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Global Difficult-to-Express Proteins Market Size study, By Protein (Proteases, Kinases, Membrane Proteins, Others), By Technology (Cell-free Protein Synthesis, Prokaryotic Expression Systems, SUMO Fusion System, Gene Fusion Systems, Others), By Application (Drug Discovery, Protein Purification, Protein Therapeutics, Disease Diagnostics and Monitoring, Others), and Regional Forecasts 2022-2028

June 2022 | 200 pages | ID: G4366BC5D349EN
Bizwit Research & Consulting LLP

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Global Difficult-to-Express Proteins Market is valued approximately USD XX million in 2021 and is anticipated to grow with a healthy growth rate of more than XX % over the forecast period 2022-2028. The Difficult-to-Express Proteins can be defined as proteins that cannot be easily synthesized in conventional in vivo protein production platforms. These proteins do not emerge in fully soluble, well-folded, and active form in a heterologous expression system due to their inherent properties. Proteins such as proteases, kinases, membrane proteins are considered as difficult to express proteins. The growing prevalence of chronic diseases and increasing end use applications of difficult-to-express proteins as well as recent clinical trials towards high proteins are accelerating the global market demand. For instance, according to World Health Organization (WHO) estimate – as of 2019, globally around 17.9 million people succumbs to cardiovascular diseases (CVDs), witnessing for 32% of all global deaths. Further, 85% of death were caused by heart attack and stroke. Moreover, in October 2021, Germany based Eleva, a leading manufacturer of superior biologics announced clinical development of Difficult-To-Express high-potential proteins. The company would produce complex proteins for future therapies, such as 2nd generation oncological therapeutics, and virus-like-particles (VLP) for vaccine development. Also, growing investment towards healthcare research and rising healthcare sector in emerging economics are anticipated to act as a catalyzing factor for the market demand during the forecast period. However, a high cost associated with these proteins impede the growth of the market over the forecast period of 2022-2028.

The key regions considered for the global Difficult-to-Express Proteins Market study include Asia Pacific, North America, Europe, Latin America, and the Rest of the World. North America is the leading region across the world in terms of market share owing to the growing spending on healthcare research activities and presence of leading pharma players in the region. Whereas, Asia Pacific is anticipated to exhibit a significant growth rate over the forecast period 2022-2028. Factors such as the thriving growth of clinical research organizations and increasing penetration of leading market players in the region, would create lucrative growth prospects for the global Difficult-to-Express Proteins Market across the Asia Pacific region.

Major market players included in this report are:
R&D Systems
Enzo Life Sciences
Sino Biological
Thermo Fisher Scientific
StressMarq Biosciences
LifeSensors Inc.
Lucigen
Batavia Biosciences Inc.
WuXi Biologics
Selexis SA

The objective of the study is to define market sizes of different segments & countries in recent years and to forecast the values to the coming eight years. The report is designed to incorporate both qualitative and quantitative aspects of the industry within each of the regions and countries involved in the study. Furthermore, the report also caters the detailed information about the crucial aspects such as driving factors & challenges which will define the future growth of the market. Additionally, the report shall also incorporate available opportunities in micro markets for stakeholders to invest along with the detailed analysis of competitive landscape and product offerings of key players. The detailed segments and sub-segment of the market are explained below:
By Protein
Proteases
Kinases
Membrane Proteins
Others
By Technology
Cell-free Protein Synthesis
Prokaryotic Expression Systems
SUMO Fusion System
Gene Fusion Systems
Others
By Application
Drug Discovery
Protein Purification
Protein Therapeutics
Disease Diagnostics and Monitoring
Others
By Region:
North America
U.S.
Canada
Europe
UK
Germany
France
Spain
Italy
ROE

Asia Pacific
China
India
Japan
Australia
South Korea
RoAPAC
Latin America
Brazil
Mexico
Rest of the World

Furthermore, years considered for the study are as follows:

Historical year – 2018, 2019, 2020
Base year – 2021
Forecast period – 2022 to 2028

Target Audience of the Global Difficult-to-Express Proteins Market in Market Study:

Key Consulting Companies & Advisors
Large, medium-sized, and small enterprises
Venture capitalists
Value-Added Resellers (VARs)
Third-party knowledge providers
Investment bankers
Investors

