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Bone Graft and Substitutes Market: Global Industry Trends, Share, Size, Growth, Opportunity and Forecast 2022-2027

June 2022 | 105 pages | ID: B4C1C8DB5030EN
IMARC Group

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The global bone graft and substitutes market reached a value of US$ 2.8 Billion in 2021. Looking forward, IMARC Group expects the market to reach US$ 4.0 Billion by 2027, exhibiting a CAGR of 6.2% during 2022-2027. Keeping in mind the uncertainties of COVID-19, we are continuously tracking and evaluating the direct as well as the indirect influence of the pandemic on different end use sectors. These insights are included in the report as a major market contributor.

Bone graft and substitutes are utilized for replacing missing bones or repairing bone fractures. They comprise an osteoconductive matrix that acts as a filler to promote wound healing; osteoinductive proteins which support mitogenesis of identical bone cells; and osteogenic cells that form the bone in the appropriate environment. They are bioresorbable in nature and cause no antigen-antibody reaction. Owing to these attributes, they are widely used for healing fractures and bone injuries, and in spinal, facial, foot, ankle or trauma surgeries.
One of the key trends witnessed in the market is the advent of new polymer and ceramic products that have biologically superior characteristics. The introduction of new manufacturing technologies, such as rapid prototyping or 3D printing, is also helping in the fabrication of free-form biomaterial scaffolds for tissue regeneration. Additionally, the demand for bone graft and substitutes is increasing owing to high morbidity rates, growing geriatric population and the increasing cases of osteoarthritis. Apart from this, a shift towards minimally invasive procedures, coupled with the growing awareness among patients about the benefits of bone regeneration through biologics is further strengthening the market growth. Some of the other growth-inducing factors include the availability of advanced products in different shapes and sizes, rising prevalence of orthopedic problems and periodontal diseases, and increasing number of studies for investigating the enhancement of bioactivity of bone graft substitutes.

Key Market Segmentation:
IMARC Group provides an analysis of the key trends in each sub-segment of the global bone graft and substitutes market, along with forecasts at the global and regional level from 2022-2027. Our report has categorized the market based on material type, application and end user.

Breakup by Material Type:

Allografts
Machined Allografts
Demineralized Bone Matrix (DBMs)
Bone Graft Substitutes
Bone Morphogenic Proteins (BMPs)
Synthetic Bone Grafts
Cell-based Matrices
Others

Breakup by Application:

Spinal Fusion
Trauma
Joint Reconstruction
Foot and Ankle
Dental Bone Grafting
Craniomaxillofacial
Others

Breakup by End User:
Hospitals
Surgical Centres
Clinics
Others

Breakup by Region:
North America
Europe
Asia Pacific
Middle East and Africa
Latin America

Competitive Landscape:

The report has also analysed the competitive landscape of the market with some of the key players being Zimmer Biomet Dental, DePuy Synthes, Wright Medical Technology, Medtronic Plc., Stryker Corporation, NuVasive Inc., Arthrex Inc., Integra LifeSciences, Baxter International Inc., Musculoskeletal Transplant Foundation, Bacterin International Holdings, SeaSpine, LifeNet Health, etc.

Key Questions Answered in This Report:

How has the global bone graft and substitutes market performed so far and how will it perform in the coming years?
What are the key regional markets in the global bone graft and substitutes industry?
What has been the impact of COVID-19 on the global bone graft and substitutes industry?
What is the breakup of the market based on the material type?
What is the breakup of the market based on the application?
What is the breakup of the market based on the end user?
What are the various stages in the value chain of the global bone graft and substitutes industry?
What are the key driving factors and challenges in the global bone graft and substitutes industry?
What is the structure of the global bone graft and substitutes industry and who are the key players?
What is the degree of competition in the global bone graft and substitutes industry?
1 PREFACE

2 SCOPE AND METHODOLOGY

2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
  2.3.1 Primary Sources
  2.3.2 Secondary Sources
2.4 Market Estimation
  2.4.1 Bottom-Up Approach
  2.4.2 Top-Down Approach
2.5 Forecasting Methodology

3 EXECUTIVE SUMMARY

4 INTRODUCTION

4.1 Overview
4.2 Key Industry Trends

5 GLOBAL BONE GRAFT AND SUBSTITUTE MARKET

5.1 Market Overview
5.2 Market Performance
5.3 Impact of COVID-19
5.4 Market Breakup by Material Type
5.5 Market Breakup by Application
5.6 Market Breakup by End User
5.7 Market Breakup by Region
5.8 Market Forecast

6 MARKET BREAKUP BY MATERIAL TYPE

6.1 Allografts
  6.1.1 Market Trends
  6.1.2 Market Breakup By Type
    6.1.2.1 Machined Allografts
      6.1.2.1.1 Market Trends
      6.1.2.1.2 Market Forecast
    6.1.2.2 Demineralized Bone Matrix (DBMs)
      6.1.2.2.1 Market Trends
      6.1.2.2.2 Market Forecast
  6.1.3 Market Forecast
6.2 Bone Graft Substitutes
  6.2.1 Market Trends
  6.2.2 Market Breakup By Type
    6.2.2.1 Bone Morphogenic Proteins (BMPs)
      6.2.2.1.1 Market Trends
      6.2.2.1.2 Market Forecast
    6.1.2.2 Synthetic Bone Grafts
      6.2.2.2.1 Market Trends
      6.2.2.2.2 Market Forecast
  6.2.3 Market Forecast
6.3 Cell-based Matrices
  6.3.1 Market Trends
  6.3.2 Market Forecast
6.4 Others
  6.4.1 Market Trends
  6.4.2 Market Forecast

