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Calciphylaxis Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

May 2024 | 134 pages | ID: C7C0A43657FCEN
IMARC Group

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The 7 major calciphylaxis markets reached a value of US$ 1.2 Billion in 2023. Looking forward, IMARC Group expects the 7MM to reach US$ 2.6 Billion by 2034, exhibiting a growth rate (CAGR) of 7.37% during 2024-2034.

The calciphylaxis market has been comprehensively analyzed in IMARC's new report titled "Calciphylaxis Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Calciphylaxis, also known as calcific uremic arteriolopathy, is a rare condition that can cause tissue death due to calcium buildup in the small blood vessels. It primarily affects people with end-stage renal disease or kidney disorders but can also occur in individuals with normal kidney function. The illness typically manifests as painful skin lesions or wounds, which can progress to necrosis or gangrene if left untreated. Various other symptoms of calciphylaxis may include fever, malaise, muscle or joint pain, etc. Diagnosing the ailment can be challenging, as the indications are non-specific and resemble other skin conditions. To diagnose the disorder, a physician will typically perform a physical examination and order laboratory tests to examine the levels of calcium, phosphate, and parathyroid hormone in the blood. Several imaging studies, such as Doppler ultrasound and computed tomography (CT) scans, are also used to evaluate the extent of the disease and assess blood flow to the affected areas. Additionally, a skin biopsy may be necessary to confirm the diagnosis by examining the tissue for evidence of calcification and tissue damage.

The increasing cases of abnormal calcium and phosphate metabolism, which can lead to the deposition of calcium in blood vessels, are primarily driving the calciphylaxis market. In addition to this, the rising incidence of several associated risk factors, such as hyperthyroidism, vitamin D deficiency, obesity, use of calcium-containing phosphate binders, etc., is also propelling the market growth. Furthermore, the inflating adoption of effective medications, including sodium thiosulfate, bisphosphonates, cinacalcet, etc., for reducing the levels of calcium in the blood and preventing the formation of blood clots is acting as another significant growth-inducing factor. Apart from this, the escalating application of hyperbaric oxygen therapy, which involves breathing oxygen in a pressurized chamber to improve blood flow to the affected areas and promote wound healing, is also creating a positive outlook for the market. Moreover, the emerging popularity of advanced wound care techniques, such as negative pressure wound therapy and advanced dressings, since they can stimulate the growth of healthy tissues and reduce the risk of infection in individuals with large or deep wounds, is expected to drive the calciphylaxis market in the coming years.

IMARC Group's new report provides an exhaustive analysis of the calciphylaxis market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for calciphylaxis and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the calciphylaxis market in any manner.

Time Period of the Study

Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034

Countries Covered

United States
Germany
France
United Kingdom
Italy
Spain
Japan

Analysis Covered Across Each Country

Historical, current, and future epidemiology scenario
Historical, current, and future performance of the calciphylaxis market
Historical, current, and future performance of various therapeutic categories in the market
Sales of various drugs across the calciphylaxis market
Reimbursement scenario in the market
In-market and pipeline drugs
Competitive Landscape:
This report also provides a detailed analysis of the current calciphylaxis marketed drugs and late-stage pipeline drugs.

In-Market Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.

Key Questions Answered in this Report:
Market Insights

How has the calciphylaxis market performed so far and how will it perform in the coming years?
What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
What was the country-wise size of the calciphylaxis market across the seven major markets in 2023 and what will it look like in 2034?
What is the growth rate of the calciphylaxis market across the seven major markets and what will be the expected growth over the next ten years?
What are the key unmet needs in the market?

Epidemiology Insights

What is the number of prevalent cases (2018-2034) of calciphylaxis across the seven major markets?
What is the number of prevalent cases (2018-2034) of calciphylaxis by age across the seven major markets?
What is the number of prevalent cases (2018-2034) of calciphylaxis by gender across the seven major markets?
How many patients are diagnosed (2018-2034) with calciphylaxis across the seven major markets?
What is the size of the calciphylaxis patient pool (2018-2023) across the seven major markets?
What would be the forecasted patient pool (2024-2034) across the seven major markets?
What are the key factors driving the epidemiological trend of calciphylaxis?
What will be the growth rate of patients across the seven major markets?

Calciphylaxis: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

What are the current marketed drugs and what are their market performance?
What are the key pipeline drugs and how are they expected to perform in the coming years?
How safe are the current marketed drugs and what are their efficacies?
How safe are the late-stage pipeline drugs and what are their efficacies?
What are the current treatment guidelines for calciphylaxis drugs across the seven major markets?
Who are the key companies in the market and what are their market shares?
What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the calciphylaxis market?
What are the key regulatory events related to the calciphylaxis market?
What is the structure of clinical trial landscape by status related to the calciphylaxis market?
What is the structure of clinical trial landscape by phase related to the calciphylaxis market?
What is the structure of clinical trial landscape by route of administration related to the calciphylaxis market?
1 PREFACE

