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Lamellar Ichthyosis Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

May 2024 | 136 pages | ID: L84944B592DCEN
IMARC Group

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The 7 major lamellar ichthyosis markets reached a value of US$ 5.1 Million in 2023. Looking forward, IMARC Group expects the 7MM to reach US$ 8.1 Million by 2034, exhibiting a growth rate (CAGR) of 4.3% during 2024-2034.

The lamellar ichthyosis market has been comprehensively analyzed in IMARC's new report titled "Lamellar Ichthyosis Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Lamellar ichthyosis is a rare and inherited skin disorder that falls under the broader category of ichthyosis, which refers to a group of genetic conditions characterized by dry, scaly skin. This particular type is caused by mutations in the gene responsible for forming a protein called transglutaminase-1, leading to the abnormal development of the skin's protective barrier. The symptoms of the ailment typically manifest at birth or within the first few weeks of life. Individuals suffering from the illness may present with thick, plate-like scales covering large areas of their body, often resembling fish scales. The skin can be dry, rough, and prone to cracking, which can cause discomfort and susceptibility to infections. Moreover, these scales may affect the patient's range of motion and lead to restricted movement. The diagnosis of lamellar ichthyosis involves a thorough examination of the skin and family history analysis. Skin biopsies and genetic testing are also crucial steps in confirming the condition.

The rising prevalence of somatic mutations in the TGM1 gene, which result in the impaired production of the enzyme transglutaminase-1, leading to the buildup of scale-like skin, particularly affecting the face and body regions, is primarily driving the lamellar ichthyosis market. In addition to this, the escalating adoption of numerous effective medications, including emollients, keratolytics, retinoids, etc., to alleviate symptoms of the ailment and enhance skin barrier function is fostering a positive outlook for the market. Moreover, the widespread implementation of physical and occupational therapies to increase treatment response is further bolstering the market growth. These therapies play a crucial role in managing the condition by promoting mobility, improving limb function, and enhancing overall motor skills. Apart from this, the increasing utilization of phototherapy, since it involves exposing the affected skin to controlled levels of ultraviolet light, thereby boosting the quality of life for individuals suffering from the illness, is acting as another significant growth-inducing factor. Additionally, the emerging popularity of gene therapy that works by introducing functional genetic material to correct or replace the faulty TGM1 gene responsible for the disease, providing long-term relief to patients, is expected to drive the lamellar ichthyosis market during the forecast period.

IMARC Group's new report provides an exhaustive analysis of the lamellar ichthyosis market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for lamellar ichthyosis and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the lamellar ichthyosis market in any manner.

Time Period of the Study

Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034

Countries Covered

United States
Germany
France
United Kingdom
Italy
Spain
Japan

Analysis Covered Across Each Country

Historical, current, and future epidemiology scenario
Historical, current, and future performance of the lamellar ichthyosis market
Historical, current, and future performance of various therapeutic categories in the market
Sales of various drugs across the lamellar ichthyosis market
Reimbursement scenario in the market
In-market and pipeline drugs
Competitive Landscape:
This report also provides a detailed analysis of the current lamellar ichthyosis marketed drugs and late-stage pipeline drugs.

In-Market Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance
Key Questions Answered in this Report:
Market Insights

How has the lamellar ichthyosis market performed so far and how will it perform in the coming years?
What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
What was the country-wise size of the lamellar ichthyosis market across the seven major markets in 2023 and what will it look like in 2034?
What is the growth rate of the lamellar ichthyosis market across the seven major markets and what will be the expected growth over the next ten years?
What are the key unmet needs in the market?

Epidemiology Insights

What is the number of prevalent cases (2018-2034) of lamellar ichthyosis across the seven major markets?
What is the number of prevalent cases (2018-2034) of lamellar ichthyosis by age across the seven major markets?
What is the number of prevalent cases (2018-2034) of lamellar ichthyosis by gender across the seven major markets?
How many patients are diagnosed (2018-2034) with lamellar ichthyosis across the seven major markets?
What is the size of the lamellar ichthyosis patient pool (2018-2023) across the seven major markets?
What would be the forecasted patient pool (2024-2034) across the seven major markets?
What are the key factors driving the epidemiological trend of lamellar ichthyosis?
What will be the growth rate of patients across the seven major markets?

