phase related to the metastatic HER2-positive breast cancer market?
What is the structure of clinical trial landscape by route of administration related to the metastatic HER2-positive breast cancer market?
1 PREFACE
2 SCOPE AND METHODOLOGY
2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
2.3.1 Primary Sources
2.3.2 Secondary Sources
2.4 Market Estimation
2.4.1 Bottom-Up Approach
2.4.2 Top-Down Approach
2.5 Forecasting Methodology
3 EXECUTIVE SUMMARY
4 METASTATIC HER2-POSITIVE BREAST CANCER - INTRODUCTION
4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence
5 METASTATIC HER2-POSITIVE BREAST CANCER - DISEASE OVERVIEW
5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment
6 PATIENT JOURNEY
7 METASTATIC HER2-POSITIVE BREAST CANCER - EPIDEMIOLOGY AND PATIENT POPULATION
7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
7.2.1 Epidemiology Scenario (2018-2023)
7.2.2 Epidemiology Forecast (2024-2034)
7.2.3 Epidemiology by Age (?2018-2034?)
7.2.4 Epidemiology by Gender (?2018-2034?)
7.2.5 Diagnosed Cases (?2018-2034?)
7.2.6 Patient Pool/Treated Cases (?2018-2034?)
7.3 Epidemiology Scenario - United States
7.3.1 Epidemiology Scenario (2018-2023)
7.3.2 Epidemiology Forecast (2024-2034)
7.3.3 Epidemiology by Age (?2018-2034?)
7.3.4 Epidemiology by Gender (?2018-2034?)
7.3.5 Diagnosed Cases (?2018-2034?)
7.3.6 Patient Pool/Treated Cases (?2018-2034?)
7.4 Epidemiology Scenario - Germany
7.4.1 Epidemiology Scenario (2018-2023)
7.4.2 Epidemiology Forecast (2024-2034)
7.4.3 Epidemiology by Age (?2018-2034?)
7.4.4 Epidemiology by Gender (?2018-2034?)
7.4.5 Diagnosed Cases (?2018-2034?)
7.4.6 Patient Pool/Treated Cases (?2018-2034?)
7.5 Epidemiology Scenario - France
7.5.1 Epidemiology Scenario (2018-2023)
7.5.2 Epidemiology Forecast (2024-2034)
7.5.3 Epidemiology by Age (?2018-2034?)
7.5.4 Epidemiology by Gender (?2018-2034?)
7.5.5 Diagnosed Cases (?2018-2034?)
7.5.6 Patient Pool/Treated Cases (?2018-2034?)
7.6 Epidemiology Scenario - United Kingdom
7.6.1 Epidemiology Scenario (2018-2023)
7.6.2 Epidemiology Forecast (2024-2034)
7.6.3 Epidemiology by Age (?2018-2034?)
7.6.4 Epidemiology by Gender (?2018-2034?)
7.6.5 Diagnosed Cases (?2018-2034?)
7.6.6 Patient Pool/Treated Cases (?2018-2034?)
7.7 Epidemiology Scenario - Italy
7.7.1 Epidemiology Scenario (2018-2023)
7.7.2 Epidemiology Forecast (2024-2034)
7.7.3 Epidemiology by Age (?2018-2034?)
7.7.4 Epidemiology by Gender (?2018-2034?)
7.7.5 Diagnosed Cases (?2018-2034?)
7.7.6 Patient Pool/Treated Cases (?2018-2034?)
7.8 Epidemiology Scenario - Spain
7.8.1 Epidemiology Scenario (2018-2023)
7.8.2 Epidemiology Forecast (2024-2034)
7.8.3 Epidemiology by Age (?2018-2034?)
7.8.4 Epidemiology by Gender (?2018-2034?)
7.8.5 Diagnosed Cases (?2018-2034?)
7.8.6 Patient Pool/Treated Cases (?2018-2034?)
7.9 Epidemiology Scenario - Japan
7.9.1 Epidemiology Scenario (2018-2023)
