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Andersen Disease Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

May 2024 | 130 pages | ID: AA5497249EE7EN
IMARC Group

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The 7 major Andersen disease markets reached a value of US$ 1.1 Billion in 2023. Looking forward, IMARC Group expects the 7MM to reach US$ 1.8 Billion by 2034, exhibiting a growth rate (CAGR) of 4.76% during 2024-2034.

The Andersen disease market has been comprehensively analyzed in IMARC's new report titled "Andersen Disease Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Andersen disease is a rare inherited metabolic disorder that affects the body's ability to process glycogen, the primary storage form of glucose. This ailment is caused by mutations in the GBE1 gene, leading to a deficiency of the glycogen branching enzyme. The symptoms of the illness can vary widely and typically manifest in early childhood. Infants suffering from this disease may experience failure to thrive, an enlarged liver, and potentially life-threatening hepatic and heart complications. As the ailment progresses, it might lead to muscle weakness, delayed motor development, and skeletal abnormalities. The diagnosis of Andersen disease involves a combination of clinical evaluations, family history assessments, and specialized laboratory tests. A liver biopsy is often performed to examine the glycogen accumulation and branching patterns, confirming the diagnosis. The healthcare provider may also conduct genetic testing to identify specific mutations in the genes, thereby validating the presence of the disorder and aiding in assessing the risk for affected family members.

The rising cases of mutations in the GBE1 gene, which disrupt the normal glycogen metabolism process, leading to the overgrowth of glycogen molecules without proper branching, thereby affecting organ function, are primarily driving the Andersen disease market. In addition to this, the inflating utilization of effective medications, such as enzyme replacement therapies and supportive care, that are aimed at managing the symptoms and complications of the ailment is fostering a positive outlook for the market. Moreover, the widespread adoption of physical and occupational therapies, since they aid in strengthening muscles, improving coordination, and encouraging gross motor skills in individuals suffering from the illness, is further bolstering the market growth. These therapeutic interventions mainly contribute to enhancing mobility and the overall quality of life for patients. Apart from this, the growing awareness and understanding of Andersen disease among healthcare professionals and the public, leading to earlier diagnosis and better management of the condition, is acting as another significant growth-inducing factor. Additionally, the emerging popularity of innovative approaches, like gene therapy, which involves introducing functional genetic material into cells to correct or replace the mutated GBE1 gene responsible for the disorder, is expected to drive the Andersen disease market during the forecast period.

IMARC Group's new report provides an exhaustive analysis of the Andersen disease market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for Andersen disease and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the Andersen disease market in any manner.

Time Period of the Study

Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034

Countries Covered

United States
Germany
France
United Kingdom
Italy
Spain
Japan

Analysis Covered Across Each Country

Historical, current, and future epidemiology scenario
Historical, current, and future performance of the Andersen disease market
Historical, current, and future performance of various therapeutic categories in the market
Sales of various drugs across the Andersen disease market
Reimbursement scenario in the market
In-market and pipeline drugs
Competitive Landscape:
This report also provides a detailed analysis of the current Andersen disease marketed drugs and late-stage pipeline drugs.

In-Market Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance
Key Questions Answered in this Report:
Market Insights

How has the Andersen disease market performed so far and how will it perform in the coming years?
What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
What was the country-wise size of the Andersen disease market across the seven major markets in 2023 and what will it look like in 2034?
What is the growth rate of the Andersen disease market across the seven major markets and what will be the expected growth over the next ten years?
What are the key unmet needs in the market?

Epidemiology Insights

What is the number of prevalent cases (2018-2034) of Andersen disease across the seven major markets?
What is the number of prevalent cases (2018-2034) of Andersen disease by age across the seven major markets?
What is the number of prevalent cases (2018-2034) of Andersen disease by gender across the seven major markets?
How many patients are diagnosed (2018-2034) with Andersen disease across the seven major markets?
What is the size of the Andersen disease patient pool (2018-2023) across the seven major markets?
What would be the forecasted patient pool (2024-2034) across the seven major markets?
What are the key factors driving the epidemiological trend of Andersen disease?
What will be the growth rate of patients across the seven major markets?

