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Lenegre’s Disease Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

May 2024 | 140 pages | ID: L5BAD67FE168EN
IMARC Group

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The 7 major Lenegre’s disease markets reached a value of US$ 782.9 Million in 2023. Looking forward, IMARC Group expects the 7MM to reach US$ 1,569.6 Million by 2034, exhibiting a growth rate (CAGR) of 6.53% during 2024-2034.

The Lenegre’s disease market has been comprehensively analyzed in IMARC's new report titled "Lenegre’s Disease Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Lenegre's disease is a rare cardiac disorder characterized by abnormalities in the electrical conduction system of the heart. This condition primarily affects the heart's ability to transmit electrical signals efficiently, leading to various symptoms. The common indications of the disorder often manifest as bradycardia (abnormally slow heart rate), fainting or dizziness, and unexplained episodes of heart palpitations. Individuals suffering from this ailment may also experience shortness of breath, fatigue, and chest discomfort due to impaired heart function. As the illness progresses, patients may be at an enhanced risk of developing more severe complications, such as heart failure and arrhythmias. The diagnosis of Lenegre's disease involves a thorough evaluation of the medical history, a physical examination, and electrocardiogram (ECG) testing. The ECG typically shows specific patterns indicative of conduction abnormalities. In some cases, numerous other cardiac tests, such as Holter monitoring or electrophysiological studies, may be required to confirm the diagnosis and evaluate the severity of the condition.

The escalating prevalence of cardiac-related somatic mutations in the SCN5A gene, which lead to abnormalities in the cardiac sodium channels, affecting the electrical conduction system of the heart and causing bradycardia or cardiac block, is primarily driving the Lenegre's disease market. In addition to this, the inflating demand for effective medications, including beta-blockers, calcium channel blockers, pacemakers, etc., to manage the condition and mitigate further complications is also creating a positive outlook for the market. Moreover, the increasing adoption of cardiac rehabilitation programs and exercise therapies is bolstering the market growth. These interventions aid in strengthening the heart muscles, improving cardiovascular function, and enhancing overall heart health, thus proving to be crucial for individuals suffering from the condition. Apart from this, the rising usage of catheter ablation procedures, which involve selectively destroying the abnormal cardiac conduction pathways through controlled radiofrequency or cryoablation, is also acting as another significant growth-inducing factor. Additionally, the emerging popularity of gene therapy, since it works by introducing functional genetic material into affected cardiac cells to correct or replace the malfunctioning genes responsible for the condition, thereby offering a transformative approach to treatment, is expected to drive the Lenegre's disease market during the forecast period.

IMARC Group's new report provides an exhaustive analysis of the Lenegre’s disease market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for Lenegre’s disease and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the Lenegre’s disease market in any manner.

Time Period of the Study

Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034

Countries Covered

United States
Germany
France
United Kingdom
Italy
Spain
Japan

Analysis Covered Across Each Country

Historical, current, and future epidemiology scenario
Historical, current, and future performance of the Lenegre’s disease market
Historical, current, and future performance of various therapeutic categories in the market
Sales of various drugs across the Lenegre’s disease market
Reimbursement scenario in the market
In-market and pipeline drugs
Competitive Landscape:
This report also provides a detailed analysis of the current Lenegre’s disease marketed drugs and late-stage pipeline drugs.

In-Market Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance
Key Questions Answered in this Report:
Market Insights

How has the Lenegre’s disease market performed so far and how will it perform in the coming years?
What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
What was the country-wise size of the Lenegre’s disease market across the seven major markets in 2023 and what will it look like in 2034?
What is the growth rate of the Lenegre’s disease market across the seven major markets and what will be the expected growth over the next ten years?
What are the key unmet needs in the market?

Epidemiology Insights

What is the number of prevalent cases (2018-2034) of Lenegre’s disease across the seven major markets?
What is the number of prevalent cases (2018-2034) of Lenegre’s disease by age across the seven major markets?
What is the number of prevalent cases (2018-2034) of Lenegre’s disease by gender across the seven major markets?
How many patients are diagnosed (2018-2034) with Lenegre’s disease across the seven major markets?
What is the size of the Lenegre’s disease patient pool (2018-2023) across the seven major markets?
What would be the forecasted patient pool (2024-2034) across the seven major markets?
What are the key factors driving the epidemiological trend of Lenegre’s disease?
What will be the growth rate of patients across the seven major markets?

