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Global Spinal Muscular Atrophy Treatment Market Size study & Forecast, by Product (Nusinersen, Onasemnogen Abeparvovec), by Disease Type (Type 1 SMA, Type 2 SMA, Others), by Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Others) and Regional Analysis, 2022-2029

January 2023 | 200 pages | ID: G332644C705AEN
Bizwit Research & Consulting LLP

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Global Spinal Muscular Atrophy Treatment Market is valued at approximately USD 3.88 billion in 2021 and is anticipated to grow with a healthy growth rate of more than 18.6% over the forecast period 2022-2029. Spinal muscular atrophy (SMA) is a type of genetic disease that gradually destroys motor neurons that are the spinal cord and nerve cells in the brain stem. It also affects vital skeletal muscle activity including breathing, walking, speaking, and swallowing, which leads to muscle weakness and atrophy. The growing awareness regarding novel therapies, rising government support, coupled with increasing healthcare expenditure is primary factors that are fostering market growth across the globe.

The prevalence of spinal muscular atrophy is on the rise which is directly associated with the market demand across the globe. The National Organization for Rare Disorders (NORD) estimates that approximately 1 in 10,000 people worldwide suffer with spinal muscular atrophy (SMA). Likewise, according to the Spinal Muscular Atrophy Foundation, the condition is expected to affect 1 in every 6,000 to 10,000 newborns worldwide. Therefore, the growing incidences of the disorder are actively contributing to market demand, which, in turn, fosters the growth of the market. Moreover, the introduction of new product with high efficacies, as well as growing R&D investments are presenting various lucrative opportunities over the forecasting years. However, the high costs associated with the approved products and the dearth of skilled professionals are restricting the market growth throughout the forecast period of 2022-2029.

The key regions considered for the Global Spinal Muscular Atrophy Treatment Market study include Asia Pacific, North America, Europe, Latin America, and the Rest of the World. North America dominated the market in terms of revenue, owing to the growing spending on treatment products and the rising incidence of SMA disorders among the population. Whereas, the Asia Pacific is also expected to grow with the highest CAGR during the forecast period, owing to factors such as rising target populations, increasing expenditure on healthcare services, and geographic expansion of key players in the market space.

Major market players included in this report are:
Biogen
Novartis AG
Ionis Pharmaceuticals Inc.
Biohaven Pharmaceuticals
F. Hoffmann-La Roche Ltd
Cytokinetics
Scholar Rock, Inc.
PTC Therapeutics
NMD PHARMA A/S
Astellas Pharma Inc.

Recent Developments in the Market:
In January 2022, Biogen and Ionis Pharmaceuticals, Inc., declare that the companies entered into licensing agreement with the aim of developing another experimental drug BIIB115 (an antisense oligonucleotide) to cure of patients with SMA. BIIB115 is an experimental preclinical-stage drug. The objective of this agreement is to expand Biogen’s SMA drug portfolio.
In May 2019, Novartis AG announced that its Zolgensma (onasemnogene abeparvovec-xioi) received an approval from the U.S. FDA for the first and only gene therapy for pediatric patients with spinal muscular atrophy (SMA).

Global Spinal Muscular Atrophy Treatment Market Report Scope:
Historical Data 2019-2020-2021
Base Year for Estimation 2021
Forecast period 2022-2029
Report Coverage Revenue forecast, Company Ranking, Competitive Landscape, Growth factors, and Trends
Segments Covered Product, Disease Type, Distribution Channel, Region
Regional Scope North America; Europe; Asia Pacific; Latin America; Rest of the World
Customization Scope Free report customization (equivalent up to 8 analyst’s working hours) with purchase. Addition or alteration to country, regional & segment scope*

The objective of the study is to define market sizes of different segments & countries in recent years and to forecast the values to the coming years. The report is designed to incorporate both qualitative and quantitative aspects of the industry within countries involved in the study.

