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Actinic Keratosis Treatment Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Therapy (Topical, Surgery, Photodynamic Therapy), By Drug Class (Nucleoside metabolic inhibitor, NSAIDS, Immune response modifiers, Photoenhancers, Others), By End User (Hospitals & Clinics, Ambulatory Care Centers, Others), By Region and Competition, 2019-2029F

May 2024 | 182 pages | ID: AF9BC5A2C902EN
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Global Actinic Keratosis Treatment Market was valued at USD 6.82 Billion in 2023 and is anticipated t%li%project steady growth in the forecast period with a CAGR of 4.25% through 2029. Actinic keratosis (AK) is a common skin condition caused by prolonged exposure t%li%the sun's harmful ultraviolet (UV) rays. It is characterized by the development of rough, scaly patches on the skin, which, if left untreated, can progress t%li%skin cancer. With increasing awareness about skin health and a growing aging population, the global actinic keratosis treatment market has witnessed significant growth in recent years. As the global population ages, the prevalence of actinic keratosis increases. The baby boomer generation is particularly susceptible t%li%AK due t%li%their prolonged sun exposure over their lifetimes. Greater awareness about skin health, sun protection, and the risks associated with actinic keratosis has prompted more individuals t%li%seek treatment and preventive measures. Ongoing research and development efforts have led t%li%the development of new and more effective treatments, further boosting the market's growth. Topical treatments are often the first line of defense against actinic keratosis. They include creams and gels containing ingredients such as 5-fluorouracil (5-FU), imiquimod, and diclofenac. These medications work by targeting and eliminating precancerous skin cells. Cryotherapy involves freezing the affected skin using liquid nitrogen. This treatment method is quick, cost-effective, and is often used for isolated AK lesions. Photodynamic Therapy (PDT) involves the application of a light-activated photosensitizing agent t%li%the affected skin, followed by exposure t%li%a specific wavelength of light. This activates the agent, which then selectively destroys AK cells. Laser treatment uses high-energy light t%li%target and remove the abnormal skin cells. It is effective for more severe or extensive AK lesions. In some cases, particularly when there is a suspicion of skin cancer, surgical removal of the affected area may be necessary. This ensures that any potential cancerous cells are completely removed.

Key Market Drivers

Rising Incidence of Actinic Keratosis

Actinic keratosis (AK), als%li%known as solar keratosis or senile keratosis, is a common skin condition characterized by the development of small, scaly patches on the skin's surface. These lesions are caused by prolonged exposure t%li%ultraviolet (UV) radiation, primarily from the sun. Although AK is considered a precancerous condition, it has the potential t%li%progress int%li%squamous cell carcinoma if left untreated. This threat has driven the demand for effective treatments, contributing t%li%the growth of the global actinic keratosis treatment market. The incidence of actinic keratosis is on the rise worldwide, making it a significant public health concern. The primary factor contributing t%li%this increase is the greater awareness of the dangers of excessive sun exposure and the importance of early detection and treatment. Additionally, the aging population, particularly in developed countries, has further fueled the growth of actinic keratosis cases. As populations age and UV exposure accumulates over time, the likelihood of developing AK and other skin-related conditions, including skin cancers, rises. The connection between AK and squamous cell carcinoma is a major driver of the global actinic keratosis treatment market, as early intervention can prevent the progression t%li%a more severe form of cancer.

Recent years have seen significant advancements in the treatment options available for actinic keratosis. Topical therapies, cryotherapy, photodynamic therapy, and laser treatments have become more effective, with fewer side effects and shorter recovery times. These innovations have spurred the adoption of treatment, further boosting the actinic keratosis treatment market. Public awareness of the risks associated with actinic keratosis and skin cancer has grown substantially. Skin cancer prevention campaigns, as well as regular skin check-ups, have led t%li%earlier diagnoses and subsequent treatment. This heightened awareness has created a greater demand for AK treatment, thereby driving market growth. The global population is aging, especially in developed countries where the prevalence of AK is higher due t%li%a history of sun exposure. As people age, the likelihood of developing actinic keratosis increases. This demographic trend acts as a natural driver for the market, as a growing patient pool seeks treatment.

