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Gene Editing Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Product & Service (Reagents & consumables, Systems, Software), By Technology (CRISPER, TALEN, ZFN, Antisense), By Application (Cell Line Engineering, Genetic Engineering, Drug discovery), By End User (Pharma, Biotech, CROs), By Region and Competition, 2019-2029F

June 2024 | 180 pages | ID: GB4D867026B7EN
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Global Gene Editing Market was valued at USD 5.79 Billion in 2023 and is anticipated t%li%project steady growth in the forecast period with a CAGR of 8.98% through 2029. The Global Gene Editing Market has emerged as a dynamic and rapidly evolving landscape at the intersection of biotechnology and healthcare. Gene editing technologies, such as CRISPR-Cas9, TALEN, and zinc finger nucleases, have revolutionized the way scientists manipulate and modify genetic material, opening up unprecedented possibilities for therapeutic applications, agricultural improvements, and industrial advancements. The market's growth is propelled by a surge in research and development activities, increasing demand for personalized medicine, and a growing focus on genetic diseases. In the healthcare sector, gene editing holds immense potential for treating genetic disorders by precisely altering the DNA code responsible for disease manifestation. The market has witnessed a proliferation of biotechnology companies and research institutions engaged in developing and commercializing gene editing tools and therapies.

The demand for gene editing technologies is not limited t%li%the healthcare sector, extending t%li%agriculture and industrial applications. In agriculture, gene editing enables the development of crops with improved yields, resistance t%li%pests and diseases, and enhanced nutritional profiles. This has significant implications for addressing global food security challenges. In the industrial realm, gene editing is harnessed for the production of bio-based materials, enzymes, and pharmaceuticals, driving innovation and sustainability. The regulatory landscape is a critical factor shaping the trajectory of the global gene editing market, with ongoing discussions on ethical considerations, safety concerns, and the responsible use of these powerful tools.

Key Market Drivers

Rapid Technological Advancements

Rapid technological advancements have emerged as a catalyst for transformative changes in various industries, and the field of gene editing is n%li%exception. The Global Gene Editing Market is experiencing a substantial boost due t%li%breakthroughs in technology that have revolutionized the way genetic information is manipulated. One of the key drivers of this surge is the advent of CRISPR-Cas9, a revolutionary gene-editing tool that has made precise and targeted genetic modifications more accessible than ever before. This technology has significantly reduced the cost and time required for genetic editing, democratizing access t%li%gene-editing capabilities across research institutions, pharmaceutical companies, and biotech startups.

The integration of machine learning and artificial intelligence (AI) int%li%gene editing processes has further propelled the market forward. These technologies enhance the efficiency and accuracy of gene editing by analyzing vast datasets t%li%identify potential targets and predict the outcomes of genetic modifications. The synergy between AI and gene editing has not only accelerated the research and development processes but has als%li%opened new avenues for therapeutic applications. With AI-driven algorithms, researchers can design more effective and precise interventions for a wide range of genetic disorders, paving the way for personalized medicine.

The development of advanced delivery systems for gene-editing tools has expanded the possibilities of their application. Nanotechnology has played a pivotal role in creating efficient and targeted delivery mechanisms, minimizing off-target effects and increasing the overall safety of gene-editing procedures. These advancements have broadened the scope of gene editing beyond traditional applications, such as the treatment of genetic diseases, t%li%include areas like agriculture, where genes can be modified t%li%enhance crop yield, nutritional content, and resistance t%li%diseases. As a result of these rapid technological advancements, the global gene editing market has witnessed a surge in investment and collaboration. Pharmaceutical companies are increasingly partnering with technology firms and research institutions t%li%harness the full potential of gene editing in drug discovery and development.

Rising Industrial Applications and Biomanufacturing

The Global Gene Editing Market is experiencing a significant upswing propelled by the burgeoning industrial applications and the advent of biomanufacturing processes. As gene editing technologies mature, industries ranging from agriculture t%li%biopharmaceuticals are harnessing their power t%li%optimize production processes and create innovative solutions. In agriculture, gene editing is being utilized t%li%engineer crops with enhanced traits such as improved yields, resistance t%li%pests, and increased nutritional content. This not only addresses global food security challenges but als%li%contributes t%li%sustainable agriculture practices by reducing the reliance on chemical inputs.