The report also caters detailed information about the crucial aspects such as driving factors & challenges which will define the future growth of the market. Additionally, it also incorporates potential opportunities in micro markets for stakeholders to invest along with the detailed analysis of competitive landscape and product offerings of key players. The detailed segments and sub-segment of the market are explained below:

By Product:
Nusinersen
Onasemnogen Abeparvovec
By Disease Type:
Type 1 SMA
Type 2 SMA
Others
By Distribution Channel:
Hospital Pharmacies
Retail Pharmacies
Others
By Region:
North America
U.S.
Canada
Europe
UK
Germany
France
Spain
Italy
ROE
Asia Pacific
China
India
Japan
Australia
South Korea
RoAPAC
Latin America
Brazil
Mexico
RoLA
Rest of the World

CHAPTER 1. EXECUTIVE SUMMARY

1.1. Market Snapshot
1.2. Global & Segmental Market Estimates & Forecasts, 2019-2029 (USD Billion)
  1.2.1. Spinal Muscular Atrophy Treatment Market, by Region, 2019-2029 (USD Billion)
  1.2.2. Spinal Muscular Atrophy Treatment Market, by Product, 2019-2029 (USD Billion)
  1.2.3. Spinal Muscular Atrophy Treatment Market, by Disease Type, 2019-2029 (USD Billion)
  1.2.4. Spinal Muscular Atrophy Treatment Market, by Distribution Channel, 2019-2029 (USD Billion)
1.3. Key Trends
1.4. Estimation Methodology
1.5. Research Assumption

CHAPTER 2. GLOBAL SPINAL MUSCULAR ATROPHY TREATMENT MARKET DEFINITION AND SCOPE

2.1. Objective of the Study
2.2. Market Definition & Scope
  2.2.1. Scope of the Study
  2.2.2. Industry Evolution
2.3. Years Considered for the Study
2.4. Currency Conversion Rates

CHAPTER 3. GLOBAL SPINAL MUSCULAR ATROPHY TREATMENT MARKET DYNAMICS

3.1. Spinal Muscular Atrophy Treatment Market Impact Analysis (2019-2029)
  3.1.1. Market Drivers
    3.1.1.1. Increasing awareness regarding novel therapies
    3.1.1.2. Growing prevalence of spinal muscular atrophy
  3.1.2. Market Challenges
    3.1.2.1. High costs associated with the approved products
    3.1.2.2. Dearth of skilled professionals
  3.1.3. Market Opportunities
    3.1.3.1. Introduction of new product with high efficacies
    3.1.3.2. Growing R&D investments

CHAPTER 4. GLOBAL SPINAL MUSCULAR ATROPHY TREATMENT MARKET INDUSTRY ANALYSIS

4.1. Porter’s 5 Force Model
  4.1.1. Bargaining Power of Suppliers
  4.1.2. Bargaining Power of Buyers
  4.1.3. Threat of New Entrants
  4.1.4. Threat of Substitutes
  4.1.5. Competitive Rivalry
4.2. Futuristic Approach to Porter’s 5 Force Model (2019-2029)
4.3. PEST Analysis
  4.3.1. Political
  4.3.2. Economical
  4.3.3. Social
  4.3.4. Technological
4.4. Top investment opportunity
4.5. Top winning strategies
4.6. Industry Experts Prospective
4.7. Analyst Recommendation & Conclusion

CHAPTER 5. RISK ASSESSMENT: COVID-19 IMPACT

5.1. Assessment of the overall impact of COVID-19 on the industry
5.2. Pre COVID-19 and post COVID-19 Market scenario

CHAPTER 6. GLOBAL SPINAL MUSCULAR ATROPHY TREATMENT MARKET, BY PRODUCT

6.1. Market Snapshot
6.2. Global Spinal Muscular Atrophy Treatment Market by Product, Performance - Potential Analysis
6.3. Global Spinal Muscular Atrophy Treatment Market Estimates & Forecasts by Product 2019-2029 (USD Billion)
6.4. Spinal Muscular Atrophy Treatment Market, Sub Segment Analysis
  6.4.1. Nusinersen
  6.4.2. Onasemnogen Abeparvovec