7.9.2 Epidemiology Forecast (2024-2034)
7.9.3 Epidemiology by Age (?2018-2034?)
7.9.4 Epidemiology by Gender (?2018-2034?)
7.9.5 Diagnosed Cases (?2018-2034?)
7.9.6 Patient Pool/Treated Cases (?2018-2034?)
8 METASTATIC HER2-POSITIVE BREAST CANCER - TREATMENT ALGORITHM, GUIDELINES, AND MEDICAL PRACTICES
8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm
9 METASTATIC HER2-POSITIVE BREAST CANCER - UNMET NEEDS
10 METASTATIC HER2-POSITIVE BREAST CANCER - KEY ENDPOINTS OF TREATMENT
11 METASTATIC HER2-POSITIVE BREAST CANCER - MARKETED PRODUCTS
11.1 List of Metastatic HER2-Positive Breast Cancer Marketed Drugs Across the Top 7 Markets
11.1.1 Perjeta (Pertuzumab) - Genentech
11.1.1.1 Drug Overview
11.1.1.2 Mechanism of Action
11.1.1.3 Regulatory Status
11.1.1.4 Clinical Trial Results
11.1.1.5 Sales Across Major Markets
11.1.2 Tukysa (Tucatinib) - Seagen
11.1.2.1 Drug Overview
11.1.2.2 Mechanism of Action
11.1.2.3 Regulatory Status
11.1.2.4 Clinical Trial Results
11.1.2.5 Sales Across Major Markets
11.1.3 Nerlynx (Neratinib) - Puma Biotechnology
11.1.3.1 Drug Overview
11.1.3.2 Mechanism of Action
11.1.3.3 Regulatory Status
11.1.3.4 Clinical Trial Results
11.1.3.5 Sales Across Major Markets
11.1.4 Margenzatm (Margetuximab-Cmkb) - MacroGenics
11.1.4.1 Drug Overview
11.1.4.2 Mechanism of Action
11.1.4.3 Regulatory Status
11.1.4.4 Clinical Trial Results
11.1.4.5 Sales Across Major Markets
11.1.5 Enhertu (Fam-Trastuzumab Deruxtecan-Nxki) - Daiichi Sankyo
11.1.5.1 Drug Overview
11.1.5.2 Mechanism of Action
11.1.5.3 Regulatory Status
11.1.5.4 Clinical Trial Results
11.1.5.5 Sales Across Major Markets
Kindly note that the above only represents a partial list of marketed drugs, and the complete list has been provided in the report.
12 METASTATIC HER2-POSITIVE BREAST CANCER - PIPELINE DRUGS
12.1 List of Metastatic HER2-Positive Breast Cancer Pipeline Drugs Across the Top 7 Markets
12.1.1 Pertuzumab - Genentech
12.1.1.1 Drug Overview
12.1.1.2 Mechanism of Action
12.1.1.3 Clinical Trial Results
12.1.1.4 Safety and Efficacy
12.1.1.5 Regulatory Status
12.1.2 Inavolisib - Roche Pharma
12.1.2.1 Drug Overview
12.1.2.2 Mechanism of Action
12.1.2.3 Clinical Trial Results
12.1.2.4 Safety and Efficacy
12.1.2.5 Regulatory Status
12.1.3 Giredestrant - Roche Pharma
12.1.3.1 Drug Overview
12.1.3.2 Mechanism of Action
12.1.3.3 Clinical Trial Results
12.1.3.4 Safety and Efficacy
12.1.3.5 Regulatory Status
12.1.4 ZN-A-1041 - Suzhou Zanrong Pharma
12.1.4.1 Drug Overview
12.1.4.2 Mechanism of Action
12.1.4.3 Clinical Trial Results
12.1.4.4 Safety and Efficacy
12.1.4.5 Regulatory Status
12.1.5 Palbociclib - Pfizer
12.1.5.1 Drug Overview
12.1.5.2 Mechanism of Action
12.1.5.3 Clinical Trial Results
12.1.5.4 Safety and Efficacy
12.1.5.5 Regulatory Status
Kindly note that the above only represents a partial list of pipeline drugs, and the complete list has been provided in the report.