CHAPTER 1. EXECUTIVE SUMMARY

1.1. Market Snapshot
1.2. Global & Segmental Market Estimates & Forecasts, 2020-2028 (USD Million)
  1.2.1. Global Difficult-to-Express Proteins Market, by Region, 2020-2028 (USD Million)
  1.2.2. Global Difficult-to-Express Proteins Market, by Protein, 2020-2028 (USD Million)
  1.2.3. Global Difficult-to-Express Proteins Market, by Technology, 2020-2028 (USD Million)
  1.2.4. Global Difficult-to-Express Proteins Market, by Application, 2020-2028 (USD Million)
1.3. Key Trends
1.4. Estimation Methodology
1.5. Research Assumption

CHAPTER 2. GLOBAL DIFFICULT-TO-EXPRESS PROTEINS MARKET DEFINITION AND SCOPE

2.1. Objective of the Study
2.2. Market Definition & Scope
  2.2.1. Scope of the Study
  2.2.2. Industry Evolution
2.3. Years Considered for the Study
2.4. Currency Conversion Rates

CHAPTER 3. GLOBAL DIFFICULT-TO-EXPRESS PROTEINS MARKET DYNAMICS

3.1. Difficult-to-Express Proteins Market Impact Analysis (2020-2028)
  3.1.1. Market Drivers
    3.1.1.1. Growing prevalence of chronic diseases.
    3.1.1.2. Increasing end use applications of difficult-to-express proteins.
    3.1.1.3. Recent clinical trials towards high proteins.
  3.1.2. Market Challenges
    3.1.2.1. High cost associated with these proteins.
  3.1.3. Market Opportunities
    3.1.3.1. Growing investment towards healthcare research.
    3.1.3.2. Rising healthcare sector in emerging economics.

CHAPTER 4. GLOBAL DIFFICULT-TO-EXPRESS PROTEINS MARKET INDUSTRY ANALYSIS

4.1. Porter’s 5 Force Model
  4.1.1. Bargaining Power of Suppliers
  4.1.2. Bargaining Power of Buyers
  4.1.3. Threat of New Entrants
  4.1.4. Threat of Substitutes
  4.1.5. Competitive Rivalry
  4.1.6. Futuristic Approach to Porter’s 5 Force Model (2018-2028)
4.2. PEST Analysis
  4.2.1. Political
  4.2.2. Economical
  4.2.3. Social
  4.2.4. Technological
4.3. Investment Adoption Model
4.4. Analyst Recommendation & Conclusion
4.5. Top investment opportunity
4.6. Top winning strategies

CHAPTER 5. RISK ASSESSMENT: COVID-19 IMPACT

  5.1.1. Assessment of the overall impact of COVID-19 on the industry
  5.1.2. Pre COVID-19 and post COVID-19 Market scenario

CHAPTER 6. GLOBAL DIFFICULT-TO-EXPRESS PROTEINS MARKET, BY PROTEIN

6.1. Market Snapshot
6.2. Global Difficult-to-Express Proteins Market by Protein, Performance - Potential Analysis
6.3. Global Difficult-to-Express Proteins Market Estimates & Forecasts by Protein 2018-2028 (USD Million)
6.4. Difficult-to-Express Proteins Market, Sub Segment Analysis
  6.4.1. Proteases
  6.4.2. Kinases
  6.4.3. Membrane Proteins
  6.4.4. Others

CHAPTER 7. GLOBAL DIFFICULT-TO-EXPRESS PROTEINS MARKET, BY TECHNOLOGY

7.1. Market Snapshot
7.2. Global Difficult-to-Express Proteins Market by Technology, Performance - Potential Analysis
7.3. Global Difficult-to-Express Proteins Market Estimates & Forecasts by Technology 2018-2028 (USD Million)
7.4. Difficult-to-Express Proteins Market, Sub Segment Analysis
  7.4.1. Cell-free Protein Synthesis
  7.4.2. Prokaryotic Expression Systems
  7.4.3. SUMO Fusion System
  7.4.4. Gene Fusion Systems
  7.4.5. Others

