Epigenetics - Global Market Outlook (2017-2023)

November 2017 | 156 pages | ID: EE22EF6760BEN
Stratistics Market Research Consulting

Abstracts

According to Stratistics MRC,the Global Epigenetics Market is accounted for $752.8 million in 2016 and expected to grow at a CAGR of 14.0% to reach $1891.9 million by 2023. Growing prevalence of cancer and other chronic diseases are helping the market to compete across the globe. Some of the major factors that are influencing the market include growing technological advancements, rising R&D expenditure, growing usage for non-oncology diseases, improving collaborations between pharmaceutical, biotechnology companies & academic research institutes and increasing geriatric population base. However, huge equipment cost, lack of predictive markers, inefficiency in identification and validation of biomarkers, presence of complicated regulatory framework and shortage of skilled professional are hampering the market growth.

Based on Technology, DNA methylation can be classified as hyper and hypomethylation. Reduced representation bisulfite sequencing (RRBS) is a DNA wide methylation analysis technique for a combination of enrichment and modifying techniques. DNA methylation is also used as a biomarker for early cancer diagnosis. The FDA-approved epigenetic drugs are demethylating agents, and most of the diagnostic activity to date in epigenetics has focused on methylation markers.

Based on End User, with in the pharmaceutical sector, the therapeutic applications of epigenetics have fascinated a large and growing number of pharmaceutical and biopharmaceutical companies. Over 40 companies that are now active. Venture capital-funded companies in epigenetics include Constellation Pharmaceuticals and Syndax Pharmaceuticals.

North America dominated the overall revenue, due to the, increasing funds for R&D, growing collaborations between large pharmaceutical firms and demand for epigenetic drugs and diagnostic technologies. However, Asia-Pacific is anticipated to grow rapidly, due to high incidence of cancer, large prevalence of target diseases and rise in healthcare expenditure.

Some of the key players in Global Epigenetics market are Celgene Corporation, CellCentric Ltd, Chroma Therapeutics Ltd, Covaris Inc, DIAGENODE, INC., Ribimed Biotechnologies, Epigenomics AG, Epitherapeutics, Epizyme, Karus Therapeutics, Merck Millipore, Novartis International AG, Oncolys Biopharma Inc, OncoMethylome Sciences, Qiagen, Sigma-Aldrich Corporation, Syndax Pharmaceuticals and ZYMO RESEARCH CORPORATION (ZYMO).

Products Covered:

• Enzymes
• Reagents
• Kits
• Instruments and Consumables

Technologies Covered:

• Histone Methylation
• DNA Methylation
• Histone Acetylation
• Large noncoding RNA
• Chromatin structures
• MicroRNA Modification
• Other Technologies

Applications Covered:

• Cardiovascular Diseases
• Developmental Biology
• Immunology
• Metabolic Diseases
• Inflammatory Disease
• Oncology
• Other Applications

End Users Covered:

• Pharmaceutical
• Contract Research Organizations
• Academic and Research Institutes
• Biotechnology Companies

Regions Covered:

• North America
• US
• Canada
• Mexico
• Europe
• Germany
• UK
• Italy
• France
• Spain
• Rest of Europe
• Asia Pacific
• Japan
• China
• India
• Australia
• New Zealand
• South Korea
• Rest of Asia Pacific
• South America
• Argentina
• Brazil
• Chile
• Rest of South America
• Middle East & Africa
• Saudi Arabia
• UAE
• Qatar
• South Africa
• Rest of Middle East & Africa

What our report offers:

• Market share assessments for the regional and country level segments
• Market share analysis of the top industry players
• Strategic recommendations for the new entrants
• Market forecasts for a minimum of 7 years of all the mentioned segments, sub segments and the regional markets
• Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations)
• Strategic recommendations in key business segments based on the market estimations
• Competitive landscaping mapping the key common trends
• Company profiling with detailed strategies, financials, and recent developments
• Supply chain trends mapping the latest technological advancements

Contents

1 EXECUTIVE SUMMARY

2 PREFACE

2.1 Abstract
2.2 Stake Holders
2.3 Research Scope
2.4 Research Methodology
  2.4.1 Data Mining
  2.4.2 Data Analysis
  2.4.3 Data Validation
  2.4.4 Research Approach
2.5 Research Sources
  2.5.1 Primary Research Sources
  2.5.2 Secondary Research Sources
  2.5.3 Assumptions

3 MARKET TREND ANALYSIS

3.1 Introduction
3.2 Drivers
3.3 Restraints
3.4 Opportunities
3.5 Threats
3.6 Technology Analysis
3.7 Product Analysis
3.8 Application Analysis
3.9 End User Analysis
3.10 Emerging Markets
3.11 Futuristic Market Scenario

4 PORTERS FIVE FORCE ANALYSIS

4.1 Bargaining power of suppliers
4.2 Bargaining power of buyers
4.3 Threat of substitutes
4.4 Threat of new entrants
4.5 Competitive rivalry

