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Acute Kidney Injury Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

May 2024 | 140 pages | ID: A4AF3E9A19C5EN
IMARC Group

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The 7 major acute kidney injury markets reached a value of US$ 5,766.5 Million in 2023. Looking forward, IMARC Group expects the 7MM to reach US$ 9,904.0 Million by 2034, exhibiting a growth rate (CAGR) of 5.04% during 2024-2034.

The acute kidney injury market has been comprehensively analyzed in IMARC’s new report titled “Acute Kidney Injury Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034”. Acute kidney injury (AKI) is a sudden and often reversible decline in kidney function that typically occurs over a short period of time, usually within hours to days. It is characterized by an increase in levels of waste products in the blood, fluid overload, and electrolyte imbalances. Acute kidney injury can be caused due to several factors, such as reduced blood flow to the kidneys, severe infections, blockage of the urinary tract, prolonged use of certain medications, etc. Some common symptoms of the ailment include swelling in the legs, ankles, or feet, decreased urine output, shortness of breath, chest pain, seizures, muscle twitching, etc. Acute kidney injury is diagnosed using a combination of physical examination and lab tests. Generally, blood tests are utilized to assess creatinine and blood urea nitrogen (BUN) levels. Additionally, urine tests may be carried out to measure the amount of protein and red and white blood cells in the urine, which can indicate kidney damage. Various imaging tests, such as ultrasound, CT scan, and MRI, can also be used to visualize the kidneys and urinary tract.

The rising prevalence of certain medical conditions, such as sepsis and lupus nephritis, along with the increasing cases of direct kidney injury from drugs or toxins are primarily driving the global acute kidney injury market. In addition to this, the escalating utilization of several medications, including angiotensin-converting enzyme inhibitors (ACE inhibitors) and angiotensin receptor blockers (ARBs), to manage blood pressure and reduce the risk of further kidney damage is also bolstering the market growth. Besides this, the growing awareness regarding the importance of early detection and diagnosis of AKI, as prompt intervention can lower the chances of severe complications and improve patient outcomes, is further propelling the global market. Additionally, several key players are making extensive investments in realizing the potential of regenerative medicine and stem cell therapy for treating AKI since they show promise in restoring normal kidney function and reducing the need for dialysis. This, in turn, is also bolstering the market growth. Apart from this, the ongoing advancements in the field of nephrology, which are further augmenting the development of new drugs, devices, and diagnostic tools for AKI, are expected to drive the global acute kidney injury market in the coming years.

IMARC Group’s new report provides an exhaustive analysis of the acute kidney injury market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report, the United States has the largest patient pool for acute kidney injury and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the acute kidney injury market in any manner.

Time Period of the Study

Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034

Countries Covered

United States
Germany
France
United Kingdom
Italy
Spain
Japan

Analysis Covered Across Each Country

Historical, current, and future epidemiology scenario
Historical, current, and future performance of the acute kidney injury market
Historical, current, and future performance of various therapeutic categories in the market
Sales of various drugs across the acute kidney injury market
Reimbursement scenario in the market
In-market and pipeline drugs
Competitive Landscape:
This report also provides a detailed analysis of the current acute kidney injury marketed drugs and late-stage pipeline drugs.

In-Market Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.

Key Questions Answered in this Report:
Market Insights

How has the acute kidney injury market performed so far and how will it perform in the coming years?
What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
What was the country-wise size of the acute kidney injury market across the seven major markets in 2023 and what will it look like in 2034?
What is the growth rate of the acute kidney injury market across the seven major markets and what will be the expected growth over the next ten years?
What are the key unmet needs in the market?

Epidemiology Insights

What is the number of prevalent cases (?2018-2034?) of acute kidney injury across the seven major markets?
What is the number of prevalent cases (?2018-2034?) of acute kidney injury by age across the seven major markets?
What is the number of prevalent cases (?2018-2034?) of acute kidney injury by gender across the seven major markets?
How many patients are diagnosed (?2018-2034?) with acute kidney injury across the seven major markets?
What is the size of the acute kidney injury patient pool (2018-2023) across the seven major markets?
What would be the forecasted patient pool (2024-2034) across the seven major markets?
What are the key factors driving the epidemiological trend of acute kidney injury?
What will be the growth rate of patients across the seven major markets?

