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Botulism Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

May 2024 | 130 pages | ID: B1D11ED25F2EEN
IMARC Group

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The 7 major botulism markets reached a value of US$ 938.4 Million in 2023. Looking forward, IMARC Group expects the 7MM to reach US$ 1,642.8 Million by 2034, exhibiting a growth rate (CAGR) of 5.22% during 2024-2034.

The botulism market has been comprehensively analyzed in IMARC's new report titled "Botulism Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Botulism is a rare and potentially fatal disease that is triggered by a toxin produced by the bacterium Clostridium botulinum. The toxin damages the neurological system, including the brain, spinal cord, and nerves, and causes muscle weakness or paralysis. Foodborne, wound, and infant botulism are the three primary forms of this illness. The most prominent symptom of the disorder is a weakness that begins on both sides of the face, moves down to the neck, and then spreads throughout the rest of the body. The other common indications include double or blurred vision, difficulty swallowing, shortness of breath, drooping eyelids, slurred speech, etc. Infants with botulism may present symptoms like constipation, weak crying, floppy movements, etc. The diagnosis of the ailment involves a combination of clinical presentation, laboratory testing, and epidemiological investigation. Laboratory testing is used to confirm the diagnosis and may include tests to detect botulinum toxin in serum, stool, or wound specimens, or electromyography (EMG) to evaluate muscle function. Additionally, an epidemiological investigation may also be conducted to identify potential sources of exposure to the toxin.

The increasing prevalence of intestinal and wound infections among individuals, which serve as pathways for bacteria spores to enter the body and produce toxins, is primarily driving the botulism market. Besides this, the rising consumer preference for preserved and canned foods, such as processed cheese, fish, mushrooms, etc., which provide an optimal environment for bacteria to survive and elevate the disease risk, is also propelling the market growth. Additionally, the widespread adoption of various antitoxins and antibiotics, that neutralize the toxin produced by the bacterium and prevent further damage to the body, is acting as another significant growth-inducing factor. Apart from this, the growing emphasis on enhancing diagnostic capabilities since early diagnosis allows for prompt initiation of treatment and can improve outcomes is also bolstering the market growth. Furthermore, numerous key players are making extensive investments in developing more effective and efficient antitoxins, including monoclonal antibodies that are specifically designed to target and neutralize the botulinum toxin. This, in turn, is creating a positive outlook for the market. In addition to this, the emerging popularity of cholinergic agonists, such as guanidine and 3,4-diaminopyridine, which stimulate acetylcholine release and help to counteract the effects of the toxin as well as improve muscle strength, is expected to drive the botulism market in the coming years.

IMARC Group's new report provides an exhaustive analysis of the botulism market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for botulism and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the botulism market in any manner.

Time Period of the Study

Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034

Countries Covered

United States
Germany
France
United Kingdom
Italy
Spain
Japan

Analysis Covered Across Each Country

Historical, current, and future epidemiology scenario
Historical, current, and future performance of the botulism market
Historical, current, and future performance of various therapeutic categories in the market
Sales of various drugs across the botulism market
Reimbursement scenario in the market
In-market and pipeline drugs
Competitive Landscape:
This report also provides a detailed analysis of the current botulism marketed drugs and late-stage pipeline drugs.

In-Market Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.

Key Questions Answered in this Report:
Market Insights

How has the botulism market performed so far and how will it perform in the coming years?
What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
What was the country-wise size of the botulism market across the seven major markets in 2023 and what will it look like in 2034?
What is the growth rate of the botulism market across the seven major markets and what will be the expected growth over the next ten years?
What are the key unmet needs in the market?

Epidemiology Insights

What is the number of prevalent cases (2018-2034) of botulism across the seven major markets?
What is the number of prevalent cases (2018-2034) of botulism by age across the seven major markets?
What is the number of prevalent cases (2018-2034) of botulism by gender across the seven major markets?
What is the number of prevalent cases (2018-2034) of botulism by type across the seven major markets?
How many patients are diagnosed (2018-2034) with botulism across the seven major markets?
What is the size of the botulism patient pool (2018-2023) across the seven major markets?
What would be the forecasted patient pool (2024-2034) across the seven major markets?
What are the key factors driving the epidemiological trend of botulism?
What will be the growth rate of patients across the seven major markets?

