Epiomic Epidemiology Series: Restless Leg Syndrome Forecast in 13 Major Markets 2016-2026

January 2016 | 52 pages | ID: EEBC1A13E0BEN
Black Swan Analysis limited

Abstracts

Restless Legs Syndrome (RLS), also known as Willis-Ekbom Disorder, is a sensimotor sleep disorder. Clinically, RLS is characterized by disagreeable leg sensations occurring most often at sleep onset that provoke an irresistible urge to move legs. Patients with RLS typically complain of itching, creeping and tingling in their legs, usually between the ankle and the knee. The unpleasant sensations occur when the individual is at rest and are more pronounced in the evening or at night. The unpleasant sensations are relieved temporarily with leg movements.

This report provides the current prevalent population for Restless Legs Syndrome across 13 Major Markets (USA, France, Germany, Italy, Spain, UK, Turkey, Brazil, Mexico, Republic of Korea, India, China and Japan) split by gender and 5-year age cohort. Along with the current prevalence, the report also contains a disease overview of the risk factors, disease diagnosis and prognosis along with specific variations by geography and ethnicity.

Providing a value-added level of insight from the analysis team at Black Swan, several of the main symptoms and co-morbidities of Restless Legs Syndrome have been quantified and presented alongside the overall prevalence figures. These sub-populations within the main disease are also included at a country level across the 10-year forecast snapshot.

Main symptoms and co-morbidities for Restless Legs Syndrome include:

• Insomnia
• Depression
• Periodic Limb Movements
• Panic Disorder

This report is built using data and information sourced from the proprietary Epiomic patient segmentation database. To generate accurate patient population estimates, the Epiomic database utilises a combination of several world class sources that deliver the most up to date information form patient registries, clinical trials and epidemiology studies. All of the sources used to generate the data and analysis have been identified in the report.

Reasons to buy

• Able to quantify patient populations in global Restless Legs Syndrome’s market to target the development of future products, pricing strategies and launch plans.
• Gain further insight into the prevalence of the subdivided types of Restless Legs Syndrome and identify patient segments with high potential.
• Delivery of more accurate information for clinical trials in study sizing and realistic patient recruitment for various countries.
• Provide a level of understanding on the impact from specific co-morbid conditions on Restless Legs Syndrome’s prevalent population.
• Identify sub-populations within Restless Legs Syndrome which require treatment.
• Gain an understanding of the specific markets that have the largest number of Restless Legs Syndrome patients.

Contents

List of tables and figures
Introduction
Cause of the disease
Risk factors & prevention
Diagnosis of the disease
Variation by geography/ethnicity
Disease prognosis & clinical course
Key comorbid conditions / features associated with the disease
Methodology for quantification of patient numbers
Top-line prevalence for restless legs syndrome
Features of restless legs syndrome
  Type of restless legs syndrome
  Course and severity of restless legs syndrome
Conditions associated with restless legs syndrome
  Sleep disturbance
  Periodic limb movements
  Panic disorder
  Major depressive disorder
Abbreviations used in the report
Other black swan analysis publications
Black swan analysis online patient-based databases
Patient-based offering
Online pricing data & platforms
References
Appendix

List Of Tables

LIST OF TABLES

1. IRLSSG Diagnostic criteria
2. Prevalence of RLS, total (000s)
3. Prevalence of RLS, males (000s)
4. Prevalence of RLS, females (000s)
5. Type of RLS in patients, total (000s)
6. Prevalence of RLS with familial component, total (000s)
7. Type of course in RLS patients, total (000s)
8. Frequency of symptoms in INTERMITTENT RLS patients, total (000s)
9. CHRONIC-PERSISTENT RLS patients ( ≥2 episodes per week), total (000s)
10. Prevalence of Sleep disturbance in RLS patients, total (000s)
11. Prevalence of Periodic Limb Movements in RLS patients, total (000s)
12. Prevalence of Panic disorder in RLS patients, total (000s)
13. Prevalence of Major Depressive Disorder in RLS patients, total (000s)
14. Abbreviations and Acronyms used in the report
15. USA Prevalence of RLS by 5-yr age cohort, males (000s)
16. USA Prevalence of RLS by 5-yr age cohort, females (000s)
17. France Prevalence of RLS by 5-yr age cohort, males (000s)
18. France Prevalence of RLS by 5-yr age cohort, females (000s)
19. Germany Prevalence of RLS by 5-yr age cohort, males (000s)
20. Germany Prevalence of RLS by 5-yr age cohort, females (000s)
21. Italy Prevalence of RLS by 5-yr age cohort, males (000s)
22. Italy Prevalence of RLS by 5-yr age cohort, females (000s)
23. Spain Prevalence of RLS by 5-yr age cohort, males (000s)
24. Spain Prevalence of RLS by 5-yr age cohort, females (000s)
25. United Kingdom Prevalence of RLS by 5-yr age cohort, males (000s)
26. United Kingdom Prevalence of RLS by 5-yr age cohort, females (000s)
27. Brazil Prevalence of RLS by 5-yr age cohort, males (000s)
28. Brazil Prevalence of RLS by 5-yr age cohort, females (000s)
29. Japan Prevalence of RLS by 5-yr age cohort, males (000s)
30. Japan Prevalence of RLS by 5-yr age cohort, females (000s)
31. India Prevalence of RLS by 5-yr age cohort, males (000s)
32. India Prevalence of RLS by 5-yr age cohort, females (000s)
33. Mexico Prevalence of RLS by 5-yr age cohort, males (000s)
34. Mexico Prevalence of RLS by 5-yr age cohort, females (000s)
35. Turkey Prevalence of RLS by 5-yr age cohort, males (000s)
36. Turkey Prevalence of RLS by 5-yr age cohort, females (000s)
37. Republic of Korea Prevalence of RLS by 5-yr age cohort, males (000s)
38. Republic of Korea Prevalence of RLS by 5-yr age cohort, females (000s)
39. China Prevalence of RLS by 5-yr age cohort, males (000s)
40. China Prevalence of RLS by 5-yr age cohort, females (000s)