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Hepatic Cirrhosis Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

May 2024 | 137 pages | ID: H873CB279708EN
IMARC Group

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The hepatic cirrhosis market has been comprehensively analyzed in IMARC's new report titled "Hepatic Cirrhosis Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Hepatic cirrhosis is a chronic liver condition characterized by the irreversible scarring of liver tissue, resulting in impaired liver function. This scarring disrupts the normal structure of the liver, replacing healthy tissue with fibrous bands. Common causes include chronic alcohol abuse, viral hepatitis, and fatty liver disease. As the ailment progresses, symptoms may manifest, including fatigue, weakness, abdominal pain, and unintended weight loss. Additionally, individuals suffering from this illness may experience complications such as ascites (fluid buildup in the abdomen), jaundice, and easy bruising or bleeding due to decreased production of clotting factors. Diagnosing hepatic cirrhosis often involves a combination of medical history review, physical examination, and diagnostic tests such as liver function tests, imaging studies (like ultrasound or CT scans), and sometimes a liver biopsy to assess the extent of liver damage.

The escalating incidence of somatic mutations, which contribute to the progressive overgrowth of fibrous tissue in the liver, disrupting its normal function, is primarily driving the hepatic cirrhosis market. In addition to this, the inflating utilization of effective medications, such as antifibrotic agents, diuretics, and beta-blockers, aimed at managing the condition and averting further hepatic damage is creating a positive outlook for the market. Moreover, the widespread adoption of physical and occupational therapies is also bolstering the market growth. These therapeutic interventions not only bolster muscular strength but also enhance coordination and improve gross motor skills in individuals suffering from the ailment. Apart from this, the rising usage of advanced procedures, including transjugular intrahepatic portosystemic shunt (TIPS) and liver transplantation, which aim to alleviate symptoms, reduce complications, and enhance the overall quality of life is acting as another significant growth-inducing factor. Additionally, the emerging popularity of gene therapy that involves the introduction of functional genetic material to rectify or replace mutated genes responsible for the underlying condition is expected to drive the hepatic cirrhosis market during the forecast period.

IMARC Group's new report provides an exhaustive analysis of the hepatic cirrhosis market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for hepatic cirrhosis and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the hepatic cirrhosis market in any manner.

Time Period of the Study

Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034

Countries Covered

United States
Germany
France
United Kingdom
Italy
Spain
Japan

Analysis Covered Across Each Country

Historical, current, and future epidemiology scenario
Historical, current, and future performance of the hepatic cirrhosis market
Historical, current, and future performance of various therapeutic categories in the market
Sales of various drugs across the hepatic cirrhosis market
Reimbursement scenario in the market
In-market and pipeline drugs
Competitive Landscape:
This report also provides a detailed analysis of the current hepatic cirrhosis marketed drugs and late-stage pipeline drugs.

In-Market Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report

Key Questions Answered in this Report:
Market Insights

How has the hepatic cirrhosis market performed so far and how will it perform in the coming years?
What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
What was the country-wise size of the hepatic cirrhosis market across the seven major markets in 2023 and what will it look like in 2034?
What is the growth rate of the hepatic cirrhosis market across the seven major markets and what will be the expected growth over the next ten years?
What are the key unmet needs in the market?

Epidemiology Insights

What is the number of prevalent cases (2018-2034) of hepatic cirrhosis across the seven major markets?
What is the number of prevalent cases (2018-2034) of hepatic cirrhosis by age across the seven major markets?
What is the number of prevalent cases (2018-2034) of hepatic cirrhosis by gender across the seven major markets?
How many patients are diagnosed (2018-2034) with hepatic cirrhosis across the seven major markets?
What is the size of the hepatic cirrhosis patient pool (2018-2023) across the seven major markets?
What would be the forecasted patient pool (2024-2034) across the seven major markets?
What are the key factors driving the epidemiological trend of hepatic cirrhosis?
What will be the growth rate of patients across the seven major markets?