13. METASTATIC HER2-POSITIVE BREAST CANCER - ATTRIBUTE ANALYSIS OF KEY MARKETED AND PIPELINE DRUGS
14. METASTATIC HER2-POSITIVE BREAST CANCER – CLINICAL TRIAL LANDSCAPE
14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events
15 METASTATIC HER2-POSITIVE BREAST CANCER - MARKET SCENARIO
15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
15.2.1 Metastatic HER2-Positive Breast Cancer - Market Size
15.2.1.1 Market Size (2018-2023)
15.2.1.2 Market Forecast (2024-2034)
15.2.2 Metastatic HER2-Positive Breast Cancer - Market Size by Therapies
15.2.2.1 Market Size by Therapies (2018-2023)
15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
15.3.1 Metastatic HER2-Positive Breast Cancer - Market Size
15.3.1.1 Market Size (2018-2023)
15.3.1.2 Market Forecast (2024-2034)
15.3.2 Metastatic HER2-Positive Breast Cancer - Market Size by Therapies
15.3.2.1 Market Size by Therapies (2018-2023)
15.3.2.2 Market Forecast by Therapies (2024-2034)
15.3.3 Metastatic HER2-Positive Breast Cancer - Access and Reimbursement Overview
15.4 Market Scenario - Germany
15.4.1 Metastatic HER2-Positive Breast Cancer - Market Size
15.4.1.1 Market Size (2018-2023)
15.4.1.2 Market Forecast (2024-2034)
15.4.2 Metastatic HER2-Positive Breast Cancer - Market Size by Therapies
15.4.2.1 Market Size by Therapies (2018-2023)
15.4.2.2 Market Forecast by Therapies (2024-2034)
15.4.3 Metastatic HER2-Positive Breast Cancer - Access and Reimbursement Overview
15.5 Market Scenario - France
15.5.1 Metastatic HER2-Positive Breast Cancer - Market Size
15.5.1.1 Market Size (2018-2023)
15.5.1.2 Market Forecast (2024-2034)
15.5.2 Metastatic HER2-Positive Breast Cancer - Market Size by Therapies
15.5.2.1 Market Size by Therapies (2018-2023)
15.5.2.2 Market Forecast by Therapies (2024-2034)
15.5.3 Metastatic HER2-Positive Breast Cancer - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
15.6.1 Metastatic HER2-Positive Breast Cancer - Market Size
15.6.1.1 Market Size (2018-2023)
15.6.1.2 Market Forecast (2024-2034)
15.6.2 Metastatic HER2-Positive Breast Cancer - Market Size by Therapies
15.6.2.1 Market Size by Therapies (2018-2023)
15.6.2.2 Market Forecast by Therapies (2024-2034)
15.6.3 Metastatic HER2-Positive Breast Cancer - Access and Reimbursement Overview
15.7 Market Scenario - Italy
15.7.1 Metastatic HER2-Positive Breast Cancer - Market Size
15.7.1.1 Market Size (2018-2023)
15.7.1.2 Market Forecast (2024-2034)
15.7.2 Metastatic HER2-Positive Breast Cancer - Market Size by Therapies
15.7.2.1 Market Size by Therapies (2018-2023)
15.7.2.2 Market Forecast by Therapies (2024-2034)
15.7.3 Metastatic HER2-Positive Breast Cancer - Access and Reimbursement Overview
15.8 Market Scenario - Spain
15.8.1 Metastatic HER2-Positive Breast Cancer - Market Size
15.8.1.1 Market Size (2018-2023)
15.8.1.2 Market Forecast (2024-2034)
15.8.2 Metastatic HER2-Positive Breast Cancer - Market Size by Therapies
15.8.2.1 Market Size by Therapies (2018-2023)
15.8.2.2 Market Forecast by Therapies (2024-2034)
15.8.3 Metastatic HER2-Positive Breast Cancer - Access and Reimbursement Overview
15.9 Market Scenario - Japan
