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Hypersomnia Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

May 2024 | 129 pages | ID: H369B153F193EN
IMARC Group

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The 7 major hypersomnia markets are expected to exhibit a CAGR of 6.68% during 2024-2034.

The hypersomnia market has been comprehensively analyzed in IMARC's new report titled "Hypersomnia Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Hypersomnia refers to a neurological disorder characterized by excessive daytime sleepiness and prolonged periods of sleep at night. Individuals suffering from this ailment often find it challenging to stay awake during the day, despite getting adequate sleep at night. The disease can significantly impact daily functioning, leading to difficulties in maintaining concentration, memory problems, and impaired performance at work or school. Some common symptoms of this ailment include persistent drowsiness, long naps that provide little relief, trouble waking up, confusion, reduced alertness, irritability, slow thinking and movements, mood swings, emotional instability, heightened anxiety, restlessness, sleep drunkenness, etc. The diagnosis of hypersomnia typically consists of a combination of the patient's medical history, clinical features, and physical examination. The healthcare provider may also perform actigraphy, which involves wearing a small, non-invasive device on the wrist that records movement and activity levels over an extended period to evaluate sleep-wake patterns and detect disruptions in the circadian rhythm. In some cases, blood workups may be performed to check for underlying medical conditions, such as thyroid disorders or metabolic issues, that could be contributing to hypersomnia.

The increasing cases of abnormalities in the neurotransmitters, including norepinephrine and gamma-aminobutyric acid (GABA), which affect the excitability levels in the brain, are primarily driving the hypersomnia market. Besides this, the rising incidences of certain neurological conditions, like depression, multiple sclerosis, head trauma, etc., that can disrupt sleep patterns and lead to excessive sleepiness are creating a positive outlook for the market. Moreover, the widespread adoption of cognitive behavioral therapy to identify negative thoughts and substitute them with more adaptive and positive thinking is further bolstering the market growth. Apart from this, the inflating application of non-stimulant medications, such as sodium oxybate and armodafinil, since they can promote restorative sleep without altering the natural sleep-wake cycle, thereby providing a sustained and steady improvement in wakefulness throughout the day, is acting as another significant growth-inducing factor. Additionally, the emerging popularity of continuous positive airway pressure therapy, which helps to maintain an open and unobstructed airway during sleep, ensuring persistent airflow to the lungs, is expected to drive the hypersomnia market during the forecast period.

IMARC Group's new report provides an exhaustive analysis of the hypersomnia market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for hypersomnia and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the hypersomnia market in any manner.

Time Period of the Study

Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034

Countries Covered

United States
Germany
France
United Kingdom
Italy
Spain
Japan

Analysis Covered Across Each Country

Historical, current, and future epidemiology scenario
Historical, current, and future performance of the hypersomnia market
Historical, current, and future performance of various therapeutic categories in the market
Sales of various drugs across the hypersomnia market
Reimbursement scenario in the market
In-market and pipeline drugs
Competitive Landscape:
This report also provides a detailed analysis of the current hypersomnia marketed drugs and late-stage pipeline drugs.

In-Market Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.

Key Questions Answered in this Report:
Market Insights

How has the hypersomnia market performed so far and how will it perform in the coming years?
What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
What was the country-wise size of the hypersomnia market across the seven major markets in 2023 and what will it look like in 2034?
What is the growth rate of the hypersomnia market across the seven major markets and what will be the expected growth over the next ten years?
What are the key unmet needs in the market?

Epidemiology Insights

What is the number of prevalent cases (2018-2034) of hypersomnia across the seven major markets?
What is the number of prevalent cases (2018-2034) of hypersomnia by age across the seven major markets?
What is the number of prevalent cases (2018-2034) of hypersomnia by gender across the seven major markets?
How many patients are diagnosed (2018-2034) with hypersomnia across the seven major markets?
What is the size of the hypersomnia patient pool (2018-2023) across the seven major markets?
What would be the forecasted patient pool (2024-2034) across the seven major markets?
What are the key factors driving the epidemiological trend of hypersomnia?
What will be the growth rate of patients across the seven major markets?

