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Global Spine Biologics Market Size Study & Forecast, by Product (Spinal Allografts, Bone Graft Substitutes, Cell-base Matrix), By End-use (Hospitals, Ambulatory Surgical Centers), and Regional Analysis, 2023-2030

April 2024 | 200 pages | ID: G3AB0B1417E8EN
Bizwit Research & Consulting LLP

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Global Spine Biologics Market is valued at approximately USD 2.90 billion in 2022 and is anticipated to grow with a healthy growth rate of more than 5.08% over the forecast period 2023-2030. Spine biologics are biological materials used in treating spine-related conditions, promoting healing, tissue regeneration, or stabilization. They include bone grafts, bone morphogenetic proteins (BMPs), platelet-rich plasma (PRP), and mesenchymal stem cells (MSCs). These materials enhance healing, reduce complications, and improve outcomes in spinal surgeries by stimulating bone growth, tissue repair, and regeneration. Spine biologics play a crucial role in spine fusion surgery, addressing conditions like trauma, tumours, degenerative disc disease, and spinal cord injuries. The spinal biologics market growth is being driven by factors such as the increasing prevalence of spine disorders, subsequent increase in treatment rates, and the growing awareness regarding the benefits of biologics, including minimal postoperative time and faster recovery.

Along with this, spine biologics facilitate bone growth in various stages of spine fusion procedures, prompting their increased use with rising spinal fusion surgeries. The growing elderly population is a key driver for biologics demand, with spinal disorders like spinal stenosis prevalent among individuals over 50. Ageing induces structural spine changes, intensifying the risk of spinal impairments. The Journal of Spine Surgery (JSS) stated that Spinal deformities become more prevalent with age, affecting approximately 30% to 68% of the elderly population. Also, according to the Department of Economic and Social Affairs, in 2019, the world's population of people aged 65 and up totalled 703 million. Also, the number of elderly people is expected to increase to 1.5 billion by 2050. In addition to age-related conditions, the prevalence of other spine disorders, such as scoliosis, kyphosis, and intervertebral disc degeneration, is also rising. Consequently, the increase in the risk of spinal deformities among older individuals is expected to stimulate the demand for spine biologics as spinal fusion surgeries increase globally. Thus, the increase in the geriatric population is propelling the growth of the Spine Biologics Market during the estimated period. Moreover, the increase in advancements in bone grafting procedures, as well as the rising inclination towards minimally invasive procedures present various lucrative opportunities over the forecast years. However, reimbursement issues, high bone graft costs, and ethical concerns are hampering the market growth throughout the forecast period of 2023-2030.

The key regions considered for the Global Spine Biologics Market study include Asia Pacific, North America, Europe, Latin America, and Middle East & Africa. North America dominated the market in 2022 owing to the rising inclination towards minimally invasive surgeries, and an increasing incidence of spine disorders such as disc-related issues, spinal stenosis, and spondylolisthesis. As per an article by the American Medical Association in May 2022, lumbar spinal stenosis is a prevalent issue, impacting approximately 11% of older adults in the U.S. Additionally, the presence of key industry players like Orthofix Holdings, Inc., Stryker, and NuVasive, Inc. throughout the U.S. is anticipated to bolster regional growth. Whereas Asia Pacific is expected to grow at the highest CAGR over the forecast years. The rise in the target patient population and growing awareness among patients and surgeons regarding the benefits of biologics are significantly propelling the market demand across the region. Also, the rise in the development of healthcare infrastructure, increasing healthcare spending, and a surge in the incidence of spine injuries are contributing to the region's market growth. Along with this, sedentary lifestyles and shifting behavioural patterns have led to an increased prevalence of obesity, further propelling market growth in the forecast period of 2023-2030.

Major market players included in this report are:

Stryker

NuVasive, Inc.

Orthofix

DePuy Synthes (Johnson & Johnson)

Exactech, Inc.

Zimmer Biomet

Arthrex, Inc.

Medtronic

Organogenesis Inc.

Kuros Biosciences.