Acute Kidney Injury: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

What are the current marketed drugs and what are their market performance?
What are the key pipeline drugs and how are they expected to perform in the coming years?
How safe are the current marketed drugs and what are their efficacies?
How safe are the late-stage pipeline drugs and what are their efficacies?
What are the current treatment guidelines for acute kidney injury drugs across the seven major markets?
Who are the key companies in the market and what are their market shares?
What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the acute kidney injury market?
What are the key regulatory events related to the acute kidney injury market?
What is the structure of clinical trial landscape by status related to the acute kidney injury market?
What is the structure of clinical trial landscape by phase related to the acute kidney injury market?
What is the structure of clinical trial landscape by route of administration related to the acute kidney injury market?
1 PREFACE

2 SCOPE AND METHODOLOGY

2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
  2.3.1 Primary Sources
  2.3.2 Secondary Sources
2.4 Market Estimation
  2.4.1 Bottom-Up Approach
  2.4.2 Top-Down Approach
2.5 Forecasting Methodology

3 EXECUTIVE SUMMARY

4 ACUTE KIDNEY INJURY - INTRODUCTION

4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence

5 ACUTE KIDNEY INJURY - DISEASE OVERVIEW

5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment

6 PATIENT JOURNEY

7 ACUTE KIDNEY INJURY - EPIDEMIOLOGY AND PATIENT POPULATION

7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
  7.2.1 Epidemiology Scenario (2018-2023)
  7.2.2 Epidemiology Forecast (2024-2034)
  7.2.3 Epidemiology by Age (?2018-2034?)
  7.2.4 Epidemiology by Gender (?2018-2034?)
  7.2.5 Diagnosed Cases (?2018-2034?)
  7.2.6 Patient Pool/Treated Cases (?2018-2034?)
7.3 Epidemiology Scenario - United States
  7.3.1 Epidemiology Scenario (2018-2023)
  7.3.2 Epidemiology Forecast (2024-2034)
  7.3.3 Epidemiology by Age (?2018-2034?)
  7.3.4 Epidemiology by Gender (?2018-2034?)
  7.3.5 Diagnosed Cases (?2018-2034?)
  7.3.6 Patient Pool/Treated Cases (?2018-2034?)
7.4 Epidemiology Scenario - Germany
  7.4.1 Epidemiology Scenario (2018-2023)
  7.4.2 Epidemiology Forecast (2024-2034)
  7.4.3 Epidemiology by Age (?2018-2034?)
  7.4.4 Epidemiology by Gender (?2018-2034?)
  7.4.5 Diagnosed Cases (?2018-2034?)
  7.4.6 Patient Pool/Treated Cases (?2018-2034?)
7.5 Epidemiology Scenario - France
  7.5.1 Epidemiology Scenario (2018-2023)
  7.5.2 Epidemiology Forecast (2024-2034)
  7.5.3 Epidemiology by Age (?2018-2034?)
  7.5.4 Epidemiology by Gender (?2018-2034?)
  7.5.5 Diagnosed Cases (?2018-2034?)
  7.5.6 Patient Pool/Treated Cases (?2018-2034?)
7.6 Epidemiology Scenario - United Kingdom
  7.6.1 Epidemiology Scenario (2018-2023)
  7.6.2 Epidemiology Forecast (2024-2034)
  7.6.3 Epidemiology by Age (?2018-2034?)
  7.6.4 Epidemiology by Gender (?2018-2034?)
  7.6.5 Diagnosed Cases (?2018-2034?)
  7.6.6 Patient Pool/Treated Cases (?2018-2034?)
7.7 Epidemiology Scenario - Italy
  7.7.1 Epidemiology Scenario (2018-2023)
  7.7.2 Epidemiology Forecast (2024-2034)
  7.7.3 Epidemiology by Age (?2018-2034?)
  7.7.4 Epidemiology by Gender (?2018-2034?)
  7.7.5 Diagnosed Cases (?2018-2034?)
  7.7.6 Patient Pool/Treated Cases (?2018-2034?)
7.8 Epidemiology Scenario - Spain
  7.8.1 Epidemiology Scenario (2018-2023)
  7.8.2 Epidemiology Forecast (2024-2034)
  7.8.3 Epidemiology by Age (?2018-2034?)
  7.8.4 Epidemiology by Gender (?2018-2034?)
  7.8.5 Diagnosed Cases (?2018-2034?)
  7.8.6 Patient Pool/Treated Cases (?2018-2034?)
7.9 Epidemiology Scenario - Japan
  7.9.1 Epidemiology Scenario (2018-2023)
  7.9.2 Epidemiology Forecast (2024-2034)
  7.9.3 Epidemiology by Age (?2018-2034?)
  7.9.4 Epidemiology by Gender (?2018-2034?)
  7.9.5 Diagnosed Cases (?2018-2034?)
  7.9.6 Patient Pool/Treated Cases (?2018-2034?)