15.9.1 Metastatic HER2-Positive Breast Cancer - Market Size
15.9.1.1 Market Size (2018-2023)
15.9.1.2 Market Forecast (2024-2034)
15.9.2 Metastatic HER2-Positive Breast Cancer - Market Size by Therapies
15.9.2.1 Market Size by Therapies (2018-2023)
15.9.2.2 Market Forecast by Therapies (2024-2034)
15.9.3 Metastatic HER2-Positive Breast Cancer - Access and Reimbursement Overview
16 METASTATIC HER2-POSITIVE BREAST CANCER - RECENT EVENTS AND INPUTS FROM KEY OPINION LEADERS
17 METASTATIC HER2-POSITIVE BREAST CANCER MARKET - SWOT ANALYSIS
17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats
18 METASTATIC HER2-POSITIVE BREAST CANCER MARKET – STRATEGIC RECOMMENDATIONS
19 APPENDIX
2 SCOPE AND METHODOLOGY
2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
2.3.1 Primary Sources
2.3.2 Secondary Sources
2.4 Market Estimation
2.4.1 Bottom-Up Approach
2.4.2 Top-Down Approach
2.5 Forecasting Methodology
3 EXECUTIVE SUMMARY
4 METASTATIC HER2-POSITIVE BREAST CANCER - INTRODUCTION
4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence
5 METASTATIC HER2-POSITIVE BREAST CANCER - DISEASE OVERVIEW
5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment
6 PATIENT JOURNEY
7 METASTATIC HER2-POSITIVE BREAST CANCER - EPIDEMIOLOGY AND PATIENT POPULATION
7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
7.2.1 Epidemiology Scenario (2018-2023)
7.2.2 Epidemiology Forecast (2024-2034)
7.2.3 Epidemiology by Age (?2018-2034?)
7.2.4 Epidemiology by Gender (?2018-2034?)
7.2.5 Diagnosed Cases (?2018-2034?)
7.2.6 Patient Pool/Treated Cases (?2018-2034?)
7.3 Epidemiology Scenario - United States
7.3.1 Epidemiology Scenario (2018-2023)
7.3.2 Epidemiology Forecast (2024-2034)
7.3.3 Epidemiology by Age (?2018-2034?)
7.3.4 Epidemiology by Gender (?2018-2034?)
7.3.5 Diagnosed Cases (?2018-2034?)
7.3.6 Patient Pool/Treated Cases (?2018-2034?)
7.4 Epidemiology Scenario - Germany
7.4.1 Epidemiology Scenario (2018-2023)
7.4.2 Epidemiology Forecast (2024-2034)
7.4.3 Epidemiology by Age (?2018-2034?)
7.4.4 Epidemiology by Gender (?2018-2034?)
7.4.5 Diagnosed Cases (?2018-2034?)
7.4.6 Patient Pool/Treated Cases (?2018-2034?)
7.5 Epidemiology Scenario - France
7.5.1 Epidemiology Scenario (2018-2023)
7.5.2 Epidemiology Forecast (2024-2034)
7.5.3 Epidemiology by Age (?2018-2034?)
7.5.4 Epidemiology by Gender (?2018-2034?)
7.5.5 Diagnosed Cases (?2018-2034?)
7.5.6 Patient Pool/Treated Cases (?2018-2034?)
7.6 Epidemiology Scenario - United Kingdom
7.6.1 Epidemiology Scenario (2018-2023)
7.6.2 Epidemiology Forecast (2024-2034)
7.6.3 Epidemiology by Age (?2018-2034?)
7.6.4 Epidemiology by Gender (?2018-2034?)
7.6.5 Diagnosed Cases (?2018-2034?)
7.6.6 Patient Pool/Treated Cases (?2018-2034?)
7.7 Epidemiology Scenario - Italy
7.7.1 Epidemiology Scenario (2018-2023)
7.7.2 Epidemiology Forecast (2024-2034)
7.7.3 Epidemiology by Age (?2018-2034?)
7.7.4 Epidemiology by Gender (?2018-2034?)
7.7.5 Diagnosed Cases (?2018-2034?)
7.7.6 Patient Pool/Treated Cases (?2018-2034?)
7.8 Epidemiology Scenario - Spain
7.8.1 Epidemiology Scenario (2018-2023)
7.8.2 Epidemiology Forecast (2024-2034)
7.8.3 Epidemiology by Age (?2018-2034?)