Recent Developments in the Market:
  • In October 2023, Orthofix Medical Inc., a leading supplier of spine and orthopaedic solutions, unveiled the full commercial launch and 510k clearance of OsteoCove, an advanced bioactive synthetic graft designed for orthopaedic and spine procedures. OsteoCove is offered in strip and putty configurations to meet varied surgical needs.
  • In July 2023, Cerapedics Inc., a prominent bone graft provider, expanded its headquarters within the Denver metro area. This strategic expansion aims to bolster the company's diverse product portfolio, encompassing i-FACTOR bone grafts tailored for cervical spinal fusion procedures.
  • In April 2023, PUR Biologics, a subsidiary of HippoFi, Inc., launched PURcore, a bioactive moldable synthetic designed specifically for spinal surgeries.
Global Spine Biologics Market Report Scope:
  • Historical Data – 2020 - 2021
  • Base Year for Estimation – 2022
  • Forecast period - 2023-2030
  • Report Coverage - Revenue forecast, Company Ranking, Competitive Landscape, Growth factors, and Trends
  • Segments Covered - Product, End-use, Region
  • Regional Scope - North America; Europe; Asia Pacific; Latin America; Middle East & Africa
  • Customization Scope - Free report customization (equivalent to up to 8 analysts’ working hours) with purchase. Addition or alteration to country, regional & segment scope*
The objective of the study is to define the market sizes of different segments & countries in recent years and to forecast the values for the coming years. The report is designed to incorporate both qualitative and quantitative aspects of the industry within countries involved in the study.

The report also caters to detailed information about the crucial aspects such as driving factors & challenges that will define the future growth of the market. Additionally, it also incorporates potential opportunities in micro markets for stakeholders to invest along with a detailed analysis of the competitive landscape and product offerings of key players. The detailed segments and sub-segment of the market are explained below:

By Product:

Spinal Allografts

Bone Graft Substitutes

Cell-base Matrix

By End-use:

Hospitals

Ambulatory Surgical Centers

By Region:

North America

U.S.

Canada

Europe

UK

Germany

France

Spain

Italy

ROE

Asia Pacific

China

India

Japan

Australia

South Korea

RoAPAC

Latin America

Brazil

Mexico

Middle East & Africa

Saudi Arabia

South Africa

Rest of Middle East & Africa
CHAPTER 1. EXECUTIVE SUMMARY

1.1. Market Snapshot
1.2. Global & Segmental Market Estimates & Forecasts, 2020-2030 (USD Billion)
  1.2.1. Spine Biologics Market, by Region, 2020-2030 (USD Billion)
  1.2.2. Spine Biologics Market, by Product, 2020-2030 (USD Billion)
  1.2.3. Spine Biologics Market, by End-use, 2020-2030 (USD Billion)
1.3. Key Trends
1.4. Estimation Methodology
1.5. Research Assumption

CHAPTER 2. GLOBAL SPINE BIOLOGICS MARKET DEFINITION AND SCOPE

2.1. Objective of the Study
2.2. Market Definition & Scope
  2.2.1. Industry Evolution
  2.2.2. Scope of the Study
2.3. Years Considered for the Study
2.4. Currency Conversion Rates

CHAPTER 3. GLOBAL SPINE BIOLOGICS MARKET DYNAMICS

3.1. Spine Biologics Market Impact Analysis (2020-2030)
  3.1.1. Market Drivers
    3.1.1.1. Increase in geriatric population
    3.1.1.2. Rising prevalence of spine disorders
  3.1.2. Market Challenges
    3.1.2.1. Reimbursement issues
    3.1.2.2. High cost of bone graft procedures
  3.1.3. Market Opportunities
    3.1.3.1. Increase in advancements in bone grafting procedures
    3.1.3.2. Rising inclination towards minimally invasive procedures

CHAPTER 4. GLOBAL SPINE BIOLOGICS MARKET INDUSTRY ANALYSIS

4.1. Porter’s 5 Force Model
  4.1.1. Bargaining Power of Suppliers
  4.1.2. Bargaining Power of Buyers
  4.1.3. Threat of New Entrants
  4.1.4. Threat of Substitutes
  4.1.5. Competitive Rivalry
4.2. Porter’s 5 Force Impact Analysis
4.3. PEST Analysis
  4.3.1. Political
  4.3.2. Economical
  4.3.3. Social
  4.3.4. Technological
  4.3.5. Environmental
  4.3.6. Legal
4.4. Top investment opportunity
4.5. Top winning strategies
4.6. COVID-19 Impact Analysis
4.7. Disruptive Trends
4.8. Industry Expert Perspective
4.9. Analyst Recommendation & Conclusion

CHAPTER 5. GLOBAL SPINE BIOLOGICS MARKET, BY PRODUCT

5.1. Market Snapshot
5.2. Global Spine Biologics Market by Product, Performance - Potential Analysis
5.3. Global Spine Biologics Market Estimates & Forecasts by Product 2020-2030 (USD Billion)
5.4. Spine Biologics Market, Sub Segment Analysis
  5.4.1. Spinal Allografts
  5.4.2. Bone Graft Substitutes
  5.4.3. Cell-base Matrix