Lamellar Ichthyosis: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

What are the current marketed drugs and what are their market performance?
What are the key pipeline drugs and how are they expected to perform in the coming years?
How safe are the current marketed drugs and what are their efficacies?
How safe are the late-stage pipeline drugs and what are their efficacies?
What are the current treatment guidelines for lamellar ichthyosis drugs across the seven major markets?
Who are the key companies in the market and what are their market shares?
What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the lamellar ichthyosis market?
What are the key regulatory events related to the lamellar ichthyosis market?
What is the structure of clinical trial landscape by status related to the lamellar ichthyosis market?
What is the structure of clinical trial landscape by phase related to the lamellar ichthyosis market?
What is the structure of clinical trial landscape by route of administration related to the lamellar ichthyosis market?
?1 Preface

2 SCOPE AND METHODOLOGY

2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
  2.3.1 Primary Sources
  2.3.2 Secondary Sources
2.4 Market Estimation
  2.4.1 Bottom-Up Approach
  2.4.2 Top-Down Approach
2.5 Forecasting Methodology

3 EXECUTIVE SUMMARY

4 LAMELLAR ICHTHYOSIS - INTRODUCTION

4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence

5 LAMELLAR ICHTHYOSIS - DISEASE OVERVIEW

5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment

6 PATIENT JOURNEY

7 LAMELLAR ICHTHYOSIS - EPIDEMIOLOGY AND PATIENT POPULATION

7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
  7.2.1 Epidemiology Scenario (2018-2023)
  7.2.2 Epidemiology Forecast (2024-2034)
  7.2.3 Epidemiology by Age (2018-2034)
  7.2.4 Epidemiology by Gender (2018-2034)
  7.2.5 Diagnosed Cases (2018-2034)
  7.2.6 Patient Pool/Treated Cases (2018-2034)
7.3 Epidemiology Scenario - United States
  7.3.1 Epidemiology Scenario (2018-2023)
  7.3.2 Epidemiology Forecast (2024-2034)
  7.3.3 Epidemiology by Age (2018-2034)
  7.3.4 Epidemiology by Gender (2018-2034)
  7.3.5 Diagnosed Cases (2018-2034)
  7.3.6 Patient Pool/Treated Cases (2018-2034)
7.4 Epidemiology Scenario - Germany
  7.4.1 Epidemiology Scenario (2018-2023)
  7.4.2 Epidemiology Forecast (2024-2034)
  7.4.3 Epidemiology by Age (2018-2034)
  7.4.4 Epidemiology by Gender (2018-2034)
  7.4.5 Diagnosed Cases (2018-2034)
  7.4.6 Patient Pool/Treated Cases (2018-2034)
7.5 Epidemiology Scenario - France
  7.5.1 Epidemiology Scenario (2018-2023)
  7.5.2 Epidemiology Forecast (2024-2034)
  7.5.3 Epidemiology by Age (2018-2034)
  7.5.4 Epidemiology by Gender (2018-2034)
  7.5.5 Diagnosed Cases (2018-2034)
  7.5.6 Patient Pool/Treated Cases (2018-2034)
7.6 Epidemiology Scenario - United Kingdom
  7.6.1 Epidemiology Scenario (2018-2023)
  7.6.2 Epidemiology Forecast (2024-2034)
  7.6.3 Epidemiology by Age (2018-2034)
  7.6.4 Epidemiology by Gender (2018-2034)
  7.6.5 Diagnosed Cases (2018-2034)
  7.6.6 Patient Pool/Treated Cases (2018-2034)
7.7 Epidemiology Scenario - Italy
  7.7.1 Epidemiology Scenario (2018-2023)
  7.7.2 Epidemiology Forecast (2024-2034)
  7.7.3 Epidemiology by Age (2018-2034)
  7.7.4 Epidemiology by Gender (2018-2034)
  7.7.5 Diagnosed Cases (2018-2034)
  7.7.6 Patient Pool/Treated Cases (2018-2034)
7.8 Epidemiology Scenario - Spain
  7.8.1 Epidemiology Scenario (2018-2023)
  7.8.2 Epidemiology Forecast (2024-2034)
  7.8.3 Epidemiology by Age (2018-2034)
  7.8.4 Epidemiology by Gender (2018-2034)
  7.8.5 Diagnosed Cases (2018-2034)
  7.8.6 Patient Pool/Treated Cases (2018-2034)
7.9 Epidemiology Scenario - Japan
  7.9.1 Epidemiology Scenario (2018-2023)
  7.9.2 Epidemiology Forecast (2024-2034)
  7.9.3 Epidemiology by Age (2018-2034)
  7.9.4 Epidemiology by Gender (2018-2034)
  7.9.5 Diagnosed Cases (2018-2034)
  7.9.6 Patient Pool/Treated Cases (2018-2034)

8 LAMELLAR ICHTHYOSIS - TREATMENT ALGORITHM, GUIDELINES, AND MEDICAL PRACTICES

8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm

9 LAMELLAR ICHTHYOSIS - UNMET NEEDS

10 LAMELLAR ICHTHYOSIS - KEY ENDPOINTS OF TREATMENT

11 LAMELLAR ICHTHYOSIS - MARKETED PRODUCTS

11.1 List of Lamellar Ichthyosis Marketed Drugs Across the Top 7 Markets
  11.1.1 Drug Name – Company Name
    11.1.1.1 Drug Overview
    11.1.1.2 Mechanism of Action
    11.1.1.3 Regulatory Status
    11.1.1.4 Clinical Trial Results
    11.1.1.5 Sales Across Major Markets
Kindly note that the complete list of marketed drugs has been provided in the report.