7.8.4 Epidemiology by Gender (?2018-2034?)
7.8.5 Diagnosed Cases (?2018-2034?)
7.8.6 Patient Pool/Treated Cases (?2018-2034?)
7.9 Epidemiology Scenario - Japan
7.9.1 Epidemiology Scenario (2018-2023)
7.9.2 Epidemiology Forecast (2024-2034)
7.9.3 Epidemiology by Age (?2018-2034?)
7.9.4 Epidemiology by Gender (?2018-2034?)
7.9.5 Diagnosed Cases (?2018-2034?)
7.9.6 Patient Pool/Treated Cases (?2018-2034?)
8 METASTATIC HER2-POSITIVE BREAST CANCER - TREATMENT ALGORITHM, GUIDELINES, AND MEDICAL PRACTICES
8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm
9 METASTATIC HER2-POSITIVE BREAST CANCER - UNMET NEEDS
10 METASTATIC HER2-POSITIVE BREAST CANCER - KEY ENDPOINTS OF TREATMENT
11 METASTATIC HER2-POSITIVE BREAST CANCER - MARKETED PRODUCTS
11.1 List of Metastatic HER2-Positive Breast Cancer Marketed Drugs Across the Top 7 Markets
11.1.1 Perjeta (Pertuzumab) - Genentech
11.1.1.1 Drug Overview
11.1.1.2 Mechanism of Action
11.1.1.3 Regulatory Status
11.1.1.4 Clinical Trial Results
11.1.1.5 Sales Across Major Markets
11.1.2 Tukysa (Tucatinib) - Seagen
11.1.2.1 Drug Overview
11.1.2.2 Mechanism of Action
11.1.2.3 Regulatory Status
11.1.2.4 Clinical Trial Results
11.1.2.5 Sales Across Major Markets
11.1.3 Nerlynx (Neratinib) - Puma Biotechnology
11.1.3.1 Drug Overview
11.1.3.2 Mechanism of Action
11.1.3.3 Regulatory Status
11.1.3.4 Clinical Trial Results
11.1.3.5 Sales Across Major Markets
11.1.4 Margenzatm (Margetuximab-Cmkb) - MacroGenics
11.1.4.1 Drug Overview
11.1.4.2 Mechanism of Action
11.1.4.3 Regulatory Status
11.1.4.4 Clinical Trial Results
11.1.4.5 Sales Across Major Markets
11.1.5 Enhertu (Fam-Trastuzumab Deruxtecan-Nxki) - Daiichi Sankyo
11.1.5.1 Drug Overview
11.1.5.2 Mechanism of Action
11.1.5.3 Regulatory Status
11.1.5.4 Clinical Trial Results
11.1.5.5 Sales Across Major Markets
Kindly note that the above only represents a partial list of marketed drugs, and the complete list has been provided in the report.
12 METASTATIC HER2-POSITIVE BREAST CANCER - PIPELINE DRUGS
12.1 List of Metastatic HER2-Positive Breast Cancer Pipeline Drugs Across the Top 7 Markets
12.1.1 Pertuzumab - Genentech
12.1.1.1 Drug Overview
12.1.1.2 Mechanism of Action
12.1.1.3 Clinical Trial Results
12.1.1.4 Safety and Efficacy
12.1.1.5 Regulatory Status
12.1.2 Inavolisib - Roche Pharma
12.1.2.1 Drug Overview
12.1.2.2 Mechanism of Action
12.1.2.3 Clinical Trial Results
12.1.2.4 Safety and Efficacy
12.1.2.5 Regulatory Status
12.1.3 Giredestrant - Roche Pharma
12.1.3.1 Drug Overview
12.1.3.2 Mechanism of Action
12.1.3.3 Clinical Trial Results
12.1.3.4 Safety and Efficacy
12.1.3.5 Regulatory Status
12.1.4 ZN-A-1041 - Suzhou Zanrong Pharma
12.1.4.1 Drug Overview
12.1.4.2 Mechanism of Action
12.1.4.3 Clinical Trial Results
12.1.4.4 Safety and Efficacy
12.1.4.5 Regulatory Status
12.1.5 Palbociclib - Pfizer
12.1.5.1 Drug Overview
12.1.5.2 Mechanism of Action
12.1.5.3 Clinical Trial Results
12.1.5.4 Safety and Efficacy
12.1.5.5 Regulatory Status
Kindly note that the above only represents a partial list of pipeline drugs, and the complete list has been provided in the report.
