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Bone Marrow Failure Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

May 2024 | 128 pages | ID: B2D08922480FEN
IMARC Group

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The 7 major bone marrow failure markets are expected to exhibit a CAGR of 6.82% during 2024-2034.

The bone marrow failure market has been comprehensively analyzed in IMARC's new report titled "Bone Marrow Failure Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Bone marrow failure refers to a condition in which there's a decrease in the production of one or more types of blood cells. This disease can result in low counts of red blood cells that can cause fatigue, weakness, and shortness of breath. It can also lead to a decreased number of white blood cells, making patients more susceptible to infections, and a reduced level of platelets, increasing the tendency to bleed and bruise easily. Numerous other symptoms of the illness include pale skin, small red spots under the skin, an enlarged liver or spleen, etc. The diagnosis of bone marrow failure typically involves a thorough medical history review, clinical feature evaluation, and physical examination. The healthcare provider may also perform a flow cytometry technique that uses fluorescently labeled antibodies to analyze the characteristics of cells and determine the presence of specific markers associated with the disease. Furthermore, a bone marrow aspiration and biopsy are conducted to assess the cellularity and detect if there are any abnormalities in the formation of blood cells.

The increasing cases of inherited syndromes, which can damage and interfere with the normal functioning of the bone marrow, leading to inadequate production of blood cells, are primarily driving the bone marrow failure market. In addition to this, the rising prevalence of several risk factors, such as exposure to toxins and hazardous chemicals, vitamin deficiencies, viral infections, certain medications, etc., is also creating a positive outlook for the market. Moreover, the widespread adoption of stem cell transplantation, which involves replacing the malfunctioning bone marrow with healthy tissues to restore normal blood cell production, is further bolstering the market growth. Apart from this, the inflating application of effective immunosuppressants, like anti-thymocyte globulin and cyclosporine, to help in reducing the activity of the immune system and decreasing inflammation in individuals suffering from the ailment is acting as another significant growth-inducing factor. Additionally, the emerging popularity of androgenic hormone therapy, since it can minimize the complications of the condition by stimulating erythropoiesis and promoting overall blood cell counts, is expected to drive the bone marrow failure market during the forecast period.

IMARC Group's new report provides an exhaustive analysis of the bone marrow failure market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for bone marrow failure and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the bone marrow failure market in any manner.

Time Period of the Study

Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034

Countries Covered

United States
Germany
France
United Kingdom
Italy
Spain
Japan

Analysis Covered Across Each Country

Historical, current, and future epidemiology scenario
Historical, current, and future performance of the bone marrow failure market
Historical, current, and future performance of various therapeutic categories in the market
Sales of various drugs across the bone marrow failure market
Reimbursement scenario in the market
In-market and pipeline drugs
Competitive Landscape:
This report also provides a detailed analysis of the current bone marrow failure marketed drugs and late-stage pipeline drugs.

In-Market Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.

Key Questions Answered in this Report:
Market Insights

How has the bone marrow failure market performed so far and how will it perform in the coming years?
What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
What was the country-wise size of the bone marrow failure market across the seven major markets in 2023 and what will it look like in 2034?
What is the growth rate of the bone marrow failure market across the seven major markets and what will be the expected growth over the next ten years?
What are the key unmet needs in the market?

Epidemiology Insights

What is the number of prevalent cases (2018-2034) of bone marrow failure across the seven major markets?
What is the number of prevalent cases (2018-2034) of bone marrow failure by age across the seven major markets?
What is the number of prevalent cases (2018-2034) of bone marrow failure by gender across the seven major markets?
How many patients are diagnosed (2018-2034) with bone marrow failure across the seven major markets?
What is the size of the bone marrow failure patient pool (2018-2023) across the seven major markets?
What would be the forecasted patient pool (2024-2034) across the seven major markets?
What are the key factors driving the epidemiological trend of bone marrow failure?
What will be the growth rate of patients across the seven major markets?

Bone Marrow Failure: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

What are the current marketed drugs and what are their market performance?
What are the key pipeline drugs and how are they expected to perform in the coming years?
How safe are the current marketed drugs and what are their efficacies?
How safe are the late-stage pipeline drugs and what are their efficacies?
What are the current treatment guidelines for bone marrow failure drugs across the seven major markets?
Who are the key companies in the market and what are their market shares?
What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the bone marrow failure market?
What are the key regulatory events related to the bone marrow failure market?
What is the structure of clinical trial landscape by status related to the bone marrow failure market?
What is the structure of clinical trial landscape by phase related to the bone marrow failure market?
What is the structure of clinical trial landscape by route of administration related to the bone marrow failure market?
1 PREFACE

2 SCOPE AND METHODOLOGY

2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
  2.3.1 Primary Sources
  2.3.2 Secondary Sources
2.4 Market Estimation
  2.4.1 Bottom-Up Approach
  2.4.2 Top-Down Approach
2.5 Forecasting Methodology