8 ACUTE KIDNEY INJURY - TREATMENT ALGORITHM, GUIDELINES, AND MEDICAL PRACTICES

8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm

9 ACUTE KIDNEY INJURY - UNMET NEEDS

10 ACUTE KIDNEY INJURY - KEY ENDPOINTS OF TREATMENT

11 ACUTE KIDNEY INJURY - MARKETED PRODUCTS

11.1 List of Acute Kidney Injury Marketed Drugs Across the Top 7 Markets
  11.1.1 Drug Name - Company Name
    11.1.1.1 Drug Overview
    11.1.1.2 Mechanism of Action
    11.1.1.3 Regulatory Status
    11.1.1.4 Clinical Trial Results
    11.1.1.5 Sales Across Major Markets
Kindly note that the complete list of marketed drugs has been provided in the report.

12 ACUTE KIDNEY INJURY - PIPELINE DRUGS

12.1 List of Acute Kidney Injury Pipeline Drugs Across the Top 7 Markets
  12.1.1 SBI 101 - Sentien Biotechnologies
    12.1.1.1 Drug Overview
    12.1.1.2 Mechanism of Action
    12.1.1.3 Clinical Trial Results
    12.1.1.4 Safety and Efficacy
    12.1.1.5 Regulatory Status
  12.1.2 TIN816 - Novartis
    12.1.2.1 Drug Overview
    12.1.2.2 Mechanism of Action
    12.1.2.3 Clinical Trial Results
    12.1.2.4 Safety and Efficacy
    12.1.2.5 Regulatory Status
  12.1.3 RMC 035 - Guard Therapeutics
    12.1.3.1 Drug Overview
    12.1.3.2 Mechanism of Action
    12.1.3.3 Clinical Trial Results
    12.1.3.4 Safety and Efficacy
    12.1.3.5 Regulatory Status
  12.1.4 RBT-1 - Renibus Therapeutics
    12.1.4.1 Drug Overview
    12.1.4.2 Mechanism of Action
    12.1.4.3 Clinical Trial Results
    12.1.4.4 Safety and Efficacy
    12.1.4.5 Regulatory Status
  12.1.5 OCE 205 - Ocelot Bio
    12.1.5.1 Drug Overview
    12.1.5.2 Mechanism of Action
    12.1.5.3 Clinical Trial Results
    12.1.5.4 Safety and Efficacy
    12.1.5.5 Regulatory Status
Kindly note that the above only represents a partial list of pipeline drugs, and the complete list has been provided in the report.

