Hyperoxaluria - Pipeline Insight, 2021
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DelveInsight’s, “Hyperoxaluria – Pipeline Insight, 2021,” report provides comprehensive insights about 10+ companies and 10+ pipeline drugs in Hyperoxaluria pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Geography Covered
HYPEROXALURIA: Overview
Hyperoxaluria is a condition that occurs when there is too much oxalate in the urine. Oxalate is a natural chemical in body and also contained in some foods, is normally eliminated from the body through the kidneys in the urine. Symptoms of hyperoxaluria can develop anytime from infancy to later adulthood (over 70 years of age). The most common initial symptom is usually kidney stones. Urine tests, Blood tests and scans may contribute to the diagnosis of Hyperoxaluria. The goal of treatment is to lower the level of oxalate in the body and prevent calcium oxalate crystals from forming in the kidneys and other body tissues.
'HYPEROXALURIA - Pipeline Insight, 2021' report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the HYPEROXALURIA pipeline landscape is provided which includes the disease overview and HYPEROXALURIA treatment guidelines. The assessment part of the report embraces, in depth HYPEROXALURIA commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, HYPEROXALURIA collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
Report Highlights
The companies and academics are working to assess challenges and seek opportunities that could influence HYPEROXALURIA R&D. The therapies under development are focused on novel approaches to treat/improve HYPEROXALURIA.
HYPEROXALURIA Emerging Drugs Chapters
This segment of the HYPEROXALURIA report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
HYPEROXALURIA Emerging Drugs
Oxabact: OxaThera
Oxalobacter formigenes is an anaerobe, non-pathogenic bacterium which exclusively uses oxalate as the energy source. OxThera has taken this bacterial strain isolated from the human gut and developed a live biotherapeutic product candidate. Oxabact is being studied in phase III stage of development for the treatment of primary hyperoxaluria.
Reloxiliase: Allen Pharmaceuticals
Reloxaliase (formerly ALLN-177), is a first-in-class, non-absorbed, orally-administered enzyme for the treatment of hyperoxaluria. Reloxaliase, a crystalline formulation of the enzyme oxalate decarboxylase, has been designed to specifically degrade oxalate within the GI tract, thus limiting systemic absorption of oxalate into the bloodstream. Reloxiliase is being evaluated for the treatment of Hyperoxaluria in phase III stage of development.
Stiripentol: Biocodex
Stiripentol is an orally active compound originated by Biocodex that inhibits several P450 cytochromes. Stiripentol developed by Biocodex is being studied in phase II stage of development for the treatment of primary Hyperoxluria.
Further product details are provided in the report……..
HYPEROXALURIA: Therapeutic Assessment
This segment of the report provides insights about the different HYPEROXALURIA drugs segregated based on following parameters that define the scope of the report, such as:
Major Players in HYPEROXALURIA
There are approx. 10+ key companies which are developing the therapies for HYPEROXALURIA. The companies which have their HYPEROXALURIA drug candidates in the most advanced stage, i.e. phase III include, OxaThera.
Phases
DelveInsight’s report covers around 10+ products under different phases of clinical development like
HYPEROXALURIA pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
Products have been categorized under various Molecule types such as
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.
HYPEROXALURIA: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses HYPEROXALURIA therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging HYPEROXALURIA drugs.
HYPEROXALURIA Report Insights
Current Treatment Scenario and Emerging Therapies:
DelveInsight’s, “Hyperoxaluria – Pipeline Insight, 2021,” report provides comprehensive insights about 10+ companies and 10+ pipeline drugs in Hyperoxaluria pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Geography Covered
- Global coverage
HYPEROXALURIA: Overview
Hyperoxaluria is a condition that occurs when there is too much oxalate in the urine. Oxalate is a natural chemical in body and also contained in some foods, is normally eliminated from the body through the kidneys in the urine. Symptoms of hyperoxaluria can develop anytime from infancy to later adulthood (over 70 years of age). The most common initial symptom is usually kidney stones. Urine tests, Blood tests and scans may contribute to the diagnosis of Hyperoxaluria. The goal of treatment is to lower the level of oxalate in the body and prevent calcium oxalate crystals from forming in the kidneys and other body tissues.
'HYPEROXALURIA - Pipeline Insight, 2021' report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the HYPEROXALURIA pipeline landscape is provided which includes the disease overview and HYPEROXALURIA treatment guidelines. The assessment part of the report embraces, in depth HYPEROXALURIA commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, HYPEROXALURIA collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
Report Highlights
The companies and academics are working to assess challenges and seek opportunities that could influence HYPEROXALURIA R&D. The therapies under development are focused on novel approaches to treat/improve HYPEROXALURIA.
HYPEROXALURIA Emerging Drugs Chapters
This segment of the HYPEROXALURIA report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
HYPEROXALURIA Emerging Drugs
Oxabact: OxaThera
Oxalobacter formigenes is an anaerobe, non-pathogenic bacterium which exclusively uses oxalate as the energy source. OxThera has taken this bacterial strain isolated from the human gut and developed a live biotherapeutic product candidate. Oxabact is being studied in phase III stage of development for the treatment of primary hyperoxaluria.
Reloxiliase: Allen Pharmaceuticals
Reloxaliase (formerly ALLN-177), is a first-in-class, non-absorbed, orally-administered enzyme for the treatment of hyperoxaluria. Reloxaliase, a crystalline formulation of the enzyme oxalate decarboxylase, has been designed to specifically degrade oxalate within the GI tract, thus limiting systemic absorption of oxalate into the bloodstream. Reloxiliase is being evaluated for the treatment of Hyperoxaluria in phase III stage of development.