Lenegre’s Disease: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

What are the current marketed drugs and what are their market performance?
What are the key pipeline drugs and how are they expected to perform in the coming years?
How safe are the current marketed drugs and what are their efficacies?
How safe are the late-stage pipeline drugs and what are their efficacies?
What are the current treatment guidelines for Lenegre’s disease drugs across the seven major markets?
Who are the key companies in the market and what are their market shares?
What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the Lenegre’s disease market?
What are the key regulatory events related to the Lenegre’s disease market?
What is the structure of clinical trial landscape by status related to the Lenegre’s disease market?
What is the structure of clinical trial landscape by phase related to the Lenegre’s disease market?
What is the structure of clinical trial landscape by route of administration related to the Lenegre’s disease market?
1 PREFACE

2 SCOPE AND METHODOLOGY

2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
  2.3.1 Primary Sources
  2.3.2 Secondary Sources
2.4 Market Estimation
  2.4.1 Bottom-Up Approach
  2.4.2 Top-Down Approach
2.5 Forecasting Methodology

3 EXECUTIVE SUMMARY

4 LENEGRE’S DISEASE - INTRODUCTION

4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence

5 LENEGRE’S DISEASE - DISEASE OVERVIEW

5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment

6 PATIENT JOURNEY

7 LENEGRE’S DISEASE - EPIDEMIOLOGY AND PATIENT POPULATION

7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
  7.2.1 Epidemiology Scenario (2018-2023)
  7.2.2 Epidemiology Forecast (2024-2034)
  7.2.3 Epidemiology by Age (?????2018-2034?)
  7.2.4 Epidemiology by Gender (?????2018-2034?)
  7.2.5 Diagnosed Cases (?????2018-2034?)
  7.2.6 Patient Pool/Treated Cases (?????2018-2034?)
7.3 Epidemiology Scenario - United States
  7.3.1 Epidemiology Scenario (2018-2023)
  7.3.2 Epidemiology Forecast (2024-2034)
  7.3.3 Epidemiology by Age (?????2018-2034?)
  7.3.4 Epidemiology by Gender (?????2018-2034?)
  7.3.5 Diagnosed Cases (?????2018-2034?)
  7.3.6 Patient Pool/Treated Cases (?????2018-2034?)
7.4 Epidemiology Scenario - Germany
  7.4.1 Epidemiology Scenario (2018-2023)
  7.4.2 Epidemiology Forecast (2024-2034)
  7.4.3 Epidemiology by Age (?????2018-2034?)
  7.4.4 Epidemiology by Gender (?????2018-2034?)
  7.4.5 Diagnosed Cases (?????2018-2034?)
  7.4.6 Patient Pool/Treated Cases (?????2018-2034?)
7.5 Epidemiology Scenario - France
  7.5.1 Epidemiology Scenario (2018-2023)
  7.5.2 Epidemiology Forecast (2024-2034)
  7.5.3 Epidemiology by Age (?????2018-2034?)
  7.5.4 Epidemiology by Gender (?????2018-2034?)
  7.5.5 Diagnosed Cases (?????2018-2034?)
  7.5.6 Patient Pool/Treated Cases (?????2018-2034?)
7.6 Epidemiology Scenario - United Kingdom
  7.6.1 Epidemiology Scenario (2018-2023)
  7.6.2 Epidemiology Forecast (2024-2034)
  7.6.3 Epidemiology by Age (?????2018-2034?)
  7.6.4 Epidemiology by Gender (?????2018-2034?)
  7.6.5 Diagnosed Cases (?????2018-2034?)
  7.6.6 Patient Pool/Treated Cases (?????2018-2034?)
7.7 Epidemiology Scenario - Italy
  7.7.1 Epidemiology Scenario (2018-2023)
  7.7.2 Epidemiology Forecast (2024-2034)
  7.7.3 Epidemiology by Age (?????2018-2034?)
  7.7.4 Epidemiology by Gender (?????2018-2034?)
  7.7.5 Diagnosed Cases (?????2018-2034?)
  7.7.6 Patient Pool/Treated Cases (?????2018-2034?)
7.8 Epidemiology Scenario - Spain
  7.8.1 Epidemiology Scenario (2018-2023)
  7.8.2 Epidemiology Forecast (2024-2034)
  7.8.3 Epidemiology by Age (?????2018-2034?)
  7.8.4 Epidemiology by Gender (?????2018-2034?)
  7.8.5 Diagnosed Cases (?????2018-2034?)
  7.8.6 Patient Pool/Treated Cases (?????2018-2034?)
7.9 Epidemiology Scenario - Japan
  7.9.1 Epidemiology Scenario (2018-2023)
  7.9.2 Epidemiology Forecast (2024-2034)
  7.9.3 Epidemiology by Age (?????2018-2034?)
  7.9.4 Epidemiology by Gender (?????2018-2034?)
  7.9.5 Diagnosed Cases (?????2018-2034?)
  7.9.6 Patient Pool/Treated Cases (?????2018-2034?)

8 LENEGRE’S DISEASE - TREATMENT ALGORITHM, GUIDELINES, AND MEDICAL PRACTICES

8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm

9 LENEGRE’S DISEASE - UNMET NEEDS

10 LENEGRE’S DISEASE - KEY ENDPOINTS OF TREATMENT

11 LENEGRE’S DISEASE - MARKETED PRODUCTS

11.1 List of Lenegre’s Disease Marketed Drugs Across the Top 7 Markets
  11.1.1 Drug Name – Company Name
    11.1.1.1 Drug Overview
    11.1.1.2 Mechanism of Action
    11.1.1.3 Regulatory Status
    11.1.1.4 Clinical Trial Results
    11.1.1.5 Sales Across Major Markets
Kindly note that the complete list of marketed drugs has been provided in the report.