CHAPTER 6. GLOBAL SPINE BIOLOGICS MARKET, BY END-USE

6.1. Market Snapshot
6.2. Global Spine Biologics Market by End-use, Performance - Potential Analysis
6.3. Global Spine Biologics Market Estimates & Forecasts by End-use 2020-2030 (USD Billion)
6.4. Spine Biologics Market, Sub Segment Analysis
  6.4.1. Hospitals
  6.4.2. Ambulatory Surgical Centers

CHAPTER 7. GLOBAL SPINE BIOLOGICS MARKET, REGIONAL ANALYSIS

7.1. Top Leading Countries
7.2. Top Emerging Countries
7.3. Spine Biologics Market, Regional Market Snapshot
7.4. North America Spine Biologics Market
  7.4.1. U.S. Spine Biologics Market
    7.4.1.1. Product breakdown estimates & forecasts, 2020-2030
    7.4.1.2. End-use breakdown estimates & forecasts, 2020-2030
  7.4.2. Canada Spine Biologics Market
7.5. Europe Spine Biologics Market Snapshot
  7.5.1. U.K. Spine Biologics Market
  7.5.2. Germany Spine Biologics Market
  7.5.3. France Spine Biologics Market
  7.5.4. Spain Spine Biologics Market
  7.5.5. Italy Spine Biologics Market
  7.5.6. Rest of Europe Spine Biologics Market
7.6. Asia-Pacific Spine Biologics Market Snapshot
  7.6.1. China Spine Biologics Market
  7.6.2. India Spine Biologics Market
  7.6.3. Japan Spine Biologics Market
  7.6.4. Australia Spine Biologics Market
  7.6.5. South Korea Spine Biologics Market
  7.6.6. Rest of Asia Pacific Spine Biologics Market
7.7. Latin America Spine Biologics Market Snapshot
  7.7.1. Brazil Spine Biologics Market
  7.7.2. Mexico Spine Biologics Market
7.8. Middle East & Africa Spine Biologics Market
  7.8.1. Saudi Arabia Spine Biologics Market
  7.8.2. South Africa Spine Biologics Market
  7.8.3. Rest of Middle East & Africa Spine Biologics Market

CHAPTER 8. COMPETITIVE INTELLIGENCE

8.1. Key Company SWOT Analysis
  8.1.1. Company
  8.1.2. Company
  8.1.3. Company
8.2. Top Market Strategies
8.3. Company Profiles
  8.3.1. Stryker
    8.3.1.1. Key Information
    8.3.1.2. Overview
    8.3.1.3. Financial (Subject to Data Availability)
    8.3.1.4. Product Summary
    8.3.1.5. Recent Developments
  8.3.2. NuVasive, Inc.
  8.3.3. Orthofix
  8.3.4. DePuy Synthes (Johnson & Johnson)
  8.3.5. Exactech, Inc.
  8.3.6. Zimmer Biomet
  8.3.7. Arthrex, Inc.
  8.3.8. Medtronic
  8.3.9. Organogenesis Inc.
  8.3.10. Kuros Biosciences.

CHAPTER 9. RESEARCH PROCESS

9.1. Research Process
  9.1.1. Data Mining
  9.1.2. Analysis
  9.1.3. Market Estimation
  9.1.4. Validation
  9.1.5. Publishing
9.2. Research Attributes
9.3. Research Assumption