2 SCOPE AND METHODOLOGY

2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
  2.3.1 Primary Sources
  2.3.2 Secondary Sources
2.4 Market Estimation
  2.4.1 Bottom-Up Approach
  2.4.2 Top-Down Approach
2.5 Forecasting Methodology

3 EXECUTIVE SUMMARY

4 CALCIPHYLAXIS - INTRODUCTION

4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence

5 CALCIPHYLAXIS - DISEASE OVERVIEW

5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment

6 PATIENT JOURNEY

7 CALCIPHYLAXIS - EPIDEMIOLOGY AND PATIENT POPULATION

7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
  7.2.1 Epidemiology Scenario (2018-2023)
  7.2.2 Epidemiology Forecast (2024-2034)
  7.2.3 Epidemiology by Age (?2018-2034?)
  7.2.4 Epidemiology by Gender (?2018-2034?)
  7.2.5 Diagnosed Cases (?2018-2034?)
  7.2.6 Patient Pool/Treated Cases (?2018-2034?)
7.3 Epidemiology Scenario - United States
  7.3.1 Epidemiology Scenario (2018-2023)
  7.3.2 Epidemiology Forecast (2024-2034)
  7.3.3 Epidemiology by Age (?2018-2034?)
  7.3.4 Epidemiology by Gender (?2018-2034?)
  7.3.5 Diagnosed Cases (?2018-2034?)
  7.3.6 Patient Pool/Treated Cases (?2018-2034?)
7.4 Epidemiology Scenario - Germany
  7.4.1 Epidemiology Scenario (2018-2023)
  7.4.2 Epidemiology Forecast (2024-2034)
  7.4.3 Epidemiology by Age (?2018-2034?)
  7.4.4 Epidemiology by Gender (?2018-2034?)
  7.4.5 Diagnosed Cases (?2018-2034?)
  7.4.6 Patient Pool/Treated Cases (?2018-2034?)
7.5 Epidemiology Scenario - France
  7.5.1 Epidemiology Scenario (2018-2023)
  7.5.2 Epidemiology Forecast (2024-2034)
  7.5.3 Epidemiology by Age (?2018-2034?)
  7.5.4 Epidemiology by Gender (?2018-2034?)
  7.5.5 Diagnosed Cases (?2018-2034?)
  7.5.6 Patient Pool/Treated Cases (?2018-2034?)
7.6 Epidemiology Scenario - United Kingdom
  7.6.1 Epidemiology Scenario (2018-2023)
  7.6.2 Epidemiology Forecast (2024-2034)
  7.6.3 Epidemiology by Age (?2018-2034?)
  7.6.4 Epidemiology by Gender (?2018-2034?)
  7.6.5 Diagnosed Cases (?2018-2034?)
  7.6.6 Patient Pool/Treated Cases (?2018-2034?)
7.7 Epidemiology Scenario - Italy
  7.7.1 Epidemiology Scenario (2018-2023)
  7.7.2 Epidemiology Forecast (2024-2034)
  7.7.3 Epidemiology by Age (?2018-2034?)
  7.7.4 Epidemiology by Gender (?2018-2034?)
  7.7.5 Diagnosed Cases (?2018-2034?)
  7.7.6 Patient Pool/Treated Cases (?2018-2034?)
7.8 Epidemiology Scenario - Spain
  7.8.1 Epidemiology Scenario (2018-2023)
  7.8.2 Epidemiology Forecast (2024-2034)
  7.8.3 Epidemiology by Age (?2018-2034?)
  7.8.4 Epidemiology by Gender (?2018-2034?)
  7.8.5 Diagnosed Cases (?2018-2034?)
  7.8.6 Patient Pool/Treated Cases (?2018-2034?)
7.9 Epidemiology Scenario - Japan
  7.9.1 Epidemiology Scenario (2018-2023)
  7.9.2 Epidemiology Forecast (2024-2034)
  7.9.3 Epidemiology by Age (?2018-2034?)
  7.9.4 Epidemiology by Gender (?2018-2034?)
  7.9.5 Diagnosed Cases (?2018-2034?)
  7.9.6 Patient Pool/Treated Cases (?2018-2034?)

8 CALCIPHYLAXIS - TREATMENT ALGORITHM, GUIDELINES, AND MEDICAL PRACTICES

8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm

9 CALCIPHYLAXIS - UNMET NEEDS

10 CALCIPHYLAXIS - KEY ENDPOINTS OF TREATMENT

11 CALCIPHYLAXIS - MARKETED PRODUCTS

11.1 List of Calciphylaxis Marketed Drugs Across the Top 7 Markets
  11.1.1 Drug Name – Company Name
    11.1.1.1 Drug Overview
    11.1.1.2 Mechanism of Action
    11.1.1.3 Regulatory Status
    11.1.1.4 Clinical Trial Results
    11.1.1.5 Sales Across Major Markets
Kindly note that the complete list of marketed drugs has been provided in the report.