Biomanufacturing, a key driver of the gene editing market, is witnessing a transformative shift with the integration of gene editing technologies. The ability t%li%precisely modify the genetic makeup of microorganisms used in industrial processes has led t%li%the development of more efficient and tailored production strains. This has immense implications for the pharmaceutical and biofuel industries, where the optimization of microbial or cell-based production systems is crucial. Gene editing enables the engineering of cell lines t%li%produce therapeutic proteins with enhanced efficacy, paving the way for the development of advanced biologics and gene therapies.

The scalability and reproducibility of gene-edited cell lines in biomanufacturing processes have als%li%streamlined the production of vaccines and other biopharmaceuticals. This not only expedites the manufacturing timeline but als%li%ensures a higher level of consistency and quality in the final products. The ability t%li%rapidly generate cell lines with desirable traits has become a game-changer in the biopharmaceutical sector, accelerating drug development and reducing production costs. The rise of synthetic biology, coupled with gene editing tools, has unlocked novel possibilities in industrial biotechnology. Companies are leveraging these technologies t%li%design microorganisms that can produce bio-based chemicals, materials, and fuels, thereby contributing t%li%a more sustainable and eco-friendly industrial landscape.

Key Market Challenges

Off-Target Effects and Precision Concerns

The promise of precision in gene editing technologies, exemplified by tools like CRISPR-Cas9, has revolutionized genetic research and therapeutic interventions. However, a significant challenge looms over the Global Gene Editing Market: off-target effects and precision concerns. Despite the remarkable specificity these tools offer, the risk of unintended modifications at locations in the genome resembling the target site poses a substantial hurdle.

Off-target effects are inherent in the gene editing process, raising concerns about the safety and reliability of applications across various sectors, particularly in therapeutic contexts. The potential for unintended changes t%li%the genetic code could lead t%li%unpredictable consequences, impacting the efficacy and safety of gene editing interventions. Researchers and biotech companies are intensively focused on developing strategies t%li%enhance the precision of gene editing tools, employing advanced algorithms, modified Cas proteins, and alternative delivery methods t%li%minimize off-target effects.

In therapeutic applications, precision is paramount. The challenge lies in ensuring that gene editing occurs only at the intended site, avoiding inadvertent alterations t%li%non-target regions of the genome. Ongoing research aims t%li%refine and optimize these tools t%li%strike a delicate balance between achieving the desired modifications and minimizing the risk of unintended genetic changes.

The pursuit of solutions t%li%off-target effects involves a multifaceted approach, incorporating advancements in bioinformatics, improved target site selection algorithms, and the development of novel delivery systems. As the gene editing community works tirelessly t%li%address precision concerns, collaborations and knowledge-sharing are vital for accelerating progress and ensuring that emerging technologies meet the stringent standards required for therapeutic applications.

Regulatory Uncertainty and Frameworks

As the Global Gene Editing Market advances at an unprecedented pace, regulatory uncertainty and the absence of comprehensive frameworks present significant obstacles. The rapid evolution of gene editing technologies, exemplified by CRISPR-Cas9, has outpaced the development of clear and standardized regulations in many jurisdictions. This regulatory lag not only hinders the timely translation of innovative research int%li%practical applications but als%li%raises concerns about the ethical and responsible use of these powerful tools.

One of the critical challenges is the lack of a unified global regulatory framework for gene editing. Different countries and regions adopt varying approaches t%li%assess and regulate gene editing technologies, leading t%li%a fragmented landscape that complicates research, development, and commercialization efforts. The absence of harmonized international standards poses challenges for researchers, biotech companies, and clinicians seeking t%li%navigate a complex and evolving regulatory environment.

The uncertainty surrounding gene editing regulations extends t%li%ethical considerations, especially in areas such as germline editing and human gene therapy. Balancing scientific progress with ethical concerns is a delicate task, and the absence of clear regulatory guidance exacerbates the challenge. Stakeholders in the gene editing ecosystem, including researchers, policymakers, and industry players, stress the need for regulatory frameworks that strike a harmonious balance between promoting innovation and ensuring responsible research and applications.