Hypersomnia: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

What are the current marketed drugs and what are their market performance?
What are the key pipeline drugs and how are they expected to perform in the coming years?
How safe are the current marketed drugs and what are their efficacies?
How safe are the late-stage pipeline drugs and what are their efficacies?
What are the current treatment guidelines for hypersomnia drugs across the seven major markets?
Who are the key companies in the market and what are their market shares?
What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the hypersomnia market?
What are the key regulatory events related to the hypersomnia market?
What is the structure of clinical trial landscape by status related to the hypersomnia market?
What is the structure of clinical trial landscape by phase related to the hypersomnia market?
What is the structure of clinical trial landscape by route of administration related to the hypersomnia market?
1 PREFACE

2 SCOPE AND METHODOLOGY

2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
  2.3.1 Primary Sources
  2.3.2 Secondary Sources
2.4 Market Estimation
  2.4.1 Bottom-Up Approach
  2.4.2 Top-Down Approach
2.5 Forecasting Methodology

3 EXECUTIVE SUMMARY

4 HYPERSOMNIA - INTRODUCTION

4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence

5 HYPERSOMNIA - DISEASE OVERVIEW

5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment

6 PATIENT JOURNEY

7 HYPERSOMNIA - EPIDEMIOLOGY AND PATIENT POPULATION

7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
  7.2.1 Epidemiology Scenario (2018-2023)
  7.2.2 Epidemiology Forecast (2024-2034)
  7.2.3 Epidemiology by Age (2018-2034)
  7.2.4 Epidemiology by Gender (2018-2034)
  7.2.5 Diagnosed Cases (2018-2034)
  7.2.6 Patient Pool/Treated Cases (2018-2034)
7.3 Epidemiology Scenario - United States
  7.3.1 Epidemiology Scenario (2018-2023)
  7.3.2 Epidemiology Forecast (2024-2034)
  7.3.3 Epidemiology by Age (2018-2034)
  7.3.4 Epidemiology by Gender (2018-2034)
  7.3.5 Diagnosed Cases (2018-2034)
  7.3.6 Patient Pool/Treated Cases (2018-2034)
7.4 Epidemiology Scenario - Germany
  7.4.1 Epidemiology Scenario (2018-2023)
  7.4.2 Epidemiology Forecast (2024-2034)
  7.4.3 Epidemiology by Age (2018-2034)
  7.4.4 Epidemiology by Gender (2018-2034)
  7.4.5 Diagnosed Cases (2018-2034)
  7.4.6 Patient Pool/Treated Cases (2018-2034)
7.5 Epidemiology Scenario - France
  7.5.1 Epidemiology Scenario (2018-2023)
  7.5.2 Epidemiology Forecast (2024-2034)
  7.5.3 Epidemiology by Age (2018-2034)
  7.5.4 Epidemiology by Gender (2018-2034)
  7.5.5 Diagnosed Cases (2018-2034)
  7.5.6 Patient Pool/Treated Cases (2018-2034)
7.6 Epidemiology Scenario - United Kingdom
  7.6.1 Epidemiology Scenario (2018-2023)
  7.6.2 Epidemiology Forecast (2024-2034)
  7.6.3 Epidemiology by Age (2018-2034)
  7.6.4 Epidemiology by Gender (2018-2034)
  7.6.5 Diagnosed Cases (2018-2034)
  7.6.6 Patient Pool/Treated Cases (2018-2034)
7.7 Epidemiology Scenario - Italy
  7.7.1 Epidemiology Scenario (2018-2023)
  7.7.2 Epidemiology Forecast (2024-2034)
  7.7.3 Epidemiology by Age (2018-2034)
  7.7.4 Epidemiology by Gender (2018-2034)
  7.7.5 Diagnosed Cases (2018-2034)
  7.7.6 Patient Pool/Treated Cases (2018-2034)
7.8 Epidemiology Scenario - Spain
  7.8.1 Epidemiology Scenario (2018-2023)
  7.8.2 Epidemiology Forecast (2024-2034)
  7.8.3 Epidemiology by Age (2018-2034)
  7.8.4 Epidemiology by Gender (2018-2034)
  7.8.5 Diagnosed Cases (2018-2034)
  7.8.6 Patient Pool/Treated Cases (2018-2034)
7.9 Epidemiology Scenario - Japan
  7.9.1 Epidemiology Scenario (2018-2023)
  7.9.2 Epidemiology Forecast (2024-2034)
  7.9.3 Epidemiology by Age (2018-2034)
  7.9.4 Epidemiology by Gender (2018-2034)
  7.9.5 Diagnosed Cases (2018-2034)
  7.9.6 Patient Pool/Treated Cases (2018-2034)