12 CALCIPHYLAXIS - PIPELINE DRUGS

12.1 List of Calciphylaxis Pipeline Drugs Across the Top 7 Markets
  12.1.1 SNF472 - Sanifit
    12.1.1.1 Drug Overview
    12.1.1.2 Mechanism of Action
    12.1.1.3 Clinical Trial Results
    12.1.1.4 Safety and Efficacy
    12.1.1.5 Regulatory Status
  12.1.2 Sodium Thiosulfate - Hope Pharmaceuticals
    12.1.2.1 Drug Overview
    12.1.2.2 Mechanism of Action
    12.1.2.3 Clinical Trial Results
    12.1.2.4 Safety and Efficacy
    12.1.2.5 Regulatory Status
Kindly note that the above only represents a partial list of pipeline drugs, and the complete list has been provided in the report.

13. CALCIPHYLAXIS - ATTRIBUTE ANALYSIS OF KEY MARKETED AND PIPELINE DRUGS

14. CALCIPHYLAXIS – CLINICAL TRIAL LANDSCAPE

14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events

15 CALCIPHYLAXIS - MARKET SCENARIO

15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
  15.2.1 Calciphylaxis - Market Size
    15.2.1.1 Market Size (2018-2023)
    15.2.1.2 Market Forecast (2024-2034)
  15.2.2 Calciphylaxis - Market Size by Therapies
    15.2.2.1 Market Size by Therapies (2018-2023)
    15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
  15.3.1 Calciphylaxis - Market Size
    15.3.1.1 Market Size (2018-2023)
    15.3.1.2 Market Forecast (2024-2034)
  15.3.2 Calciphylaxis - Market Size by Therapies
    15.3.2.1 Market Size by Therapies (2018-2023)
    15.3.2.2 Market Forecast by Therapies (2024-2034)
  15.3.3 Calciphylaxis - Access and Reimbursement Overview
15.4 Market Scenario - Germany
  15.4.1 Calciphylaxis - Market Size
    15.4.1.1 Market Size (2018-2023)
    15.4.1.2 Market Forecast (2024-2034)
  15.4.2 Calciphylaxis - Market Size by Therapies
    15.4.2.1 Market Size by Therapies (2018-2023)
    15.4.2.2 Market Forecast by Therapies (2024-2034)
  15.4.3 Calciphylaxis - Access and Reimbursement Overview
15.5 Market Scenario - France
  15.5.1 Calciphylaxis - Market Size
    15.5.1.1 Market Size (2018-2023)
    15.5.1.2 Market Forecast (2024-2034)
  15.5.2 Calciphylaxis - Market Size by Therapies
    15.5.2.1 Market Size by Therapies (2018-2023)
    15.5.2.2 Market Forecast by Therapies (2024-2034)
  15.5.3 Calciphylaxis - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
  15.6.1 Calciphylaxis - Market Size
    15.6.1.1 Market Size (2018-2023)
    15.6.1.2 Market Forecast (2024-2034)
  15.6.2 Calciphylaxis - Market Size by Therapies
    15.6.2.1 Market Size by Therapies (2018-2023)
    15.6.2.2 Market Forecast by Therapies (2024-2034)
  15.6.3 Calciphylaxis - Access and Reimbursement Overview
15.7 Market Scenario - Italy
  15.7.1 Calciphylaxis - Market Size
    15.7.1.1 Market Size (2018-2023)
    15.7.1.2 Market Forecast (2024-2034)
  15.7.2 Calciphylaxis - Market Size by Therapies
    15.7.2.1 Market Size by Therapies (2018-2023)
    15.7.2.2 Market Forecast by Therapies (2024-2034)
  15.7.3 Calciphylaxis - Access and Reimbursement Overview
15.8 Market Scenario - Spain
  15.8.1 Calciphylaxis - Market Size
    15.8.1.1 Market Size (2018-2023)
    15.8.1.2 Market Forecast (2024-2034)
  15.8.2 Calciphylaxis - Market Size by Therapies
    15.8.2.1 Market Size by Therapies (2018-2023)
    15.8.2.2 Market Forecast by Therapies (2024-2034)
  15.8.3 Calciphylaxis - Access and Reimbursement Overview
15.9 Market Scenario - Japan
  15.9.1 Calciphylaxis - Market Size
    15.9.1.1 Market Size (2018-2023)
    15.9.1.2 Market Forecast (2024-2034)
  15.9.2 Calciphylaxis - Market Size by Therapies
    15.9.2.1 Market Size by Therapies (2018-2023)
    15.9.2.2 Market Forecast by Therapies (2024-2034)
  15.9.3 Calciphylaxis - Access and Reimbursement Overview

16 CALCIPHYLAXIS - RECENT EVENTS AND INPUTS FROM KEY OPINION LEADERS

17 CALCIPHYLAXIS MARKET - SWOT ANALYSIS

17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats

18 CALCIPHYLAXIS MARKET – STRATEGIC RECOMMENDATIONS

19 APPENDIX


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