DNA-encoded Library Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Product & Service (Kits & Reagents, Encoded Libraries, Design & Synthesis Services, Screening Services, Others), By Therapeutic Area (Oncology, Infectious Diseases, Cardiovascular Diseases, Neurological Diseases, Autoimmune Diseases, Metabolic Diseases, Others), By Application (Hit Generation / Identification, Hit to Lead, Hit Validation / Optimization, Others), By End Use (Academic & Research Institutes, Pharmaceutical & Biotechnology Companies, Contract Research Organizations, Others), By Region and Competition, 2020-2030F

May 2025 | 186 pages | ID: DF6EDBBD2862EN
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Market Overview

The Global DNA-encoded Library (DEL) Market was valued at USD 762.08 Million in 2024 and is projected to reach USD 1632.26 Million by 2030, growing at a CAGR of 13.51%. DEL technology is revolutionizing early-stage drug discovery by enabling simultaneous screening of billions of compounds, which enhances efficiency and accelerates hit identification. As pharmaceutical and biotech companies seek scalable, cost-effective platforms for bioactive molecule discovery, DELs are gaining traction due to their high-throughput capabilities and chemical diversity. Increased R&D investment, growing interest in personalized medicine, and the demand for faster therapeutic development continue to drive adoption. Integration of artificial intelligence and machine learning into DEL workflows further enhances compound analysis, lead selection, and predictive modeling. With technological innovations in encoding chemistries and compound scaffolds, and the emergence of hybrid screening strategies, the DEL market is poised for continued robust growth.

Key Market Drivers

Rising Demand for Efficient Drug Discovery Methods

The surge in demand for efficient drug discovery methods is a major factor driving the growth of the DEL market. Traditional drug discovery involves extensive time and financial investment, often with low success rates. DELs address this issue by enabling the rapid screening of billions of small molecules tagged with unique DNA barcodes, allowing researchers to identify promising interactions with target proteins more effectively. This method significantly reduces the time and cost associated with early-stage drug development. As pharmaceutical companies aim to speed up the development of targeted therapies for complex conditions such as cancer and neurological disorders, the scalability and precision of DEL technology offer a compelling advantage. The ability to explore vast chemical spaces and develop tailored treatments aligns with the industry's shift toward precision medicine, reinforcing DEL’s role as a vital tool in modern drug discovery.

Key Market Challenges

Complexity of Library Design and Synthesis

The intricate process of designing and synthesizing DNA-encoded libraries presents a key challenge to market growth. Creating diverse libraries requires specialized expertise in conjugating small molecules with DNA tags, with multiple synthesis steps that must be precisely executed. Maintaining the fidelity and reproducibility of libraries across large datasets is a technical hurdle, as errors in encoding can lead to inaccurate screening outcomes. Additionally, balancing chemical diversity with biological compatibility limits the scope of compound design. Some complex molecules or desired modifications may be difficult to synthesize or require extensive refinement, increasing time and costs. These complexities affect consistency and scalability, especially during transition from discovery to lead optimization.

Key Market Trends

Increasing Adoption of High-Throughput Screening Technologies

High-throughput screening (HTS) technologies are becoming increasingly integrated with DEL platforms, enabling rapid evaluation of millions to billions of compounds. This combination boosts drug discovery efficiency by reducing time and cost while increasing hit identification accuracy. Advances in automation, robotics, and data analytics are optimizing HTS workflows, making them more adaptable to DEL applications. Artificial intelligence and machine learning algorithms are further enhancing analysis by improving target interaction predictions and prioritizing hits. These capabilities are essential in the discovery of novel therapeutics for oncology, infectious diseases, and neurological disorders, fueling broader market adoption.

Key Market Players

  • Merck KGaA
  • GenScript Biotech Corporation
  • Pharmaron Beijing Co., Ltd.
  • WuXi AppTec Co., Ltd.
  • Aurigene Pharmaceutical Services Limited
  • BOC Sciences
  • LGC Bioresearch Technologies
  • SPT Labtech Ltd.
  • Charles River Laboratories International, Inc.
  • Life Chemicals Inc.


