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Humanized Mice Model Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Type (Humanized Mice Models, Humanized Rat Models), By Application (Oncology, Immunology & Infectious Diseases, Toxicology, Others), By End User (Pharmaceutical & Biotechnology Companies, Contract Research Organizations, Academic & Research Institutions), By Region and Competition, 2019-2029F

July 2024 | 180 pages | ID: H088E7D834C0EN
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Global Humanized Mice Model Market was valued at USD 1.15 Billion in 2023 and is anticipated t%li%project robust growth in the forecast period with a CAGR of 9.80% through 2029. Humanized mice models are mice that have undergone xenotransplantation with human cells or have been genetically engineered t%li%express human genes. These mice are extensively utilized in elucidating and comprehending human physiology and the etiology of human-specific infections. Humanized mice play a crucial role in biomedical research for the development of human therapeutics, owing t%li%their numerous advantages such as small size, short reproductive cycle, ease of handling, and increased genomic similarity t%li%humans. These models serve as critical tools in preclinical research studies, as they can mimic several human-specific diseases and enable the study of immunotherapy approaches' efficacy and safety. Notably, humanized mice models have significantly contributed t%li%the design and development of vaccines and antibody-based therapies for COVID-19. Since the outbreak of coronavirus infection, these models are expected t%li%provide a deeper and more comprehensive understanding of the infection, the effectiveness of antiviral therapeutics, and support the development of efficient drugs and therapies for the treatment of this disease. It is anticipated that this trend will continue, contributing t%li%the revenue growth of the market.

Key Market Drivers

Increasing Need for Personalized Medicine

Precision or personalized medicine is a groundbreaking and transformative approach that revolutionizes the healthcare industry. It focuses on creating tailored medications and therapeutic strategies that address the individual complexity and genetic variations of patients in a highly precise manner. By utilizing advanced techniques, such as next-generation sequencing and high-throughput screening, researchers can gain a comprehensive understanding of the genetic makeup of patients and identify specific molecular targets for treatment. One significant aspect of precision medicine is the development and utilization of mice models, particularly immunodeficient mice models that can express human-specific pathologies. These models enable researchers t%li%mimic human diseases and study their mechanisms in a controlled environment. By investigating the underlying molecular mechanisms of diseases, researchers can identify potential targets for drug development and gene therapies.

Precision medicine goes beyond a one-size-fits-all approach by tailoring treatment options t%li%suit each patient's unique needs. By analyzing an individual's genetic profile, lifestyle factors, and environmental influences, healthcare providers can determine the most suitable treatment options for optimizing patient outcomes. This personalized approach holds great promise in transforming the way we diagnose, treat, and manage diseases, ultimately improving the quality of life for patients worldwide. The potential of precision medicine t%li%revolutionize healthcare is expected t%li%drive significant revenue growth in the market over the forecast period. With ongoing advancements in technology and research, precision medicine will continue t%li%provide personalized solutions that enhance patient care and lead t%li%better health outcomes. By embracing this innovative approach, we can unlock new possibilities in the field of medicine and pave the way for a healthier future.

Advancement In Gene Editing Tools

The advent of advanced gene editing tools, such as CRISPR/Cas9 technology, have revolutionized the field of biomedical research. With these powerful tools at our disposal, scientists have been able t%li%accelerate the development of mutant and genetically engineered mice, enabling them t%li%study the intricate characteristics of various diseases in more depth than ever before. This breakthrough technology is not only expected t%li%significantly contribute t%li%the advancement of scientific knowledge but als%li%holds the potential t%li%drive substantial revenue growth in the market moving forward. By providing researchers with precise and efficient genome editing capabilities, CRISPR/Cas9 has opened up new possibilities for targeted gene therapies and personalized medicine. Its potential impact ranges from treating genetic diseases t%li%improving crop production and environmental conservation.

The ability t%li%precisely edit DNA sequences has unlocked a wealth of opportunities for biomedical research and biotechnology, with implications that extend far beyond the laboratory. As the technology continues t%li%evolve and be refined, we can anticipate even more exciting breakthroughs in the field of gene editing. The ongoing advancements in CRISPR/Cas9 and related tools promise t%li%revolutionize not only how we understand and treat diseases but als%li%how we shape the world around us. The future of biomedical research and its potential for transformative impact has never been more promising.