CHAPTER 7. GLOBAL SPINAL MUSCULAR ATROPHY TREATMENT MARKET, BY DISEASE TYPE

7.1. Market Snapshot
7.2. Global Spinal Muscular Atrophy Treatment Market by Disease Type, Performance - Potential Analysis
7.3. Global Spinal Muscular Atrophy Treatment Market Estimates & Forecasts by Disease Type 2019-2029 (USD Billion)
7.4. Spinal Muscular Atrophy Treatment Market, Sub Segment Analysis
  7.4.1. Type 1 SMA
  7.4.2. Type 2 SMA
  7.4.3. Others

CHAPTER 8. GLOBAL SPINAL MUSCULAR ATROPHY TREATMENT MARKET, BY DISTRIBUTION CHANNEL

8.1. Market Snapshot
8.2. Global Spinal Muscular Atrophy Treatment Market by Distribution Channel, Performance - Potential Analysis
8.3. Global Spinal Muscular Atrophy Treatment Market Estimates & Forecasts by Distribution Channel 2019-2029 (USD Billion)
8.4. Spinal Muscular Atrophy Treatment Market, Sub Segment Analysis
  8.4.1. Hospital Pharmacies
  8.4.2. Retail Pharmacies
  8.4.3. Others

CHAPTER 9. GLOBAL SPINAL MUSCULAR ATROPHY TREATMENT MARKET, REGIONAL ANALYSIS

9.1. Spinal Muscular Atrophy Treatment Market, Regional Market Snapshot
9.2. North America Spinal Muscular Atrophy Treatment Market
  9.2.1. U.S. Spinal Muscular Atrophy Treatment Market
    9.2.1.1. Product breakdown estimates & forecasts, 2019-2029
    9.2.1.2. Disease Type breakdown estimates & forecasts, 2019-2029
    9.2.1.3. Distribution Channel breakdown estimates & forecasts, 2019-2029
  9.2.2. Canada Spinal Muscular Atrophy Treatment Market
9.3. Europe Spinal Muscular Atrophy Treatment Market Snapshot
  9.3.1. U.K. Spinal Muscular Atrophy Treatment Market
  9.3.2. Germany Spinal Muscular Atrophy Treatment Market
  9.3.3. France Spinal Muscular Atrophy Treatment Market
  9.3.4. Spain Spinal Muscular Atrophy Treatment Market
  9.3.5. Italy Spinal Muscular Atrophy Treatment Market
  9.3.6. Rest of Europe Spinal Muscular Atrophy Treatment Market
9.4. Asia-Pacific Spinal Muscular Atrophy Treatment Market Snapshot
  9.4.1. China Spinal Muscular Atrophy Treatment Market
  9.4.2. India Spinal Muscular Atrophy Treatment Market
  9.4.3. Japan Spinal Muscular Atrophy Treatment Market
  9.4.4. Australia Spinal Muscular Atrophy Treatment Market
  9.4.5. South Korea Spinal Muscular Atrophy Treatment Market
  9.4.6. Rest of Asia Pacific Spinal Muscular Atrophy Treatment Market
9.5. Latin America Spinal Muscular Atrophy Treatment Market Snapshot
  9.5.1. Brazil Spinal Muscular Atrophy Treatment Market
  9.5.2. Mexico Spinal Muscular Atrophy Treatment Market
  9.5.3. Rest of Latin America Spinal Muscular Atrophy Treatment Market
9.6. Rest of The World Spinal Muscular Atrophy Treatment Market

CHAPTER 10. COMPETITIVE INTELLIGENCE

10.1. Top Market Strategies
10.2. Company Profiles
  10.2.1. Biogen
    10.2.1.1. Key Information
    10.2.1.2. Overview
    10.2.1.3. Financial (Subject to Data Availability)
    10.2.1.4. Product Summary
    10.2.1.5. Recent Developments
  10.2.2. Novartis AG
  10.2.3. Ionis Pharmaceuticals Inc.
  10.2.4. Biohaven Pharmaceuticals
  10.2.5. F. Hoffmann-La Roche Ltd
  10.2.6. Cytokinetics
  10.2.7. Scholar Rock, Inc.
  10.2.8. PTC Therapeutics
  10.2.9. NMD PHARMA A/S
  10.2.10. Astellas Pharma Inc.