12 LENEGRE’S DISEASE - PIPELINE DRUGS

12.1 List of Lenegre’s Disease Pipeline Drugs Across the Top 7 Markets
  12.1.1 Drug Name – Company Name
    12.1.1.1 Drug Overview
    12.1.1.2 Mechanism of Action
    12.1.1.3 Clinical Trial Results
    12.1.1.4 Safety and Efficacy
    12.1.1.5 Regulatory Status
Kindly note that the complete list of pipeline drugs has been provided in the report.

13. LENEGRE’S DISEASE - ATTRIBUTE ANALYSIS OF KEY MARKETED AND PIPELINE DRUGS

14. LENEGRE’S DISEASE – CLINICAL TRIAL LANDSCAPE

14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events

15 LENEGRE’S DISEASE - MARKET SCENARIO

15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
  15.2.1 Lenegre’s Disease - Market Size
    15.2.1.1 Market Size (2018-2023)
    15.2.1.2 Market Forecast (2024-2034)
  15.2.2 Lenegre’s Disease - Market Size by Therapies
    15.2.2.1 Market Size by Therapies (2018-2023)
    15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
  15.3.1 Lenegre’s Disease - Market Size
    15.3.1.1 Market Size (2018-2023)
    15.3.1.2 Market Forecast (2024-2034)
  15.3.2 Lenegre’s Disease - Market Size by Therapies
    15.3.2.1 Market Size by Therapies (2018-2023)
    15.3.2.2 Market Forecast by Therapies (2024-2034)
  15.3.3 Lenegre’s Disease - Access and Reimbursement Overview
15.4 Market Scenario - Germany
  15.4.1 Lenegre’s Disease - Market Size
    15.4.1.1 Market Size (2018-2023)
    15.4.1.2 Market Forecast (2024-2034)
  15.4.2 Lenegre’s Disease - Market Size by Therapies
    15.4.2.1 Market Size by Therapies (2018-2023)
    15.4.2.2 Market Forecast by Therapies (2024-2034)
  15.4.3 Lenegre’s Disease - Access and Reimbursement Overview
15.5 Market Scenario - France
  15.5.1 Lenegre’s Disease - Market Size
    15.5.1.1 Market Size (2018-2023)
    15.5.1.2 Market Forecast (2024-2034)
  15.5.2 Lenegre’s Disease - Market Size by Therapies
    15.5.2.1 Market Size by Therapies (2018-2023)
    15.5.2.2 Market Forecast by Therapies (2024-2034)
  15.5.3 Lenegre’s Disease - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
  15.6.1 Lenegre’s Disease - Market Size
    15.6.1.1 Market Size (2018-2023)
    15.6.1.2 Market Forecast (2024-2034)
  15.6.2 Lenegre’s Disease - Market Size by Therapies
    15.6.2.1 Market Size by Therapies (2018-2023)
    15.6.2.2 Market Forecast by Therapies (2024-2034)
  15.6.3 Lenegre’s Disease - Access and Reimbursement Overview
15.7 Market Scenario - Italy
  15.7.1 Lenegre’s Disease - Market Size
    15.7.1.1 Market Size (2018-2023)
    15.7.1.2 Market Forecast (2024-2034)
  15.7.2 Lenegre’s Disease - Market Size by Therapies
    15.7.2.1 Market Size by Therapies (2018-2023)
    15.7.2.2 Market Forecast by Therapies (2024-2034)
  15.7.3 Lenegre’s Disease - Access and Reimbursement Overview
15.8 Market Scenario - Spain
  15.8.1 Lenegre’s Disease - Market Size
    15.8.1.1 Market Size (2018-2023)
    15.8.1.2 Market Forecast (2024-2034)
  15.8.2 Lenegre’s Disease - Market Size by Therapies
    15.8.2.1 Market Size by Therapies (2018-2023)
    15.8.2.2 Market Forecast by Therapies (2024-2034)
  15.8.3 Lenegre’s Disease - Access and Reimbursement Overview
15.9 Market Scenario - Japan
  15.9.1 Lenegre’s Disease - Market Size
    15.9.1.1 Market Size (2018-2023)
    15.9.1.2 Market Forecast (2024-2034)
  15.9.2 Lenegre’s Disease - Market Size by Therapies
    15.9.2.1 Market Size by Therapies (2018-2023)
    15.9.2.2 Market Forecast by Therapies (2024-2034)
  15.9.3 Lenegre’s Disease - Access and Reimbursement Overview

16 LENEGRE’S DISEASE - RECENT EVENTS AND INPUTS FROM KEY OPINION LEADERS

17 LENEGRE’S DISEASE MARKET - SWOT ANALYSIS

17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats

18 LENEGRE’S DISEASE MARKET – STRATEGIC RECOMMENDATIONS

19 APPENDIX


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