Increasing Innovation in Mice Models

The drive t%li%enhance biomedical research and drug development has ignited a rapid evolution in the realm of mice models, with a particular emphasis on humanized mice. These innovative models, genetically modified t%li%incorporate human genes, tissues, or immune systems, hold immense promise in mirroring human physiological responses and disease pathways more accurately than conventional animal models. As scientific understanding becomes increasingly intricate, the demand for sophisticated tools that can faithfully recapitulate human conditions surges. This is where humanized mice models come t%li%the fore. By offering a platform t%li%simulate human-specific diseases, evaluate novel therapies, and unravel complex immune interactions, these models stand as invaluable assets in modern medical research.

The prospect of advancing innovation in mice models translates t%li%a cascade of benefits, propelling the demand for humanized mice models. Researchers are presented with an unparalleled opportunity t%li%delve int%li%the intricacies of human biology, conduct safer and more efficient preclinical drug trials, and personalize treatment strategies. This heightened demand resonates across various fields, from oncology and immunology t%li%infectious diseases, as scientists recognize the potential t%li%bridge the gap between bench and bedside. Pharmaceutical and biotechnology industries keen on expediting drug discovery and development find in humanized mice models a potent catalyst for success.

Growing Pipeline of Pharmaceutical & Biopharmaceutical Companies

The growing pipeline of pharmaceutical and biopharmaceutical companies is poised t%li%usher in a significant surge in the demand for humanized mice models. This heightened demand can be attributed t%li%the increasingly complex landscape of drug development, where precision and predictive models are indispensable. Humanized mice models, genetically engineered t%li%incorporate human genes, immune systems, or tissues, offer a remarkable platform for assessing drug efficacy, safety, and toxicity with a level of accuracy that traditional animal models cannot match. The demand for humanized mice models is amplified by the imperative t%li%address a diverse range of therapeutic areas, from oncology and immunology t%li%infectious diseases and regenerative medicine. As these industries grow, s%li%does the necessity for reliable and versatile preclinical models that can bridge the translational gap between the laboratory and clinical trials.

The burgeoning pipeline of pharmaceutical and biopharmaceutical companies is driving a robust demand for humanized mice models. These models are the linchpin in modern drug development efforts, offering the precision and fidelity required t%li%navigate the intricacies of human biology and disease. As the pharmaceutical and biopharmaceutical sectors continue t%li%expand and evolve, humanized mice models are destined t%li%play an increasingly pivotal role in advancing drug discovery and ultimately improving patient outcomes.

Key Market Challenges

High costs Associated with Development of Humanized Mice Models

Humanized mice models, a cutting-edge approach in biomedical research, involve the grafting of human tissues, genes, and cells int%li%immunodeficient mice. While these models hold great promise in advancing our understanding of human diseases and developing novel therapies, their widespread adoption has been limited due t%li%the substantial expenses associated with their production and maintenance. This financial burden has hindered the global expansion of humanized mice models, placing a certain degree of constraint on market growth in the foreseeable future.

The utilization of animal models in experiments and preclinical studies is subject t%li%stringent regulatory frameworks. These regulations aim t%li%ensure ethical treatment and minimize animal suffering, but they als%li%pose challenges t%li%the broader implementation of humanized mice models. As a result, market growth in this field is expected t%li%face significant hurdles in the coming years. Despite these obstacles, ongoing advancements in technology and increasing efforts t%li%refine animal research practices offer glimpses of hope. With continued innovation and collaboration, the potential of humanized mice models can be fully realized, paving the way for groundbreaking discoveries and transformative medical interventions.

Regulations for the Ethical Use of Animals

The demand for humanized mice models is set t%li%experience a significant uptick due t%li%the increasingly stringent regulations governing the ethical use of animals in research. In response t%li%growing concerns about animal welfare and ethical considerations, regulatory authorities around the world have been implementing and reinforcing guidelines aimed at minimizing the use of traditional animal models. This shift towards more ethical research practices has led t%li%a heightened interest in humanized mice models as a viable alternative.