Innovations in medical technology, such as the development of non-invasive treatment options, have significantly expanded the treatment landscape for AK. Laser therapies, for example, offer targeted and precise removal of affected skin without causing extensive damage t%li%surrounding tissue. Health authorities and regulatory bodies have been instrumental in promoting the safe and effective treatment of actinic keratosis. Their guidelines and approvals for new treatment options have provided both healthcare providers and patients with the assurance of quality care, further driving market growth.

Expanding Aging Population

The global population is experiencing a demographic shift with significant implications for healthcare. One of the most prominent trends in this shift is the increasing number of elderly individuals. According t%li%the World Health Organization (WHO), the proportion of the global population aged 60 and over is expected t%li%double by 2050, reaching approximately 22% of the total population. This trend is observed across the world, with many countries witnessing a surge in the elderly population. Factors contributing t%li%the aging population include increased life expectancy due t%li%advancements in healthcare and a decrease in birth rates in some countries. As a result, healthcare systems are being challenged t%li%provide quality care and effective treatments for age-related conditions, such as actinic keratosis.

Actinic keratosis is a skin condition characterized by the development of small, scaly patches on the skin's surface. These patches are usually rough, dry, and may be red, brown, or skin-colored. They are considered precancerous lesions, and if left untreated, they can progress t%li%squamous cell carcinoma, a type of skin cancer. The primary cause of actinic keratosis is prolonged exposure t%li%ultraviolet (UV) radiation, mainly from the sun. Over time, cumulative sun damage can lead t%li%the development of these lesions. As the aging population continues t%li%grow, the prevalence of actinic keratosis cases is expected t%li%rise due t%li%the cumulative effects of UV exposure over the years.

The expanding aging population has generated a substantial increase in the demand for actinic keratosis treatments. This surge in demand has prompted the growth of the global actinic keratosis treatment market. The pharmaceutical and healthcare industries have responded t%li%the rising demand by developing innovative treatments for actinic keratosis. These treatments include topical creams, cryotherapy, laser therapy, and photodynamic therapy, among others. Increased awareness of the risks associated with sun exposure and regular skin screenings have led t%li%early detection of actinic keratosis. This, in turn, has driven the demand for treatment options, as early intervention can prevent the progression t%li%skin cancer. Governments and healthcare organizations are allocating more resources t%li%address the healthcare needs of an aging population. This includes funding for dermatological services and treatments for age-related skin conditions. Developing countries, where the aging population is als%li%on the rise, are witnessing an expansion of the actinic keratosis treatment market as healthcare infrastructure and access t%li%healthcare services improve.

Key Market Challenges

Limited Awareness

The primary challenges for the actinic keratosis treatment market is the lack of awareness among the general population. Many individuals are unaware of the risks associated with actinic keratosis and may not recognize its symptoms. As a result, a large number of cases g%li%undiagnosed and untreated. T%li%address this issue, public health campaigns and educational initiatives are necessary t%li%raise awareness about actinic keratosis, its risk factors, and the importance of early treatment.

High Treatment Costs

Actinic keratosis treatments can be costly, especially for advanced cases that require multiple sessions of therapy. These high treatment costs can act as a barrier t%li%access for many patients, leading t%li%delayed or inadequate treatment. Pharmaceutical companies and healthcare providers need t%li%work together t%li%make treatments more affordable and accessible, possibly through the development of cost-effective treatment options and increased insurance coverage for actinic keratosis therapy.

Limited Treatment Options

The current treatment options for actinic keratosis are somewhat limited, with common approaches including cryotherapy, topical medications, laser therapy, and photodynamic therapy. While these treatments can be effective, they may not be suitable for all patients. Developing innovative and more targeted therapies is a challenge in the field, but it is essential for improving treatment outcomes and reducing side effects.

Key Market Trends

Technological Advancements

Actinic keratosis (AK), often referred t%li%as solar keratosis or senile keratosis, is a common skin condition caused by prolonged exposure t%li%ultraviolet (UV) radiation from the sun. If left untreated, it can progress int%li%a more serious form of skin cancer known as squamous cell carcinoma. As the prevalence of AK continues t%li%rise due t%li%increasing sun exposure and an aging population, the global market for actinic keratosis treatment is expanding. However, it's not just the growing prevalence of AK that is driving this market; technological advancements are playing a crucial role in the development of more effective and patient-friendly treatments.