CHAPTER 11. RESEARCH PROCESS

11.1. Research Process
  11.1.1. Data Mining
  11.1.2. Analysis
  11.1.3. Market Estimation
  11.1.4. Validation
  11.1.5. Publishing
11.2. Research Attributes
11.3. Research Assumption

LIST OF TABLES

TABLE 1. Global Spinal Muscular Atrophy Treatment Market, report scope
TABLE 2. Global Spinal Muscular Atrophy Treatment Market estimates & forecasts by Region 2019-2029 (USD Billion)
TABLE 3. Global Spinal Muscular Atrophy Treatment Market estimates & forecasts by Product 2019-2029 (USD Billion)
TABLE 4. Global Spinal Muscular Atrophy Treatment Market estimates & forecasts by Disease Type 2019-2029 (USD Billion)
TABLE 5. Global Spinal Muscular Atrophy Treatment Market estimates & forecasts by Distribution Channel 2019-2029 (USD Billion)
TABLE 6. Global Spinal Muscular Atrophy Treatment Market by segment, estimates & forecasts, 2019-2029 (USD Billion)
TABLE 7. Global Spinal Muscular Atrophy Treatment Market by region, estimates & forecasts, 2019-2029 (USD Billion)
TABLE 8. Global Spinal Muscular Atrophy Treatment Market by segment, estimates & forecasts, 2019-2029 (USD Billion)
TABLE 9. Global Spinal Muscular Atrophy Treatment Market by region, estimates & forecasts, 2019-2029 (USD Billion)
TABLE 10. Global Spinal Muscular Atrophy Treatment Market by segment, estimates & forecasts, 2019-2029 (USD Billion)
TABLE 11. Global Spinal Muscular Atrophy Treatment Market by region, estimates & forecasts, 2019-2029 (USD Billion)
TABLE 12. Global Spinal Muscular Atrophy Treatment Market by segment, estimates & forecasts, 2019-2029 (USD Billion)
TABLE 13. Global Spinal Muscular Atrophy Treatment Market by region, estimates & forecasts, 2019-2029 (USD Billion)
TABLE 14. Global Spinal Muscular Atrophy Treatment Market by segment, estimates & forecasts, 2019-2029 (USD Billion)
TABLE 15. Global Spinal Muscular Atrophy Treatment Market by region, estimates & forecasts, 2019-2029 (USD Billion)
TABLE 16. U.S. Spinal Muscular Atrophy Treatment Market estimates & forecasts, 2019-2029 (USD Billion)
TABLE 17. U.S. Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 18. U.S. Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 19. Canada Spinal Muscular Atrophy Treatment Market estimates & forecasts, 2019-2029 (USD Billion)
TABLE 20. Canada Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 21. Canada Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 22. UK Spinal Muscular Atrophy Treatment Market estimates & forecasts, 2019-2029 (USD Billion)
TABLE 23. UK Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 24. UK Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 25. Germany Spinal Muscular Atrophy Treatment Market estimates & forecasts, 2019-2029 (USD Billion)
TABLE 26. Germany Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 27. Germany Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 28. France Spinal Muscular Atrophy Treatment Market estimates & forecasts, 2019-2029 (USD Billion)
TABLE 29. France Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 30. France Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 31. Italy Spinal Muscular Atrophy Treatment Market estimates & forecasts, 2019-2029 (USD Billion)
TABLE 32. Italy Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 33. Italy Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 34. Spain Spinal Muscular Atrophy Treatment Market estimates & forecasts, 2019-2029 (USD Billion)
TABLE 35. Spain Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 36. Spain Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 37. RoE Spinal Muscular Atrophy Treatment Market estimates & forecasts, 2019-2029 (USD Billion)
TABLE 38. RoE Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 39. RoE Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 40. China Spinal Muscular Atrophy Treatment Market estimates & forecasts, 2019-2029 (USD Billion)
TABLE 41. China Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 42. China Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 43. India Spinal Muscular Atrophy Treatment Market estimates & forecasts, 2019-2029 (USD Billion)
TABLE 44. India Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 45. India Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 46. Japan Spinal Muscular Atrophy Treatment Market estimates & forecasts, 2019-2029 (USD Billion)
TABLE 47. Japan Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 48. Japan Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 49. South Korea Spinal Muscular Atrophy Treatment Market estimates & forecasts, 2019-2029 (USD Billion)
TABLE 50. South Korea Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 51. South Korea Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 52. Australia Spinal Muscular Atrophy Treatment Market estimates & forecasts, 2019-2029 (USD Billion)
TABLE 53. Australia Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 54. Australia Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 55. RoAPAC Spinal Muscular Atrophy Treatment Market estimates & forecasts, 2019-2029 (USD Billion)
TABLE 56. RoAPAC Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 57. RoAPAC Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 58. Brazil Spinal Muscular Atrophy Treatment Market estimates & forecasts, 2019-2029 (USD Billion)
TABLE 59. Brazil Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 60. Brazil Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 61. Mexico Spinal Muscular Atrophy Treatment Market estimates & forecasts, 2019-2029 (USD Billion)
TABLE 62. Mexico Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 63. Mexico Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 64. RoLA Spinal Muscular Atrophy Treatment Market estimates & forecasts, 2019-2029 (USD Billion)
TABLE 65. RoLA Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 66. RoLA Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 67. Row Spinal Muscular Atrophy Treatment Market estimates & forecasts, 2019-2029 (USD Billion)
TABLE 68. Row Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 69. Row Spinal Muscular Atrophy Treatment Market estimates & forecasts by segment 2019-2029 (USD Billion)
TABLE 70. List of secondary sources, used in the study of global Spinal Muscular Atrophy Treatment Market
TABLE 71. List of primary sources, used in the study of global Spinal Muscular Atrophy Treatment Market
TABLE 72. Years considered for the study
TABLE 73. Exchange rates considered
List of tables and figures and dummy in nature, final lists may vary in the final deliverable