This growing emphasis on ethical research practices, combined with an increasing awareness of the limitations and ethical concerns associated with traditional animal models, is propelling the demand for humanized mice models. These models not only satisfy regulatory requirements but als%li%offer researchers a more accurate and human-relevant platform for preclinical testing and drug development. As a result, pharmaceutical companies, biotechnology firms, and academic institutions are increasingly turning t%li%humanized mice models as a responsible and ethical choice, ultimately contributing t%li%a more compassionate and responsible approach t%li%biomedical research.

Key Market Trends

Increasing Innovation in Mice Models

The increasing innovation in mice models is poised t%li%have a transformative impact on the future of biomedical research, significantly driving up the demand for these models. Mice have long served as a cornerstone of preclinical research due t%li%their genetic similarity t%li%humans and relatively short breeding cycles. However, recent advancements in genetic engineering, genome editing, and model development techniques are expanding the possibilities and applications of mice models in unprecedented ways. Innovations in mice models extend beyond genetic modifications. Advanced techniques like the generation of humanized mice, where human cells, tissues, or organs are incorporated, have opened new frontiers in the study of human-specific diseases, immune responses, and personalized medicine. The ability t%li%simulate intricate aspects of human biology within a living organism is revolutionizing drug testing and therapeutic development, attracting substantial interest from researchers across various fields.

The increasing innovation in mice models is driving an upsurge in demand, promising a future where these models will play an even more pivotal role in biomedical research and drug discovery. As scientific understanding deepens and technologies continue t%li%evolve, mice models are positioned t%li%remain at the forefront of cutting-edge research, ultimately contributing t%li%groundbreaking discoveries and improved healthcare outcomes for the future.

Progress In Genomics, Proteomics, And Metabolomics

The increasing innovation in mice models is poised t%li%have a transformative impact on the future of biomedical research, significantly driving up the demand for these models. Mice have long served as a cornerstone of preclinical research due t%li%their genetic similarity t%li%humans and relatively short breeding cycles. However, recent advancements in genetic engineering, genome editing, and model development techniques are expanding the possibilities and applications of mice models in unprecedented ways.

Innovations in mice models extend beyond genetic modifications. Advanced techniques like the generation of humanized mice, where human cells, tissues, or organs are incorporated, have opened new frontiers in the study of human-specific diseases, immune responses, and personalized medicine. The ability t%li%simulate intricate aspects of human biology within a living organism is revolutionizing drug testing and therapeutic development, attracting substantial interest from researchers across various fields.

Segmental Insights

Application Insights

Based on application, the global humanized mice model market has been segmented int%li%oncology, immunology & infectious diseases, toxicology, and others. Within the oncology segment, it is anticipated that there will be a substantial increase in revenue CAGR over the forecast period. This can be attributed t%li%the rising prevalence of cancer worldwide, along with the growing focus on cancer research and development activities. There is an increasing need t%li%address unmet clinical demands, which further drives the demand for humanized mice models in oncology research. Humanized mice models offer a more realistic and comprehensive approach t%li%studying tumour biology compared t%li%traditional methods such as cultured cancer cells. This enhanced realism not only facilitates a better understanding of tumour growth and progression but als%li%enables researchers t%li%evaluate the efficacy of various therapeutic interventions. As a result, the adoption of humanized mice models in oncology research is expected t%li%contribute significantly t%li%the growth of the market over the forecast period.

Regional Insights

North America is projected t%li%hold the largest market share in terms of revenue over the forecast period. This growth can be attributed t%li%the increasing research activities in the pharmaceutical and biotechnology sectors in the United States, the growing biopharmaceutical industry, the rising demand and production of monoclonal antibodies, and advancements in protein therapeutics. The region is expected t%li%witness revenue growth due t%li%the growing number of preclinical and clinical activities by Contract Research Organizations (CROs), rapid progress in stem cell research, and increased government support.