Key Market Trends

Advancements in CRISPR-Cas9 Technology

Advancements in CRISPR-Cas9 technology are proving t%li%be a driving force behind the remarkable growth of the Global Gene Editing Market. CRISPR-Cas9, a revolutionary genome editing tool, has undergone continuous refinement and enhancement, pushing the boundaries of precision and versatility in genetic engineering. Researchers and biotech companies are actively engaged in improving CRISPR-Cas9's efficiency, specificity, and delivery mechanisms, catapulting it t%li%the forefront of gene editing technologies.

Recent breakthroughs include the development of novel Cas proteins such as Cas12 and Cas13, expanding the toolkit for precise genomic modifications. These advancements not only bolster the accuracy of gene editing but als%li%extend its applications across various sectors. In healthcare, CRISPR-Cas9 is enabling the development of targeted therapies for genetic disorders, with ongoing clinical trials showcasing its potential t%li%revolutionize treatment approaches. In agriculture, the enhanced precision of CRISPR-Cas9 is driving the development of crops with improved traits, addressing challenges in food security and sustainability. The industrial sector is als%li%witnessing the transformative impact of CRISPR-Cas9, with applications in biomanufacturing and the production of bio-based materials.

The integration of CRISPR-Cas9 with artificial intelligence is further accelerating the design and optimization of gene editing tools, ushering in a new era of efficiency and innovation. The advancements in CRISPR-Cas9 technology underscore its pivotal role in shaping the gene editing landscape, propelling the market forward and unlocking unprecedented possibilities for tailored genetic modifications across diverse fields. As research continues t%li%push the boundaries of what is achievable with CRISPR-Cas9, its evolving capabilities are poised t%li%redefine the future of medicine, agriculture, and industry, solidifying its status as a transformative technology with far-reaching implications for the global gene editing market.

Segmental Insights

Product & Service Insights

Based on Product & Service, Reagents & consumables have emerged as the dominant segment in the Global Gene Editing Market in 2023. Gene editing experiments are intricate and require a range of specialized reagents and consumables for processes like DNA extraction, purification, and sequencing. Researchers heavily depend on these products t%li%perform precise and efficient genetic modifications. The demand for reagents and consumables is particularly pronounced in academic research institutions, biotechnology companies, and pharmaceutical firms engaged in gene editing studies. The continuous evolution and optimization of gene editing technologies, such as CRISPR-Cas9, necessitate a consistent supply of high-quality reagents and consumables. As gene editing techniques become more sophisticated, researchers demand specific and reliable products t%li%ensure the accuracy and reproducibility of their experiments. This trend contributes t%li%the sustained growth in the market for reagents and consumables.

Technology Insights

Based on Technology, CRISPR have emerged as the fastest growing segment in the Global Gene Editing Market in 2023. CRISPR technology provides unparalleled precision and efficiency in gene editing compared t%li%previous methods. Its capability t%li%target specific DNA sequences and make exact modifications has transformed gene editing. CRISPR's relative ease of use and cost-effectiveness make it accessible t%li%a wider range of researchers and laboratories. In agriculture, CRISPR is employed t%li%develop crops with enhanced traits such as disease resistance, higher yields, and improved nutritional value, which is essential for addressing global food security challenges. Additionally, there is increasing acceptance of the ethical implications of using CRISPR for therapeutic purposes, particularly when it can prevent or treat serious genetic conditions.

Regional Insights

Based on Region, North America have emerged as the dominant region in the Global Gene Editing Market in 2023, holding the largest market share. North America hosts a robust biotechnology and pharmaceutical industry, including a multitude of companies specializing in gene editing technologies. These companies range from startups and emerging biotechs t%li%established pharmaceutical giants. The region's biotech hubs, such as the Boston-Cambridge area and the San Francisc%li%Bay Area, foster innovation and collaboration, creating an environment conducive t%li%the growth of the gene editing market. The United States, in particular, has been a pioneer in the development and application of gene editing technologies, with the revolutionary CRISPR-Cas9 system being a notable example. The continuous technological advancements and breakthroughs in gene editing tools and techniques contribute t%li%the region's dominance in the market. Researchers and companies in North America are often early adopters of cutting-edge gene editing technologies.