Hepatic Cirrhosis: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

What are the current marketed drugs and what are their market performance?
What are the key pipeline drugs and how are they expected to perform in the coming years?
How safe are the current marketed drugs and what are their efficacies?
How safe are the late-stage pipeline drugs and what are their efficacies?
What are the current treatment guidelines for hepatic cirrhosis drugs across the seven major markets?
Who are the key companies in the market and what are their market shares?
What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the hepatic cirrhosis market?
What are the key regulatory events related to the hepatic cirrhosis market?
What is the structure of clinical trial landscape by status related to the hepatic cirrhosis market?
What is the structure of clinical trial landscape by phase related to the hepatic cirrhosis market?
What is the structure of clinical trial landscape by route of administration related to the hepatic cirrhosis market?
1 PREFACE

2 SCOPE AND METHODOLOGY

2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
  2.3.1 Primary Sources
  2.3.2 Secondary Sources
2.4 Market Estimation
  2.4.1 Bottom-Up Approach
  2.4.2 Top-Down Approach
2.5 Forecasting Methodology

3 EXECUTIVE SUMMARY

4 HEPATIC CIRRHOSIS - INTRODUCTION

4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence

5 HEPATIC CIRRHOSIS - DISEASE OVERVIEW

5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment

6 PATIENT JOURNEY

7 HEPATIC CIRRHOSIS - EPIDEMIOLOGY AND PATIENT POPULATION

7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
  7.2.1 Epidemiology Scenario (2018-2023)
  7.2.2 Epidemiology Forecast (2024-2034)
  7.2.3 Epidemiology by Age (2018-2034)
  7.2.4 Epidemiology by Gender (2018-2034)
  7.2.5 Diagnosed Cases (2018-2034)
  7.2.6 Patient Pool/Treated Cases (2018-2034)
7.3 Epidemiology Scenario - United States
  7.3.1 Epidemiology Scenario (2018-2023)
  7.3.2 Epidemiology Forecast (2024-2034)
  7.3.3 Epidemiology by Age (2018-2034)
  7.3.4 Epidemiology by Gender (2018-2034)
  7.3.5 Diagnosed Cases (2018-2034)
  7.3.6 Patient Pool/Treated Cases (2018-2034)
7.4 Epidemiology Scenario - Germany
  7.4.1 Epidemiology Scenario (2018-2023)
  7.4.2 Epidemiology Forecast (2024-2034)
  7.4.3 Epidemiology by Age (2018-2034)
  7.4.4 Epidemiology by Gender (2018-2034)
  7.4.5 Diagnosed Cases (2018-2034)
  7.4.6 Patient Pool/Treated Cases (2018-2034)
7.5 Epidemiology Scenario - France
  7.5.1 Epidemiology Scenario (2018-2023)
  7.5.2 Epidemiology Forecast (2024-2034)
  7.5.3 Epidemiology by Age (2018-2034)
  7.5.4 Epidemiology by Gender (2018-2034)
  7.5.5 Diagnosed Cases (2018-2034)
  7.5.6 Patient Pool/Treated Cases (2018-2034)
7.6 Epidemiology Scenario - United Kingdom
  7.6.1 Epidemiology Scenario (2018-2023)
  7.6.2 Epidemiology Forecast (2024-2034)
  7.6.3 Epidemiology by Age (2018-2034)
  7.6.4 Epidemiology by Gender (2018-2034)
  7.6.5 Diagnosed Cases (2018-2034)
  7.6.6 Patient Pool/Treated Cases (2018-2034)
7.7 Epidemiology Scenario - Italy
  7.7.1 Epidemiology Scenario (2018-2023)
  7.7.2 Epidemiology Forecast (2024-2034)
  7.7.3 Epidemiology by Age (2018-2034)
  7.7.4 Epidemiology by Gender (2018-2034)
  7.7.5 Diagnosed Cases (2018-2034)
  7.7.6 Patient Pool/Treated Cases (2018-2034)
7.8 Epidemiology Scenario - Spain
  7.8.1 Epidemiology Scenario (2018-2023)
  7.8.2 Epidemiology Forecast (2024-2034)
  7.8.3 Epidemiology by Age (2018-2034)
  7.8.4 Epidemiology by Gender (2018-2034)
  7.8.5 Diagnosed Cases (2018-2034)
  7.8.6 Patient Pool/Treated Cases (2018-2034)
7.9 Epidemiology Scenario - Japan
  7.9.1 Epidemiology Scenario (2018-2023)
  7.9.2 Epidemiology Forecast (2024-2034)
  7.9.3 Epidemiology by Age (2018-2034)
  7.9.4 Epidemiology by Gender (2018-2034)
  7.9.5 Diagnosed Cases (2018-2034)
  7.9.6 Patient Pool/Treated Cases (2018-2034)