The key technological advancements in the AK treatment market is the development of non-invasive therapies. Traditionally, AK lesions were treated with cryotherapy (freezing), curettage (scraping), or topical treatments. While these methods are effective, they can be painful and may lead t%li%scarring. Newer technologies, such as photodynamic therapy (PDT) and laser therapy, offer non-invasive alternatives that target AK lesions with precision, minimizing pain and scarring. PDT, for instance, uses a photosensitizing agent and specific light wavelengths t%li%destroy AK lesions without causing significant damage t%li%surrounding healthy tissue. Advances in topical medications have als%li%greatly improved AK treatment. Prescription creams containing 5-fluorouracil (5-FU), imiquimod, or diclofenac can effectively target and eliminate AK lesions with minimal side effects. These topical treatments are more patient-friendly compared t%li%traditional approaches, and they are increasingly favored by both patients and healthcare providers. Telemedicine and teledermatology have become instrumental in AK diagnosis and treatment. With the advent of smartphones and high-quality imaging technologies, patients can easily send photos of their skin lesions t%li%dermatologists for evaluation. This allows for quicker diagnosis and treatment planning, reducing the need for in-person visits. Additionally, teledermatology has improved follow-up care, ensuring that patients adhere t%li%their treatment regimens. Advancements in understanding the molecular and genetic underpinnings of AK have led t%li%the development of targeted therapies. Medications that specifically target the pathways responsible for AK development have shown promising results. These therapies not only improve treatment efficacy but als%li%reduce side effects, making them more patient-friendly. Accurate diagnosis and assessment of AK lesions are critical for effective treatment. 3D imaging and biopsies have improved the precision of diagnosis, helping healthcare providers identify high-risk lesions that require more aggressive treatment. This technological advance ensures that treatment efforts are appropriately directed.

The combination of these technological advancements has not only improved the patient experience but has als%li%expanded the market for AK treatment. More patients are seeking treatment for AK, and they are increasingly willing t%li%explore newer, less invasive options. As a result, the global market for actinic keratosis treatment is projected t%li%experience significant growth in the coming years. Additionally, increased awareness about the risks of AK and skin cancer has prompted individuals t%li%seek medical advice and treatment at an earlier stage. The role of technology in educating and engaging patients cannot be underestimated. Mobile applications, websites, and telemedicine platforms are now being used t%li%disseminate information and facilitate consultations.

Segmental Insights

Therapy Insights

Based on the category of therapy, Surgery emerged as the dominant player in the global market for Actinic Keratosis Treatment in 2023. Several treatment options are available for actinic keratosis, including topical treatments, cryotherapy, photodynamic therapy, laser therapy, and surgery. While each method has its merits, surgical procedures have stood the test of time as an effective means of treatment. Surgical procedures ensure complete removal of the affected tissue, reducing the risk of recurrence and progression t%li%squamous cell carcinoma. Techniques like Mohs micrographic surgery and excision are highly precise, preserving healthy tissue while eliminating the disease. Surgery often provides immediate results, with improved skin appearance and reduced discomfort for patients. Surgery not only treats actinic keratosis but als%li%improves the overall health and appearance of the skin, making it a favourable option for many patients.

Drug Class Insights

The Nucleoside metabolic inhibitors segment is projected t%li%experience rapid growth during the forecast period. Nucleoside metabolic inhibitors are a class of medications that interfere with the metabolic processes of rapidly dividing cells, making them particularly effective for the treatment of precancerous lesions like actinic keratosis. They work by disrupting the synthesis of DNA and RNA, causing cell death in the affected areas. These medications have demonstrated high success rates in clearing actinic keratosis lesions, reducing the risk of progression t%li%squamous cell carcinoma. Many nucleoside metabolic inhibitors have shorter treatment durations compared t%li%other therapies, making them more convenient for patients. Topical application minimizes the need for surgical procedures, reducing the risk of scarring and infection. Nucleoside metabolic inhibitors can be applied at home, promoting better patient compliance.

Regional Insights

North America emerged as the dominant region in the global Actinic Keratosis Treatment market in 2023, holding the largest market share in terms of value. North America has one of the highest incidence rates of actinic keratosis globally. This high prevalence is attributed t%li%factors like excessive UV exposure, fair skin populations, and an aging demographic. As a result, North America represents a substantial patient pool, contributing significantly t%li%the region's dominance in the actinic keratosis treatment market. The healthcare infrastructure in North America is well-developed and technologically advanced. The region boasts numerous dermatology clinics and healthcare facilities that offer state-of-the-art actinic keratosis treatment options. This includes a wide array of topical therapies, cryotherapy, photodynamic therapy, and surgical excisions.

