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Androgen Insensitivity Syndrome Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

May 2024 | 133 pages | ID: AF0A5FD43C33EN
IMARC Group

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The 7 major androgen insensitivity syndrome markets reached a value of US$ 378.0 Million in 2023. Looking forward, IMARC Group expects the 7MM to reach US$ 633.1 Million by 2034, exhibiting a growth rate (CAGR) of 4.8% during 2024-2034.

The androgen insensitivity syndrome market has been comprehensively analyzed in IMARC's new report titled "Androgen Insensitivity Syndrome Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Androgen insensitivity syndrome (AIS) refers to a rare genetic condition that affects sexual development and is characterized by varying degrees of insensitivity to male sex hormones, or androgens, in individuals with a male chromosomal pattern (XY). This condition causes mutations in the gene that codes for the androgen receptor, leading to the inability of cells to respond to androgens properly. The symptoms of the ailment may vary widely depending on the degree of severity. In complete AIS, individuals suffering from the illness may appear externally female, with underdeveloped or absent male reproductive structures while partial AIS might result in ambiguous genitalia or a mix of both male and female characteristics. Some patients might not even realize they have the condition until puberty, when the absence of menstruation becomes apparent. Diagnosis typically involves a combination of genetic testing to identify mutations in the androgen receptor gene and physical examinations to assess the external and internal genitalia.

The escalating incidences of genetic mutations affecting the androgen receptor's functionality are primarily driving the androgen insensitivity syndrome market. In addition to this, the inflating utilization of efficacious interventions, including hormone therapy, gonadectomy, and psychological support, to manage the condition and alleviate associated challenges, is also creating a positive outlook for the market. Moreover, the widespread adoption of genetic counseling and diagnostic advancements that help in facilitating early detection and personalized management strategies by better understanding and addressing the complex spectrum of AIS is further bolstering the market growth. Apart from this, the rising usage of reconstructive surgeries, which aim to modify or construct physical features and appearance aligned with the patient's identified gender, is acting as another significant growth-inducing factor. Additionally, the emerging popularity of reproductive technologies, like in vitro fertilization with preimplantation genetic testing, that offers prospects for individuals suffering from AIS to achieve parenthood aspirations, is also augmenting the market growth. Furthermore, the increasing demand for genetic editing techniques, notably CRISPR-Cas9 technology, since they work by rectifying or modifying the faulty genes underpinning the condition, thereby improving the treatment outcomes, is expected to drive the androgen insensitivity syndrome market during the forecast period.

IMARC Group's new report provides an exhaustive analysis of the androgen insensitivity syndrome market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for androgen insensitivity syndrome and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the androgen insensitivity syndrome market in any manner.

Time Period of the Study

Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034

Countries Covered

United States
Germany
France
United Kingdom
Italy
Spain
Japan

Analysis Covered Across Each Country

Historical, current, and future epidemiology scenario
Historical, current, and future performance of the androgen insensitivity syndrome market
Historical, current, and future performance of various therapeutic categories in the market
Sales of various drugs across the androgen insensitivity syndrome market
Reimbursement scenario in the market
In-market and pipeline drugs
Competitive Landscape:
This report also provides a detailed analysis of the current androgen insensitivity syndrome marketed drugs and late-stage pipeline drugs.

In-Market Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance
Key Questions Answered in this Report:
Market Insights

How has the androgen insensitivity syndrome market performed so far and how will it perform in the coming years?
What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
What was the country-wise size of the androgen insensitivity syndrome market across the seven major markets in 2023 and what will it look like in 2034?
What is the growth rate of the androgen insensitivity syndrome market across the seven major markets and what will be the expected growth over the next ten years?
What are the key unmet needs in the market?

Epidemiology Insights

What is the number of prevalent cases (2018-2034) of androgen insensitivity syndrome across the seven major markets?
What is the number of prevalent cases (2018-2034) of androgen insensitivity syndrome by age across the seven major markets?
What is the number of prevalent cases (2018-2034) of androgen insensitivity syndrome by gender across the seven major markets?
How many patients are diagnosed (2018-2034) with androgen insensitivity syndrome across the seven major markets?
What is the size of the androgen insensitivity syndrome patient pool (2018-2023) across the seven major markets?
What would be the forecasted patient pool (2024-2034) across the seven major markets?
What are the key factors driving the epidemiological trend of androgen insensitivity syndrome?
What will be the growth rate of patients across the seven major markets?

