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Cluster Headache Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

May 2024 | 131 pages | ID: C8E215F1E21CEN
IMARC Group

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The 7 major cluster headache markets reached a value of US$ 812.8 Million in 2023. Looking forward, IMARC Group expects the 7MM to reach US$ 1,124.6 Million by 2034, exhibiting a growth rate (CAGR) of 3% during 2024-2034.

The cluster headache market has been comprehensively analyzed in IMARC's new report titled "Cluster Headache Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034".Cluster headache refers to a neurological condition characterized by intensely painful headache attacks. They often strike suddenly and recur cyclically in periods or clusters for weeks or months before remission. The pain, typically focused around one eye, can be piercing, sharp, or burning and is generally severe enough to disrupt daily activities. Individuals suffering from the illness may also experience a drooping eyelid, tearing, nasal congestion, and restlessness. The diagnosis of cluster headache typically relies on the pattern of the symptoms and a detailed medical history. Neuroimaging tests, such as magnetic resonance imaging or computed tomography scans, may be performed to rule out several potential causes of the symptoms. It's crucial to differentiate this ailment from other types of conditions, like migraines or tension headaches, due to the different treatment strategies. A timely and accurate diagnosis is paramount, as cluster headache, though not life-threatening, can significantly affect a patient's quality of life.

The rising prevalence of neurological disorders that can lead to activation of the trigeminal nerve along with the release of neuropeptides, thereby stimulating electrical activity in the brain, is primarily driving the cluster headache market. In addition to this, the inflating utilization of effective medications, such as triptans and calcitonin gene-related peptide receptor antagonists, in managing acute cluster attacks and preventing their recurrence is also creating a positive outlook for the market. Moreover, the widespread adoption of neuromodulation devices, including occipital nerve stimulators and transcranial magnetic stimulation, owing to their numerous benefits, like non-invasiveness, reducing symptoms, enhancing the quality of life for individuals suffering from the ailment, etc., is further bolstering the market growth. These techniques aim to minimize the frequency and severity of the headaches by manipulating the nerve signals. Apart from this, the increasing understanding of the underlying pathophysiology, which has prompted various researchers and pharmaceutical companies to focus on developing novel therapies to address these specific mechanisms, is acting as another significant growth-inducing factor. Additionally, the emerging popularity of innovative treatments, such as monoclonal antibodies, since they target the calcitonin gene-related peptide implicated in causing the disease, is expected to drive the cluster headache market during the forecast period.

IMARC Group's new report provides an exhaustive analysis of the cluster headache market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for cluster headache and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the cluster headache market in any manner.

Time Period of the Study

Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034

Countries Covered

United States
Germany
France
United Kingdom
Italy
Spain
Japan

Analysis Covered Across Each Country

Historical, current, and future epidemiology scenario
Historical, current, and future performance of the cluster headache market
Historical, current, and future performance of various therapeutic categories in the market
Sales of various drugs across the cluster headache market
Reimbursement scenario in the market
In-market and pipeline drugs
Competitive Landscape:
This report also provides a detailed analysis of the current cluster headache marketed drugs and late-stage pipeline drugs.

In-Market Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.

Key Questions Answered in this Report:
Market Insights

How has the cluster headache market performed so far and how will it perform in the coming years?
What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
What was the country-wise size of the cluster headache market across the seven major markets in 2023 and what will it look like in 2034?
What is the growth rate of the cluster headache market across the seven major markets and what will be the expected growth over the next ten years?
What are the key unmet needs in the market?

Epidemiology Insights

What is the number of prevalent cases (2018-2034) of cluster headache across the seven major markets?
What is the number of prevalent cases (2018-2034) of cluster headache by age across the seven major markets?
What is the number of prevalent cases (2018-2034) of cluster headache by gender across the seven major markets?
How many patients are diagnosed (2018-2034) with cluster headache across the seven major markets?
What is the size of the cluster headache patient pool (2018-2023) across the seven major markets?
What would be the forecasted patient pool (2024-2034) across the seven major markets?
What are the key factors driving the epidemiological trend of cluster headache?
What will be the growth rate of patients across the seven major markets?

Cluster Headache: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

What are the current marketed drugs and what are their market performance?
What are the key pipeline drugs and how are they expected to perform in the coming years?
How safe are the current marketed drugs and what are their efficacies?
How safe are the late-stage pipeline drugs and what are their efficacies?
What are the current treatment guidelines for cluster headache drugs across the seven major markets?
Who are the key companies in the market and what are their market shares?
What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the cluster headache market?
What are the key regulatory events related to the cluster headache market?
What is the structure of clinical trial landscape by status related to the cluster headache market?
What is the structure of clinical trial landscape by phase related to the cluster headache market?
What is the structure of clinical trial landscape by route of administration related to the cluster headache market?
1 PREFACE