Key Market Players
  • CRISPR Therapeutics AG
  • Merck KGaA
    • Therm%li%Fisher Scientific, Inc.
  • GenScript Biotech Corporation
  • Agilent Technologies, Inc.
  • PerkinElmer Inc.
  • Lonza Group Ltd.
  • Tecan Trading AG
    • Sangam%li%Therapeutics, Inc.
  • Editas Medicine, Inc.
Report Scope:

In this report, the Global Gene Editing Market has been segmented int%li%the following categories, in addition t%li%the industry trends which have als%li%been detailed below:
  • Gene Editing Market, By Product & Service:
  • Reagents & Consumables
  • Systems
  • Software
  • Gene Editing Market, By Technology:
  • CRISPER
  • TALEN
  • ZFN
  • Antisense
  • Gene Editing Market, By Application:
  • Cell Line Engineering
  • Genetic Engineering
  • Drug discovery
  • Gene Editing Market, By End User:
  • Pharma
  • Biotech
  • CROs
  • Gene Editing Market, By Region:
  • North America
  • United States
  • Canada
  • Mexico
  • Europe
  • France
  • United Kingdom
  • Italy
  • Germany
  • Spain
  • Asia Pacific
  • China
  • India
  • Japan
  • Australia
  • South Korea
  • South America
  • Brazil
  • Argentina
  • Colombia
  • Middle East & Africa
  • South Africa
  • Saudi Arabia
  • UAE
Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the Global Gene Editing Market.

Available Customizations:

Global Gene Editing Market report with the given market data, TechSci Research offers customizations according t%li%a company's specific needs. The following customization options are available for the report:

Company Information
    • Detailed analysis and profiling of additional market players (up t%li%five).
1. PRODUCT OVERVIEW

1.1. Market Definition
1.2. Scope of the Market
  1.2.1. Markets Covered
  1.2.2. Years Considered for Study
  1.2.3. Key Market Segmentations

2. RESEARCH METHODOLOGY

2.1. Objective of the Study
2.2. Baseline Methodology
2.3. Key Industry Partners
2.4. Major Association and Secondary Sources
2.5. Forecasting Methodology
2.6. Data Triangulation & Validation
2.7. Assumptions and Limitations

3. EXECUTIVE SUMMARY

3.1. Overview of the Market
3.2. Overview of Key Market Segmentations
3.3. Overview of Key Market Players
3.4. Overview of Key Regions/Countries
3.5. Overview of Market Drivers, Challenges, Trends

4. GLOBAL GENE EDITING MARKET OUTLOOK

4.1. Market Size & Forecast
  4.1.1. By Value
4.2. Market Share & Forecast
  4.2.1. By Product & Service (Reagents& consumables, Systems, Software)
  4.2.2. By Technology (CRISPER, TALEN, ZFN, Antisense)
  4.2.3. By Application (Cell Line Engineering, Genetic Engineering, Drug discovery)
  4.2.4. By End User (Pharma, Biotech, CROs)
  4.2.5. By Region
  4.2.6. By Company (2023)
4.3. Market Map
  4.3.1. By Product & Service
  4.3.2. By Technology
  4.3.3. By Application
  4.3.4. By End User
  4.3.5. By Region

5. ASIA PACIFIC GENE EDITING MARKET OUTLOOK

5.1. Market Size & Forecast
  5.1.1. By Value
5.2. Market Share & Forecast
  5.2.1. By Product & Service
  5.2.2. By Technology
  5.2.3. By Application
  5.2.4. By End User
  5.2.5. By Country
5.3. Asia Pacific: Country Analysis
  5.3.1. China Gene Editing Market Outlook
    5.3.1.1. Market Size & Forecast
      5.3.1.1.1. By Value
    5.3.1.2. Market Share & Forecast
      5.3.1.2.1. By Product & Service
      5.3.1.2.2. By Technology
      5.3.1.2.3. By Application
      5.3.1.2.4. By End User
  5.3.2. India Gene Editing Market Outlook
    5.3.2.1. Market Size & Forecast
      5.3.2.1.1. By Value
    5.3.2.2. Market Share & Forecast
      5.3.2.2.1. By Product & Service
      5.3.2.2.2. By Technology
      5.3.2.2.3. By Application
      5.3.2.2.4. By End User
  5.3.3. Australia Gene Editing Market Outlook
    5.3.3.1. Market Size & Forecast
      5.3.3.1.1. By Value
    5.3.3.2. Market Share & Forecast
      5.3.3.2.1. By Product & Service
      5.3.3.2.2. By Technology
      5.3.3.2.3. By Application
      5.3.3.2.4. By End User
  5.3.4. Japan Gene Editing Market Outlook
    5.3.4.1. Market Size & Forecast
      5.3.4.1.1. By Value
    5.3.4.2. Market Share & Forecast
      5.3.4.2.1. By Product & Service
      5.3.4.2.2. By Technology
      5.3.4.2.3. By Application
      5.3.4.2.4. By End User
  5.3.5. South Korea Gene Editing Market Outlook
    5.3.5.1. Market Size & Forecast
      5.3.5.1.1. By Value
    5.3.5.2. Market Share & Forecast
      5.3.5.2.1. By Product & Service
      5.3.5.2.2. By Technology
      5.3.5.2.3. By Application
      5.3.5.2.4. By End User