Andersen Disease: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

What are the current marketed drugs and what are their market performance?
What are the key pipeline drugs and how are they expected to perform in the coming years?
How safe are the current marketed drugs and what are their efficacies?
How safe are the late-stage pipeline drugs and what are their efficacies?
What are the current treatment guidelines for Andersen disease drugs across the seven major markets?
Who are the key companies in the market and what are their market shares?
What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the Andersen disease market?
What are the key regulatory events related to the Andersen disease market?
What is the structure of clinical trial landscape by status related to the Andersen disease market?
What is the structure of clinical trial landscape by phase related to the Andersen disease market?
What is the structure of clinical trial landscape by route of administration related to the Andersen disease market?
1 PREFACE

2 SCOPE AND METHODOLOGY

2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
  2.3.1 Primary Sources
  2.3.2 Secondary Sources
2.4 Market Estimation
  2.4.1 Bottom-Up Approach
  2.4.2 Top-Down Approach
2.5 Forecasting Methodology

3 EXECUTIVE SUMMARY

4 ANDERSEN DISEASE - INTRODUCTION

4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence

5 ANDERSEN DISEASE - DISEASE OVERVIEW

5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment

6 PATIENT JOURNEY

7 ANDERSEN DISEASE - EPIDEMIOLOGY AND PATIENT POPULATION

7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
  7.2.1 Epidemiology Scenario (2018-2023)
  7.2.2 Epidemiology Forecast (2024-2034)
  7.2.3 Epidemiology by Age (2018-2034)
  7.2.4 Epidemiology by Gender (2018-2034)
  7.2.5 Diagnosed Cases (2018-2034)
  7.2.6 Patient Pool/Treated Cases (2018-2034)
7.3 Epidemiology Scenario - United States
  7.3.1 Epidemiology Scenario (2018-2023)
  7.3.2 Epidemiology Forecast (2024-2034)
  7.3.3 Epidemiology by Age (2018-2034)
  7.3.4 Epidemiology by Gender (2018-2034)
  7.3.5 Diagnosed Cases (2018-2034)
  7.3.6 Patient Pool/Treated Cases (2018-2034)
7.4 Epidemiology Scenario - Germany
  7.4.1 Epidemiology Scenario (2018-2023)
  7.4.2 Epidemiology Forecast (2024-2034)
  7.4.3 Epidemiology by Age (2018-2034)
  7.4.4 Epidemiology by Gender (2018-2034)
  7.4.5 Diagnosed Cases (2018-2034)
  7.4.6 Patient Pool/Treated Cases (2018-2034)
7.5 Epidemiology Scenario - France
  7.5.1 Epidemiology Scenario (2018-2023)
  7.5.2 Epidemiology Forecast (2024-2034)
  7.5.3 Epidemiology by Age (2018-2034)
  7.5.4 Epidemiology by Gender (2018-2034)
  7.5.5 Diagnosed Cases (2018-2034)
  7.5.6 Patient Pool/Treated Cases (2018-2034)
7.6 Epidemiology Scenario - United Kingdom
  7.6.1 Epidemiology Scenario (2018-2023)
  7.6.2 Epidemiology Forecast (2024-2034)
  7.6.3 Epidemiology by Age (2018-2034)
  7.6.4 Epidemiology by Gender (2018-2034)
  7.6.5 Diagnosed Cases (2018-2034)
  7.6.6 Patient Pool/Treated Cases (2018-2034)
7.7 Epidemiology Scenario - Italy
  7.7.1 Epidemiology Scenario (2018-2023)
  7.7.2 Epidemiology Forecast (2024-2034)
  7.7.3 Epidemiology by Age (2018-2034)
  7.7.4 Epidemiology by Gender (2018-2034)
  7.7.5 Diagnosed Cases (2018-2034)
  7.7.6 Patient Pool/Treated Cases (2018-2034)
7.8 Epidemiology Scenario - Spain
  7.8.1 Epidemiology Scenario (2018-2023)
  7.8.2 Epidemiology Forecast (2024-2034)
  7.8.3 Epidemiology by Age (2018-2034)
  7.8.4 Epidemiology by Gender (2018-2034)
  7.8.5 Diagnosed Cases (2018-2034)
  7.8.6 Patient Pool/Treated Cases (2018-2034)
7.9 Epidemiology Scenario - Japan
  7.9.1 Epidemiology Scenario (2018-2023)
  7.9.2 Epidemiology Forecast (2024-2034)
  7.9.3 Epidemiology by Age (2018-2034)
  7.9.4 Epidemiology by Gender (2018-2034)
  7.9.5 Diagnosed Cases (2018-2034)
  7.9.6 Patient Pool/Treated Cases (2018-2034)

8 ANDERSEN DISEASE - TREATMENT ALGORITHM, GUIDELINES, AND MEDICAL PRACTICES

8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm

9 ANDERSEN DISEASE - UNMET NEEDS

10 ANDERSEN DISEASE - KEY ENDPOINTS OF TREATMENT

11 ANDERSEN DISEASE - MARKETED PRODUCTS

11.1 List of Andersen Disease Marketed Drugs Across the Top 7 Markets
  11.1.1 Drug Name – Company Name
    11.1.1.1 Drug Overview
    11.1.1.2 Mechanism of Action
    11.1.1.3 Regulatory Status
    11.1.1.4 Clinical Trial Results
    11.1.1.5 Sales Across Major Markets
Kindly note that the complete list of marketed drugs has been provided in the report.