8 HYPERSOMNIA - TREATMENT ALGORITHM, GUIDELINES, AND MEDICAL PRACTICES

8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm

9 HYPERSOMNIA - UNMET NEEDS

10 HYPERSOMNIA - KEY ENDPOINTS OF TREATMENT

11 HYPERSOMNIA - MARKETED PRODUCTS

11.1 List of Hypersomnia Marketed Drugs Across the Top 7 Markets
  11.1.1 Xywav (Calcium/magnesium/potassium/sodium oxybates) - Jazz Pharmaceuticals
    11.1.1.1 Drug Overview
    11.1.1.2 Mechanism of Action
    11.1.1.3 Regulatory Status
    11.1.1.4 Clinical Trial Results
    11.1.1.5 Sales Across Major Markets
  11.1.2 Wakix (Pitolisant) - Bioprojet
    11.1.2.1 Drug Overview
    11.1.2.2 Mechanism of Action
    11.1.2.3 Regulatory Status
    11.1.2.4 Clinical Trial Results
    11.1.2.5 Sales Across Major Markets
  11.1.3 Sunosi (Solriamfetol) - Jazz Pharmaceuticals/SK Biopharmaceuticals
    11.1.3.1 Drug Overview
    11.1.3.2 Mechanism of Action
    11.1.3.3 Regulatory Status
    11.1.3.4 Clinical Trial Results
    11.1.3.5 Sales Across Major Markets
  11.1.4 cccccccc(Armodafini) - Teva Pharmaceutical
    11.1.4.1 Drug Overview
    11.1.4.2 Mechanism of Action
    11.1.4.3 Regulatory Status
    11.1.4.4 Clinical Trial Results
    11.1.4.5 Sales Across Major Markets
Kindly note that the above only represents a partial list of marketed drugs, and the complete list has been provided in the report.

12 HYPERSOMNIA - PIPELINE DRUGS

12.1 List of Hypersomnia Pipeline Drugs Across the Top 7 Markets
  12.1.1 Serdexmethylphenidate - Zevra Therapeutics
    12.1.1.1 Drug Overview
    12.1.1.2 Mechanism of Action
    12.1.1.3 Clinical Trial Results
    12.1.1.4 Safety and Efficacy
    12.1.1.5 Regulatory Status
  12.1.2 BTD 001 - Balance Therapeutics
    12.1.2.1 Drug Overview
    12.1.2.2 Mechanism of Action
    12.1.2.3 Clinical Trial Results
    12.1.2.4 Safety and Efficacy
    12.1.2.5 Regulatory Status
Kindly note that the above only represents a partial list of pipeline drugs, and the complete list has been provided in the report.