Report Scope

In this report, the Global DNA-encoded Library Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

  • DNA-encoded Library Market, By Product & Service:
    • Kits & Reagents
    • Encoded Libraries
    • Design & Synthesis Services
    • Screening Services
    • Others
  • DNA-encoded Library Market, By Therapeutic Area:
    • Oncology
    • Infectious Diseases
    • Cardiovascular Diseases
    • Neurological Diseases
    • Autoimmune Diseases
    • Metabolic Diseases
    • Others
  • DNA-encoded Library Market, By Application:
    • Hit Generation / Identification
    • Hit to Lead
    • Hit Validation / Optimization
    • Others
  • DNA-encoded Library Market, By End Use:
    • Academic & Research Institutes
    • Pharmaceutical & Biotechnology Companies
    • Contract Research Organizations
    • Others
  • DNA-encoded Library Market, By Region:
    • North America
      • United States
      • Canada
      • Mexico
    • Europe
      • France
      • United Kingdom
      • Italy
      • Germany
      • Spain
    • Asia-Pacific
      • China
      • India
      • Japan
      • Australia
      • South Korea
    • South America
      • Brazil
      • Argentina
      • Colombia
    • Middle East & Africa
      • South Africa
      • Saudi Arabia
      • UAE


Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the Global DNA-encoded Library Market.

Available Customizations

Global DNA-encoded Library Market report with the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report:

Company Information

  • Detailed analysis and profiling of additional market players (up to five).

1. PRODUCT OVERVIEW

1.1. Market Definition
1.2. Scope of the Market
  1.2.1. Markets Covered
  1.2.2. Years Considered for Study
  1.2.3. Key Market Segmentations

2. RESEARCH METHODOLOGY

2.1. Objective of the Study
2.2. Baseline Methodology
2.3. Key Industry Partners
2.4. Major Association and Secondary Sources
2.5. Forecasting Methodology
2.6. Data Triangulation & Validation
2.7. Assumptions and Limitations

3. EXECUTIVE SUMMARY

3.1. Overview of the Market
3.2. Overview of Key Market Segmentations
3.3. Overview of Key Market Players
3.4. Overview of Key Regions/Countries
3.5. Overview of Market Drivers, Challenges, and Trends

4. VOICE OF CUSTOMER

5. GLOBAL DNA-ENCODED LIBRARY MARKET OUTLOOK

5.1. Market Size & Forecast
  5.1.1. By Value
5.2. Market Share & Forecast
  5.2.1. By Product & Service (Kits & Reagents, Encoded Libraries, Design & Synthesis Services, Screening Services, Others)
  5.2.2. By Therapeutic Area (Oncology, Infectious Diseases, Cardiovascular Diseases, Neurological Diseases, Autoimmune Diseases, Metabolic Diseases, Others)
  5.2.3. By Application (Hit Generation / Identification, Hit to Lead, Hit Validation / Optimization, Others)
  5.2.4. By End Use (Academic & Research Institutes, Pharmaceutical & Biotechnology Companies, Contract Research Organizations, Others)
  5.2.5. By Company (2024)
  5.2.6. By Region
5.3. Market Map

6. NORTH AMERICA DNA-ENCODED LIBRARY MARKET OUTLOOK

6.1. Market Size & Forecast
  6.1.1. By Value
6.2. Market Share & Forecast
  6.2.1. By Product & Service
  6.2.2. By Therapeutic Area
  6.2.3. By Application
  6.2.4. By End Use
  6.2.5. By Country
6.3. North America: Country Analysis
  6.3.1. United States DNA-encoded Library Market Outlook
    6.3.1.1. Market Size & Forecast
      6.3.1.1.1. By Value
    6.3.1.2. Market Share & Forecast
      6.3.1.2.1. By Product & Service
      6.3.1.2.2. By Therapeutic Area
      6.3.1.2.3. By Application
      6.3.1.2.4. By End Use
  6.3.2. Mexico DNA-encoded Library Market Outlook
    6.3.2.1. Market Size & Forecast
      6.3.2.1.1. By Value
    6.3.2.2. Market Share & Forecast
      6.3.2.2.1. By Product & Service
      6.3.2.2.2. By Therapeutic Area
      6.3.2.2.3. By Application
      6.3.2.2.4. By End Use
  6.3.3. Canada DNA-encoded Library Market Outlook
    6.3.3.1. Market Size & Forecast
      6.3.3.1.1. By Value
    6.3.3.2. Market Share & Forecast
      6.3.3.2.1. By Product & Service
      6.3.3.2.2. By Therapeutic Area
      6.3.3.2.3. By Application
      6.3.3.2.4. By End Use