CHAPTER 8. GLOBAL DIFFICULT-TO-EXPRESS PROTEINS MARKET, BY APPLICATION

8.1. Market Snapshot
8.2. Global Difficult-to-Express Proteins Market by Application, Performance - Potential Analysis
8.3. Global Difficult-to-Express Proteins Market Estimates & Forecasts by Application 2018-2028 (USD Million)
8.4. Difficult-to-Express Proteins Market, Sub Segment Analysis
  8.4.1. Drug Discovery
  8.4.2. Protein Purification
  8.4.3. Protein Therapeutics
  8.4.4. Disease Diagnostics and Monitoring
  8.4.5. Others

CHAPTER 9. GLOBAL DIFFICULT-TO-EXPRESS PROTEINS MARKET, REGIONAL ANALYSIS

9.1. Difficult-to-Express Proteins Market, Regional Market Snapshot
9.2. North America Difficult-to-Express Proteins Market
  9.2.1. U.S. Difficult-to-Express Proteins Market
    9.2.1.1. Protein estimates & forecasts, 2018-2028
    9.2.1.2. Technology estimates & forecasts, 2018-2028
    9.2.1.3. Application estimates & forecasts, 2018-2028
  9.2.2. Canada Difficult-to-Express Proteins Market
9.3. Europe Difficult-to-Express Proteins Market Snapshot
  9.3.1. U.K. Difficult-to-Express Proteins Market
  9.3.2. Germany Difficult-to-Express Proteins Market
  9.3.3. France Difficult-to-Express Proteins Market
  9.3.4. Spain Difficult-to-Express Proteins Market
  9.3.5. Italy Difficult-to-Express Proteins Market
  9.3.6. Rest of Europe Difficult-to-Express Proteins Market
9.4. Asia-Pacific Difficult-to-Express Proteins Market Snapshot
  9.4.1. China Difficult-to-Express Proteins Market
  9.4.2. India Difficult-to-Express Proteins Market
  9.4.3. Japan Difficult-to-Express Proteins Market
  9.4.4. Australia Difficult-to-Express Proteins Market
  9.4.5. South Korea Difficult-to-Express Proteins Market
  9.4.6. Rest of Asia Pacific Difficult-to-Express Proteins Market
9.5. Latin America Difficult-to-Express Proteins Market Snapshot
  9.5.1. Brazil Difficult-to-Express Proteins Market
  9.5.2. Mexico Difficult-to-Express Proteins Market
9.6. Rest of The World Difficult-to-Express Proteins Market

CHAPTER 10. COMPETITIVE INTELLIGENCE

10.1. Top Market Strategies
10.2. Company Profiles
  10.2.1. R&D Systems
    10.2.1.1. Key Information
    10.2.1.2. Overview
    10.2.1.3. Financial (Subject to Data Availability)
    10.2.1.4. Product Summary
    10.2.1.5. Recent Developments
  10.2.2. Enzo Life Sciences
  10.2.3. Sino Biological
  10.2.4. Thermo Fisher Scientific
  10.2.5. StressMarq Biosciences
  10.2.6. LifeSensors Inc.
  10.2.7. Lucigen
  10.2.8. Batavia Biosciences Inc.
  10.2.9. WuXi Biologics
  10.2.10. Selexis SA

CHAPTER 11. RESEARCH PROCESS

11.1. Research Process
  11.1.1. Data Mining
  11.1.2. Analysis
  11.1.3. Market Estimation
  11.1.4. Validation
  11.1.5. Publishing
11.2. Research Attributes
11.3. Research Assumption