Botulism: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

What are the current marketed drugs and what are their market performance?
What are the key pipeline drugs and how are they expected to perform in the coming years?
How safe are the current marketed drugs and what are their efficacies?
How safe are the late-stage pipeline drugs and what are their efficacies?
What are the current treatment guidelines for botulism drugs across the seven major markets?
Who are the key companies in the market and what are their market shares?
What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the botulism market?
What are the key regulatory events related to the botulism market?
What is the structure of clinical trial landscape by status related to the botulism market?
What is the structure of clinical trial landscape by phase related to the botulism market?
What is the structure of clinical trial landscape by route of administration related to the botulism market?
?1 Preface

2 SCOPE AND METHODOLOGY

2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
  2.3.1 Primary Sources
  2.3.2 Secondary Sources
2.4 Market Estimation
  2.4.1 Bottom-Up Approach
  2.4.2 Top-Down Approach
2.5 Forecasting Methodology

3 EXECUTIVE SUMMARY

4 BOTULISM - INTRODUCTION

4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence

5 BOTULISM - DISEASE OVERVIEW

5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment

6 PATIENT JOURNEY

7 BOTULISM - EPIDEMIOLOGY AND PATIENT POPULATION

7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
  7.2.1 Epidemiology Scenario (2018-2023)
  7.2.2 Epidemiology Forecast (2024-2034)
  7.2.3 Epidemiology by Age (2018-2034)
  7.2.4 Epidemiology by Gender (2018-2034)
  7.2.5 Epidemiology by Type (2018-2034)
  7.2.6 Diagnosed Cases (2018-2034)
  7.2.7 Patient Pool/Treated Cases (2018-2034)
7.3 Epidemiology Scenario - United States
  7.3.1 Epidemiology Scenario (2018-2023)
  7.3.2 Epidemiology Forecast (2024-2034)
  7.3.3 Epidemiology by Age (2018-2034)
  7.3.4 Epidemiology by Gender (2018-2034)
  7.3.5 Epidemiology by Type (2018-2034)
  7.3.6 Diagnosed Cases (2018-2034)
  7.3.7 Patient Pool/Treated Cases (2018-2034)
7.4 Epidemiology Scenario - Germany
  7.4.1 Epidemiology Scenario (2018-2023)
  7.4.2 Epidemiology Forecast (2024-2034)
  7.4.3 Epidemiology by Age (2018-2034)
  7.4.4 Epidemiology by Gender (2018-2034)
  7.4.5 Epidemiology by Type (2018-2034)
  7.4.6 Diagnosed Cases (2018-2034)
  7.4.7 Patient Pool/Treated Cases (2018-2034)
7.5 Epidemiology Scenario - France
  7.5.1 Epidemiology Scenario (2018-2023)
  7.5.2 Epidemiology Forecast (2024-2034)
  7.5.3 Epidemiology by Age (2018-2034)
  7.5.4 Epidemiology by Gender (2018-2034)
  7.5.5 Epidemiology by Type (2018-2034)
  7.5.6 Diagnosed Cases (2018-2034)
  7.5.7 Patient Pool/Treated Cases (2018-2034)
7.6 Epidemiology Scenario - United Kingdom
  7.6.1 Epidemiology Scenario (2018-2023)
  7.6.2 Epidemiology Forecast (2024-2034)
  7.6.3 Epidemiology by Age (2018-2034)
  7.6.4 Epidemiology by Gender (2018-2034)
  7.6.5 Epidemiology by Type (2018-2034)
  7.6.6 Diagnosed Cases (2018-2034)
  7.6.7 Patient Pool/Treated Cases (2018-2034)
7.7 Epidemiology Scenario - Italy
  7.7.1 Epidemiology Scenario (2018-2023)
  7.7.2 Epidemiology Forecast (2024-2034)
  7.7.3 Epidemiology by Age (2018-2034)
  7.7.4 Epidemiology by Gender (2018-2034)
  7.7.5 Epidemiology by Type (2018-2034)
  7.7.6 Diagnosed Cases (2018-2034)
  7.7.7 Patient Pool/Treated Cases (2018-2034)
7.8 Epidemiology Scenario - Spain
  7.8.1 Epidemiology Scenario (2018-2023)
  7.8.2 Epidemiology Forecast (2024-2034)
  7.8.3 Epidemiology by Age (2018-2034)
  7.8.4 Epidemiology by Gender (2018-2034)
  7.8.5 Epidemiology by Type (2018-2034)
  7.8.6 Diagnosed Cases (2018-2034)
  7.8.7 Patient Pool/Treated Cases (2018-2034)
7.9 Epidemiology Scenario - Japan
  7.9.1 Epidemiology Scenario (2018-2023)
  7.9.2 Epidemiology Forecast (2024-2034)
  7.9.3 Epidemiology by Age (2018-2034)
  7.9.4 Epidemiology by Gender (2018-2034)
  7.9.5 Epidemiology by Type (2018-2034)
  7.9.6 Diagnosed Cases (2018-2034)
  7.9.7 Patient Pool/Treated Cases (2018-2034)

8 BOTULISM - TREATMENT ALGORITHM, GUIDELINES, AND MEDICAL PRACTICES

8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm

9 BOTULISM - UNMET NEEDS

10 BOTULISM - KEY ENDPOINTS OF TREATMENT

11 BOTULISM - MARKETED PRODUCTS

11.1 List of Botulism Marketed Drugs Across the Top 7 Markets
  11.1.1 BAT (Botulinum antitoxin heptavalent) - Emergent BioSolutions
    11.1.1.1 Drug Overview
    11.1.1.2 Mechanism of Action
    11.1.1.3 Regulatory Status
    11.1.1.4 Clinical Trial Results
    11.1.1.5 Sales Across Major Markets
  11.1.2 BabyBIG (Botulism immune globulin)
    11.1.2.1 Drug Overview
    11.1.2.2 Mechanism of Action
    11.1.2.3 Regulatory Status
    11.1.2.4 Clinical Trial Results
    11.1.2.5 Sales Across Major Markets
Kindly note that the above only represents a partial list of marketed drugs, and the complete list has been provided in the report.

