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Lymphangioleiomyomatosis Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

May 2024 | 135 pages | ID: L8C08AAB8A36EN
IMARC Group

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The 7 major lymphangioleiomyomatosis markets reached a value of US$ 87.9 Million in 2023. Looking forward, IMARC Group expects the 7MM to reach US$ 125.5 Million by 2034, exhibiting a growth rate (CAGR) of 3.29% during 2024-2034.

The lymphangioleiomyomatosis market has been comprehensively analyzed in IMARC's new report titled "Lymphangioleiomyomatosis Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Lymphangioleiomyomatosis (LAM) refers to a rare and progressive lung disease that mainly affects females of childbearing age. It is characterized by an abnormal growth of smooth muscle cells, primarily in the lungs but also involving various other organs like the kidneys and lymphatics. The symptoms of LAM can vary widely, but they often include shortness of breath, coughing, wheezing, chest pain, and recurrent lung collapses. These indications stem from the constriction and blockage of airways as well as the formation of cysts in the lungs, leading to impaired lung function and reduced oxygen exchange. The diagnosis of LAM typically involves a combination of clinical evaluation, lung function tests, high-resolution CT scans, and occasionally a lung biopsy to confirm the presence of characteristic smooth muscle cell overgrowth. Additionally, genetic testing and monitoring of kidney function may be necessary, as LAM can be associated with several other genetic disorders.

The increasing prevalence of somatic mutations in the TSC1 and TSC2 genes that cause abnormal growth of smooth muscle cells, particularly in the lungs, leading to the constriction of airways and impairing respiratory function, is primarily driving the lymphangioleiomyomatosis market. In addition to this, the inflating utilization of effective therapeutic interventions, including mTOR inhibitors, hormone therapy, and lung transplantation, aimed at managing symptoms and halting disease progression, is also creating a positive outlook for the market. Moreover, the widespread adoption of pulmonary rehabilitation programs, a comprehensive approach encompassing physical exercises and breathing techniques, to help in enhancing lung capacity, boosting physical endurance, and improving overall quality of life, is further bolstering the market growth. Apart from this, the rising usage of minimally invasive procedures, such as bronchoscopic interventions, since they can alleviate airway obstructions and promote breathing efficiency in patients, is acting as another significant growth-inducing factor. Additionally, the emerging popularity of targeted therapies, which address the specific molecular pathways and mechanisms underlying the ailment, is also augmenting the market growth. Furthermore, the escalating application of genetic therapies, where innovative strategies involving the manipulation of genetic material offer a potential avenue for correcting or compensating the defective TSC1 and TSC2 genes, is expected to drive the lymphangioleiomyomatosis market during the forecast period.

IMARC Group's new report provides an exhaustive analysis of the lymphangioleiomyomatosis market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for lymphangioleiomyomatosis and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the lymphangioleiomyomatosis market in any manner.

Time Period of the Study

Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034

Countries Covered

United States
Germany
France
United Kingdom
Italy
Spain
Japan

Analysis Covered Across Each Country

Historical, current, and future epidemiology scenario
Historical, current, and future performance of the lymphangioleiomyomatosis market
Historical, current, and future performance of various therapeutic categories in the market
Sales of various drugs across the lymphangioleiomyomatosis market
Reimbursement scenario in the market
In-market and pipeline drugs
Competitive Landscape:
This report also provides a detailed analysis of the current lymphangioleiomyomatosis marketed drugs and late-stage pipeline drugs.

In-Market Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.

Key Questions Answered in this Report:
Market Insights

How has the lymphangioleiomyomatosis market performed so far and how will it perform in the coming years?
What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
What was the country-wise size of the lymphangioleiomyomatosis market across the seven major markets in 2023 and what will it look like in 2034?
What is the growth rate of the lymphangioleiomyomatosis market across the seven major markets and what will be the expected growth over the next ten years?
What are the key unmet needs in the market?