5 GLOBAL EPIGENETICS MARKET, BY PRODUCT

5.1 Introduction
5.2 Enzymes
  5.2.1 RNA-Modifying Enzymes
    5.2.1.1 Reverse Transcriptase
    5.2.1.2 RNA Ligases
    5.2.1.2 Other RNA-modifying Enzymes
  5.2.2 Protein-Modifying Enzymes
    5.2.2.1 Acetylases
    5.2.2.2 Methyltransferases
  5.2.3 DNA-Modifying Enzymes
    5.2.3.1 DNA Ligases
    5.2.3.2 DNA Polymerases
5.3 Reagents
  5.3.1 Primers
  5.3.2 Magnetic Beads
  5.3.3 Histones
  5.3.4 Buffers
  5.3.5 Antibodies
  5.3.6 Other Epigenetics Reagents
5.4 Kits
  5.4.1 5-HMC and 5-MC Analysis Kits
  5.4.2 Bisulfite Conversion Kits
  5.4.3 Chip-Seq Kits
  5.4.4 RNA Sequencing Kits
  5.4.5 Whole-Genome Amplification Kits
  5.4.6 Methyltransferase assays
  5.4.7 Histone Assays
  5.4.8 Immunoprecipitation Kits
  5.4.9 Other Epigenetics Kits
5.5 Instruments and Consumables
  5.5.1 Mass Spectrometers
  5.5.2 Next-Generation Sequencers
  5.5.3 Qpcr Instruments
  5.5.4 Sonicators
  5.5.5 Other Instruments and Consumables

6 GLOBAL EPIGENETICS MARKET, BY TECHNOLOGY

6.1 Introduction
6.2 Histone Methylation
6.3 DNA Methylation
6.4 Histone Acetylation
6.5 Large noncoding RNA
6.6 Chromatin structures
6.7 MicroRNA Modification
6.8 Other Technologies

7 GLOBAL EPIGENETICS MARKET, BY APPLICATION

7.1 Introduction
7.2 Cardiovascular Diseases
7.3 Developmental Biology
7.4 Immunology
7.5 Metabolic Diseases
7.6 Inflammatory Disease
7.7 Oncology
  7.7.1 Liquid Tumor
  7.7.2 Solid Tumor
7.8 Other Applications

8 GLOBAL EPIGENETICS MARKET, BY END USER

8.1 Introduction
8.2 Pharmaceutical
8.3 Contract Research Organizations
8.4 Academic and Research Institutes
8.5 Biotechnology Companies

9 GLOBAL EPIGENETICS MARKET, BY GEOGRAPHY

9.1 Introduction
9.2 North America
  9.2.1 US
  9.2.2 Canada
  9.2.3 Mexico
9.3 Europe
  9.3.1 Germany
  9.3.2 UK
  9.3.3 Italy
  9.3.4 France
  9.3.5 Spain
  9.3.6 Rest of Europe
9.4 Asia Pacific
  9.4.1 Japan
  9.4.2 China
  9.4.3 India
  9.4.4 Australia
  9.4.5 New Zealand
  9.4.6 South Korea
  9.4.7 Rest of Asia Pacific
9.5 South America
  9.5.1 Argentina
  9.5.2 Brazil
  9.5.3 Chile
  9.5.4 Rest of South America
9.6 Middle East & Africa
  9.6.1 Saudi Arabia
  9.6.2 UAE
  9.6.3 Qatar
  9.6.4 South Africa
  9.6.5 Rest of Middle East & Africa

10 KEY DEVELOPMENTS

10.1 Agreements, Partnerships, Collaborations and Joint Ventures
10.2 Acquisitions & Mergers
10.3 New Product Launch
10.4 Expansions
10.5 Other Key Strategies

11 COMPANY PROFILING

11.1 Celgene Corporation
11.2 CellCentric Ltd
11.3 Chroma Therapeutics Ltd,
11.4 Covaris Inc
11.5 DIAGENODE, INC.
11.6 Ribimed Biotechnologies
11.7 Epigenomics AG
11.8 Epitherapeutics
11.9 Epizyme
11.10 Karus Therapeutics
11.11 Merck Millipore
11.12 Novartis International AG
11.13 Oncolys Biopharma Inc
11.14 OncoMethylome Sciences
11.15 Qiagen
11.16 Sigma-Aldrich Corporation
11.17 Syndax Pharmaceuticals
11.18 ZYMO RESEARCH CORPORATION (ZYMO)