12 BOTULISM - PIPELINE DRUGS

12.1 List of Botulism Pipeline Drugs Across the Top 7 Markets
  12.1.1 Drug Name – Company Name
    12.1.1.1 Drug Overview
    12.1.1.2 Mechanism of Action
    12.1.1.3 Clinical Trial Results
    12.1.1.4 Safety and Efficacy
    12.1.1.5 Regulatory Status
Kindly note that the complete list of pipeline drugs has been provided in the report.

13. BOTULISM - ATTRIBUTE ANALYSIS OF KEY MARKETED AND PIPELINE DRUGS

14. BOTULISM – CLINICAL TRIAL LANDSCAPE

14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events

15 BOTULISM - MARKET SCENARIO

15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
  15.2.1 Botulism - Market Size
    15.2.1.1 Market Size (2018-2023)
    15.2.1.2 Market Forecast (2024-2034)
  15.2.2 Botulism - Market Size by Therapies
    15.2.2.1 Market Size by Therapies (2018-2023)
    15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
  15.3.1 Botulism - Market Size
    15.3.1.1 Market Size (2018-2023)
    15.3.1.2 Market Forecast (2024-2034)
  15.3.2 Botulism - Market Size by Therapies
    15.3.2.1 Market Size by Therapies (2018-2023)
    15.3.2.2 Market Forecast by Therapies (2024-2034)
  15.3.3 Botulism - Access and Reimbursement Overview
15.4 Market Scenario - Germany
  15.4.1 Botulism - Market Size
    15.4.1.1 Market Size (2018-2023)
    15.4.1.2 Market Forecast (2024-2034)
  15.4.2 Botulism - Market Size by Therapies
    15.4.2.1 Market Size by Therapies (2018-2023)
    15.4.2.2 Market Forecast by Therapies (2024-2034)
  15.4.3 Botulism - Access and Reimbursement Overview
15.5 Market Scenario - France
  15.5.1 Botulism - Market Size
    15.5.1.1 Market Size (2018-2023)
    15.5.1.2 Market Forecast (2024-2034)
  15.5.2 Botulism - Market Size by Therapies
    15.5.2.1 Market Size by Therapies (2018-2023)
    15.5.2.2 Market Forecast by Therapies (2024-2034)
  15.5.3 Botulism - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
  15.6.1 Botulism - Market Size
    15.6.1.1 Market Size (2018-2023)
    15.6.1.2 Market Forecast (2024-2034)
  15.6.2 Botulism - Market Size by Therapies
    15.6.2.1 Market Size by Therapies (2018-2023)
    15.6.2.2 Market Forecast by Therapies (2024-2034)
  15.6.3 Botulism - Access and Reimbursement Overview
15.7 Market Scenario - Italy
  15.7.1 Botulism - Market Size
    15.7.1.1 Market Size (2018-2023)
    15.7.1.2 Market Forecast (2024-2034)
  15.7.2 Botulism - Market Size by Therapies
    15.7.2.1 Market Size by Therapies (2018-2023)
    15.7.2.2 Market Forecast by Therapies (2024-2034)
  15.7.3 Botulism - Access and Reimbursement Overview
15.8 Market Scenario - Spain
  15.8.1 Botulism - Market Size
    15.8.1.1 Market Size (2018-2023)
    15.8.1.2 Market Forecast (2024-2034)
  15.8.2 Botulism - Market Size by Therapies
    15.8.2.1 Market Size by Therapies (2018-2023)
    15.8.2.2 Market Forecast by Therapies (2024-2034)
  15.8.3 Botulism - Access and Reimbursement Overview
15.9 Market Scenario - Japan
  15.9.1 Botulism - Market Size
    15.9.1.1 Market Size (2018-2023)
    15.9.1.2 Market Forecast (2024-2034)
  15.9.2 Botulism - Market Size by Therapies
    15.9.2.1 Market Size by Therapies (2018-2023)
    15.9.2.2 Market Forecast by Therapies (2024-2034)
  15.9.3 Botulism - Access and Reimbursement Overview

16 BOTULISM - RECENT EVENTS AND INPUTS FROM KEY OPINION LEADERS

17 BOTULISM MARKET - SWOT ANALYSIS

17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats

18 BOTULISM MARKET – STRATEGIC RECOMMENDATIONS

19 APPENDIX


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