Key Market Players
  • Almirall S.A.
  • LEO Pharma A/S
  • Sun Pharmaceutical Industries Ltd.
  • Novartis AG
  • GALDERMA SA
    • Orth%li%Dermatologics (Bausch Health Companies Inc.)
  • BIOFRONTERA AG
  • Hill Dermaceuticals, Inc.
Report Scope:

In this report, the Global Actinic Keratosis Treatment Market has been segmented int%li%the following categories, in addition t%li%the industry trends which have als%li%been detailed below:
  • Actinic Keratosis Treatment Market, By Therapy:
  • Topical
  • Surgery
  • Photodynamic Therapy
  • Actinic Keratosis Treatment Market, By Drug Class:
  • Nucleoside metabolic inhibitor
  • NSAIDS
  • Immune response modifiers
  • Photoenhancers
  • Others
  • Actinic Keratosis Treatment Market, By End User:
  • Hospitals & Clinics
  • Ambulatory Care Centers
  • Others
  • Actinic Keratosis Treatment Market, By Region:
  • North America
  • United States
  • Canada
  • Mexico
  • Europe
  • France
  • United Kingdom
  • Italy
  • Germany
  • Spain
  • Asia-Pacific
  • China
  • India
  • Japan
  • Australia
  • South Korea
  • South America
  • Brazil
  • Argentina
  • Colombia
  • Middle East & Africa
  • South Africa
  • Saudi Arabia
  • UAE
Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the Actinic Keratosis Treatment Market.

Available Customizations:

Global Actinic Keratosis Treatment market report with the given market data, Tech Sci Research offers customizations according t%li%a company's specific needs. The following customization options are available for the report:

Company Information
    • Detailed analysis and profiling of additional market players (up t%li%five).
1. PRODUCT OVERVIEW

1.1. Market Definition
1.2. Scope of the Market
  1.2.1. Markets Covered
  1.2.2. Years Considered for Study
  1.2.3. Key Market Segmentations

2. RESEARCH METHODOLOGY

2.1. Objective of the Study
2.2. Baseline Methodology
2.3. Key Industry Partners
2.4. Major Association and Secondary Sources
2.5. Forecasting Methodology
2.6. Data Triangulation & Validation
2.7. Assumptions and Limitations

3. EXECUTIVE SUMMARY

3.1. Overview of the Market
3.2. Overview of Key Market Segmentations
3.3. Overview of Key Market Players
3.4. Overview of Key Regions/Countries
3.5. Overview of Market Drivers, Challenges, Trends

4. GLOBAL ACTINIC KERATOSIS TREATMENT MARKET OUTLOOK

4.1. Market Size & Forecast
  4.1.1. By Value
4.2. Market Share & Forecast
  4.2.1. By Therapy (Topical, Surgery, Photodynamic Therapy)
  4.2.2. By Drug Class (Nucleoside metabolic inhibitor, NSAIDS, Immune response modifiers, Photoenhancers, Others)
  4.2.3. By End user (Hospitals & Clinics, Ambulatory Care Centers, Others)
  4.2.4. By Region
  4.2.5. By Company (2023)
4.3. Market Map
  4.3.1. By Therapy
  4.3.2. By Drug Class
  4.3.3. By End user
  4.3.4. By Region

