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Advanced Liver Cancer Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

May 2024 | 137 pages | ID: A107DB5BD0D1EN
IMARC Group

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The 7 major advanced liver cancer markets reached a value of US$ 2.0 Billion in 2023. Looking forward, IMARC Group expects the 7MM to reach US$ 9.6 Billion by 2034, exhibiting a growth rate (CAGR) of 15.36% during 2024-2034.

The advanced liver cancer market has been comprehensively analyzed in IMARC's new report titled "Advanced Liver Cancer Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Advanced liver cancer, also known as stage 4 or metastatic liver cancer, refers to a condition where cancerous cells have spread from the liver to other parts of the body, such as the lungs, bones, blood vessels, and lymph nodes. The symptoms of this ailment include a feeling of fullness, fatigue, unintentional weight loss, abdominal pain or swelling, yellowing of the skin and eyes, loss of appetite, persistent coughing, nausea, vomiting, general weakness, etc. Individuals suffering from the disease may also experience impaired liver function, which can further lead to cognitive changes, confusion, memory problems, and even coma in severe cases. The diagnosis of this illness requires a combination of the patient's underlying indications, a detailed medical history, and various blood workups. The healthcare professional may perform numerous diagnostic procedures, like positron emission tomography (PET) scans, magnetic resonance imaging, ultrasounds, etc., to obtain comprehensive pictures of the affected site and determine the exact size, location, and extent of the tumor. Additionally, liver biopsy and histologic examination are also recommended to confirm a diagnosis among patients.

The increasing prevalence of genetic conditions, which predispose an individual to liver damage on account of gene mutations, is primarily driving the advanced liver cancer market. In addition to this, the rising incidences of several associated risk factors, including chronic infection with the hepatitis B or C virus, excessive alcohol consumption, exposure to aflatoxins (mainly through contaminated food), etc., are also bolstering the market growth. Furthermore, the escalating adoption of immune checkpoint inhibitors, such as atezolizumab and bevacizumab, that help to stimulate the body's defense mechanism to recognize and attack cancerous cells is acting as another significant growth-inducing factor. Additionally, the emerging popularity of radiofrequency ablation therapy, owing to its numerous benefits, like a faster recovery time and shorter hospital stay, is also creating a positive outlook for the market. Moreover, the widespread demand for transarterial chemoembolization for the treatment of this illness, since it works by injecting chemotherapy drugs directly into the hepatic artery, thereby blocking the supply of nutrients to the tumor cells, is expected to drive the advanced liver cancer market in the coming years.

IMARC Group's new report provides an exhaustive analysis of the advanced liver cancer market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for advanced liver cancer and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the advanced liver cancer market in any manner.

Time Period of the Study

Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034

Countries Covered

United States
Germany
France
United Kingdom
Italy
Spain
Japan

Analysis Covered Across Each Country

Historical, current, and future epidemiology scenario
Historical, current, and future performance of the advanced liver cancer market
Historical, current, and future performance of various therapeutic categories in the market
Sales of various drugs across the advanced liver cancer market
Reimbursement scenario in the market
In-market and pipeline drugs
Competitive Landscape:
This report also provides a detailed analysis of the current advanced liver cancer marketed drugs and late-stage pipeline drugs.

In-Market Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.

Key Questions Answered in this Report:
Market Insights

How has the advanced liver cancer market performed so far and how will it perform in the coming years?
What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
What was the country-wise size of the advanced liver cancer market across the seven major markets in 2023 and what will it look like in 2034?
What is the growth rate of the advanced liver cancer market across the seven major markets and what will be the expected growth over the next ten years?
What are the key unmet needs in the market?

Epidemiology Insights

What is the number of prevalent cases (2018-2034) of advanced liver cancer across the seven major markets?
What is the number of prevalent cases (2018-2034) of advanced liver cancer by age across the seven major markets?
What is the number of prevalent cases (2018-2034) of advanced liver cancer by gender across the seven major markets?
How many patients are diagnosed (2018-2034) with advanced liver cancer across the seven major markets?
What is the size of the advanced liver cancer patient pool (2018-2023) across the seven major markets?
What would be the forecasted patient pool (2024-2034) across the seven major markets?
What are the key factors driving the epidemiological trend of advanced liver cancer?
What will be the growth rate of patients across the seven major markets?