12 LAMELLAR ICHTHYOSIS - PIPELINE DRUGS

12.1 List of Lamellar Ichthyosis Pipeline Drugs Across the Top 7 Markets
  12.1.1 Drug Name – Company Name
    12.1.1.1 Drug Overview
    12.1.1.2 Mechanism of Action
    12.1.1.3 Clinical Trial Results
    12.1.1.4 Safety and Efficacy
    12.1.1.5 Regulatory Status
Kindly note that the complete list of pipeline drugs has been provided in the report.

13. LAMELLAR ICHTHYOSIS - ATTRIBUTE ANALYSIS OF KEY MARKETED AND PIPELINE DRUGS

14. LAMELLAR ICHTHYOSIS – CLINICAL TRIAL LANDSCAPE

14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events

15 LAMELLAR ICHTHYOSIS - MARKET SCENARIO

15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
  15.2.1 Lamellar Ichthyosis - Market Size
    15.2.1.1 Market Size (2018-2023)
    15.2.1.2 Market Forecast (2024-2034)
  15.2.2 Lamellar Ichthyosis - Market Size by Therapies
    15.2.2.1 Market Size by Therapies (2018-2023)
    15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
  15.3.1 Lamellar Ichthyosis - Market Size
    15.3.1.1 Market Size (2018-2023)
    15.3.1.2 Market Forecast (2024-2034)
  15.3.2 Lamellar Ichthyosis - Market Size by Therapies
    15.3.2.1 Market Size by Therapies (2018-2023)
    15.3.2.2 Market Forecast by Therapies (2024-2034)
  15.3.3 Lamellar Ichthyosis - Access and Reimbursement Overview
15.4 Market Scenario - Germany
  15.4.1 Lamellar Ichthyosis - Market Size
    15.4.1.1 Market Size (2018-2023)
    15.4.1.2 Market Forecast (2024-2034)
  15.4.2 Lamellar Ichthyosis - Market Size by Therapies
    15.4.2.1 Market Size by Therapies (2018-2023)
    15.4.2.2 Market Forecast by Therapies (2024-2034)
  15.4.3 Lamellar Ichthyosis - Access and Reimbursement Overview
15.5 Market Scenario - France
  15.5.1 Lamellar Ichthyosis - Market Size
    15.5.1.1 Market Size (2018-2023)
    15.5.1.2 Market Forecast (2024-2034)
  15.5.2 Lamellar Ichthyosis - Market Size by Therapies
    15.5.2.1 Market Size by Therapies (2018-2023)
    15.5.2.2 Market Forecast by Therapies (2024-2034)
  15.5.3 Lamellar Ichthyosis - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
  15.6.1 Lamellar Ichthyosis - Market Size
    15.6.1.1 Market Size (2018-2023)
    15.6.1.2 Market Forecast (2024-2034)
  15.6.2 Lamellar Ichthyosis - Market Size by Therapies
    15.6.2.1 Market Size by Therapies (2018-2023)
    15.6.2.2 Market Forecast by Therapies (2024-2034)
  15.6.3 Lamellar Ichthyosis - Access and Reimbursement Overview
15.7 Market Scenario - Italy
  15.7.1 Lamellar Ichthyosis - Market Size
    15.7.1.1 Market Size (2018-2023)
    15.7.1.2 Market Forecast (2024-2034)
  15.7.2 Lamellar Ichthyosis - Market Size by Therapies
    15.7.2.1 Market Size by Therapies (2018-2023)
    15.7.2.2 Market Forecast by Therapies (2024-2034)
  15.7.3 Lamellar Ichthyosis - Access and Reimbursement Overview
15.8 Market Scenario - Spain
  15.8.1 Lamellar Ichthyosis - Market Size
    15.8.1.1 Market Size (2018-2023)
    15.8.1.2 Market Forecast (2024-2034)
  15.8.2 Lamellar Ichthyosis - Market Size by Therapies
    15.8.2.1 Market Size by Therapies (2018-2023)
    15.8.2.2 Market Forecast by Therapies (2024-2034)
  15.8.3 Lamellar Ichthyosis - Access and Reimbursement Overview
15.9 Market Scenario - Japan
  15.9.1 Lamellar Ichthyosis - Market Size
    15.9.1.1 Market Size (2018-2023)
    15.9.1.2 Market Forecast (2024-2034)
  15.9.2 Lamellar Ichthyosis - Market Size by Therapies
    15.9.2.1 Market Size by Therapies (2018-2023)
    15.9.2.2 Market Forecast by Therapies (2024-2034)
  15.9.3 Lamellar Ichthyosis - Access and Reimbursement Overview

16 LAMELLAR ICHTHYOSIS - RECENT EVENTS AND INPUTS FROM KEY OPINION LEADERS

17 LAMELLAR ICHTHYOSIS MARKET - SWOT ANALYSIS

17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats

18 LAMELLAR ICHTHYOSIS MARKET – STRATEGIC RECOMMENDATIONS

19 APPENDIX


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