8 HEPATIC CIRRHOSIS - TREATMENT ALGORITHM, GUIDELINES, AND MEDICAL PRACTICES

8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm

9 HEPATIC CIRRHOSIS - UNMET NEEDS

10 HEPATIC CIRRHOSIS - KEY ENDPOINTS OF TREATMENT

11 HEPATIC CIRRHOSIS - MARKETED PRODUCTS

11.1 List of Hepatic Cirrhosis Marketed Drugs Across the Top 7 Markets
  11.1.1 Drug Name – Company Name
    11.1.1.1 Drug Overview
    11.1.1.2 Mechanism of Action
    11.1.1.3 Regulatory Status
    11.1.1.4 Clinical Trial Results
    11.1.1.5 Sales Across Major Markets
Kindly note that the complete list of marketed drugs has been provided in the report.

12 HEPATIC CIRRHOSIS - PIPELINE DRUGS

12.1 List of Hepatic Cirrhosis Pipeline Drugs Across the Top 7 Markets
  12.1.1 Zibotentan / Dapagliflozin - AstraZeneca
    12.1.1.1 Drug Overview
    12.1.1.2 Mechanism of Action
    12.1.1.3 Clinical Trial Results
    12.1.1.4 Safety and Efficacy
    12.1.1.5 Regulatory Status
  12.1.2 LPCN 1148 - Lipocine
    12.1.2.1 Drug Overview
    12.1.2.2 Mechanism of Action
    12.1.2.3 Clinical Trial Results
    12.1.2.4 Safety and Efficacy
    12.1.2.5 Regulatory Status
  12.1.3 ADR001 - Rohto Pharmaceutical
    12.1.3.1 Drug Overview
    12.1.3.2 Mechanism of Action
    12.1.3.3 Clinical Trial Results
    12.1.3.4 Safety and Efficacy
    12.1.3.5 Regulatory Status
  12.1.4 PRI 724 - Prism Pharma
    12.1.4.1 Drug Overview
    12.1.4.2 Mechanism of Action
    12.1.4.3 Clinical Trial Results
    12.1.4.4 Safety and Efficacy
    12.1.4.5 Regulatory Status
  12.1.5 BMS-986263 - Bristol-Myers Squibb
    12.1.5.1 Drug Overview
    12.1.5.2 Mechanism of Action
    12.1.5.3 Clinical Trial Results
    12.1.5.4 Safety and Efficacy
    12.1.5.5 Regulatory Status
Kindly note that the above only represents a partial list of pipeline drugs, and the complete list has been provided in the report