LIST OF FIGURES

FIG 1. Global Spinal Muscular Atrophy Treatment Market, research methodology
FIG 2. Global Spinal Muscular Atrophy Treatment Market, Market estimation techniques
FIG 3. Global Market size estimates & forecast methods
FIG 4. Global Spinal Muscular Atrophy Treatment Market, key trends 2021
FIG 5. Global Spinal Muscular Atrophy Treatment Market, growth prospects 2022-2029
FIG 6. Global Spinal Muscular Atrophy Treatment Market, porters 5 force model
FIG 7. Global Spinal Muscular Atrophy Treatment Market, pest analysis
FIG 8. Global Spinal Muscular Atrophy Treatment Market, value chain analysis
FIG 9. Global Spinal Muscular Atrophy Treatment Market by segment, 2019 & 2029 (USD Billion)
FIG 10. Global Spinal Muscular Atrophy Treatment Market by segment, 2019 & 2029 (USD Billion)
FIG 11. Global Spinal Muscular Atrophy Treatment Market by segment, 2019 & 2029 (USD Billion)
FIG 12. Global Spinal Muscular Atrophy Treatment Market by segment, 2019 & 2029 (USD Billion)
FIG 13. Global Spinal Muscular Atrophy Treatment Market by segment, 2019 & 2029 (USD Billion)
FIG 14. Global Spinal Muscular Atrophy Treatment Market, regional snapshot 2019 & 2029
FIG 15. North America Spinal Muscular Atrophy Treatment Market 2019 & 2029 (USD Billion)
FIG 16. Europe Spinal Muscular Atrophy Treatment Market 2019 & 2029 (USD Billion)
FIG 17. Asia pacific Spinal Muscular Atrophy Treatment Market 2019 & 2029 (USD Billion)
FIG 18. Latin America Spinal Muscular Atrophy Treatment Market 2019 & 2029 (USD Billion)
FIG 19. Global Spinal Muscular Atrophy Treatment Market, company Market share analysis (2021)
List of tables and figures and dummy in nature, final lists may vary in the final deliverable













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