Androgen Insensitivity Syndrome: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

What are the current marketed drugs and what are their market performance?
What are the key pipeline drugs and how are they expected to perform in the coming years?
How safe are the current marketed drugs and what are their efficacies?
How safe are the late-stage pipeline drugs and what are their efficacies?
What are the current treatment guidelines for androgen insensitivity syndrome drugs across the seven major markets?
Who are the key companies in the market and what are their market shares?
What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the androgen insensitivity syndrome market?
What are the key regulatory events related to the androgen insensitivity syndrome market?
What is the structure of clinical trial landscape by status related to the androgen insensitivity syndrome market?
What is the structure of clinical trial landscape by phase related to the androgen insensitivity syndrome market?
What is the structure of clinical trial landscape by route of administration related to the androgen insensitivity syndrome market?
1 PREFACE

2 SCOPE AND METHODOLOGY

2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
  2.3.1 Primary Sources
  2.3.2 Secondary Sources
2.4 Market Estimation
  2.4.1 Bottom-Up Approach
  2.4.2 Top-Down Approach
2.5 Forecasting Methodology

3 EXECUTIVE SUMMARY

4 ANDROGEN INSENSITIVITY SYNDROME - INTRODUCTION

4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence

5 ANDROGEN INSENSITIVITY SYNDROME - DISEASE OVERVIEW

5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment

6 PATIENT JOURNEY

7 ANDROGEN INSENSITIVITY SYNDROME - EPIDEMIOLOGY AND PATIENT POPULATION

7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
  7.2.1 Epidemiology Scenario (2018-2023)
  7.2.2 Epidemiology Forecast (2024-2034)
  7.2.3 Epidemiology by Age (2018-2034)
  7.2.4 Epidemiology by Gender (2018-2034)
  7.2.5 Diagnosed Cases (2018-2034)
  7.2.6 Patient Pool/Treated Cases (2018-2034)
7.3 Epidemiology Scenario - United States
  7.3.1 Epidemiology Scenario (2018-2023)
  7.3.2 Epidemiology Forecast (2024-2034)
  7.3.3 Epidemiology by Age (2018-2034)
  7.3.4 Epidemiology by Gender (2018-2034)
  7.3.5 Diagnosed Cases (2018-2034)
  7.3.6 Patient Pool/Treated Cases (2018-2034)
7.4 Epidemiology Scenario - Germany
  7.4.1 Epidemiology Scenario (2018-2023)
  7.4.2 Epidemiology Forecast (2024-2034)
  7.4.3 Epidemiology by Age (2018-2034)
  7.4.4 Epidemiology by Gender (2018-2034)
  7.4.5 Diagnosed Cases (2018-2034)
  7.4.6 Patient Pool/Treated Cases (2018-2034)
7.5 Epidemiology Scenario - France
  7.5.1 Epidemiology Scenario (2018-2023)
  7.5.2 Epidemiology Forecast (2024-2034)
  7.5.3 Epidemiology by Age (2018-2034)
  7.5.4 Epidemiology by Gender (2018-2034)
  7.5.5 Diagnosed Cases (2018-2034)
  7.5.6 Patient Pool/Treated Cases (2018-2034)
7.6 Epidemiology Scenario - United Kingdom
  7.6.1 Epidemiology Scenario (2018-2023)
  7.6.2 Epidemiology Forecast (2024-2034)
  7.6.3 Epidemiology by Age (2018-2034)
  7.6.4 Epidemiology by Gender (2018-2034)
  7.6.5 Diagnosed Cases (2018-2034)
  7.6.6 Patient Pool/Treated Cases (2018-2034)
7.7 Epidemiology Scenario - Italy
  7.7.1 Epidemiology Scenario (2018-2023)
  7.7.2 Epidemiology Forecast (2024-2034)
  7.7.3 Epidemiology by Age (2018-2034)
  7.7.4 Epidemiology by Gender (2018-2034)
  7.7.5 Diagnosed Cases (2018-2034)
  7.7.6 Patient Pool/Treated Cases (2018-2034)
7.8 Epidemiology Scenario - Spain
  7.8.1 Epidemiology Scenario (2018-2023)
  7.8.2 Epidemiology Forecast (2024-2034)
  7.8.3 Epidemiology by Age (2018-2034)
  7.8.4 Epidemiology by Gender (2018-2034)
  7.8.5 Diagnosed Cases (2018-2034)
  7.8.6 Patient Pool/Treated Cases (2018-2034)
7.9 Epidemiology Scenario - Japan
  7.9.1 Epidemiology Scenario (2018-2023)
  7.9.2 Epidemiology Forecast (2024-2034)
  7.9.3 Epidemiology by Age (2018-2034)
  7.9.4 Epidemiology by Gender (2018-2034)
  7.9.5 Diagnosed Cases (2018-2034)
  7.9.6 Patient Pool/Treated Cases (2018-2034)

8 ANDROGEN INSENSITIVITY SYNDROME - TREATMENT ALGORITHM, GUIDELINES, AND MEDICAL PRACTICES

8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm

9 ANDROGEN INSENSITIVITY SYNDROME - UNMET NEEDS

10 ANDROGEN INSENSITIVITY SYNDROME - KEY ENDPOINTS OF TREATMENT

11 ANDROGEN INSENSITIVITY SYNDROME - MARKETED PRODUCTS

11.1 List of Androgen Insensitivity Syndrome Marketed Drugs Across the Top 7 Markets
  11.1.1 Drug Name – Company Name
    11.1.1.1 Drug Overview
    11.1.1.2 Mechanism of Action
    11.1.1.3 Regulatory Status
    11.1.1.4 Clinical Trial Results
    11.1.1.5 Sales Across Major Markets
Kindly note that the complete list of marketed drugs has been provided in the report.