13 HEPATIC CIRRHOSIS - ATTRIBUTE ANALYSIS OF KEY MARKETED AND PIPELINE DRUGS

14 HEPATIC CIRRHOSIS – CLINICAL TRIAL LANDSCAPE

14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events

15 HEPATIC CIRRHOSIS - MARKET SCENARIO

15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
  15.2.1 Hepatic Cirrhosis - Market Size
    15.2.1.1 Market Size (2018-2023)
    15.2.1.2 Market Forecast (2024-2034)
  15.2.2 Hepatic Cirrhosis - Market Size by Therapies
    15.2.2.1 Market Size by Therapies (2018-2023)
    15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
  15.3.1 Hepatic Cirrhosis - Market Size
    15.3.1.1 Market Size (2018-2023)
    15.3.1.2 Market Forecast (2024-2034)
  15.3.2 Hepatic Cirrhosis - Market Size by Therapies
    15.3.2.1 Market Size by Therapies (2018-2023)
    15.3.2.2 Market Forecast by Therapies (2024-2034)
  15.3.3 Hepatic Cirrhosis - Access and Reimbursement Overview
15.4 Market Scenario - Germany
  15.4.1 Hepatic Cirrhosis - Market Size
    15.4.1.1 Market Size (2018-2023)
    15.4.1.2 Market Forecast (2024-2034)
  15.4.2 Hepatic Cirrhosis - Market Size by Therapies
    15.4.2.1 Market Size by Therapies (2018-2023)
    15.4.2.2 Market Forecast by Therapies (2024-2034)
  15.4.3 Hepatic Cirrhosis - Access and Reimbursement Overview
15.5 Market Scenario - France
  15.5.1 Hepatic Cirrhosis - Market Size
    15.5.1.1 Market Size (2018-2023)
    15.5.1.2 Market Forecast (2024-2034)
  15.5.2 Hepatic Cirrhosis - Market Size by Therapies
    15.5.2.1 Market Size by Therapies (2018-2023)
    15.5.2.2 Market Forecast by Therapies (2024-2034)
  15.5.3 Hepatic Cirrhosis - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
  15.6.1 Hepatic Cirrhosis - Market Size
    15.6.1.1 Market Size (2018-2023)
    15.6.1.2 Market Forecast (2024-2034)
  15.6.2 Hepatic Cirrhosis - Market Size by Therapies
    15.6.2.1 Market Size by Therapies (2018-2023)
    15.6.2.2 Market Forecast by Therapies (2024-2034)
  15.6.3 Hepatic Cirrhosis - Access and Reimbursement Overview
15.7 Market Scenario - Italy
  15.7.1 Hepatic Cirrhosis - Market Size
    15.7.1.1 Market Size (2018-2023)
    15.7.1.2 Market Forecast (2024-2034)
  15.7.2 Hepatic Cirrhosis - Market Size by Therapies
    15.7.2.1 Market Size by Therapies (2018-2023)
    15.7.2.2 Market Forecast by Therapies (2024-2034)
  15.7.3 Hepatic Cirrhosis - Access and Reimbursement Overview
15.8 Market Scenario - Spain
  15.8.1 Hepatic Cirrhosis - Market Size
    15.8.1.1 Market Size (2018-2023)
    15.8.1.2 Market Forecast (2024-2034)
  15.8.2 Hepatic Cirrhosis - Market Size by Therapies
    15.8.2.1 Market Size by Therapies (2018-2023)
    15.8.2.2 Market Forecast by Therapies (2024-2034)
  15.8.3 Hepatic Cirrhosis - Access and Reimbursement Overview
15.9 Market Scenario - Japan
  15.9.1 Hepatic Cirrhosis - Market Size
    15.9.1.1 Market Size (2018-2023)
    15.9.1.2 Market Forecast (2024-2034)
  15.9.2 Hepatic Cirrhosis - Market Size by Therapies
    15.9.2.1 Market Size by Therapies (2018-2023)
    15.9.2.2 Market Forecast by Therapies (2024-2034)
  15.9.3 Hepatic Cirrhosis - Access and Reimbursement Overview

16 HEPATIC CIRRHOSIS - RECENT EVENTS AND INPUTS FROM KEY OPINION LEADERS

17 HEPATIC CIRRHOSIS MARKET - SWOT ANALYSIS

17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats

18 HEPATIC CIRRHOSIS MARKET – STRATEGIC RECOMMENDATIONS

19 APPENDIX


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