Advanced Liver Cancer: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

What are the current marketed drugs and what are their market performance?
What are the key pipeline drugs and how are they expected to perform in the coming years?
How safe are the current marketed drugs and what are their efficacies?
How safe are the late-stage pipeline drugs and what are their efficacies?
What are the current treatment guidelines for advanced liver cancer drugs across the seven major markets?
Who are the key companies in the market and what are their market shares?
What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the advanced liver cancer market?
What are the key regulatory events related to the advanced liver cancer market?
What is the structure of clinical trial landscape by status related to the advanced liver cancer market?
What is the structure of clinical trial landscape by phase related to the advanced liver cancer market?
What is the structure of clinical trial landscape by route of administration related to the advanced liver cancer market?
?1 Preface

2 SCOPE AND METHODOLOGY

2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
  2.3.1 Primary Sources
  2.3.2 Secondary Sources
2.4 Market Estimation
  2.4.1 Bottom-Up Approach
  2.4.2 Top-Down Approach
2.5 Forecasting Methodology

3 EXECUTIVE SUMMARY

4 ADVANCED LIVER CANCER - INTRODUCTION

4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence

5 ADVANCED LIVER CANCER - DISEASE OVERVIEW

5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment

6 PATIENT JOURNEY

7 ADVANCED LIVER CANCER - EPIDEMIOLOGY AND PATIENT POPULATION

7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
  7.2.1 Epidemiology Scenario (2018-2023)
  7.2.2 Epidemiology Forecast (2024-2034)
  7.2.3 Epidemiology by Age (2018-2034)
  7.2.4 Epidemiology by Gender (2018-2034)
  7.2.5 Diagnosed Cases (2018-2034)
  7.2.6 Patient Pool/Treated Cases (2018-2034)
7.3 Epidemiology Scenario - United States
  7.3.1 Epidemiology Scenario (2018-2023)
  7.3.2 Epidemiology Forecast (2024-2034)
  7.3.3 Epidemiology by Age (2018-2034)
  7.3.4 Epidemiology by Gender (2018-2034)
  7.3.5 Diagnosed Cases (2018-2034)
  7.3.6 Patient Pool/Treated Cases (2018-2034)
7.4 Epidemiology Scenario - Germany
  7.4.1 Epidemiology Scenario (2018-2023)
  7.4.2 Epidemiology Forecast (2024-2034)
  7.4.3 Epidemiology by Age (2018-2034)
  7.4.4 Epidemiology by Gender (2018-2034)
  7.4.5 Diagnosed Cases (2018-2034)
  7.4.6 Patient Pool/Treated Cases (2018-2034)
7.5 Epidemiology Scenario - France
  7.5.1 Epidemiology Scenario (2018-2023)
  7.5.2 Epidemiology Forecast (2024-2034)
  7.5.3 Epidemiology by Age (2018-2034)
  7.5.4 Epidemiology by Gender (2018-2034)
  7.5.5 Diagnosed Cases (2018-2034)
  7.5.6 Patient Pool/Treated Cases (2018-2034)
7.6 Epidemiology Scenario - United Kingdom
  7.6.1 Epidemiology Scenario (2018-2023)
  7.6.2 Epidemiology Forecast (2024-2034)
  7.6.3 Epidemiology by Age (2018-2034)
  7.6.4 Epidemiology by Gender (2018-2034)
  7.6.5 Diagnosed Cases (2018-2034)
  7.6.6 Patient Pool/Treated Cases (2018-2034)
7.7 Epidemiology Scenario - Italy
  7.7.1 Epidemiology Scenario (2018-2023)
  7.7.2 Epidemiology Forecast (2024-2034)
  7.7.3 Epidemiology by Age (2018-2034)
  7.7.4 Epidemiology by Gender (2018-2034)
  7.7.5 Diagnosed Cases (2018-2034)
  7.7.6 Patient Pool/Treated Cases (2018-2034)
7.8 Epidemiology Scenario - Spain
  7.8.1 Epidemiology Scenario (2018-2023)
  7.8.2 Epidemiology Forecast (2024-2034)
  7.8.3 Epidemiology by Age (2018-2034)
  7.8.4 Epidemiology by Gender (2018-2034)
  7.8.5 Diagnosed Cases (2018-2034)
  7.8.6 Patient Pool/Treated Cases (2018-2034)
7.9 Epidemiology Scenario - Japan
  7.9.1 Epidemiology Scenario (2018-2023)
  7.9.2 Epidemiology Forecast (2024-2034)
  7.9.3 Epidemiology by Age (2018-2034)
  7.9.4 Epidemiology by Gender (2018-2034)
  7.9.5 Diagnosed Cases (2018-2034)
  7.9.6 Patient Pool/Treated Cases (2018-2034)