13. ACUTE KIDNEY INJURY - ATTRIBUTE ANALYSIS OF KEY MARKETED AND PIPELINE DRUGS

14. ACUTE KIDNEY INJURY – CLINICAL TRIAL LANDSCAPE

14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events

15 ACUTE KIDNEY INJURY - MARKET SCENARIO

15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
  15.2.1 Acute Kidney Injury - Market Size
    15.2.1.1 Market Size (2018-2023)
    15.2.1.2 Market Forecast (2024-2034)
  15.2.2 Acute Kidney Injury - Market Size by Therapies
    15.2.2.1 Market Size by Therapies (2018-2023)
    15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
  15.3.1 Acute Kidney Injury - Market Size
    15.3.1.1 Market Size (2018-2023)
    15.3.1.2 Market Forecast (2024-2034)
  15.3.2 Acute Kidney Injury - Market Size by Therapies
    15.3.2.1 Market Size by Therapies (2018-2023)
    15.3.2.2 Market Forecast by Therapies (2024-2034)
  15.3.3 Acute Kidney Injury - Access and Reimbursement Overview
15.4 Market Scenario - Germany
  15.4.1 Acute Kidney Injury - Market Size
    15.4.1.1 Market Size (2018-2023)
    15.4.1.2 Market Forecast (2024-2034)
  15.4.2 Acute Kidney Injury - Market Size by Therapies
    15.4.2.1 Market Size by Therapies (2018-2023)
    15.4.2.2 Market Forecast by Therapies (2024-2034)
  15.4.3 Acute Kidney Injury - Access and Reimbursement Overview
15.5 Market Scenario - France
  15.5.1 Acute Kidney Injury - Market Size
    15.5.1.1 Market Size (2018-2023)
    15.5.1.2 Market Forecast (2024-2034)
  15.5.2 Acute Kidney Injury - Market Size by Therapies
    15.5.2.1 Market Size by Therapies (2018-2023)
    15.5.2.2 Market Forecast by Therapies (2024-2034)
  15.5.3 Acute Kidney Injury - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
  15.6.1 Acute Kidney Injury - Market Size
    15.6.1.1 Market Size (2018-2023)
    15.6.1.2 Market Forecast (2024-2034)
  15.6.2 Acute Kidney Injury - Market Size by Therapies
    15.6.2.1 Market Size by Therapies (2018-2023)
    15.6.2.2 Market Forecast by Therapies (2024-2034)
  15.6.3 Acute Kidney Injury - Access and Reimbursement Overview
15.7 Market Scenario - Italy
  15.7.1 Acute Kidney Injury - Market Size
    15.7.1.1 Market Size (2018-2023)
    15.7.1.2 Market Forecast (2024-2034)
  15.7.2 Acute Kidney Injury - Market Size by Therapies
    15.7.2.1 Market Size by Therapies (2018-2023)
    15.7.2.2 Market Forecast by Therapies (2024-2034)
  15.7.3 Acute Kidney Injury - Access and Reimbursement Overview
15.8 Market Scenario - Spain
  15.8.1 Acute Kidney Injury - Market Size
    15.8.1.1 Market Size (2018-2023)
    15.8.1.2 Market Forecast (2024-2034)
  15.8.2 Acute Kidney Injury - Market Size by Therapies
    15.8.2.1 Market Size by Therapies (2018-2023)
    15.8.2.2 Market Forecast by Therapies (2024-2034)
  15.8.3 Acute Kidney Injury - Access and Reimbursement Overview
15.9 Market Scenario - Japan
  15.9.1 Acute Kidney Injury - Market Size
    15.9.1.1 Market Size (2018-2023)
    15.9.1.2 Market Forecast (2024-2034)
  15.9.2 Acute Kidney Injury - Market Size by Therapies
    15.9.2.1 Market Size by Therapies (2018-2023)
    15.9.2.2 Market Forecast by Therapies (2024-2034)
  15.9.3 Acute Kidney Injury - Access and Reimbursement Overview

16 ACUTE KIDNEY INJURY - RECENT EVENTS AND INPUTS FROM KEY OPINION LEADERS

17 ACUTE KIDNEY INJURY MARKET - SWOT ANALYSIS

17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats

18 ACUTE KIDNEY INJURY MARKET – STRATEGIC RECOMMENDATIONS

19 APPENDIX


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