In the Asia Pacific region, a robust revenue Compound Annual Growth Rate (CAGR) is anticipated during the forecast period. This can be attributed t%li%the rapid growth of the biomedical sector, advancements in translational research, and the increasing demand for precision medicine in countries such as India, China, Japan, and other APAC countries. Notably, China is expected t%li%hold the largest revenue share in the Asia Pacific market due t%li%the increasing animal research, mandatory animal testing for pharmaceutical drugs and cosmetics, the growing biomedical sector, and the rapid rise in strategic alliances between research institutes in China and international institutes and companies. Factors such as the availability of a massive target patient pool, low cost of clinical trials, and lenient regulatory approvals are als%li%expected t%li%contribute t%li%the revenue growth of the market in the region.

Key Market Players
  • Allentown LLC
  • Charles River Laboratories International, Inc.
  • HBM Holdings
  • Horizon Discovery Group plc
  • Ingenious Targeting Laboratory Inc.
  • Janvier Labs
  • Trans Genic Inc.
  • PolyGene AG
  • Aragen Life Sciences Ltd.
  • The Andersons, Inc.
Report Scope:

In this report, the Global Humanized Mice Model Market has been segmented int%li%the following categories, in addition t%li%the industry trends which have als%li%been detailed below:
  • Humanized Mice Model Market, By Type:
  • Humanized Mouse Models
  • Humanized Rat Models
  • Humanized Mice Model Market, By Application:
  • Oncology
  • Immunology & Infectious Diseases
  • Toxicology
  • Others
  • Humanized Mice Model Market, By End User:
  • Pharmaceutical & Biotechnology Companies
  • Contract Research Organizations
  • Academic & Research Institutions
  • Humanized Mice Model Market, By Region:
  • North America
  • United States
  • Canada
  • Mexico
  • Europe
  • France
  • United Kingdom
  • Italy
  • Germany
  • Spain
  • Asia-Pacific
  • China
  • India
  • Japan
  • Australia
  • South Korea
  • South America
  • Brazil
  • Argentina
  • Colombia
  • Middle East & Africa
  • South Africa
  • Saudi Arabia
  • UAE
Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the Global Humanized Mice Model Market.

Available Customizations:

Global Humanized Mice Model market report with the given market data, Tech Sci Research offers customizations according t%li%a company's specific needs. The following customization options are available for the report:

Company Information
    • Detailed analysis and profiling of additional market players (up t%li%five).
1. PRODUCT OVERVIEW

1.1. Market Definition
1.2. Scope of the Market
  1.2.1. Markets Covered
  1.2.2. Years Considered for Study
  1.2.3. Key Market Segmentations

2. RESEARCH METHODOLOGY

2.1. Objective of the Study
2.2. Baseline Methodology
2.3. Key Industry Partners
2.4. Major Association and Secondary Sources
2.5. Forecasting Methodology
2.6. Data Triangulation & Validations
2.7. Assumptions and Limitations

3. EXECUTIVE SUMMARY

3.1. Overview of the Market
3.2. Overview of Key Market Segmentations
3.3. Overview of Key Market Players
3.4. Overview of Key Regions/Countries
3.5. Overview of Market Drivers, Challenges, Trends

4. VOICE OF CUSTOMER


5. GLOBAL HUMANIZED MICE MODEL MARKET OUTLOOK

5.1. Market Size & Forecast
  5.1.1. By Value
5.2. Market Share & Forecast
  5.2.1. By Type (Humanized Mouse Models, Humanized Rat Models)
  5.2.2. By Application (Oncology, Immunology & Infectious Diseases, Toxicology, Others)
  5.2.3. By End User (Pharmaceutical & Biotechnology Companies, Contract Research Organizations, Academic & Research Institutions)
  5.2.4. By Region
  5.2.5. By Company (2023)
5.3. Market Map