13. HYPERSOMNIA - ATTRIBUTE ANALYSIS OF KEY MARKETED AND PIPELINE DRUGS

14. HYPERSOMNIA – CLINICAL TRIAL LANDSCAPE

14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events

15 HYPERSOMNIA - MARKET SCENARIO

15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
  15.2.1 Hypersomnia - Market Size
    15.2.1.1 Market Size (2018-2023)
    15.2.1.2 Market Forecast (2024-2034)
  15.2.2 Hypersomnia - Market Size by Therapies
    15.2.2.1 Market Size by Therapies (2018-2023)
    15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
  15.3.1 Hypersomnia - Market Size
    15.3.1.1 Market Size (2018-2023)
    15.3.1.2 Market Forecast (2024-2034)
  15.3.2 Hypersomnia - Market Size by Therapies
    15.3.2.1 Market Size by Therapies (2018-2023)
    15.3.2.2 Market Forecast by Therapies (2024-2034)
  15.3.3 Hypersomnia - Access and Reimbursement Overview
15.4 Market Scenario - Germany
  15.4.1 Hypersomnia - Market Size
    15.4.1.1 Market Size (2018-2023)
    15.4.1.2 Market Forecast (2024-2034
  15.4.2 Hypersomnia - Market Size by Therapies
    15.4.2.1 Market Size by Therapies (2018-2023)
    15.4.2.2 Market Forecast by Therapies (2024-2034)
  15.4.3 Hypersomnia - Access and Reimbursement Overview
15.5 Market Scenario - France
  15.5.1 Hypersomnia - Market Size
    15.5.1.1 Market Size (2018-2023)
    15.5.1.2 Market Forecast (2024-2034)
  15.5.2 Hypersomnia - Market Size by Therapies
    15.5.2.1 Market Size by Therapies (2018-2023)
    15.5.2.2 Market Forecast by Therapies (2024-2034)
  15.5.3 Hypersomnia - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
  15.6.1 Hypersomnia - Market Size
    15.6.1.1 Market Size (2018-2023)
    15.6.1.2 Market Forecast (2024-2034)
  15.6.2 Hypersomnia - Market Size by Therapies
    15.6.2.1 Market Size by Therapies (2018-2023)
    15.6.2.2 Market Forecast by Therapies (2024-2034)
  15.6.3 Hypersomnia - Access and Reimbursement Overview
15.7 Market Scenario - Italy
  15.7.1 Hypersomnia - Market Size
    15.7.1.1 Market Size (2018-2023)
    15.7.1.2 Market Forecast (2024-2034)
  15.7.2 Hypersomnia - Market Size by Therapies
    15.7.2.1 Market Size by Therapies (2018-2023)
    15.7.2.2 Market Forecast by Therapies (2024-2034)
  15.7.3 Hypersomnia - Access and Reimbursement Overview
15.8 Market Scenario - Spain
  15.8.1 Hypersomnia - Market Size
    15.8.1.1 Market Size (2018-2023)
    15.8.1.2 Market Forecast (2024-2034)
  15.8.2 Hypersomnia - Market Size by Therapies
    15.8.2.1 Market Size by Therapies (2018-2023)
    15.8.2.2 Market Forecast by Therapies (2024-2034)
  15.8.3 Hypersomnia - Access and Reimbursement Overview
15.9 Market Scenario - Japan
  15.9.1 Hypersomnia - Market Size
    15.9.1.1 Market Size (2018-2023)
    15.9.1.2 Market Forecast (2024-2034)
  15.9.2 Hypersomnia - Market Size by Therapies
    15.9.2.1 Market Size by Therapies (2018-2023)
    15.9.2.2 Market Forecast by Therapies (2024-2034)
  15.9.3 Hypersomnia - Access and Reimbursement Overview

16 HYPERSOMNIA - RECENT EVENTS AND INPUTS FROM KEY OPINION LEADERS

17 HYPERSOMNIA MARKET - SWOT ANALYSIS

17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats

18 HYPERSOMNIA MARKET – STRATEGIC RECOMMENDATIONS

19 APPENDIX


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