12 ANDROGEN INSENSITIVITY SYNDROME - PIPELINE DRUGS

12.1 List of Androgen Insensitivity Syndrome Pipeline Drugs Across the Top 7 Markets
  12.1.1 Drug Name – Company Name
    12.1.1.1 Drug Overview
    12.1.1.2 Mechanism of Action
    12.1.1.3 Clinical Trial Results
    12.1.1.4 Safety and Efficacy
    12.1.1.5 Regulatory Status
Kindly note that the complete list of pipeline drugs has been provided in the report.

13. ANDROGEN INSENSITIVITY SYNDROME - ATTRIBUTE ANALYSIS OF KEY MARKETED AND PIPELINE DRUGS

14. ANDROGEN INSENSITIVITY SYNDROME – CLINICAL TRIAL LANDSCAPE

14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events

15 ANDROGEN INSENSITIVITY SYNDROME - MARKET SCENARIO

15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
  15.2.1 Androgen Insensitivity Syndrome - Market Size
    15.2.1.1 Market Size (2018-2023)
    15.2.1.2 Market Forecast (2024-2034)
  15.2.2 Androgen Insensitivity Syndrome - Market Size by Therapies
    15.2.2.1 Market Size by Therapies (2018-2023)
    15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
  15.3.1 Androgen Insensitivity Syndrome - Market Size
    15.3.1.1 Market Size (2018-2023)
    15.3.1.2 Market Forecast (2024-2034)
  15.3.2 Androgen Insensitivity Syndrome - Market Size by Therapies
    15.3.2.1 Market Size by Therapies (2018-2023)
    15.3.2.2 Market Forecast by Therapies (2024-2034)
  15.3.3 Androgen Insensitivity Syndrome - Access and Reimbursement Overview
15.4 Market Scenario - Germany
  15.4.1 Androgen Insensitivity Syndrome - Market Size
    15.4.1.1 Market Size (2018-2023)
    15.4.1.2 Market Forecast (2024-2034)
  15.4.2 Androgen Insensitivity Syndrome - Market Size by Therapies
    15.4.2.1 Market Size by Therapies (2018-2023)
    15.4.2.2 Market Forecast by Therapies (2024-2034)
  15.4.3 Androgen Insensitivity Syndrome - Access and Reimbursement Overview
15.5 Market Scenario - France
  15.5.1 Androgen Insensitivity Syndrome - Market Size
    15.5.1.1 Market Size (2018-2023)
    15.5.1.2 Market Forecast (2024-2034)
  15.5.2 Androgen Insensitivity Syndrome - Market Size by Therapies
    15.5.2.1 Market Size by Therapies (2018-2023)
    15.5.2.2 Market Forecast by Therapies (2024-2034)
  15.5.3 Androgen Insensitivity Syndrome - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
  15.6.1 Androgen Insensitivity Syndrome - Market Size
    15.6.1.1 Market Size (2018-2023)
    15.6.1.2 Market Forecast (2024-2034)
  15.6.2 Androgen Insensitivity Syndrome - Market Size by Therapies
    15.6.2.1 Market Size by Therapies (2018-2023)
    15.6.2.2 Market Forecast by Therapies (2024-2034)
  15.6.3 Androgen Insensitivity Syndrome - Access and Reimbursement Overview
15.7 Market Scenario - Italy
  15.7.1 Androgen Insensitivity Syndrome - Market Size
    15.7.1.1 Market Size (2018-2023)
    15.7.1.2 Market Forecast (2024-2034)
  15.7.2 Androgen Insensitivity Syndrome - Market Size by Therapies
    15.7.2.1 Market Size by Therapies (2018-2023)
    15.7.2.2 Market Forecast by Therapies (2024-2034)
  15.7.3 Androgen Insensitivity Syndrome - Access and Reimbursement Overview
15.8 Market Scenario - Spain
  15.8.1 Androgen Insensitivity Syndrome - Market Size
    15.8.1.1 Market Size (2018-2023)
    15.8.1.2 Market Forecast (2024-2034)
  15.8.2 Androgen Insensitivity Syndrome - Market Size by Therapies
    15.8.2.1 Market Size by Therapies (2018-2023)
    15.8.2.2 Market Forecast by Therapies (2024-2034)
  15.8.3 Androgen Insensitivity Syndrome - Access and Reimbursement Overview
15.9 Market Scenario - Japan
  15.9.1 Androgen Insensitivity Syndrome - Market Size
    15.9.1.1 Market Size (2018-2023)
    15.9.1.2 Market Forecast (2024-2034)
  15.9.2 Androgen Insensitivity Syndrome - Market Size by Therapies
    15.9.2.1 Market Size by Therapies (2018-2023)
    15.9.2.2 Market Forecast by Therapies (2024-2034)
  15.9.3 Androgen Insensitivity Syndrome - Access and Reimbursement Overview

16 ANDROGEN INSENSITIVITY SYNDROME - RECENT EVENTS AND INPUTS FROM KEY OPINION LEADERS

17 ANDROGEN INSENSITIVITY SYNDROME MARKET - SWOT ANALYSIS

17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats

18 ANDROGEN INSENSITIVITY SYNDROME MARKET – STRATEGIC RECOMMENDATIONS

19 APPENDIX


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