13. METASTATIC HER2-POSITIVE BREAST CANCER - ATTRIBUTE ANALYSIS OF KEY MARKETED AND PIPELINE DRUGS
14. METASTATIC HER2-POSITIVE BREAST CANCER – CLINICAL TRIAL LANDSCAPE
14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events
15 METASTATIC HER2-POSITIVE BREAST CANCER - MARKET SCENARIO
15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
15.2.1 Metastatic HER2-Positive Breast Cancer - Market Size
15.2.1.1 Market Size (2018-2023)
15.2.1.2 Market Forecast (2024-2034)
15.2.2 Metastatic HER2-Positive Breast Cancer - Market Size by Therapies
15.2.2.1 Market Size by Therapies (2018-2023)
15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
15.3.1 Metastatic HER2-Positive Breast Cancer - Market Size
15.3.1.1 Market Size (2018-2023)
15.3.1.2 Market Forecast (2024-2034)
15.3.2 Metastatic HER2-Positive Breast Cancer - Market Size by Therapies
15.3.2.1 Market Size by Therapies (2018-2023)
15.3.2.2 Market Forecast by Therapies (2024-2034)
15.3.3 Metastatic HER2-Positive Breast Cancer - Access and Reimbursement Overview
15.4 Market Scenario - Germany
15.4.1 Metastatic HER2-Positive Breast Cancer - Market Size
15.4.1.1 Market Size (2018-2023)
15.4.1.2 Market Forecast (2024-2034)
15.4.2 Metastatic HER2-Positive Breast Cancer - Market Size by Therapies
15.4.2.1 Market Size by Therapies (2018-2023)
15.4.2.2 Market Forecast by Therapies (2024-2034)
15.4.3 Metastatic HER2-Positive Breast Cancer - Access and Reimbursement Overview
15.5 Market Scenario - France
15.5.1 Metastatic HER2-Positive Breast Cancer - Market Size
15.5.1.1 Market Size (2018-2023)
15.5.1.2 Market Forecast (2024-2034)
15.5.2 Metastatic HER2-Positive Breast Cancer - Market Size by Therapies
15.5.2.1 Market Size by Therapies (2018-2023)
15.5.2.2 Market Forecast by Therapies (2024-2034)
15.5.3 Metastatic HER2-Positive Breast Cancer - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
15.6.1 Metastatic HER2-Positive Breast Cancer - Market Size
15.6.1.1 Market Size (2018-2023)
15.6.1.2 Market Forecast (2024-2034)
15.6.2 Metastatic HER2-Positive Breast Cancer - Market Size by Therapies
15.6.2.1 Market Size by Therapies (2018-2023)
15.6.2.2 Market Forecast by Therapies (2024-2034)
15.6.3 Metastatic HER2-Positive Breast Cancer - Access and Reimbursement Overview
15.7 Market Scenario - Italy
15.7.1 Metastatic HER2-Positive Breast Cancer - Market Size
15.7.1.1 Market Size (2018-2023)
15.7.1.2 Market Forecast (2024-2034)
15.7.2 Metastatic HER2-Positive Breast Cancer - Market Size by Therapies
15.7.2.1 Market Size by Therapies (2018-2023)
15.7.2.2 Market Forecast by Therapies (2024-2034)
15.7.3 Metastatic HER2-Positive Breast Cancer - Access and Reimbursement Overview
15.8 Market Scenario - Spain
15.8.1 Metastatic HER2-Positive Breast Cancer - Market Size
15.8.1.1 Market Size (2018-2023)
15.8.1.2 Market Forecast (2024-2034)
15.8.2 Metastatic HER2-Positive Breast Cancer - Market Size by Therapies
15.8.2.1 Market Size by Therapies (2018-2023)
15.8.2.2 Market Forecast by Therapies (2024-2034)
15.8.3 Metastatic HER2-Positive Breast Cancer - Access and Reimbursement Overview
15.9 Market Scenario - Japan
15.9.1 Metastatic HER2-Positive Breast Cancer - Market Size
15.9.1.1 Market Size (2018-2023)
15.9.1.2 Market Forecast (2024-2034)
15.9.2 Metastatic HER2-Positive Breast Cancer - Market Size by Therapies
15.9.2.1 Market Size by Therapies (2018-2023)
15.9.2.2 Market Forecast by Therapies (2024-2034)
15.9.3 Metastatic HER2-Positive Breast Cancer - Access and Reimbursement Overview
16 METASTATIC HER2-POSITIVE BREAST CANCER - RECENT EVENTS AND INPUTS FROM KEY OPINION LEADERS
17 METASTATIC HER2-POSITIVE BREAST CANCER MARKET - SWOT ANALYSIS
17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats
18 METASTATIC HER2-POSITIVE BREAST CANCER MARKET – STRATEGIC RECOMMENDATIONS
19 APPENDIX