2 SCOPE AND METHODOLOGY

2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
  2.3.1 Primary Sources
  2.3.2 Secondary Sources
2.4 Market Estimation
  2.4.1 Bottom-Up Approach
  2.4.2 Top-Down Approach
2.5 Forecasting Methodology

3 EXECUTIVE SUMMARY

4 CLUSTER HEADACHE - INTRODUCTION

4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence

5 CLUSTER HEADACHE - DISEASE OVERVIEW

5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment

6 PATIENT JOURNEY

7 CLUSTER HEADACHE - EPIDEMIOLOGY AND PATIENT POPULATION

7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
  7.2.1 Epidemiology Scenario (2018-2023)
  7.2.2 Epidemiology Forecast (2024-2034)
  7.2.3 Epidemiology by Age (?2018-2034?)
  7.2.4 Epidemiology by Gender (?2018-2034?)
  7.2.5 Diagnosed Cases (?2018-2034?)
  7.2.6 Patient Pool/Treated Cases (?2018-2034?)
7.3 Epidemiology Scenario - United States
  7.3.1 Epidemiology Scenario (2018-2023)
  7.3.2 Epidemiology Forecast (2024-2034)
  7.3.3 Epidemiology by Age (?2018-2034?)
  7.3.4 Epidemiology by Gender (?2018-2034?)
  7.3.5 Diagnosed Cases (?2018-2034?)
  7.3.6 Patient Pool/Treated Cases (?2018-2034?)
7.4 Epidemiology Scenario - Germany
  7.4.1 Epidemiology Scenario (2018-2023)
  7.4.2 Epidemiology Forecast (2024-2034)
  7.4.3 Epidemiology by Age (?2018-2034?)
  7.4.4 Epidemiology by Gender (?2018-2034?)
  7.4.5 Diagnosed Cases (?2018-2034?)
  7.4.6 Patient Pool/Treated Cases (?2018-2034?)
7.5 Epidemiology Scenario - France
  7.5.1 Epidemiology Scenario (2018-2023)
  7.5.2 Epidemiology Forecast (2024-2034)
  7.5.3 Epidemiology by Age (?2018-2034?)
  7.5.4 Epidemiology by Gender (?2018-2034?)
  7.5.5 Diagnosed Cases (?2018-2034?)
  7.5.6 Patient Pool/Treated Cases (?2018-2034?)
7.6 Epidemiology Scenario - United Kingdom
  7.6.1 Epidemiology Scenario (2018-2023)
  7.6.2 Epidemiology Forecast (2024-2034)
  7.6.3 Epidemiology by Age (?2018-2034?)
  7.6.4 Epidemiology by Gender (?2018-2034?)
  7.6.5 Diagnosed Cases (?2018-2034?)
  7.6.6 Patient Pool/Treated Cases (?2018-2034?)
7.7 Epidemiology Scenario - Italy
  7.7.1 Epidemiology Scenario (2018-2023)
  7.7.2 Epidemiology Forecast (2024-2034)
  7.7.3 Epidemiology by Age (?2018-2034?)
  7.7.4 Epidemiology by Gender (?2018-2034?)
  7.7.5 Diagnosed Cases (?2018-2034?)
  7.7.6 Patient Pool/Treated Cases (?2018-2034?)
7.8 Epidemiology Scenario - Spain
  7.8.1 Epidemiology Scenario (2018-2023)
  7.8.2 Epidemiology Forecast (2024-2034)
  7.8.3 Epidemiology by Age (?2018-2034?)
  7.8.4 Epidemiology by Gender (?2018-2034?)
  7.8.5 Diagnosed Cases (?2018-2034?)
  7.8.6 Patient Pool/Treated Cases (?2018-2034?)
7.9 Epidemiology Scenario - Japan
  7.9.1 Epidemiology Scenario (2018-2023)
  7.9.2 Epidemiology Forecast (2024-2034)
  7.9.3 Epidemiology by Age (?2018-2034?)
  7.9.4 Epidemiology by Gender (?2018-2034?)
  7.9.5 Diagnosed Cases (?2018-2034?)
  7.9.6 Patient Pool/Treated Cases (?2018-2034?)

8 CLUSTER HEADACHE - TREATMENT ALGORITHM, GUIDELINES, AND MEDICAL PRACTICES

8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm

9 CLUSTER HEADACHE - UNMET NEEDS

10 CLUSTER HEADACHE - KEY ENDPOINTS OF TREATMENT

11 CLUSTER HEADACHE - MARKETED PRODUCTS

11.1 List of Cluster Headache Marketed Drugs Across the Top 7 Markets
  11.1.1 Emgality (Galcanezumab) - Eli Lilly and Company
    11.1.1.1 Drug Overview
    11.1.1.2 Mechanism of Action
    11.1.1.3 Regulatory Status
    11.1.1.4 Clinical Trial Results
    11.1.1.5 Sales Across Major Markets
  11.1.2 Imitrex (Sumatriptan) - GlaxoSmithKline
    11.1.2.1 Drug Overview
    11.1.2.2 Mechanism of Action
    11.1.2.3 Regulatory Status
    11.1.2.4 Clinical Trial Results
    11.1.2.5 Sales Across Major Markets
Kindly note that the above only represents a partial list of marketed drugs, and the complete list has been provided in the report.