5. ASIA PACIFIC ACTINIC KERATOSIS TREATMENT MARKET OUTLOOK

5.1. Market Size & Forecast
  5.1.1. By Value
5.2. Market Share & Forecast
  5.2.1. By Therapy
  5.2.2. By Drug Class
  5.2.3. By End user
  5.2.4. By Country
5.3. Asia Pacific: Country Analysis
  5.3.1. China Actinic Keratosis Treatment Market Outlook
    5.3.1.1. Market Size & Forecast
      5.3.1.1.1. By Value
    5.3.1.2. Market Share & Forecast
      5.3.1.2.1. By Therapy
      5.3.1.2.2. By Drug Class
      5.3.1.2.3. By End user
  5.3.2. India Actinic Keratosis Treatment Market Outlook
    5.3.2.1. Market Size & Forecast
      5.3.2.1.1. By Value
    5.3.2.2. Market Share & Forecast
      5.3.2.2.1. By Therapy
      5.3.2.2.2. By Drug Class
      5.3.2.2.3. By End user
  5.3.3. Australia Actinic Keratosis Treatment Market Outlook
    5.3.3.1. Market Size & Forecast
      5.3.3.1.1. By Value
    5.3.3.2. Market Share & Forecast
      5.3.3.2.1. By Therapy
      5.3.3.2.2. By Drug Class
      5.3.3.2.3. By End user
  5.3.4. Japan Actinic Keratosis Treatment Market Outlook
    5.3.4.1. Market Size & Forecast
      5.3.4.1.1. By Value
    5.3.4.2. Market Share & Forecast
      5.3.4.2.1. By Therapy
      5.3.4.2.2. By Drug Class
      5.3.4.2.3. By End user
  5.3.5. South Korea Actinic Keratosis Treatment Market Outlook
    5.3.5.1. Market Size & Forecast
      5.3.5.1.1. By Value
    5.3.5.2. Market Share & Forecast
      5.3.5.2.1. By Therapy
      5.3.5.2.2. By Drug Class
      5.3.5.2.3. By End user

6. EUROPE ACTINIC KERATOSIS TREATMENT MARKET OUTLOOK

6.1. Market Size & Forecast
  6.1.1. By Value
6.2. Market Share & Forecast
  6.2.1. By Therapy
  6.2.2. By Drug Class
  6.2.3. By End user
  6.2.4. By Country
6.3. Europe: Country Analysis
  6.3.1. France Actinic Keratosis Treatment Market Outlook
    6.3.1.1. Market Size & Forecast
      6.3.1.1.1. By Value
    6.3.1.2. Market Share & Forecast
      6.3.1.2.1. By Therapy
      6.3.1.2.2. By Drug Class
      6.3.1.2.3. By End user
  6.3.2. Germany Actinic Keratosis Treatment Market Outlook
    6.3.2.1. Market Size & Forecast
      6.3.2.1.1. By Value
    6.3.2.2. Market Share & Forecast
      6.3.2.2.1. By Therapy
      6.3.2.2.2. By Drug Class
      6.3.2.2.3. By End user
  6.3.3. Spain Actinic Keratosis Treatment Market Outlook
    6.3.3.1. Market Size & Forecast
      6.3.3.1.1. By Value
    6.3.3.2. Market Share & Forecast
      6.3.3.2.1. By Therapy
      6.3.3.2.2. By Drug Class
      6.3.3.2.3. By End user
  6.3.4. Italy Actinic Keratosis Treatment Market Outlook
    6.3.4.1. Market Size & Forecast
      6.3.4.1.1. By Value
    6.3.4.2. Market Share & Forecast
      6.3.4.2.1. By Therapy
      6.3.4.2.2. By Drug Class
      6.3.4.2.3. By End user
  6.3.5. United Kingdom Actinic Keratosis Treatment Market Outlook
    6.3.5.1. Market Size & Forecast
      6.3.5.1.1. By Value
    6.3.5.2. Market Share & Forecast
      6.3.5.2.1. By Therapy
      6.3.5.2.2. By Drug Class
      6.3.5.2.3. By End user

7. NORTH AMERICA ACTINIC KERATOSIS TREATMENT MARKET OUTLOOK

7.1. Market Size & Forecast
  7.1.1. By Value
7.2. Market Share & Forecast
  7.2.1. By Therapy
  7.2.2. By Drug Class
  7.2.3. By End user
  7.2.4. By Country
7.3. North America: Country Analysis
  7.3.1. United States Actinic Keratosis Treatment Market Outlook
    7.3.1.1. Market Size & Forecast
      7.3.1.1.1. By Value
    7.3.1.2. Market Share & Forecast
      7.3.1.2.1. By Therapy
      7.3.1.2.2. By Drug Class
      7.3.1.2.3. By End user
  7.3.2. Mexico Actinic Keratosis Treatment Market Outlook
    7.3.2.1. Market Size & Forecast
      7.3.2.1.1. By Value
    7.3.2.2. Market Share & Forecast
      7.3.2.2.1. By Therapy
      7.3.2.2.2. By Drug Class
      7.3.2.2.3. By End user
  7.3.3. Canada Actinic Keratosis Treatment Market Outlook
    7.3.3.1. Market Size & Forecast
      7.3.3.1.1. By Value
    7.3.3.2. Market Share & Forecast
      7.3.3.2.1. By Therapy
      7.3.3.2.2. By Drug Class
      7.3.3.2.3. By End user

