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Molecular Cloning Kits Market, 2022-2035: Distribution by Type of Cloning Method (Blunt End Cloning, Ligase Independent Cloning, PCR Cloning, Seamless Cloning, TA Cloning and Other Methods), End-Users (Academic and Research Institutes, Pharmaceutical and Biotechnology Companies, Hospitals and Clinics, and Other End-Users) and Key Geographical Regions (North America, Europe, Asia Pacific, Latin America, and Middle East and North Africa): Industry Trends and Global Forecasts, 2022-2035

August 2023 | 238 pages | ID: M510E0BCA994EN
Roots Analysis

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The projected value of molecular cloning kits market is expected to be valued at USD 0.362 billion in 2022 and is anticipated to grow at a CAGR of 25% during the forecast period 2022-2035.

The landscape of gene cloning, historically underexplored, experienced a transformative moment in 1973. A seminal report by A. C. Y. Chang, H. W. Boyer, R. B. Helling, and Stanley N. Cohen marked a pivotal milestone, revealing the potential to clone and isolate individual genes through enzymatic cleavage of DNA into fragments. The ensuing decades witnessed the evolution of genome engineering techniques, facilitating genome alterations in microorganisms and unlocking the capability to produce substances with diverse research and therapeutic applications.

DNA cloning, a meticulously regulated method, has gained widespread recognition and adoption across laboratories worldwide. Notably, amidst the global COVID-19 pandemic, prominent pharmaceutical and biopharmaceutical entities, alongside key players in the synthetic biology market, have actively contributed to research and development endeavors. Their focus encompassed an array of products, including test kits, treatment solutions, and vaccines, employing synthetic biology to combat coronavirus infections.

In navigating the DNA cloning process, various approaches, such as traditional cloning, PCR cloning, ligation-independent cloning, seamless cloning, and recombinant DNA technology, can be applied based on specific requirements. However, despite notable strides in synthetic biology, the DNA cloning process confronts challenges, such as the need for substantial quantities of expensive cloning vectors, diverse reagents, and extended timeframes for completion.

In response to these challenges, innovators within the pharmaceutical industry have diligently sought ways to enhance the DNA cloning process. Among the emerging alternatives, the utilization of DNA cloning kits has surfaced as a practical choice for drug developers, academic institutions, and research centers seeking to surmount the limitations of traditional methods. The current market boasts over 250 DNA cloning kits, distinguished by their affordability, user-friendly attributes, and ability to yield high-quality results in abbreviated timeframes.

The landscape of DNA cloning technologies is marked by a robust intellectual foundation, with over 3,200 patents and 4,000 research articles published in recent years. This influx of intellectual contributions underscores the innovative endeavors of stakeholders in the molecular cloning market. Fueled by escalating demand for gene therapies and the introduction of novel DNA cloning technologies, the molecular cloning market is poised for steady growth in the foreseeable future.

Research Coverage
  • DNA Cloning Overview provides a comprehensive look at DNA cloning methods, types of kits and reagents (PCR cloning, TOPO cloning), and discusses advantages, applications, challenges, and future perspectives.
  • Market Landscape - DNA Cloning Kits offers an overview of current DNA cloning kit market based on components, reactions, cloning methods, fragment types, cloning time, shelf life, and price. Includes analysis of kit providers.
  • Elaborated profiles on key players in North America, Europe, and Asia Pacific, including company overview, financials (if available), DNA cloning kit and reagent portfolios, recent developments, and future outlook.
  • Details a review of 4,400+ peer-reviewed articles on DNA cloning since 2018, covering parameters like publication year, article type, publishers, authors, and journals.
  • Analyzes grants awarded for DNA cloning projects (2017-2022) based on year, amount, administering institute, support period, grant application type, purpose, activity code, study section, focus areas, program officers, and recipient organizations' geographical distribution.
  • Examines patents filed/granted for DNA cloning (2017-2021) based on type, publication year, application year, geography, CPC symbols, emerging focus areas, issuing authority, applicant type, leading players, non-industry players, patent assignees, benchmarking, characteristics, age, valuation, and geography.
  • Market forecast analysis for DNA cloning kits (till 2035), segmented by cloning methods, end-users, and geographical regions.
  • A case study on service providers, including year of establishment, company size, headquarters location, and regional presence.
Key Market Companies
  • Thermo Fisher Scientific
  • Merck
  • Takara Bio
  • Vazyme
  • GenScript
  • Promega
  • Agilent Technologies
  • Bio-Rad
1. PREFACE