3 EXECUTIVE SUMMARY

4 BONE MARROW FAILURE - INTRODUCTION

4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence

5 BONE MARROW FAILURE - DISEASE OVERVIEW

5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment

6 PATIENT JOURNEY

7 BONE MARROW FAILURE - EPIDEMIOLOGY AND PATIENT POPULATION

7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
  7.2.1 Epidemiology Scenario (2018-2023)
  7.2.2 Epidemiology Forecast (2024-2034)
  7.2.3 Epidemiology by Age (?2018-2034?)
  7.2.4 Epidemiology by Gender (?2018-2034?)
  7.2.5 Diagnosed Cases (?2018-2034?)
  7.2.6 Patient Pool/Treated Cases (?2018-2034?)
7.3 Epidemiology Scenario - United States
  7.3.1 Epidemiology Scenario (2018-2023)
  7.3.2 Epidemiology Forecast (2024-2034)
  7.3.3 Epidemiology by Age (?2018-2034?)
  7.3.4 Epidemiology by Gender (?2018-2034?)
  7.3.5 Diagnosed Cases (?2018-2034?)
  7.3.6 Patient Pool/Treated Cases (?2018-2034?)
7.4 Epidemiology Scenario - Germany
  7.4.1 Epidemiology Scenario (2018-2023)
  7.4.2 Epidemiology Forecast (2024-2034)
  7.4.3 Epidemiology by Age (?2018-2034?)
  7.4.4 Epidemiology by Gender (?2018-2034?)
  7.4.5 Diagnosed Cases (?2018-2034?)
  7.4.6 Patient Pool/Treated Cases (?2018-2034?)
7.5 Epidemiology Scenario - France
  7.5.1 Epidemiology Scenario (2018-2023)
  7.5.2 Epidemiology Forecast (2024-2034)
  7.5.3 Epidemiology by Age (?2018-2034?)
  7.5.4 Epidemiology by Gender (?2018-2034?)
  7.5.5 Diagnosed Cases (?2018-2034?)
  7.5.6 Patient Pool/Treated Cases (?2018-2034?)
7.6 Epidemiology Scenario - United Kingdom
  7.6.1 Epidemiology Scenario (2018-2023)
  7.6.2 Epidemiology Forecast (2024-2034)
  7.6.3 Epidemiology by Age (?2018-2034?)
  7.6.4 Epidemiology by Gender (?2018-2034?)
  7.6.5 Diagnosed Cases (?2018-2034?)
  7.6.6 Patient Pool/Treated Cases (?2018-2034?)
7.7 Epidemiology Scenario - Italy
  7.7.1 Epidemiology Scenario (2018-2023)
  7.7.2 Epidemiology Forecast (2024-2034)
  7.7.3 Epidemiology by Age (?2018-2034?)
  7.7.4 Epidemiology by Gender (?2018-2034?)
  7.7.5 Diagnosed Cases (?2018-2034?)
  7.7.6 Patient Pool/Treated Cases (?2018-2034?)
7.8 Epidemiology Scenario - Spain
  7.8.1 Epidemiology Scenario (2018-2023)
  7.8.2 Epidemiology Forecast (2024-2034)
  7.8.3 Epidemiology by Age (?2018-2034?)
  7.8.4 Epidemiology by Gender (?2018-2034?)
  7.8.5 Diagnosed Cases (?2018-2034?)
  7.8.6 Patient Pool/Treated Cases (?2018-2034?)
7.9 Epidemiology Scenario - Japan
  7.9.1 Epidemiology Scenario (2018-2023)
  7.9.2 Epidemiology Forecast (2024-2034)
  7.9.3 Epidemiology by Age (?2018-2034?)
  7.9.4 Epidemiology by Gender (?2018-2034?)
  7.9.5 Diagnosed Cases (?2018-2034?)
  7.9.6 Patient Pool/Treated Cases (?2018-2034?)

8 BONE MARROW FAILURE - TREATMENT ALGORITHM, GUIDELINES, AND MEDICAL PRACTICES

8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm

9 BONE MARROW FAILURE - UNMET NEEDS

10 BONE MARROW FAILURE - KEY ENDPOINTS OF TREATMENT

11 BONE MARROW FAILURE - MARKETED PRODUCTS

11.1 List of Bone Marrow Failure Marketed Drugs Across the Top 7 Markets
  11.1.1 Drug Name – Company Name
    11.1.1.1 Drug Overview
    11.1.1.2 Mechanism of Action
    11.1.1.3 Regulatory Status
    11.1.1.4 Clinical Trial Results
    11.1.1.5 Sales Across Major Markets
Kindly note that the complete list of marketed drugs has been provided in the report.