8 ADVANCED LIVER CANCER - TREATMENT ALGORITHM, GUIDELINES, AND MEDICAL PRACTICES

8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm

9 ADVANCED LIVER CANCER - UNMET NEEDS

10 ADVANCED LIVER CANCER - KEY ENDPOINTS OF TREATMENT

11 ADVANCED LIVER CANCER - MARKETED PRODUCTS

11.1 List of Advanced Liver Cancer Marketed Drugs Across the Top 7 Markets
  11.1.1 Cyramza (Ramucirumab) - Eli Lilly and Company
    11.1.1.1 Drug Overview
    11.1.1.2 Mechanism of Action
    11.1.1.3 Regulatory Status
    11.1.1.4 Clinical Trial Results
    11.1.1.5 Sales Across Major Markets
  11.1.2 Tecentriq (Atezolizumab) - Genentech
    11.1.2.1 Drug Overview
    11.1.2.2 Mechanism of Action
    11.1.2.3 Regulatory Status
    11.1.2.4 Clinical Trial Results
    11.1.2.5 Sales Across Major Markets
  11.1.3 Yervoy (Ipilimumab) - Bristol Myers Squibb
    11.1.3.1 Drug Overview
    11.1.3.2 Mechanism of Action
    11.1.3.3 Regulatory Status
    11.1.3.4 Clinical Trial Results
    11.1.3.5 Sales Across Major Markets
  11.1.4 Opdivo (Nivolumab) - Bristol-Myers Squibb/Ono Pharmaceuticals
    11.1.4.1 Drug Overview
    11.1.4.2 Mechanism of Action
    11.1.4.3 Regulatory Status
    11.1.4.4 Clinical Trial Results
    11.1.4.5 Sales Across Major Markets
  11.1.5 Keytruda (Pembrolizumab) - Merck & Co
    11.1.5.1 Drug Overview
    11.1.5.2 Mechanism of Action
    11.1.5.3 Regulatory Status
    11.1.5.4 Clinical Trial Results
    11.1.5.5 Sales Across Major Markets
Kindly note that the above only represents a partial list of marketed drugs, and the complete list has been provided in the report.

12 ADVANCED LIVER CANCER - PIPELINE DRUGS

12.1 List of Advanced Liver Cancer Pipeline Drugs Across the Top 7 Markets
  12.1.1 Q702 - Qurient Co., Ltd.
    12.1.1.1 Drug Overview
    12.1.1.2 Mechanism of Action
    12.1.1.3 Clinical Trial Results
    12.1.1.4 Safety and Efficacy
    12.1.1.5 Regulatory Status
  12.1.2 MTL CEBPA - Mina Alpha Limited
    12.1.2.1 Drug Overview
    12.1.2.2 Mechanism of Action
    12.1.2.3 Clinical Trial Results
    12.1.2.4 Safety and Efficacy
    12.1.2.5 Regulatory Status
  12.1.3 TEC-001 - Teclison
    12.1.3.1 Drug Overview
    12.1.3.2 Mechanism of Action
    12.1.3.3 Clinical Trial Results
    12.1.3.4 Safety and Efficacy
    12.1.3.5 Regulatory Status
  12.1.4 TSR022 - AnaptysBio/Glaxo SmithKline
    12.1.4.1 Drug Overview
    12.1.4.2 Mechanism of Action
    12.1.4.3 Clinical Trial Results
    12.1.4.4 Safety and Efficacy
    12.1.4.5 Regulatory Status
  12.1.5 ET1402L1-CART - Eureka Therapeutics
    12.1.5.1 Drug Overview
    12.1.5.2 Mechanism of Action
    12.1.5.3 Clinical Trial Results
    12.1.5.4 Safety and Efficacy
    12.1.5.5 Regulatory Status
Kindly note that the above only represents a partial list of pipeline drugs, and the complete list has been provided in the report.