6. EUROPE GENE EDITING MARKET OUTLOOK

6.1. Market Size & Forecast
  6.1.1. By Value
6.2. Market Share & Forecast
  6.2.1. By Product & Service
  6.2.2. By Technology
  6.2.3. By Application
  6.2.4. By End User
  6.2.5. By Country
6.3. Europe: Country Analysis
  6.3.1. France Gene Editing Market Outlook
    6.3.1.1. Market Size & Forecast
      6.3.1.1.1. By Value
    6.3.1.2. Market Share & Forecast
      6.3.1.2.1. By Product & Service
      6.3.1.2.2. By Technology
      6.3.1.2.3. By Application
      6.3.1.2.4. By End User
  6.3.2. Germany Gene Editing Market Outlook
    6.3.2.1. Market Size & Forecast
      6.3.2.1.1. By Value
    6.3.2.2. Market Share & Forecast
      6.3.2.2.1. By Product & Service
      6.3.2.2.2. By Technology
      6.3.2.2.3. By Application
      6.3.2.2.4. By End User
  6.3.3. Spain Gene Editing Market Outlook
    6.3.3.1. Market Size & Forecast
      6.3.3.1.1. By Value
    6.3.3.2. Market Share & Forecast
      6.3.3.2.1. By Product & Service
      6.3.3.2.2. By Technology
      6.3.3.2.3. By Application
      6.3.3.2.4. By End User
  6.3.4. Italy Gene Editing Market Outlook
    6.3.4.1. Market Size & Forecast
      6.3.4.1.1. By Value
    6.3.4.2. Market Share & Forecast
      6.3.4.2.1. By Product & Service
      6.3.4.2.2. By Technology
      6.3.4.2.3. By Application
      6.3.4.2.4. By End User
  6.3.5. United Kingdom Gene Editing Market Outlook
    6.3.5.1. Market Size & Forecast
      6.3.5.1.1. By Value
    6.3.5.2. Market Share & Forecast
      6.3.5.2.1. By Product & Service
      6.3.5.2.2. By Technology
      6.3.5.2.3. By Application
      6.3.5.2.4. By End User

7. NORTH AMERICA GENE EDITING MARKET OUTLOOK

7.1. Market Size & Forecast
  7.1.1. By Value
7.2. Market Share & Forecast
  7.2.1. By Product & Service
  7.2.2. By Technology
  7.2.3. By Application
  7.2.4. By End User
  7.2.5. By Country
7.3. North America: Country Analysis
  7.3.1. United States Gene Editing Market Outlook
    7.3.1.1. Market Size & Forecast
      7.3.1.1.1. By Value
    7.3.1.2. Market Share & Forecast
      7.3.1.2.1. By Product & Service
      7.3.1.2.2. By Technology
      7.3.1.2.3. By Application
      7.3.1.2.4. By End User
  7.3.2. Mexico Gene Editing Market Outlook
    7.3.2.1. Market Size & Forecast
      7.3.2.1.1. By Value
    7.3.2.2. Market Share & Forecast
      7.3.2.2.1. By Product & Service
      7.3.2.2.2. By Technology
      7.3.2.2.3. By Application
      7.3.2.2.4. By End User
  7.3.3. Canada Gene Editing Market Outlook
    7.3.3.1. Market Size & Forecast
      7.3.3.1.1. By Value
    7.3.3.2. Market Share & Forecast
      7.3.3.2.1. By Product & Service
      7.3.3.2.2. By Technology
      7.3.3.2.3. By Application
      7.3.3.2.4. By End User