1.1. Scope of the Report
1.2. Research Methodology
1.3. Key Questions Answered
1.4. Chapter Outlines

2. EXECUTIVE SUMMARY

3. INTRODUCTION

3.1. Chapter Overview
3.2. Introduction to DNA Cloning
3.3. Methods of DNA Cloning
  3.3.1. Restriction Enzyme Based Cloning
  3.3.2. PCR Cloning
  3.3.3. Ligation Independent Cloning
  3.3.4. TA Cloning
  3.3.5. Seamless Cloning
  3.3.6. Recombinational Cloning
3.4. DNA Cloning Kits
  3.4.1. PCR Cloning Kits
  3.4.2. TOPO Cloning Kits
3.5. DNA Cloning Reagents
  3.5.1. Taq Polymerase
  3.5.2. Hot-Start DNA Polymerase
  3.5.3. Processivity-Enhancing Domain
3.6. DNA Cloning Tools
  3.6.1. Advantages of Cloning tools
3.7. Challenges associated with DNA Cloning
3.8. Applications of DNA Cloning
  3.8.1. Medicinal Applications
  3.8.2. Agricultural Applications
  3.8.3. Gene Therapy
  3.8.4. Genomic Library
3.9. Future Perspectives

4. MARKET LANDSCAPE: DNA CLONING KITS

4.1. Chapter Overview
4.2. DNA Cloning Kits: Overall Market Landscape
  4.2.1 Analysis by Kit Components
  4.2.2. Analysis by Number of Reactions
  4.2.3. Analysis by Type of Cloning Method Used
  4.2.4 Analysis by Type of Fragment(s) Cloned
  4.2.5. Analysis by Cloning Time
  4.2.6. Analysis by Efficacy
  4.2.7. Analysis by Kit Shelf Life
  4.2.8. Analysis by Kit Price
4.3. DNA Cloning Kits: Developer Landscape
  4.3.1. Analysis by Year of Establishment
  4.3.2. Analysis by Company Size
  4.3.3. Analysis by Region of Headquarters
  4.3.4. Analysis by Location of Headquarters
  4.3.5. Analysis by Company Size and Region of Headquarters
  4.3.6. Leading Players: Analysis by Number of DNA Cloning Kits

5. MARKET LANDSCAPE: DNA CLONING REAGENTS

5.1. Chapter Overview
5.2. DNA Cloning Reagents: Overall Market Landscape
  5.2.1. Analysis by Unit Size
  5.2.2. Analysis by Reagent Concentration
  5.2.3. Analysis by Reagent Components
  5.2.4. Analysis by Exonuclease Activity
  5.2.5. Analysis by Product Overhangs
  5.2.6. Analysis by Heat Inactivation Temperature
  5.2.7. Analysis by Storage Temperature
  5.2.8. Analysis by Reagent Price
5.3. DNA Cloning Reagents: Developer Landscape
  5.3.1. Analysis by Year of Establishment
  5.3.2. Analysis by Company Size
  5.3.3. Analysis by Region of Headquarters
  5.3.4. Analysis by Location of Headquarters
  5.3.5. Analysis by Company Size and Region of Headquarters
  5.3.6. Leading Players: Analysis by Number of DNA Cloning Reagents

6. DNA CLONING KITS AND REAGENTS: COMPANY PROFILES

6.1. Chapter Overview
6.2. Thermo Fisher Scientific
  6.2.1. Company Overview
  6.2.2. Financial Information
  6.2.3. DNA Cloning Kit Portfolio
  6.2.4. DNA Cloning Reagent Portfolio
  6.2.5. Recent Developments and Future Outlook
6.3. Merck
  6.3.1. Company Overview
  6.3.2. Financial Information
  6.3.3. DNA Cloning Kit Portfolio
  6.3.4. DNA Cloning Reagent Portfolio
  6.3.5. Recent Developments and Future Outlook
6.4. Takara Bio
  6.4.1. Company Overview
  6.4.2. Financial Information
  6.4.3. DNA Cloning Kit Portfolio
  6.4.4. DNA Cloning Reagent Portfolio
  6.4.5. Recent Developments and Future Outlook
6.5. Vazyme
  6.5.1. Company Overview
  6.5.2. DNA Cloning Kit Portfolio
  6.5.3. Recent Developments and Future Outlook
6.6. GenScript
  6.6.1. Company Overview
  6.6.2. Financial Information
  6.6.3. DNA Cloning Kit Portfolio
  6.6.4. Recent Developments and Future Outlook
6.7. Promega
  6.7.1. Company Overview
  6.7.2. DNA Cloning Reagent Portfolio
  6.7.3. Recent Developments and Future Outlook
6.8. Agilent Technologies
  6.8.1. Company Overview
  6.8.2. Financial Information
  6.8.3. DNA Cloning Reagent Portfolio
  6.8.4. Recent Developments and Future Outlook
6.9. Bio-Rad
  6.9.1. Company Overview
  6.9.2. Financial Information
  6.9.3. DNA Cloning Reagent Portfolio
  6.9.4. Recent Developments and Future Outlook

7. PUBLICATION ANALYSIS

7.1. Chapter Overview
7.2. Scope and Methodology
  7.2.1. Analysis by Year of Publication
  7.2.2. Analysis by Type of Article
  7.2.3. Analysis by Type of Publication
  7.2.4. Word Cloud: Emerging Focus Areas
  7.2.5. Popular Publishers: Analysis by Number of Publications
  7.2.6. Popular Journals: Analysis by Number of Publications
  7.2.7. Popular Journals: Analysis of Journal Impact Factor
  7.2.8. Analysis by Geography