12 ANDERSEN DISEASE - PIPELINE DRUGS

12.1 List of Andersen Disease Pipeline Drugs Across the Top 7 Markets
  12.1.1 Drug Name – Company Name
    12.1.1.1 Drug Overview
    12.1.1.2 Mechanism of Action
    12.1.1.3 Clinical Trial Results
    12.1.1.4 Safety and Efficacy
    12.1.1.5 Regulatory Status
Kindly note that the complete list of pipeline drugs has been provided in the report.

13. ANDERSEN DISEASE - ATTRIBUTE ANALYSIS OF KEY MARKETED AND PIPELINE DRUGS

14. ANDERSEN DISEASE – CLINICAL TRIAL LANDSCAPE

14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events

15 ANDERSEN DISEASE - MARKET SCENARIO

15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
  15.2.1 Andersen Disease - Market Size
    15.2.1.1 Market Size (2018-2023)
    15.2.1.2 Market Forecast (2024-2034)
  15.2.2 Andersen Disease - Market Size by Therapies
    15.2.2.1 Market Size by Therapies (2018-2023)
    15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
  15.3.1 Andersen Disease - Market Size
    15.3.1.1 Market Size (2018-2023)
    15.3.1.2 Market Forecast (2024-2034)
  15.3.2 Andersen Disease - Market Size by Therapies
    15.3.2.1 Market Size by Therapies (2018-2023)
    15.3.2.2 Market Forecast by Therapies (2024-2034)
  15.3.3 Andersen Disease - Access and Reimbursement Overview
15.4 Market Scenario - Germany
  15.4.1 Andersen Disease - Market Size
    15.4.1.1 Market Size (2018-2023)
    15.4.1.2 Market Forecast (2024-2034)
  15.4.2 Andersen Disease - Market Size by Therapies
    15.4.2.1 Market Size by Therapies (2018-2023)
    15.4.2.2 Market Forecast by Therapies (2024-2034)
  15.4.3 Andersen Disease - Access and Reimbursement Overview
15.5 Market Scenario - France
  15.5.1 Andersen Disease - Market Size
    15.5.1.1 Market Size (2018-2023)
    15.5.1.2 Market Forecast (2024-2034)
  15.5.2 Andersen Disease - Market Size by Therapies
    15.5.2.1 Market Size by Therapies (2018-2023)
    15.5.2.2 Market Forecast by Therapies (2024-2034)
  15.5.3 Andersen Disease - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
  15.6.1 Andersen Disease - Market Size
    15.6.1.1 Market Size (2018-2023)
    15.6.1.2 Market Forecast (2024-2034)
  15.6.2 Andersen Disease - Market Size by Therapies
    15.6.2.1 Market Size by Therapies (2018-2023
    15.6.2.2 Market Forecast by Therapies (2024-2034)
  15.6.3 Andersen Disease - Access and Reimbursement Overview
15.7 Market Scenario - Italy
  15.7.1 Andersen Disease - Market Size
    15.7.1.1 Market Size (2018-2023)
    15.7.1.2 Market Forecast (2024-2034)
  15.7.2 Andersen Disease - Market Size by Therapies
    15.7.2.1 Market Size by Therapies (2018-2023)
    15.7.2.2 Market Forecast by Therapies (2024-2034)
  15.7.3 Andersen Disease - Access and Reimbursement Overview
15.8 Market Scenario - Spain
  15.8.1 Andersen Disease - Market Size
    15.8.1.1 Market Size (2018-2023)
    15.8.1.2 Market Forecast (2024-2034)
  15.8.2 Andersen Disease - Market Size by Therapies
    15.8.2.1 Market Size by Therapies (2018-2023)
    15.8.2.2 Market Forecast by Therapies (2024-2034)
  15.8.3 Andersen Disease - Access and Reimbursement Overview
15.9 Market Scenario - Japan
  15.9.1 Andersen Disease - Market Size
    15.9.1.1 Market Size (2018-2023)
    15.9.1.2 Market Forecast (2024-2034)
  15.9.2 Andersen Disease - Market Size by Therapies
    15.9.2.1 Market Size by Therapies (2018-2023)
    15.9.2.2 Market Forecast by Therapies (2024-2034)
  15.9.3 Andersen Disease - Access and Reimbursement Overview

16 ANDERSEN DISEASE - RECENT EVENTS AND INPUTS FROM KEY OPINION LEADERS

17 ANDERSEN DISEASE MARKET - SWOT ANALYSIS

17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats

18 ANDERSEN DISEASE MARKET – STRATEGIC RECOMMENDATIONS

19 APPENDIX


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