List Of Tables

LIST OF TABLES

Table 1 Global Epigenetics Market Outlook, By Region (2014-2023) ($MN)
Table 2 Global Epigenetics Market Outlook, By Product (2014-2023) ($MN)
Table 3 Global Epigenetics Market Outlook, By Enzymes (2014-2023) ($MN)
Table 4 Global Epigenetics Market Outlook, By RNA-Modifying Enzymes (2014-2023) ($MN)
Table 5 Global Epigenetics Market Outlook, By Protein-Modifying Enzymes (2014-2023) ($MN)
Table 6 Global Epigenetics Market Outlook, By DNA-Modifying Enzymes (2014-2023) ($MN)
Table 7 Global Epigenetics Market Outlook, By Reagents (2014-2023) ($MN)
Table 8 Global Epigenetics Market Outlook, By Primers (2014-2023) ($MN)
Table 9 Global Epigenetics Market Outlook, By Magnetic Beads (2014-2023) ($MN)
Table 10 Global Epigenetics Market Outlook, By Histones (2014-2023) ($MN)
Table 11 Global Epigenetics Market Outlook, By Buffers (2014-2023) ($MN)
Table 12 Global Epigenetics Market Outlook, By Antibodies (2014-2023) ($MN)
Table 13 Global Epigenetics Market Outlook, By Other Epigenetics Reagents (2014-2023) ($MN)
Table 14 Global Epigenetics Market Outlook, By Kits (2014-2023) ($MN)
Table 15 Global Epigenetics Market Outlook, By 5-HMC and 5-MC Analysis Kits (2014-2023) ($MN)
Table 16 Global Epigenetics Market Outlook, By Bisulfite Conversion Kits (2014-2023) ($MN)
Table 17 Global Epigenetics Market Outlook, By Chip-Seq Kits (2014-2023) ($MN)
Table 18 Global Epigenetics Market Outlook, By RNA Sequencing Kits (2014-2023) ($MN)
Table 19 Global Epigenetics Market Outlook, By Whole-Genome Amplification Kits (2014-2023) ($MN)
Table 20 Global Epigenetics Market Outlook, By Methyltransferase assays (2014-2023) ($MN)
Table 21 Global Epigenetics Market Outlook, By Histone Assays (2014-2023) ($MN)
Table 22 Global Epigenetics Market Outlook, By Immunoprecipitation Kits (2014-2023) ($MN)
Table 23 Global Epigenetics Market Outlook, By Other Epigenetics Kits (2014-2023) ($MN)
Table 24 Global Epigenetics Market Outlook, By Instruments and Consumables (2014-2023) ($MN)
Table 25 Global Epigenetics Market Outlook, By Mass Spectrometers (2014-2023) ($MN)
Table 26 Global Epigenetics Market Outlook, By Next-Generation Sequencers (2014-2023) ($MN)
Table 27 Global Epigenetics Market Outlook, By Qpcr Instruments (2014-2023) ($MN)
Table 28 Global Epigenetics Market Outlook, By Sonicators (2014-2023) ($MN)
Table 29 Global Epigenetics Market Outlook, By Other Instruments and Consumables (2014-2023) ($MN)
Table 30 Global Epigenetics Market Outlook, By Technology (2014-2023) ($MN)
Table 31 Global Epigenetics Market Outlook, By Histone Methylation (2014-2023) ($MN)
Table 32 Global Epigenetics Market Outlook, By DNA Methylation (2014-2023) ($MN)
Table 33 Global Epigenetics Market Outlook, By Histone Acetylation (2014-2023) ($MN)
Table 34 Global Epigenetics Market Outlook, By Large noncoding RNA (2014-2023) ($MN)
Table 35 Global Epigenetics Market Outlook, By Chromatin structures (2014-2023) ($MN)
Table 36 Global Epigenetics Market Outlook, By MicroRNA Modification (2014-2023) ($MN)
Table 37 Global Epigenetics Market Outlook, By Other Technologies (2014-2023) ($MN)
Table 38 Global Epigenetics Market Outlook, By Application (2014-2023) ($MN)
Table 39 Global Epigenetics Market Outlook, By Cardiovascular Diseases (2014-2023) ($MN)
Table 40 Global Epigenetics Market Outlook, By Developmental Biology (2014-2023) ($MN)
Table 41 Global Epigenetics Market Outlook, By Immunology (2014-2023) ($MN)
Table 42 Global Epigenetics Market Outlook, By Metabolic Diseases (2014-2023) ($MN)
Table 43 Global Epigenetics Market Outlook, By Inflammatory Disease (2014-2023) ($MN)
Table 44 Global Epigenetics Market Outlook, By Oncology (2014-2023) ($MN)
Table 45 Global Epigenetics Market Outlook, By Liquid Tumor (2014-2023) ($MN)
Table 46 Global Epigenetics Market Outlook, By Solid Tumor (2014-2023) ($MN)
Table 47 Global Epigenetics Market Outlook, By Other Applications (2014-2023) ($MN)
Table 48 Global Epigenetics Market Outlook, By End User (2014-2023) ($MN)
Table 49 Global Epigenetics Market Outlook, By Pharmaceutical (2014-2023) ($MN)
Table 50 Global Epigenetics Market Outlook, By Contract Research Organizations (2014-2023) ($MN)
Table 51 Global Epigenetics Market Outlook, By Academic and Research Institutes (2014-2023) ($MN)
Table 52 Global Epigenetics Market Outlook, By Biotechnology Companies (2014-2023) ($MN)

Note: North America, Europe, Asia Pacific, South America and Middle East are represented in above manner.