12 .LIST OF TABLES

TABLE 1. Global Spine Biologics Market, report scope
TABLE 2. Global Spine Biologics Market estimates & forecasts by Region 2020-2030 (USD Billion)
TABLE 3. Global Spine Biologics Market estimates & forecasts by Product 2020-2030 (USD Billion)
TABLE 4. Global Spine Biologics Market estimates & forecasts by End-use 2020-2030 (USD Billion)
TABLE 5. Global Spine Biologics Market by segment, estimates & forecasts, 2020-2030 (USD Billion)
TABLE 6. Global Spine Biologics Market by region, estimates & forecasts, 2020-2030 (USD Billion)
TABLE 7. Global Spine Biologics Market by segment, estimates & forecasts, 2020-2030 (USD Billion)
TABLE 8. Global Spine Biologics Market by region, estimates & forecasts, 2020-2030 (USD Billion)
TABLE 9. Global Spine Biologics Market by segment, estimates & forecasts, 2020-2030 (USD Billion)
TABLE 10. Global Spine Biologics Market by region, estimates & forecasts, 2020-2030 (USD Billion)
TABLE 11. Global Spine Biologics Market by segment, estimates & forecasts, 2020-2030 (USD Billion)
TABLE 12. Global Spine Biologics Market by region, estimates & forecasts, 2020-2030 (USD Billion)
TABLE 13. Global Spine Biologics Market by segment, estimates & forecasts, 2020-2030 (USD Billion)
TABLE 14. Global Spine Biologics Market by region, estimates & forecasts, 2020-2030 (USD Billion)
TABLE 15. U.S. Spine Biologics Market estimates & forecasts, 2020-2030 (USD Billion)
TABLE 16. U.S. Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 17. U.S. Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 18. Canada Spine Biologics Market estimates & forecasts, 2020-2030 (USD Billion)
TABLE 19. Canada Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 20. Canada Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 21. UK Spine Biologics Market estimates & forecasts, 2020-2030 (USD Billion)
TABLE 22. UK Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 23. UK Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 24. Germany Spine Biologics Market estimates & forecasts, 2020-2030 (USD Billion)
TABLE 25. Germany Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 26. Germany Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 27. France Spine Biologics Market estimates & forecasts, 2020-2030 (USD Billion)
TABLE 28. France Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 29. France Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 30. Italy Spine Biologics Market estimates & forecasts, 2020-2030 (USD Billion)
TABLE 31. Italy Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 32. Italy Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 33. Spain Spine Biologics Market estimates & forecasts, 2020-2030 (USD Billion)
TABLE 34. Spain Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 35. Spain Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 36. RoE Spine Biologics Market estimates & forecasts, 2020-2030 (USD Billion)
TABLE 37. RoE Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 38. RoE Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 39. China Spine Biologics Market estimates & forecasts, 2020-2030 (USD Billion)
TABLE 40. China Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 41. China Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 42. India Spine Biologics Market estimates & forecasts, 2020-2030 (USD Billion)
TABLE 43. India Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 44. India Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 45. Japan Spine Biologics Market estimates & forecasts, 2020-2030 (USD Billion)
TABLE 46. Japan Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 47. Japan Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 48. South Korea Spine Biologics Market estimates & forecasts, 2020-2030 (USD Billion)
TABLE 49. South Korea Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 50. South Korea Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 51. Australia Spine Biologics Market estimates & forecasts, 2020-2030 (USD Billion)
TABLE 52. Australia Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 53. Australia Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 54. RoAPAC Spine Biologics Market estimates & forecasts, 2020-2030 (USD Billion)
TABLE 55. RoAPAC Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 56. RoAPAC Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 57. Brazil Spine Biologics Market estimates & forecasts, 2020-2030 (USD Billion)
TABLE 58. Brazil Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 59. Brazil Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 60. Mexico Spine Biologics Market estimates & forecasts, 2020-2030 (USD Billion)
TABLE 61. Mexico Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 62. Mexico Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 63. RoLA Spine Biologics Market estimates & forecasts, 2020-2030 (USD Billion)
TABLE 64. RoLA Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 65. RoLA Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 66. Saudi Arabia Spine Biologics Market estimates & forecasts, 2020-2030 (USD Billion)
TABLE 67. South Africa Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 68. RoMEA Spine Biologics Market estimates & forecasts by segment 2020-2030 (USD Billion)
TABLE 69. List of secondary sources, used in the study of global Spine Biologics Market
TABLE 70. List of primary sources, used in the study of global Spine Biologics Market
TABLE 71. Years considered for the study
TABLE 72. Exchange rates considered
List of tables and figures and dummy in nature, final lists may vary in the final deliverable

LIST OF FIGURES

FIG 1. Global Spine Biologics Market, research methodology
FIG 2. Global Spine Biologics Market, Market estimation techniques
FIG 3. Global Market size estimates & forecast methods
FIG 4. Global Spine Biologics Market, key trends 2022
FIG 5. Global Spine Biologics Market, growth prospects 2023-2030
FIG 6. Global Spine Biologics Market, porters 5 force model
FIG 7. Global Spine Biologics Market, pest analysis
FIG 8. Global Spine Biologics Market, value chain analysis
FIG 9. Global Spine Biologics Market by segment, 2020 & 2030 (USD Billion)
FIG 10. Global Spine Biologics Market by segment, 2020 & 2030 (USD Billion)
FIG 11. Global Spine Biologics Market by segment, 2020 & 2030 (USD Billion)
FIG 12. Global Spine Biologics Market by segment, 2020 & 2030 (USD Billion)
FIG 13. Global Spine Biologics Market by segment, 2020 & 2030 (USD Billion)
FIG 14. Global Spine Biologics Market, regional snapshot 2020 & 2030
FIG 15. North America Spine Biologics Market 2020 & 2030 (USD Billion)
FIG 16. Europe Spine Biologics Market 2020 & 2030 (USD Billion)
FIG 17. Asia Pacific Spine Biologics Market 2020 & 2030 (USD Billion)
FIG 18. Latin America Spine Biologics Market 2020 & 2030 (USD Billion)
FIG 19. Middle East & Africa Spine Biologics Market 2020 & 2030 (USD Billion)
List of tables and figures and dummy in nature, final lists may vary in the final deliverable


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