Epiomic Epidemiology Series: Frontotemporal Lobe Dementia Forecast in 9 Major Markets 2015-2025

November 2015 | 38 pages | ID: E77050295A0EN
Black Swan Analysis limited

Abstracts

Frontotemporal lobe dementia (FTD) is a progressive degenerative disorder characterised by degeneration and atrophy of the frontal and anterior temporal lobes. It is the second most common neurodegenerative disorder resulting in dementia in the under 65's and a limited life expectancy. This report provides the current prevalent population for FTD across 9 Major Markets (USA, France, Germany, Italy, Spain, UK, Brazil, Japan and India) split by gender and 5-year age cohort. Along with the current prevalence, the report provides a breakdown of the sub-group classifications of the disease, disease origin and tau protein mutations in the FTD patient population. The report also contains a disease overview of the risk factors, disease diagnosis and prognosis along with specific variations by geography and ethnicity.

Providing a value-added level of insight from the analysis team at Black Swan, several of the main symptoms and co-morbidities of FTD have been quantified and presented alongside the overall prevalence figures. These sub-populations within the main disease are also included at a country level across the 10-year forecast snapshot.

Main symptoms and co-morbidities for FTD include:

• Dementia and cognitive disorders
• Speech and semantic problems
• Limb/muscle weakness and rigidity
• Behavioural disorders
• Appetite changes

This report is built using data and information sourced from the proprietary Epiomic patient segmentation database. To generate accurate patient population estimates, the Epiomic database utilises a combination of several world class sources that deliver the most up to date information form patient registries, clinical trials and epidemiology studies. All of the sources used to generate the data and analysis have been identified in the report.

Reason to buy

• Able to quantify patient populations in global FTD’s market to target the development of future products, pricing strategies and launch plans.
• Gain further insight into the prevalence of the subdivided types of FTD and identify patient segments with high potential.
• Delivery of more accurate information for clinical trials in study sizing and realistic patient recruitment for various countries.
• Provide a level of understanding on the impact from specific co-morbid conditions on FTD’s prevalent population.
• Examination of the prevalence for different causative protein mutations in FTD.
• Identify sub-populations within FTD which require treatment.
• Gain an understanding of the specific markets that have the largest number of FTD patients.

Contents

Introduction
Cause of the Disease
Risk Factors & Prevention
Diagnosis of the Disease
Variation by Geography/Ethnicity
Disease Prognosis & Clinical Course
Key Co-morbid Conditions /Features Associated with the Disease
Methodology for Quantification of Patient Numbers
Top-Line Prevalence for Frontotemporal Lobe Dementia
Main Features of Frontotemporal Lobe Dementia
  FTD Clinical Syndrome Classification
  Type of FTD by Protein Mutation
  Neurological Diseases Associated with FTD Patients
  Behavioural Disorders in FTD Patients
Abbreviations used in the Report
Other Black Swan Analysis Publications
Black Swan Analysis Online Patient-Based Databases
Patient-Based Offering
Online Pricing Data and Platforms
References
Appendix

List Of Tables

LIST OF TABLES

Prevalence of FTD, total (000s)
Prevalence of FTD, males (000s)
Prevalence of FTD, females (000s)
Sub-group classification of FTD, total (000s)
Origin of FTD in patients, total (000s)
Tau mutation type in FTD patients, total (000s)
Alzheimer’s disease in FTD patients, total (000s)
ALS in FTD patients, total (000s)
Disinhibition in FTD patients, total (000s)
Agitation in FTD patients, total (000s)
Anxiety in FTD patients, total (000s)
Apathy in FTD patients, total (000s)
Abbreviations and acronyms used in the report
USA Prevalence of FTD by 5-yr age cohort, males (000s)
USA Prevalence of FTD by 5-yr age cohort, females (000s)
France Prevalence of FTD by 5-yr age cohort, males (000s)
France Prevalence of FTD by 5-yr age cohort, females (000s)
Germany Prevalence of FTD by 5-yr age cohort, males (000s)
Germany Prevalence of FTD by 5-yr age cohort, females (000s)
Italy Prevalence of FTD by 5-yr age cohort, males (000s)
Italy Prevalence of FTD by 5-yr age cohort, females (000s)
Spain Prevalence of FTD by 5-yr age cohort, males (000s)
Spain Prevalence of FTD by 5-yr age cohort, females (000s)
United Kingdom Prevalence of FTD by 5-yr age cohort, males (000s)
United Kingdom Prevalence of FTD by 5-yr age cohort, females (000s)
Brazil Prevalence of FTD by 5-yr age cohort, males (000s)
Brazil Prevalence of FTD by 5-yr age cohort, females (000s)
Japan Prevalence of FTD by 5-yr age cohort, males (000s)
Japan Prevalence of FTD by 5-yr age cohort, females (000s)
India Prevalence of FTD by 5-yr age cohort, males (000s)
India Prevalence of FTD by 5-yr age cohort, females (000s)