Epidemiology Insights

What is the number of prevalent cases (2018-2034) of lymphangioleiomyomatosis across the seven major markets?
What is the number of prevalent cases (2018-2034) of lymphangioleiomyomatosis by age across the seven major markets?
What is the number of prevalent cases (2018-2034) of lymphangioleiomyomatosis by gender across the seven major markets?
How many patients are diagnosed (2018-2034) with lymphangioleiomyomatosis across the seven major markets?
What is the size of the lymphangioleiomyomatosis patient pool (2018-2023) across the seven major markets?
What would be the forecasted patient pool (2024-2034) across the seven major markets?
What are the key factors driving the epidemiological trend of lymphangioleiomyomatosis?
What will be the growth rate of patients across the seven major markets?

Lymphangioleiomyomatosis: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

What are the current marketed drugs and what are their market performance?
What are the key pipeline drugs and how are they expected to perform in the coming years?
How safe are the current marketed drugs and what are their efficacies?
How safe are the late-stage pipeline drugs and what are their efficacies?
What are the current treatment guidelines for lymphangioleiomyomatosis drugs across the seven major markets?
Who are the key companies in the market and what are their market shares?
What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the lymphangioleiomyomatosis market?
What are the key regulatory events related to the lymphangioleiomyomatosis market?
What is the structure of clinical trial landscape by status related to the lymphangioleiomyomatosis market?
What is the structure of clinical trial landscape by phase related to the lymphangioleiomyomatosis market?
What is the structure of clinical trial landscape by route of administration related to the lymphangioleiomyomatosis market?
1 PREFACE

2 SCOPE AND METHODOLOGY

2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
  2.3.1 Primary Sources
  2.3.2 Secondary Sources
2.4 Market Estimation
  2.4.1 Bottom-Up Approach
  2.4.2 Top-Down Approach
2.5 Forecasting Methodology

3 EXECUTIVE SUMMARY

4 LYMPHANGIOLEIOMYOMATOSIS - INTRODUCTION

4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence

5 LYMPHANGIOLEIOMYOMATOSIS - DISEASE OVERVIEW

5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment

6 PATIENT JOURNEY

7 LYMPHANGIOLEIOMYOMATOSIS - EPIDEMIOLOGY AND PATIENT POPULATION

7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
  7.2.1 Epidemiology Scenario (2018-2023)
  7.2.2 Epidemiology Forecast (2024-2034)
  7.2.3 Epidemiology by Age (2018-2034)
  7.2.4 Epidemiology by Gender (2018-2034)
  7.2.5 Diagnosed Cases (2018-2034)
  7.2.6 Patient Pool/Treated Cases (2018-2034)
7.3 Epidemiology Scenario - United States
  7.3.1 Epidemiology Scenario (2018-2023)
  7.3.2 Epidemiology Forecast (2024-2034)
  7.3.3 Epidemiology by Age (2018-2034)
  7.3.4 Epidemiology by Gender (2018-2034)
  7.3.5 Diagnosed Cases (2018-2034)
  7.3.6 Patient Pool/Treated Cases (2018-2034)
7.4 Epidemiology Scenario - Germany
  7.4.1 Epidemiology Scenario (2018-2023)
  7.4.2 Epidemiology Forecast (2024-2034)
  7.4.3 Epidemiology by Age (2018-2034)
  7.4.4 Epidemiology by Gender (2018-2034)
  7.4.5 Diagnosed Cases (2018-2034)
  7.4.6 Patient Pool/Treated Cases (2018-2034)
7.5 Epidemiology Scenario - France
  7.5.1 Epidemiology Scenario (2018-2023)
  7.5.2 Epidemiology Forecast (2024-2034)
  7.5.3 Epidemiology by Age (2018-2034)
  7.5.4 Epidemiology by Gender (2018-2034)
  7.5.5 Diagnosed Cases (2018-2034)
  7.5.6 Patient Pool/Treated Cases (2018-2034)
7.6 Epidemiology Scenario - United Kingdom
  7.6.1 Epidemiology Scenario (2018-2023)
  7.6.2 Epidemiology Forecast (2024-2034)
  7.6.3 Epidemiology by Age (2018-2034)
  7.6.4 Epidemiology by Gender (2018-2034)
  7.6.5 Diagnosed Cases (2018-2034)
  7.6.6 Patient Pool/Treated Cases (2018-2034)
7.7 Epidemiology Scenario - Italy
  7.7.1 Epidemiology Scenario (2018-2023)
  7.7.2 Epidemiology Forecast (2024-2034)
  7.7.3 Epidemiology by Age (2018-2034)
  7.7.4 Epidemiology by Gender (2018-2034)
  7.7.5 Diagnosed Cases (2018-2034)
  7.7.6 Patient Pool/Treated Cases (2018-2034)
7.8 Epidemiology Scenario - Spain
  7.8.1 Epidemiology Scenario (2018-2023)
  7.8.2 Epidemiology Forecast (2024-2034)
  7.8.3 Epidemiology by Age (2018-2034)
  7.8.4 Epidemiology by Gender (2018-2034)
  7.8.5 Diagnosed Cases (2018-2034)
  7.8.6 Patient Pool/Treated Cases (2018-2034)
7.9 Epidemiology Scenario - Japan
  7.9.1 Epidemiology Scenario (2018-2023)
  7.9.2 Epidemiology Forecast (2024-2034)
  7.9.3 Epidemiology by Age (2018-2034)
  7.9.4 Epidemiology by Gender (2018-2034)
  7.9.5 Diagnosed Cases (2018-2034)
  7.9.6 Patient Pool/Treated Cases (2018-2034)