8. GRANT ANALYSIS

8.1. Chapter Overview
8.2. Scope and Methodology
  8.2.1. Analysis by Year of Grant Award
  8.2.2. Analysis by Amount Awarded
  8.2.3. Analysis by Administering Institute Center
  8.2.4. Analysis by Support Period
  8.2.5. Analysis by Administering Institute Center and Support Period
  8.2.6. Analysis by Type of Grant Application
  8.2.7. Analysis by Purpose of Grant
  8.2.8. Analysis by Purpose of Grant and Amount Awarded
  8.2.9. Analysis by Activity Code
  8.2.10. Analysis by Study Section Involved
  8.2.11. Word Cloud: Emerging Focus Areas
  8.2.12. Prominent Program Officers: Analysis by Number of Grants
  8.2.13. Popular Recipient Organizations: Analysis by Number of Grants
  8.2.14. Popular Recipient Organizations: Analysis by Amount Awarded
  8.2.15. Grant Analysis: Geographical Distribution of Recipient Organizations

9. PATENT ANALYSIS

9.1. Chapter Overview
9.2. Scope and Methodology
  9.2.1. Analysis by Type of Patent
  9.2.2. Analysis by Publication Year
  9.2.3. Analysis by Application Year
  9.2.4. Analysis by Geography
  9.2.5. Analysis by CPC Symbols
  9.2.6. Word Cloud: Emerging Focus Areas
  9.2.7. Analysis by Type of Organization
  9.2.8. Leading Industry Players: Analysis by Number of Patents
  9.2.9. Leading Non-Industry Players: Analysis by Number of Patents
  9.2.10. Leading Patent Assignees: Analysis by Number of Patents
  9.2.11. DNA Cloning: Patent Benchmarking Analysis
  9.2.12. Analysis by Patent Characteristics
  9.2.13. Analysis by Patent Age
  9.2.14. DNA Cloning: Patent Valuation Analysis
  9.2.15 Leading Patents by Number of Citations

10. MARKET FORECAST AND OPPORTUNITY ANALYSIS

10.1. Chapter Overview
10.2. Forecast Methodology and Key Assumptions
10.3. Global DNA Cloning Kits Market, 2022-2035
  10.3.1. DNA Cloning Kits Market, 2022- 2035: Distribution by Type of Cloning Method
    10.3.1.1. DNA Cloning Kits Market for Blunt End Cloning, 2022-2035
    10.3.1.2. DNA Cloning Kits Market for Ligase Independent Cloning, 2022-2035
    10.3.1.3. DNA Cloning Kits Market for PCR Cloning, 2022-2035
    10.3.1.4. DNA Cloning Kits Market for Seamless Cloning, 2022-2035
    10.3.1.5. DNA Cloning Kits Market for TA Cloning, 2022-2035
    10.3.1.6. DNA Cloning Kits Market for Other Methods, 2022-2035
  10.3.2 DNA Cloning Kits Market, 2022 and 2035: Distribution by End User
    10.3.2.1. DNA Cloning Kits Market for Academic and Research Institutes, 2022-2035
    10.3.2.2. DNA Cloning Kits Market for Pharmaceutical and Biotechnology Companies, 2022-2035
    10.3.2.3. DNA Cloning Kits Market for Hospitals and Clinics, 2022-2035
    10.3.2.4. DNA Cloning Kits Market for Other End-users, 2022-2035
  10.3.3. DNA Cloning Kits Market: Distribution by Key Geographical Regions, 2022-2035
    10.3.3.1. DNA Cloning Kits Market in North America, 2022-2035
    10.3.3.2. DNA Cloning Kits Market in Europe, 2022-2035
    10.3.3.3. DNA Cloning Kits Market in Asia-Pacific, 2022-2035
    10.3.3.4. DNA Cloning Kits Market in Latin America, 2022-2035
    10.3.3.5. DNA Cloning Kits Market in Middle East and North Africa, 2022-2035

11. CASE STUDY: DNA CLONING SERVICE PROVIDERS

11.1. Chapter Overview
11.2 DNA Cloning Service Providers: List of Players
  11.2.1. Analysis by Year of Establishment
  11.2.2. Analysis by Company Size
  11.2.3. Analysis by Region of Headquarters
  11.2.4. Analysis by Location of Headquarters
  11.2.5. Analysis by Company Size and Region of Headquarters

12. EVOLUTION OF DNA CLONING

12.1. Chapter Overview
12.2. Introduction of AI in Synthetic Biology
  12.2.1. Xenobots- Novel Living Machines
  12.2.2. Applications of Xenobots
  12.2.3. Ethical Issues
  12.2.4. Future of Xenobots
12.3. Conclusion

13. CONCLUDING REMARKS

14. EXECUTIVE INSIGHTS

14.1. Chapter Overview
14.2. SBS Genetech
  14.2.1. Company Snapshot
  14.2.2. Interview Transcript
14.3. Canvax Biotech
  14.3.1. Company Snapshot
  14.3.2. Interview Transcript: Jesъs C. Morales, Business Development Manager

15. APPENDIX 1: TABULATED DATA

16. APPENDIX 2: LIST OF COMPANIES AND ORGANIZATIONS


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