7 MARKET BREAKUP BY APPLICATION

7.1 Spinal Fusion
  7.1.1 Market Trends
  7.1.2 Market Forecast
7.2 Trauma
  7.2.1 Market Trends
  7.2.2 Market Forecast
7.3 Joint Reconstruction
  7.3.1 Market Trends
  7.3.2 Market Forecast
7.4 Foot and Ankle
  7.4.1 Market Trends
  7.4.2 Market Forecast
7.5 Dental Bone Grafting
  7.5.1 Market Trends
  7.5.2 Market Forecast
7.6 Craniomaxillofacial
  7.6.1 Market Trends
  7.6.2 Market Forecast
7.7 Others
  7.7.1 Market Trends
  7.7.2 Market Forecast

8 MARKET BREAKUP BY END USER

8.1 Hospitals
  8.1.1 Market Trends
  8.1.2 Market Forecast
8.2 Surgical Centres
  8.2.1 Market Trends
  8.2.2 Market Forecast
8.3 Clinics
  8.3.1 Market Trends
  8.3.2 Market Forecast
8.4 Others
  8.4.1 Market Trends
  8.4.2 Market Forecast

9 MARKET BREAKUP BY REGION

9.1 North America
  9.1.1 Market Trends
  9.1.2 Market Forecast
9.2 Europe
  9.2.1 Market Trends
  9.2.2 Market Forecast
9.3 Asia Pacific
  9.3.1 Market Trends
  9.3.2 Market Forecast
9.4 Middle East and Africa
  9.4.1 Market Trends
  9.4.2 Market Forecast
9.5 Latin America
  9.5.1 Market Trends
  9.5.2 Market Forecast

10 SWOT ANALYSIS

10.1 Overview
10.2 Strengths
10.3 Weaknesses
10.4 Opportunities
10.5 Threats

11 VALUE CHAIN ANALYSIS

12 PORTERS FIVE FORCES ANALYSIS

12.1 Overview
12.2 Bargaining Power of Buyers
12.3 Bargaining Power of Suppliers
12.4 Degree of Competition
12.5 Threat of New Entrants
12.6 Threat of Substitutes

13 PRICE ANALYSIS

14 COMPETITIVE LANDSCAPE

14.1 Market Structure
14.2 Key Players
14.3 Profiles of Key Players
  14.3.1 Zimmer Biomet Dental
  14.3.2 DePuy Synthes
  14.3.3 Wright Medical Technology
  14.3.4 Medtronic Plc.
  14.3.5 Stryker Corporation
  14.3.6 NuVasive Inc.
  14.3.7 Arthrex Inc.
  14.3.8 Integra LifeSciences
  14.3.9 Baxter International Inc.
  14.3.10 Musculoskeletal Transplant Foundation
  14.3.11 Bacterin International Holdings
  14.3.12 SeaSpine
  14.3.13 LifeNet Health

LIST OF TABLES

Table 1: Global: Bone Graft and Substitute Market: Key Industry Highlights, 2021 and 2027
Table 2: Global: Bone Graft and Substitute Market Forecast: Breakup by Material Type (in Million US$), 2022-2027
Table 3: Global: Bone Graft and Substitute Market Forecast: Breakup by Application (in Million US$), 2022-2027
Table 4: Global: Bone Graft and Substitute Market Forecast: Breakup by End User (in Million US$), 2022-2027
Table 5: Global: Bone Graft and Substitute Market Forecast: Breakup by Region (in Million US$), 2022-2027
Table 6: Global: Bone Graft and Substitute Market: Competitive Structure
Table 7: Global: Bone Graft and Substitute Market: Key Players