7. EUROPE DNA-ENCODED LIBRARY MARKET OUTLOOK

7.1. Market Size & Forecast
  7.1.1. By Value
7.2. Market Share & Forecast
  7.2.1. By Product & Service
  7.2.2. By Therapeutic Area
  7.2.3. By Application
  7.2.4. By End Use
  7.2.5. By Country
7.3. Europe: Country Analysis
  7.3.1. France DNA-encoded Library Market Outlook
    7.3.1.1. Market Size & Forecast
      7.3.1.1.1. By Value
    7.3.1.2. Market Share & Forecast
      7.3.1.2.1. By Product & Service
      7.3.1.2.2. By Therapeutic Area
      7.3.1.2.3. By Application
      7.3.1.2.4. By End Use
  7.3.2. Germany DNA-encoded Library Market Outlook
    7.3.2.1. Market Size & Forecast
      7.3.2.1.1. By Value
    7.3.2.2. Market Share & Forecast
      7.3.2.2.1. By Product & Service
      7.3.2.2.2. By Therapeutic Area
      7.3.2.2.3. By Application
      7.3.2.2.4. By End Use
  7.3.3. United Kingdom DNA-encoded Library Market Outlook
    7.3.3.1. Market Size & Forecast
      7.3.3.1.1. By Value
    7.3.3.2. Market Share & Forecast
      7.3.3.2.1. By Product & Service
      7.3.3.2.2. By Therapeutic Area
      7.3.3.2.3. By Application
      7.3.3.2.4. By End Use
  7.3.4. Italy DNA-encoded Library Market Outlook
    7.3.4.1. Market Size & Forecast
      7.3.4.1.1. By Value
    7.3.4.2. Market Share & Forecast
      7.3.4.2.1. By Product & Service
      7.3.4.2.2. By Therapeutic Area
      7.3.4.2.3. By Application
      7.3.4.2.4. By End Use
  7.3.5. Spain DNA-encoded Library Market Outlook
    7.3.5.1. Market Size & Forecast
      7.3.5.1.1. By Value
    7.3.5.2. Market Share & Forecast
      7.3.5.2.1. By Product & Service
      7.3.5.2.2. By Therapeutic Area
      7.3.5.2.3. By Application
      7.3.5.2.4. By End Use

8. ASIA-PACIFIC DNA-ENCODED LIBRARY MARKET OUTLOOK

8.1. Market Size & Forecast
  8.1.1. By Value
8.2. Market Share & Forecast
  8.2.1. By Product & Service
  8.2.2. By Therapeutic Area
  8.2.3. By Application
  8.2.4. By End Use
  8.2.5. By Country
8.3. Asia-Pacific: Country Analysis
  8.3.1. China DNA-encoded Library Market Outlook
    8.3.1.1. Market Size & Forecast
      8.3.1.1.1. By Value
    8.3.1.2. Market Share & Forecast
      8.3.1.2.1. By Product & Service
      8.3.1.2.2. By Therapeutic Area
      8.3.1.2.3. By Application
      8.3.1.2.4. By End Use
  8.3.2. India DNA-encoded Library Market Outlook
    8.3.2.1. Market Size & Forecast
      8.3.2.1.1. By Value
    8.3.2.2. Market Share & Forecast
      8.3.2.2.1. By Product & Service
      8.3.2.2.2. By Therapeutic Area
      8.3.2.2.3. By Application
      8.3.2.2.4. By End Use
  8.3.3. South Korea DNA-encoded Library Market Outlook
    8.3.3.1. Market Size & Forecast
      8.3.3.1.1. By Value
    8.3.3.2. Market Share & Forecast
      8.3.3.2.1. By Product & Service
      8.3.3.2.2. By Therapeutic Area
      8.3.3.2.3. By Application
      8.3.3.2.4. By End Use
  8.3.4. Japan DNA-encoded Library Market Outlook
    8.3.4.1. Market Size & Forecast
      8.3.4.1.1. By Value
    8.3.4.2. Market Share & Forecast
      8.3.4.2.1. By Product & Service
      8.3.4.2.2. By Therapeutic Area
      8.3.4.2.3. By Application
      8.3.4.2.4. By End Use
  8.3.5. Australia DNA-encoded Library Market Outlook
    8.3.5.1. Market Size & Forecast
      8.3.5.1.1. By Value
    8.3.5.2. Market Share & Forecast
      8.3.5.2.1. By Product & Service
      8.3.5.2.2. By Therapeutic Area
      8.3.5.2.3. By Application
      8.3.5.2.4. By End Use