6. NORTH AMERICA HUMANIZED MICE MODEL MARKET OUTLOOK

6.1. Market Size & Forecast
  6.1.1. By Value
6.2. Market Share & Forecast
  6.2.1. By Type
  6.2.2. By Application
  6.2.3. By End User
  6.2.4. By Country
6.3. North America: Country Analysis
  6.3.1. United States Humanized Mice Model Market Outlook
    6.3.1.1. Market Size & Forecast
      6.3.1.1.1. By Value
    6.3.1.2. Market Share & Forecast
      6.3.1.2.1. By Type
      6.3.1.2.2. By Application
      6.3.1.2.3. By End User
  6.3.2. Canada Humanized Mice Model Market Outlook
    6.3.2.1. Market Size & Forecast
      6.3.2.1.1. By Value
    6.3.2.2. Market Share & Forecast
      6.3.2.2.1. By Type
      6.3.2.2.2. By Application
      6.3.2.2.3. By End User
  6.3.3. Mexico Humanized Mice Model Market Outlook
    6.3.3.1. Market Size & Forecast
      6.3.3.1.1. By Value
    6.3.3.2. Market Share & Forecast
      6.3.3.2.1. By Type
      6.3.3.2.2. By Application
      6.3.3.2.3. By End User

7. EUROPE HUMANIZED MICE MODEL MARKET OUTLOOK

7.1. Market Size & Forecast
  7.1.1. By Value
7.2. Market Share & Forecast
  7.2.1. By Type
  7.2.2. By Application
  7.2.3. By End User
  7.2.4. By Country
7.3. Europe: Country Analysis
  7.3.1. Germany Humanized Mice Model Market Outlook
    7.3.1.1. Market Size & Forecast
      7.3.1.1.1. By Value
    7.3.1.2. Market Share & Forecast
      7.3.1.2.1. By Type
      7.3.1.2.2. By Application
      7.3.1.2.3. By End User
  7.3.2. United Kingdom Humanized Mice Model Market Outlook
    7.3.2.1. Market Size & Forecast
      7.3.2.1.1. By Value
    7.3.2.2. Market Share & Forecast
      7.3.2.2.1. By Type
      7.3.2.2.2. By Application
      7.3.2.2.3. By End User
  7.3.3. Italy Humanized Mice Model Market Outlook
    7.3.3.1. Market Size & Forecast
      7.3.3.1.1. By Value
    7.3.3.2. Market Share & Forecasty
      7.3.3.2.1. By Type
      7.3.3.2.2. By Application
      7.3.3.2.3. By End User
  7.3.4. France Humanized Mice Model Market Outlook
    7.3.4.1. Market Size & Forecast
      7.3.4.1.1. By Value
    7.3.4.2. Market Share & Forecast
      7.3.4.2.1. By Type
      7.3.4.2.2. By Application
      7.3.4.2.3. By End User
  7.3.5. Spain Humanized Mice Model Market Outlook
    7.3.5.1. Market Size & Forecast
      7.3.5.1.1. By Value
    7.3.5.2. Market Share & Forecast
      7.3.5.2.1. By Type
      7.3.5.2.2. By Application
      7.3.5.2.3. By End User

8. ASIA-PACIFIC HUMANIZED MICE MODEL MARKET OUTLOOK

8.1. Market Size & Forecast
  8.1.1. By Value
8.2. Market Share & Forecast
  8.2.1. By Type
  8.2.2. By Application
  8.2.3. By End User
  8.2.4. By Country
8.3. Asia-Pacific: Country Analysis
  8.3.1. China Humanized Mice Model Market Outlook
    8.3.1.1. Market Size & Forecast
      8.3.1.1.1. By Value
    8.3.1.2. Market Share & Forecast
      8.3.1.2.1. By Type
      8.3.1.2.2. By Application
      8.3.1.2.3. By End User
  8.3.2. India Humanized Mice Model Market Outlook
    8.3.2.1. Market Size & Forecast
      8.3.2.1.1. By Value
    8.3.2.2. Market Share & Forecast
      8.3.2.2.1. By Type
      8.3.2.2.2. By Application
      8.3.2.2.3. By End User
  8.3.3. Japan Humanized Mice Model Market Outlook
    8.3.3.1. Market Size & Forecast
      8.3.3.1.1. By Value
    8.3.3.2. Market Share & Forecast
      8.3.3.2.1. By Type
      8.3.3.2.2. By Application
      8.3.3.2.3. By End User
  8.3.4. South Korea Humanized Mice Model Market Outlook
    8.3.4.1. Market Size & Forecast
      8.3.4.1.1. By Value
    8.3.4.2. Market Share & Forecast
      8.3.4.2.1. By Type
      8.3.4.2.2. By Application
      8.3.4.2.3. By End User
  8.3.5. Australia Humanized Mice Model Market Outlook
    8.3.5.1. Market Size & Forecast
      8.3.5.1.1. By Value
    8.3.5.2. Market Share & Forecast
      8.3.5.2.1. By Type
      8.3.5.2.2. By Application
      8.3.5.2.3. By End User