8. SOUTH AMERICA GENE EDITING MARKET OUTLOOK

8.1. Market Size & Forecast
  8.1.1. By Value
8.2. Market Share & Forecast
  8.2.1. By Product & Service
  8.2.2. By Technology
  8.2.3. By Application
  8.2.4. By End User
  8.2.5. By Country
8.3. South America: Country Analysis
  8.3.1. Brazil Gene Editing Market Outlook
    8.3.1.1. Market Size & Forecast
      8.3.1.1.1. By Value
    8.3.1.2. Market Share & Forecast
      8.3.1.2.1. By Product & Service
      8.3.1.2.2. By Technology
      8.3.1.2.3. By Application
      8.3.1.2.4. By End User
  8.3.2. Argentina Gene Editing Market Outlook
    8.3.2.1. Market Size & Forecast
      8.3.2.1.1. By Value
    8.3.2.2. Market Share & Forecast
      8.3.2.2.1. By Product & Service
      8.3.2.2.2. By Technology
      8.3.2.2.3. By Application
      8.3.2.2.4. By End User
  8.3.3. Colombia Gene Editing Market Outlook
    8.3.3.1. Market Size & Forecast
      8.3.3.1.1. By Value
    8.3.3.2. Market Share & Forecast
      8.3.3.2.1. By Product & Service
      8.3.3.2.2. By Technology
      8.3.3.2.3. By Application
      8.3.3.2.4. By End User

9. MIDDLE EAST AND AFRICA GENE EDITING MARKET OUTLOOK

9.1. Market Size & Forecast
  9.1.1. By Value
9.2. Market Share & Forecast
  9.2.1. By Product & Service
  9.2.2. By Technology
  9.2.3. By Application
  9.2.4. By End User
  9.2.5. By Country
9.3. MEA: Country Analysis
  9.3.1. South Africa Gene Editing Market Outlook
    9.3.1.1. Market Size & Forecast
      9.3.1.1.1. By Value
    9.3.1.2. Market Share & Forecast
      9.3.1.2.1. By Product & Service
      9.3.1.2.2. By Technology
      9.3.1.2.3. By Application
      9.3.1.2.4. By End User
  9.3.2. Saudi Arabia Gene Editing Market Outlook
    9.3.2.1. Market Size & Forecast
      9.3.2.1.1. By Value
    9.3.2.2. Market Share & Forecast
      9.3.2.2.1. By Product & Service
      9.3.2.2.2. By Technology
      9.3.2.2.3. By Application
      9.3.2.2.4. By End User
  9.3.3. UAE Gene Editing Market Outlook
    9.3.3.1. Market Size & Forecast
      9.3.3.1.1. By Value
    9.3.3.2. Market Share & Forecast
      9.3.3.2.1. By Product & Service
      9.3.3.2.2. By Technology
      9.3.3.2.3. By Application
      9.3.3.2.4. By End User

10. MARKET DYNAMICS

10.1. Drivers
10.2. Challenges

11. MARKET TRENDS & DEVELOPMENTS

11.1. Recent Developments
11.2. Product Launches
11.3. Mergers & Acquisitions

12. GLOBAL GENE EDITING MARKET: SWOT ANALYSIS

13. PORTER’S FIVE FORCES ANALYSIS

13.1. Competition in the Industry
13.2. Potential of New Entrants
13.3. Power of Suppliers
13.4. Power of Customers
13.5. Threat of Substitute Product

14. COMPETITIVE LANDSCAPE

14.1. CRISPR Therapeutics AG
  14.1.1. Business Overview
  14.1.2. Company Snapshot
  14.1.3. Products & Services
  14.1.4. Financials (In case of listed)
  14.1.5. Recent Developments
  14.1.6. SWOT Analysis
14.2. Merck KGaA
14.3. Thermo Fisher Scientific, Inc.
14.4. GenScript Biotech Corporation
14.5. Agilent Technologies, Inc.
14.6. PerkinElmer Inc.
14.7. Lonza Group Ltd.
14.8. Tecan Trading AG
14.9. Sangamo Therapeutics, Inc.
14.10. Editas Medicine, Inc.

15. STRATEGIC RECOMMENDATIONS

16. ABOUT US & DISCLAIMER


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