12 BONE MARROW FAILURE - PIPELINE DRUGS

12.1 List of Bone Marrow Failure Pipeline Drugs Across the Top 7 Markets
  12.1.1 EXG 34217 - Elixirgen
    12.1.1.1 Drug Overview
    12.1.1.2 Mechanism of Action
    12.1.1.3 Clinical Trial Results
    12.1.1.4 Safety and Efficacy
    12.1.1.5 Regulatory Status
  12.1.2 CK0801 - Cellenkos
    12.1.2.1 Drug Overview
    12.1.2.2 Mechanism of Action
    12.1.2.3 Clinical Trial Results
    12.1.2.4 Safety and Efficacy
    12.1.2.5 Regulatory Status
Kindly note that the above only represents a partial list of pipeline drugs, and the complete list has been provided in the report.

13. BONE MARROW FAILURE - ATTRIBUTE ANALYSIS OF KEY MARKETED AND PIPELINE DRUGS

14. BONE MARROW FAILURE – CLINICAL TRIAL LANDSCAPE14.1 DRUGS BY STATUS

14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events

15 BONE MARROW FAILURE - MARKET SCENARIO

15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
  15.2.1 Bone Marrow Failure - Market Size
    15.2.1.1 Market Size (2018-2023)
    15.2.1.2 Market Forecast (2024-2034)
  15.2.2 Bone Marrow Failure - Market Size by Therapies
    15.2.2.1 Market Size by Therapies (2018-2023)
    15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
  15.3.1 Bone Marrow Failure - Market Size
    15.3.1.1 Market Size (2018-2023)
    15.3.1.2 Market Forecast (2024-2034)
  15.3.2 Bone Marrow Failure - Market Size by Therapies
    15.3.2.1 Market Size by Therapies (2018-2023)
    15.3.2.2 Market Forecast by Therapies(2024-2034)
  15.3.3 Bone Marrow Failure - Access and Reimbursement Overview
15.4 Market Scenario - Germany
  15.4.1 Bone Marrow Failure - Market Size
    15.4.1.1 Market Size (2018-2023)
    15.4.1.2 Market Forecast (2024-2034)
  15.4.2 Bone Marrow Failure - Market Size by Therapies
    15.4.2.1 Market Size by Therapies (2018-2023)
    15.4.2.2 Market Forecast by Therapies (2024-2034)
  15.4.3 Bone Marrow Failure - Access and Reimbursement Overview
15.5 Market Scenario - France
  15.5.1 Bone Marrow Failure - Market Size
    15.5.1.1 Market Size (2018-2023)
    15.5.1.2 Market Forecast (2024-2034)
  15.5.2 Bone Marrow Failure - Market Size by Therapies
    15.5.2.1 Market Size by Therapies (2018-2023)
    15.5.2.2 Market Forecast by Therapies (2024-2034)
  15.5.3 Bone Marrow Failure - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
  15.6.1 Bone Marrow Failure - Market Size
    15.6.1.1 Market Size (2018-2023)
    15.6.1.2 Market Forecast (2024-2034)
  15.6.2 Bone Marrow Failure - Market Size by Therapies
    15.6.2.1 Market Size by Therapies (2018-2023)
    15.6.2.2 Market Forecast by Therapies (2024-2034)
  15.6.3 Bone Marrow Failure - Access and Reimbursement Overview
15.7 Market Scenario - Italy
  15.7.1 Bone Marrow Failure - Market Size
    15.7.1.1 Market Size (2018-2023)
    15.7.1.2 Market Forecast2024-2034)
  15.7.2 Bone Marrow Failure - Market Size by Therapies
    15.7.2.1 Market Size by Therapies (2018-2023)
    15.7.2.2 Market Forecast by Therapies (2024-2034)
  15.7.3 Bone Marrow Failure - Access and Reimbursement Overview
15.8 Market Scenario - Spain
  15.8.1 Bone Marrow Failure - Market Size
    15.8.1.1 Market Size (2018-2023)
    15.8.1.2 Market Forecast (2024-2034)
  15.8.2 Bone Marrow Failure - Market Size by Therapies
    15.8.2.1 Market Size by Therapies (2018-2023)
    15.8.2.2 Market Forecast by Therapies (2024-2034)
  15.8.3 Bone Marrow Failure - Access and Reimbursement Overview
15.9 Market Scenario - Japan
  15.9.1 Bone Marrow Failure - Market Size
    15.9.1.1 Market Size (2018-2023)
    15.9.1.2 Market Forecast (2024-2034)
  15.9.2 Bone Marrow Failure - Market Size by Therapies
    15.9.2.1 Market Size by Therapies (2018-2023)
    15.9.2.2 Market Forecast by Therapies (2024-2034)
  15.9.3 Bone Marrow Failure - Access and Reimbursement Overview

16 BONE MARROW FAILURE - RECENT EVENTS AND INPUTS FROM KEY OPINION LEADERS

17 BONE MARROW FAILURE MARKET - SWOT ANALYSIS

17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats

18 BONE MARROW FAILURE MARKET – STRATEGIC RECOMMENDATIONS

19 APPENDIX


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