9. SOUTH AMERICA DNA-ENCODED LIBRARY MARKET OUTLOOK

9.1. Market Size & Forecast
  9.1.1. By Value
9.2. Market Share & Forecast
  9.2.1. By Product & Service
  9.2.2. By Therapeutic Area
  9.2.3. By Application
  9.2.4. By End Use
  9.2.5. By Country
9.3. South America: Country Analysis
  9.3.1. Brazil DNA-encoded Library Market Outlook
    9.3.1.1. Market Size & Forecast
      9.3.1.1.1. By Value
    9.3.1.2. Market Share & Forecast
      9.3.1.2.1. By Product & Service
      9.3.1.2.2. By Therapeutic Area
      9.3.1.2.3. By Application
      9.3.1.2.4. By End Use
  9.3.2. Argentina DNA-encoded Library Market Outlook
    9.3.2.1. Market Size & Forecast
      9.3.2.1.1. By Value
    9.3.2.2. Market Share & Forecast
      9.3.2.2.1. By Product & Service
      9.3.2.2.2. By Therapeutic Area
      9.3.2.2.3. By Application
      9.3.2.2.4. By End Use
  9.3.3. Colombia DNA-encoded Library Market Outlook
    9.3.3.1. Market Size & Forecast
      9.3.3.1.1. By Value
    9.3.3.2. Market Share & Forecast
      9.3.3.2.1. By Product & Service
      9.3.3.2.2. By Therapeutic Area
      9.3.3.2.3. By Application
      9.3.3.2.4. By End Use

10. MIDDLE EAST AND AFRICA DNA-ENCODED LIBRARY MARKET OUTLOOK

10.1. Market Size & Forecast
  10.1.1. By Value
10.2. Market Share & Forecast
  10.2.1. By Product & Service
  10.2.2. By Therapeutic Area
  10.2.3. By Application
  10.2.4. By End Use
  10.2.5. By Country
10.3. MEA: Country Analysis
  10.3.1. South Africa DNA-encoded Library Market Outlook
    10.3.1.1. Market Size & Forecast
      10.3.1.1.1. By Value
    10.3.1.2. Market Share & Forecast
      10.3.1.2.1. By Product & Service
      10.3.1.2.2. By Therapeutic Area
      10.3.1.2.3. By Application
      10.3.1.2.4. By End Use
  10.3.2. Saudi Arabia DNA-encoded Library Market Outlook
    10.3.2.1. Market Size & Forecast
      10.3.2.1.1. By Value
    10.3.2.2. Market Share & Forecast
      10.3.2.2.1. By Product & Service
      10.3.2.2.2. By Therapeutic Area
      10.3.2.2.3. By Application
      10.3.2.2.4. By End Use
  10.3.3. UAE DNA-encoded Library Market Outlook
    10.3.3.1. Market Size & Forecast
      10.3.3.1.1. By Value
    10.3.3.2. Market Share & Forecast
      10.3.3.2.1. By Product & Service
      10.3.3.2.2. By Therapeutic Area
      10.3.3.2.3. By Application
      10.3.3.2.4. By End Use

11. MARKET DYNAMICS

11.1. Drivers
11.2. Challenges

12. MARKET TRENDS & DEVELOPMENTS

12.1. Merger & Acquisition (If Any)
12.2. Product Launches (If Any)
12.3. Recent Developments

13. PORTERS FIVE FORCES ANALYSIS

13.1. Competition in the Industry
13.2. Potential of New Entrants
13.3. Power of Suppliers
13.4. Power of Customers
13.5. Threat of Substitute Products

14. COMPETITIVE LANDSCAPE

14.1. Merck KGaA
  14.1.1. Business Overview
  14.1.2. Company Snapshot
  14.1.3. Products & Services
  14.1.4. Financials (As Reported)
  14.1.5. Recent Developments
  14.1.6. Key Personnel Details
  14.1.7. SWOT Analysis
14.2. GenScript Biotech Corporation
14.3. Pharmaron Beijing Co., Ltd.
14.4. WuXi AppTec Co., Ltd.
14.5. Aurigene Pharmaceutical Services Limited
14.6. BOC Sciences
14.7. LGC Bioresearch Technologies
14.8. SPT Labtech Ltd.
14.9. Charles River Laboratories International, Inc.
14.10. Life Chemicals Inc.

15. STRATEGIC RECOMMENDATIONS

16. ABOUT US & DISCLAIMER


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