LIST OF FIGURES

Figure 1: Global: Bone Graft and Substitute Market: Major Drivers and Challenges
Figure 2: Global: Bone Graft and Substitute Market: Sales Value (in Billion US$), 2016 - 2021
Figure 3: Global: Bone Graft and Substitute Market: Breakup by Material Type (in %), 2021
Figure 4: Global: Bone Graft and Substitute Market: Breakup by Application (in %), 2021
Figure 5: Global: Bone Graft and Substitute Market: Breakup by End User (in %), 2021
Figure 6: Global: Bone Graft and Substitute Market: Breakup by Region (in %), 2021
Figure 7: Global: Bone Graft and Substitute Market Forecast: Sales Value (in Billion US$), 2022-2027
Figure 8: Global: Bone Graft and Substitute Industry: SWOT Analysis
Figure 9: Global: Bone Graft and Substitute Industry: Value Chain Analysis
Figure 10: Global: Bone Graft and Substitute Industry: Porter’s Five Forces Analysis
Figure 11: Global: Bone Graft and Substitute (Allografts) Market: Sales Value (in Million US$), 2016 & 2021
Figure 12: Global: Bone Graft and Substitute (Allografts) Market: Breakup by Type (in %), 2021
Figure 13: Global: Bone Graft and Substitute (Machined Allografts) Market: Sales Value (in Million US$), 2016 & 2021
Figure 14: Global: Bone Graft and Substitute (Machined Allografts) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 15: Global: Bone Graft and Substitute (Demineralized Bone Matrix-DBMs) Market: Sales Value (in Million US$), 2016 & 2021
Figure 16: Global: Bone Graft and Substitute (Demineralized Bone Matrix-DBMs) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 17: Global: Bone Graft and Substitute (Allografts) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 18: Global: Bone Graft and Substitute (Bone Graft Substitutes) Market: Sales Value (in Million US$), 2016 & 2021
Figure 19: Global: Bone Graft and Substitute (Bone Graft Substitutes) Market: Breakup by Type (in %), 2021
Figure 20: Global: Bone Graft and Substitute (Bone Morphogenic Proteins-BMPs) Market: Sales Value (in Million US$), 2016 & 2021
Figure 21: Global: Bone Graft and Substitute (Bone Morphogenic Proteins-BMPs) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 22: Global: Bone Graft and Substitute (Synthetic Bone Grafts) Market: Sales Value (in Million US$), 2016 & 2021
Figure 23: Global: Bone Graft and Substitute (Synthetic Bone Grafts) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 24: Global: Bone Graft and Substitute (Bone Graft Substitutes) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 25: Global: Bone Graft and Substitute (Cell-Based Matrices) Market: Sales Value (in Million US$), 2016 & 2021
Figure 26: Global: Bone Graft and Substitute (Cell-Based Matrices) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 27: Global: Bone Graft and Substitute (Other Material Types) Market: Sales Value (in Million US$), 2016 & 2021
Figure 28: Global: Bone Graft and Substitute (Other Material Types) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 29: Global: Bone Graft and Substitute (Spinal Fusion) Market: Sales Value (in Million US$), 2016 & 2021
Figure 30: Global: Bone Graft and Substitute (Spinal Fusion) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 31: Global: Bone Graft and Substitute (Trauma) Market: Sales Value (in Million US$), 2016 & 2021
Figure 32: Global: Bone Graft and Substitute (Trauma) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 33: Global: Bone Graft and Substitute (Joint Reconstruction) Market: Sales Value (in Million US$), 2016 & 2021
Figure 34: Global: Bone Graft and Substitute (Joint Reconstruction) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 35: Global: Bone Graft and Substitute (Foot and Ankle) Market: Sales Value (in Million US$), 2016 & 2021
Figure 36: Global: Bone Graft and Substitute (Foot and Ankle) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 37: Global: Bone Graft and Substitute (Dental Bone Grafting) Market: Sales Value (in Million US$), 2016 & 2021
Figure 38: Global: Bone Graft and Substitute (Dental Bone Grafting) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 39: Global: Bone Graft and Substitute (Craniomaxillofacial) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 40: Global: Bone Graft and Substitute (Craniomaxillofacial) Market: Sales Value (in Million US$), 2016 & 2021
Figure 41: Global: Bone Graft and Substitute (Other Applications) Market: Sales Value (in Million US$), 2016 & 2021
Figure 42: Global: Bone Graft and Substitute (Other Applications) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 43: Global: Bone Graft and Substitute (Hospitals) Market: Sales Value (in Million US$), 2016 & 2021
Figure 44: Global: Bone Graft and Substitute (Hospitals) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 45: Global: Bone Graft and Substitute (Surgical Centres) Market: Sales Value (in Million US$), 2016 & 2021
Figure 46: Global: Bone Graft and Substitute (Surgical Centres) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 47: Global: Bone Graft and Substitute (Clinics) Market: Sales Value (in Million US$), 2016 & 2021
Figure 48: Global: Bone Graft and Substitute (Clinics) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 49: Global: Bone Graft and Substitute (Other End Users) Market: Sales Value (in Million US$), 2016 & 2021
Figure 50: Global: Bone Graft and Substitute (Other End Users) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 51: North America: Bone Graft and Substitute Market: Sales Value (in Million US$), 2016 & 2021
Figure 52: North America: Bone Graft and Substitute Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 53: Europe: Bone Graft and Substitute Market: Sales Value (in Million US$), 2016 & 2021
Figure 54: Europe: Bone Graft and Substitute Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 55: Asia Pacific: Bone Graft and Substitute Market: Sales Value (in Million US$), 2016 & 2021
Figure 56: Asia Pacific: Bone Graft and Substitute Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 57: Middle East and Africa: Bone Graft and Substitute Market: Sales Value (in Million US$), 2016 & 2021
Figure 58: Middle East and Africa: Bone Graft and Substitute Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 59: Latin America: Bone Graft and Substitute Market: Sales Value (in Million US$), 2016 & 2021
Figure 60: Latin America: Bone Graft and Substitute Market Forecast: Sales Value (in Million US$), 2022-2027


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