Stiripentol: Biocodex
Stiripentol is an orally active compound originated by Biocodex that inhibits several P450 cytochromes. Stiripentol developed by Biocodex is being studied in phase II stage of development for the treatment of primary Hyperoxluria.
Further product details are provided in the report……..
HYPEROXALURIA: Therapeutic Assessment
This segment of the report provides insights about the different HYPEROXALURIA drugs segregated based on following parameters that define the scope of the report, such as:
Major Players in HYPEROXALURIA
There are approx. 10+ key companies which are developing the therapies for HYPEROXALURIA. The companies which have their HYPEROXALURIA drug candidates in the most advanced stage, i.e. phase III include, OxaThera.
Phases
DelveInsight’s report covers around 10+ products under different phases of clinical development like
- Late stage products (Phase III)
- Mid-stage products (Phase II)
- Early-stage product (Phase I) along with the details of
- Pre-clinical and Discovery stage candidates
- Discontinued & Inactive candidates
HYPEROXALURIA pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
- Oral
- Subcutaneous
- Intravenous
- Intramuscular
Products have been categorized under various Molecule types such as
- Bispecific Antibody
- Peptides
- Small molecule
- Gene therapy
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.
HYPEROXALURIA: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses HYPEROXALURIA therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging HYPEROXALURIA drugs.
HYPEROXALURIA Report Insights
- HYPEROXALURIA Pipeline Analysis
- Therapeutic Assessment
- Unmet Needs
- Impact of Drugs
- Pipeline Product Profiles
- Therapeutic Assessment
- Pipeline Assessment
- Inactive drugs assessment
- Unmet Needs
Current Treatment Scenario and Emerging Therapies:
- How many companies are developing HYPEROXALURIA drugs?
- How many Hyperoxaluria drugs are developed by each company?
- How many emerging drugs are in mid-stage, and late-stage of development for the treatment of HYPEROXALURIA?
- What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the HYPEROXALURIA therapeutics?
- What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
- What are the clinical studies going on for HYPEROXALURIA and their status?
- What are the key designations that have been granted to the emerging drugs?
Introduction
Executive Summary
HYPEROXALURIA: Overview
Causes
Mechanism of Action
Signs and Symptoms
Diagnosis
Disease Management
Pipeline Therapeutics
Comparative Analysis
Therapeutic Assessment
Assessment by Product Type
Assessment by Stage and Product Type
Assessment by Route of Administration
Assessment by Stage and Route of Administration
Assessment by Molecule Type
Assessment by Stage and Molecule Type
HYPEROXALURIA – DelveInsight’s Analytical Perspective
In-depth Commercial Assessment
HYPEROXALURIA companies’ collaborations, Licensing, Acquisition -Deal Value Trends
HYPEROXALURIA Collaboration Deals
Company-Company Collaborations (Licensing / Partnering) Analysis
Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Phase III)
Comparative Analysis
Oxabact: OxaThera
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
Comparative Analysis
Stiripentol: Biocodex
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Early Stage Products (Phase I/II)
Comparative Analysis
SYNB8802: Synlogic
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Preclinical Stage Products
Comparative Analysis
CHK-339: Chinook therapeutics
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
Comparative Analysis
HYPEROXALURIA Key Companies
HYPEROXALURIA Key Products
HYPEROXALURIA- Unmet Needs
HYPEROXALURIA- Market Drivers and Barriers
HYPEROXALURIA- Future Perspectives and Conclusion
HYPEROXALURIA Analyst Views
HYPEROXALURIA Key Companies
Appendix
Executive Summary
HYPEROXALURIA: Overview
Causes
Mechanism of Action
Signs and Symptoms
Diagnosis
Disease Management
Pipeline Therapeutics
Comparative Analysis
Therapeutic Assessment
Assessment by Product Type
Assessment by Stage and Product Type
Assessment by Route of Administration
Assessment by Stage and Route of Administration
Assessment by Molecule Type
Assessment by Stage and Molecule Type
HYPEROXALURIA – DelveInsight’s Analytical Perspective
In-depth Commercial Assessment
HYPEROXALURIA companies’ collaborations, Licensing, Acquisition -Deal Value Trends
HYPEROXALURIA Collaboration Deals
Company-Company Collaborations (Licensing / Partnering) Analysis
Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Phase III)
Comparative Analysis
Oxabact: OxaThera
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
Comparative Analysis
Stiripentol: Biocodex
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Early Stage Products (Phase I/II)
Comparative Analysis
SYNB8802: Synlogic
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Preclinical Stage Products
Comparative Analysis
CHK-339: Chinook therapeutics
Product Description
Research and Development
Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
Comparative Analysis
HYPEROXALURIA Key Companies
HYPEROXALURIA Key Products
HYPEROXALURIA- Unmet Needs
HYPEROXALURIA- Market Drivers and Barriers
HYPEROXALURIA- Future Perspectives and Conclusion
HYPEROXALURIA Analyst Views
HYPEROXALURIA Key Companies
Appendix
LIST OF TABLES
Table 1 Total Products for HYPEROXALURIA
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products
Table 1 Total Products for HYPEROXALURIA
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products
LIST OF FIGURES
Figure 1 Total Products for HYPEROXALURIA
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products
Figure 1 Total Products for HYPEROXALURIA
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products