12 CLUSTER HEADACHE - PIPELINE DRUGS

12.1 List of Cluster Headache Pipeline Drugs Across the Top 7 Markets
  12.1.1 Eptinezumab - Lundbeck Seattle BioPharmaceuticals
    12.1.1.1 Drug Overview
    12.1.1.2 Mechanism of Action
    12.1.1.3 Clinical Trial Results
    12.1.1.4 Safety and Efficacy
    12.1.1.5 Regulatory Status
Kindly note that the above only represents a partial list of pipeline drugs, and the complete list has been provided in the report.

13. CLUSTER HEADACHE - ATTRIBUTE ANALYSIS OF KEY MARKETED AND PIPELINE DRUGS

14. CLUSTER HEADACHE – CLINICAL TRIAL LANDSCAPE

14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events

15 CLUSTER HEADACHE - MARKET SCENARIO

15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
  15.2.1 Cluster Headache - Market Size
    15.2.1.1 Market Size (2018-2023)
    15.2.1.2 Market Forecast (2024-2034)
  15.2.2 Cluster Headache - Market Size by Therapies
    15.2.2.1 Market Size by Therapies (2018-2023)
    15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
  15.3.1 Cluster Headache - Market Size
    15.3.1.1 Market Size (2018-2023)
    15.3.1.2 Market Forecast (2024-2034)
  15.3.2 Cluster Headache - Market Size by Therapies
    15.3.2.1 Market Size by Therapies (2018-2023)
    15.3.2.2 Market Forecast by Therapies (2024-2034)
  15.3.3 Cluster Headache - Access and Reimbursement Overview
15.4 Market Scenario - Germany
  15.4.1 Cluster Headache - Market Size
    15.4.1.1 Market Size (2018-2023)
    15.4.1.2 Market Forecast (2024-2034)
  15.4.2 Cluster Headache - Market Size by Therapies
    15.4.2.1 Market Size by Therapies (2018-2023)
    15.4.2.2 Market Forecast by Therapies (2024-2034)
  15.4.3 Cluster Headache - Access and Reimbursement Overview
15.5 Market Scenario - France
  15.5.1 Cluster Headache - Market Size
    15.5.1.1 Market Size (2018-2023)
    15.5.1.2 Market Forecast (2024-2034)
  15.5.2 Cluster Headache - Market Size by Therapies
    15.5.2.1 Market Size by Therapies (2018-2023)
    15.5.2.2 Market Forecast by Therapies (2024-2034)
  15.5.3 Cluster Headache - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
  15.6.1 Cluster Headache - Market Size
    15.6.1.1 Market Size (2018-2023)
    15.6.1.2 Market Forecast (2024-2034)
  15.6.2 Cluster Headache - Market Size by Therapies
    15.6.2.1 Market Size by Therapies (2018-2023)
    15.6.2.2 Market Forecast by Therapies (2024-2034)
  15.6.3 Cluster Headache - Access and Reimbursement Overview
15.7 Market Scenario - Italy
  15.7.1 Cluster Headache - Market Size
    15.7.1.1 Market Size (2018-2023)
    15.7.1.2 Market Forecast (2024-2034)
  15.7.2 Cluster Headache - Market Size by Therapies
    15.7.2.1 Market Size by Therapies (2018-2023)
    15.7.2.2 Market Forecast by Therapies (2024-2034)
  15.7.3 Cluster Headache - Access and Reimbursement Overview
15.8 Market Scenario - Spain
  15.8.1 Cluster Headache - Market Size
    15.8.1.1 Market Size (2018-2023)
    15.8.1.2 Market Forecast (2024-2034)
  15.8.2 Cluster Headache - Market Size by Therapies
    15.8.2.1 Market Size by Therapies (2018-2023)
    15.8.2.2 Market Forecast by Therapies (2024-2034)
  15.8.3 Cluster Headache - Access and Reimbursement Overview
15.9 Market Scenario - Japan
  15.9.1 Cluster Headache - Market Size
    15.9.1.1 Market Size (2018-2023)
    15.9.1.2 Market Forecast (2024-2034)
  15.9.2 Cluster Headache - Market Size by Therapies
    15.9.2.1 Market Size by Therapies (2018-2023)
    15.9.2.2 Market Forecast by Therapies (2024-2034)
  15.9.3 Cluster Headache - Access and Reimbursement Overview

16 CLUSTER HEADACHE - RECENT EVENTS AND INPUTS FROM KEY OPINION LEADERS

17 CLUSTER HEADACHE MARKET - SWOT ANALYSIS

17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats

18 CLUSTER HEADACHE MARKET – STRATEGIC RECOMMENDATIONS

19 APPENDIX


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