LIST OF TABLES

TABLE 1. Global Difficult-to-Express Proteins Market, report scope
TABLE 2. Global Difficult-to-Express Proteins Market estimates & forecasts by Region 2018-2028 (USD Million)
TABLE 3. Global Difficult-to-Express Proteins Market estimates & forecasts by Protein 2018-2028 (USD Million)
TABLE 4. Global Difficult-to-Express Proteins Market estimates & forecasts by Technology 2018-2028 (USD Million)
TABLE 5. Global Difficult-to-Express Proteins Market estimates & forecasts by Application 2018-2028 (USD Million)
TABLE 6. Global Difficult-to-Express Proteins Market by segment, estimates & forecasts, 2018-2028 (USD Million)
TABLE 7. Global Difficult-to-Express Proteins Market by region, estimates & forecasts, 2018-2028 (USD Million)
TABLE 8. Global Difficult-to-Express Proteins Market by segment, estimates & forecasts, 2018-2028 (USD Million)
TABLE 9. Global Difficult-to-Express Proteins Market by region, estimates & forecasts, 2018-2028 (USD Million)
TABLE 10. Global Difficult-to-Express Proteins Market by segment, estimates & forecasts, 2018-2028 (USD Million)
TABLE 11. Global Difficult-to-Express Proteins Market by region, estimates & forecasts, 2018-2028 (USD Million)
TABLE 12. Global Difficult-to-Express Proteins Market by segment, estimates & forecasts, 2018-2028 (USD Million)
TABLE 13. Global Difficult-to-Express Proteins Market by region, estimates & forecasts, 2018-2028 (USD Million)
TABLE 14. Global Difficult-to-Express Proteins Market by segment, estimates & forecasts, 2018-2028 (USD Million)
TABLE 15. Global Difficult-to-Express Proteins Market by region, estimates & forecasts, 2018-2028 (USD Million)
TABLE 16. U.S. Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)
TABLE 17. U.S. Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 18. U.S. Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 19. Canada Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)
TABLE 20. Canada Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 21. Canada Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 22. UK Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)
TABLE 23. UK Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 24. UK Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 25. Germany Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)
TABLE 26. Germany Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 27. Germany Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 28. RoE Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)
TABLE 29. RoE Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 30. RoE Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 31. China Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)
TABLE 32. China Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 33. China Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 34. India Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)
TABLE 35. India Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 36. India Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 37. Japan Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)
TABLE 38. Japan Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 39. Japan Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 40. RoAPAC Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)
TABLE 41. RoAPAC Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 42. RoAPAC Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 43. Brazil Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)
TABLE 44. Brazil Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 45. Brazil Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 46. Mexico Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)
TABLE 47. Mexico Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 48. Mexico Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 49. RoLA Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)
TABLE 50. RoLA Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 51. RoLA Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 52. Row Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)
TABLE 53. Row Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 54. Row Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)
TABLE 55. List of secondary sources, used in the study of global Difficult-to-Express Proteins Market
TABLE 56. List of primary sources, used in the study of global Difficult-to-Express Proteins Market
TABLE 57. Years considered for the study
TABLE 58. Exchange rates considered

LIST OF FIGURES

FIG 1. Global Difficult-to-Express Proteins Market, research methodology
FIG 2. Global Difficult-to-Express Proteins Market, Market estimation techniques
FIG 3. Global Market size estimates & forecast methods
FIG 4. Global Difficult-to-Express Proteins Market, key trends 2021
FIG 5. Global Difficult-to-Express Proteins Market, growth prospects 2022-2028
FIG 6. Global Difficult-to-Express Proteins Market, porters 5 force model
FIG 7. Global Difficult-to-Express Proteins Market, pest analysis
FIG 8. Global Difficult-to-Express Proteins Market, value chain analysis
FIG 9. Global Difficult-to-Express Proteins Market by segment, 2018 & 2028 (USD Million)
FIG 10. Global Difficult-to-Express Proteins Market by segment, 2018 & 2028 (USD Million)
FIG 11. Global Difficult-to-Express Proteins Market by segment, 2018 & 2028 (USD Million)
FIG 12. Global Difficult-to-Express Proteins Market by segment, 2018 & 2028 (USD Million)
FIG 13. Global Difficult-to-Express Proteins Market by segment, 2018 & 2028 (USD Million)
FIG 14. Global Difficult-to-Express Proteins Market, regional snapshot 2018 & 2028
FIG 15. North America Difficult-to-Express Proteins Market 2018 & 2028 (USD Million)
FIG 16. Europe Difficult-to-Express Proteins Market 2018 & 2028 (USD Million)
FIG 17. Asia pacific Market 2018 & 2028 (USD Million)
FIG 18. Latin America Difficult-to-Express Proteins Market 2018 & 2028 (USD Million)
FIG 19. Global Difficult-to-Express Proteins Market, company Market share analysis (2021)



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