9. SOUTH AMERICA HUMANIZED MICE MODEL MARKET OUTLOOK

9.1. Market Size & Forecast
  9.1.1. By Value
9.2. Market Share & Forecast
  9.2.1. By Type
  9.2.2. By Application
  9.2.3. By End User
  9.2.4. By Country
9.3. South America: Country Analysis
  9.3.1. Brazil Humanized Mice Model Market Outlook
    9.3.1.1. Market Size & Forecast
      9.3.1.1.1. By Value
    9.3.1.2. Market Share & Forecast
      9.3.1.2.1. By Type
      9.3.1.2.2. By Application
      9.3.1.2.3. By End User
  9.3.2. Argentina Humanized Mice Model Market Outlook
    9.3.2.1. Market Size & Forecast
      9.3.2.1.1. By Value
    9.3.2.2. Market Share & Forecast
      9.3.2.2.1. By Type
      9.3.2.2.2. By Application
      9.3.2.2.3. By End User
  9.3.3. Colombia Humanized Mice Model Market Outlook
    9.3.3.1. Market Size & Forecast
      9.3.3.1.1. By Value
    9.3.3.2. Market Share & Forecast
      9.3.3.2.1. By Type
      9.3.3.2.2. By Application
      9.3.3.2.3. By End User

10. MIDDLE EAST AND AFRICA HUMANIZED MICE MODEL MARKET OUTLOOK

10.1. Market Size & Forecast
  10.1.1. By Value
10.2. Market Share & Forecast
  10.2.1. By Type
  10.2.2. By Application
  10.2.3. By End User
  10.2.4. By Country
10.3. MEA: Country Analysis
  10.3.1. South Africa Humanized Mice Model Market Outlook
    10.3.1.1. Market Size & Forecast
      10.3.1.1.1. By Value
    10.3.1.2. Market Share & Forecast
      10.3.1.2.1. By Type
      10.3.1.2.2. By Application
      10.3.1.2.3. By End User
  10.3.2. Saudi Arabia Humanized Mice Model Market Outlook
    10.3.2.1. Market Size & Forecast
      10.3.2.1.1. By Value
    10.3.2.2. Market Share & Forecast
      10.3.2.2.1. By Type
      10.3.2.2.2. By Application
      10.3.2.2.3. By End User
  10.3.3. UAE Humanized Mice Model Market Outlook
    10.3.3.1. Market Size & Forecast
      10.3.3.1.1. By Value
    10.3.3.2. Market Share & Forecast
      10.3.3.2.1. By Type
      10.3.3.2.2. By Application
      10.3.3.2.3. By End User

11. MARKET DYNAMICS

11.1. Drivers
11.2. Challenges

12. MARKET TRENDS & DEVELOPMENTS

12.1. Merger & Acquisition (If Any)
12.2. Product Launches (If Any)
12.3. Recent Developments

13. PORTERS FIVE FORCES ANALYSIS

13.1. Competition in the Industry
13.2. Potential of New Entrants
13.3. Power of Suppliers
13.4. Power of Customers
13.5. Threat of Substitute Products

14. COMPETITIVE LANDSCAPE

14.1. Allentown LLC
  14.1.1. Business Overview
  14.1.2. Company Snapshot
  14.1.3. Products & Services
  14.1.4. Financials (As Reported)
  14.1.5. Recent Developments
  14.1.6. Key Personnel Details
  14.1.7. SWOT Analysis
14.2. Charles River Laboratories International, Inc.
14.3. HBM Holdings
14.4. Horizon Discovery Group plc
14.5. Ingenious Targeting Laboratory Inc.
14.6. Janvier Labs
14.7. Trans Genic Inc.
14.8. PolyGene AG
14.9. Aragen Life Sciences Ltd.
14.10. The Andersons, Inc.

15. STRATEGIC RECOMMENDATIONS


16. ABOUT US & DISCLAIMER


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