8. SOUTH AMERICA ACTINIC KERATOSIS TREATMENT MARKET OUTLOOK

8.1. Market Size & Forecast
  8.1.1. By Value
8.2. Market Share & Forecast
  8.2.1. By Therapy
  8.2.2. By Drug Class
  8.2.3. By End user
  8.2.4. By Country
8.3. South America: Country Analysis
  8.3.1. Brazil Actinic Keratosis Treatment Market Outlook
    8.3.1.1. Market Size & Forecast
      8.3.1.1.1. By Value
    8.3.1.2. Market Share & Forecast
      8.3.1.2.1. By Therapy
      8.3.1.2.2. By Drug Class
      8.3.1.2.3. By End user
  8.3.2. Argentina Actinic Keratosis Treatment Market Outlook
    8.3.2.1. Market Size & Forecast
      8.3.2.1.1. By Value
    8.3.2.2. Market Share & Forecast
      8.3.2.2.1. By Therapy
      8.3.2.2.2. By Drug Class
      8.3.2.2.3. By End user
  8.3.3. Colombia Actinic Keratosis Treatment Market Outlook
    8.3.3.1. Market Size & Forecast
      8.3.3.1.1. By Value
    8.3.3.2. Market Share & Forecast
      8.3.3.2.1. By Therapy
      8.3.3.2.2. By Drug Class
      8.3.3.2.3. By End user

9. MIDDLE EAST AND AFRICA ACTINIC KERATOSIS TREATMENT MARKET OUTLOOK

9.1. Market Size & Forecast
  9.1.1. By Value
9.2. Market Share & Forecast
  9.2.1. By Therapy
  9.2.2. By Drug Class
  9.2.3. By End user
  9.2.4. By Country
9.3. MEA: Country Analysis
  9.3.1. South Africa Actinic Keratosis Treatment Market Outlook
    9.3.1.1. Market Size & Forecast
      9.3.1.1.1. By Value
    9.3.1.2. Market Share & Forecast
      9.3.1.2.1. By Therapy
      9.3.1.2.2. By Drug Class
      9.3.1.2.3. By End user
  9.3.2. Saudi Arabia Actinic Keratosis Treatment Market Outlook
    9.3.2.1. Market Size & Forecast
      9.3.2.1.1. By Value
    9.3.2.2. Market Share & Forecast
      9.3.2.2.1. By Therapy
      9.3.2.2.2. By Drug Class
      9.3.2.2.3. By End user
  9.3.3. UAE Actinic Keratosis Treatment Market Outlook
    9.3.3.1. Market Size & Forecast
      9.3.3.1.1. By Value
    9.3.3.2. Market Share & Forecast
      9.3.3.2.1. By Therapy
      9.3.3.2.2. By Drug Class
      9.3.3.2.3. By End user

10. MARKET DYNAMICS

10.1. Drivers
10.2. Challenges

11. MARKET TRENDS & DEVELOPMENTS

11.1. Recent Developments
11.2. Product Launches
11.3. Mergers & Acquisitions

12. GLOBAL ACTINIC KERATOSIS TREATMENT MARKET: SWOT ANALYSIS

13. PORTER’S FIVE FORCES ANALYSIS

13.1. Competition in the Industry
13.2. Potential of New Entrants
13.3. Power of Suppliers
13.4. Power of Customers
13.5. Threat of Substitute Product

14. COMPETITIVE LANDSCAPE

14.1. Almirall S.A.
  14.1.1. Business Overview
  14.1.2. Company Snapshot
  14.1.3. Product & Services
  14.1.4. Financials (In case of listed)
  14.1.5. Recent Developments
  14.1.6. SWOT Analysis
14.2. LEO Pharma A/S
14.3. Sun Pharmaceutical Industries Ltd.
14.4. Novartis AG
14.5. GALDERMA SA
14.6. Ortho Dermatologics (Bausch Health Companies Inc.)
14.7. BIOFRONTERA AG
14.8. Hill Dermaceuticals, Inc.

15. STRATEGIC RECOMMENDATIONS

16. ABOUT US & DISCLAIMER


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