8 LYMPHANGIOLEIOMYOMATOSIS - TREATMENT ALGORITHM, GUIDELINES, AND MEDICAL PRACTICES

8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm

9 LYMPHANGIOLEIOMYOMATOSIS - UNMET NEEDS

10 LYMPHANGIOLEIOMYOMATOSIS - KEY ENDPOINTS OF TREATMENT

11 LYMPHANGIOLEIOMYOMATOSIS - MARKETED PRODUCTS

11.1 List of Lymphangioleiomyomatosis Marketed Drugs Across the Top 7 Markets
  11.1.1 Rapamune (Sirolimus) – Pfizer
    11.1.1.1 Drug Overview
    11.1.1.2 Mechanism of Action
    11.1.1.3 Regulatory Status
    11.1.1.4 Clinical Trial Results
    11.1.1.5 Sales Across Major Markets
Kindly note that the above only represents a partial list of marketed drugs, and the complete list has been provided in the report.

12 LYMPHANGIOLEIOMYOMATOSIS - PIPELINE DRUGS

12.1 List of Lymphangioleiomyomatosis Pipeline Drugs Across the Top 7 Markets
  12.1.1 Drug Name – Company Name
    12.1.1.1 Drug Overview
    12.1.1.2 Mechanism of Action
    12.1.1.3 Clinical Trial Results
    12.1.1.4 Safety and Efficacy
    12.1.1.5 Regulatory Status
Kindly note that the complete list of pipeline drugs has been provided in the report.