13. ADVANCED LIVER CANCER - ATTRIBUTE ANALYSIS OF KEY MARKETED AND PIPELINE DRUGS

14. ADVANCED LIVER CANCER – CLINICAL TRIAL LANDSCAPE

14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events

15 ADVANCED LIVER CANCER - MARKET SCENARIO

15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
  15.2.1 Advanced Liver Cancer - Market Size
    15.2.1.1 Market Size (2018-2023)
    15.2.1.2 Market Forecast (2024-2034)
  15.2.2 Advanced Liver Cancer - Market Size by Therapies
    15.2.2.1 Market Size by Therapies (2018-2023)
    15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
  15.3.1 Advanced Liver Cancer - Market Size
    15.3.1.1 Market Size (2018-2023)
    15.3.1.2 Market Forecast (2024-2034)
  15.3.2 Advanced Liver Cancer - Market Size by Therapies
    15.3.2.1 Market Size by Therapies (2018-2023)
    15.3.2.2 Market Forecast by Therapies (2024-2034)
  15.3.3 Advanced Liver Cancer - Access and Reimbursement Overview
15.4 Market Scenario - Germany
  15.4.1 Advanced Liver Cancer - Market Size
    15.4.1.1 Market Size (2018-2023)
    15.4.1.2 Market Forecast (2024-2034)
  15.4.2 Advanced Liver Cancer - Market Size by Therapies
    15.4.2.1 Market Size by Therapies (2018-2023)
    15.4.2.2 Market Forecast by Therapies (2024-2034)
  15.4.3 Advanced Liver Cancer - Access and Reimbursement Overview
15.5 Market Scenario - France
  15.5.1 Advanced Liver Cancer - Market Size
    15.5.1.1 Market Size (2018-2023)
    15.5.1.2 Market Forecast (2024-2034)
  15.5.2 Advanced Liver Cancer - Market Size by Therapies
    15.5.2.1 Market Size by Therapies (2018-2023)
    15.5.2.2 Market Forecast by Therapies (2024-2034)
  15.5.3 Advanced Liver Cancer - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
  15.6.1 Advanced Liver Cancer - Market Size
    15.6.1.1 Market Size (2018-2023)
    15.6.1.2 Market Forecast (2024-2034)
  15.6.2 Advanced Liver Cancer - Market Size by Therapies
    15.6.2.1 Market Size by Therapies (2018-2023)
    15.6.2.2 Market Forecast by Therapies (2024-2034)
  15.6.3 Advanced Liver Cancer - Access and Reimbursement Overview
15.7 Market Scenario - Italy
  15.7.1 Advanced Liver Cancer - Market Size
    15.7.1.1 Market Size (2018-2023)
    15.7.1.2 Market Forecast (2024-2034)
  15.7.2 Advanced Liver Cancer - Market Size by Therapies
    15.7.2.1 Market Size by Therapies (2018-2023)
    15.7.2.2 Market Forecast by Therapies (2024-2034)
  15.7.3 Advanced Liver Cancer - Access and Reimbursement Overview
15.8 Market Scenario - Spain
  15.8.1 Advanced Liver Cancer - Market Size
    15.8.1.1 Market Size (2018-2023)
    15.8.1.2 Market Forecast (2024-2034)
  15.8.2 Advanced Liver Cancer - Market Size by Therapies
    15.8.2.1 Market Size by Therapies (2018-2023)
    15.8.2.2 Market Forecast by Therapies (2024-2034)
  15.8.3 Advanced Liver Cancer - Access and Reimbursement Overview
15.9 Market Scenario - Japan
  15.9.1 Advanced Liver Cancer - Market Size
    15.9.1.1 Market Size (2018-2023)
    15.9.1.2 Market Forecast (2024-2034)
  15.9.2 Advanced Liver Cancer - Market Size by Therapies
    15.9.2.1 Market Size by Therapies (2018-2023)
    15.9.2.2 Market Forecast by Therapies (2024-2034)
  15.9.3 Advanced Liver Cancer - Access and Reimbursement Overview

16 ADVANCED LIVER CANCER - RECENT EVENTS AND INPUTS FROM KEY OPINION LEADERS

17 ADVANCED LIVER CANCER MARKET - SWOT ANALYSIS

17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats

18 ADVANCED LIVER CANCER MARKET – STRATEGIC RECOMMENDATIONS

19 APPENDIX


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