13. LYMPHANGIOLEIOMYOMATOSIS - ATTRIBUTE ANALYSIS OF KEY MARKETED AND PIPELINE DRUGS

14. LYMPHANGIOLEIOMYOMATOSIS – CLINICAL TRIAL LANDSCAPE

14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events

15 LYMPHANGIOLEIOMYOMATOSIS - MARKET SCENARIO

15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
  15.2.1 Lymphangioleiomyomatosis - Market Size
    15.2.1.1 Market Size (2018-2023)
    15.2.1.2 Market Forecast (2024-2034)
  15.2.2 Lymphangioleiomyomatosis - Market Size by Therapies
    15.2.2.1 Market Size by Therapies (2018-2023)
    15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
  15.3.1 Lymphangioleiomyomatosis - Market Size
    15.3.1.1 Market Size (2018-2023)
    15.3.1.2 Market Forecast (2024-2034)
  15.3.2 Lymphangioleiomyomatosis - Market Size by Therapies
    15.3.2.1 Market Size by Therapies (2018-2023)
    15.3.2.2 Market Forecast by Therapies (2024-2034)
  15.3.3 Lymphangioleiomyomatosis - Access and Reimbursement Overview
15.4 Market Scenario - Germany
  15.4.1 Lymphangioleiomyomatosis - Market Size
    15.4.1.1 Market Size (2018-2023)
    15.4.1.2 Market Forecast (2024-2034)
  15.4.2 Lymphangioleiomyomatosis - Market Size by Therapies
    15.4.2.1 Market Size by Therapies (2018-2023)
    15.4.2.2 Market Forecast by Therapies (2024-2034)
  15.4.3 Lymphangioleiomyomatosis - Access and Reimbursement Overview
15.5 Market Scenario - France
  15.5.1 Lymphangioleiomyomatosis - Market Size
    15.5.1.1 Market Size (2018-2023)
    15.5.1.2 Market Forecast (2024-2034)
  15.5.2 Lymphangioleiomyomatosis - Market Size by Therapies
    15.5.2.1 Market Size by Therapies (2018-2023)
    15.5.2.2 Market Forecast by Therapies (2024-2034)
  15.5.3 Lymphangioleiomyomatosis - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
  15.6.1 Lymphangioleiomyomatosis - Market Size
    15.6.1.1 Market Size (2018-2023)
    15.6.1.2 Market Forecast (2024-2034)
  15.6.2 Lymphangioleiomyomatosis - Market Size by Therapies
    15.6.2.1 Market Size by Therapies (2018-2023)
    15.6.2.2 Market Forecast by Therapies (2024-2034)
  15.6.3 Lymphangioleiomyomatosis - Access and Reimbursement Overview
15.7 Market Scenario - Italy
  15.7.1 Lymphangioleiomyomatosis - Market Size
    15.7.1.1 Market Size (2018-2023)
    15.7.1.2 Market Forecast (2024-2034)
  15.7.2 Lymphangioleiomyomatosis - Market Size by Therapies
    15.7.2.1 Market Size by Therapies (2018-2023)
    15.7.2.2 Market Forecast by Therapies (2024-2034)
  15.7.3 Lymphangioleiomyomatosis - Access and Reimbursement Overview
15.8 Market Scenario - Spain
  15.8.1 Lymphangioleiomyomatosis - Market Size
    15.8.1.1 Market Size (2018-2023)
    15.8.1.2 Market Forecast (2024-2034)
  15.8.2 Lymphangioleiomyomatosis - Market Size by Therapies
    15.8.2.1 Market Size by Therapies (2018-2023)
    15.8.2.2 Market Forecast by Therapies (2024-2034)
  15.8.3 Lymphangioleiomyomatosis - Access and Reimbursement Overview
15.9 Market Scenario - Japan
  15.9.1 Lymphangioleiomyomatosis - Market Size
    15.9.1.1 Market Size (2018-2023)
    15.9.1.2 Market Forecast (2024-2034)
  15.9.2 Lymphangioleiomyomatosis - Market Size by Therapies
    15.9.2.1 Market Size by Therapies (2018-2023)
    15.9.2.2 Market Forecast by Therapies (2024-2034)
  15.9.3 Lymphangioleiomyomatosis - Access and Reimbursement Overview

16 LYMPHANGIOLEIOMYOMATOSIS - RECENT EVENTS AND INPUTS FROM KEY OPINION LEADERS

17 LYMPHANGIOLEIOMYOMATOSIS MARKET - SWOT ANALYSIS

17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats

18 LYMPHANGIOLEIOMYOMATOSIS MARKET – STRATEGIC RECOMMENDATIONS

19 APPENDIX


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