The Chinese Market for DNA Sequencing

May 2018 | 171 pages | ID: C5C70A160D1EN
BCC Research

Abstracts

REPORT SCOPE:

The scope of the report includes sequencing technologies, applications, industries, initiatives, markets and companies in China. The markets for sequencing products and services are given for 2016, 2017 and 2022.

This report covers the Chinese sequencing market by workflow, including sample preparation products, sequencing instruments and consumables, informatics and sequencing services. It includes the Chinese sequencing instrument market by platform (i.e., Sanger and next-generation technologies) and by instrument class (i.e., low-throughput, high-throughput, benchtop, handheld).

In this report, “China” refers to Mainland China. This does not include Hong Kong, Macao and Taiwan. Mainland China has a total of 31 province-level regions, including 22 provinces, four province-level municipalities (cities) and five province-level autonomous regions. Important regional markets will be discussed, including Beijing, Shanghai and Guangdong.

More than 100 Chinese companies in the sequencing industry are profiled in this report.

REPORT INCLUDES:

• 91 tables
• An in-depth analysis of the Chinese DNA sequencing market, an important sector in life sciences with enormous market potential
• Analyses of market trends, with data from 2016 and 2017, and projections of compound annual growth rates (CAGRs) through 2022
• Quantification of the DNA sequencing market by product type, platform, customer type, value chain position, analysis type, and region
• A look at the substantial growth opportunities for industry participants, including consumer and diagnostic sequencing services, bioinformatics, sequence enrichment, benchtop NGS sequencers and consumables, and emerging sequencing instruments
• Comprehensive discussion covering sequencing technologies, market applications, industry structure, and important clinical sequencing initiatives
• Company profiles of major Chinese companies in the sequencing industry, including Gene Denovo, IGE Biotechnology Ltd., Pacific Biosciences, Beijing Genomics Institute (BGI), and Adicon Clinical Laboratories, Inc.

EXECUTIVE SUMMARY

Since the previous edition of this report published in September 2016, the Chinese DNA sequencing market has had many significant developments, including:

• Revenues of leading companies maintained fast growth through mid-2018. This indicates the high growth rate (i.e., a CAGR of REDACTED). BCC Research forecast in the previous edition of thisreport that this growth rate was likely to continue.
• On October 27, 2016, the Chinese government removed restrictions on NIPT services. Any medical body qualified for prenatal examination in China is now allowed to do NIPT without additional governmental approval. This removed the main obstacle to the Chinese NIPT sequencing market.
• The number of newly-established sequencing companies in 2016 and 2017 was smaller than in 2014 and 2015. New entrants had less opportunity while older players led the market.
• Companies founded in 2014 and 2015 received funding from angel investment and series of A/B rounds. Investors from both inside and outside China showed their great interest in the fastgrowing Chinese DNA sequencing market because the earnings outlook has become clearer than before. More than $1 billion was invested in burgeoning Chinese sequencing companies in 2017. Some of the older players closed or moved to other services. Market opportunity always comes with risks.
• Large sequencing service providers are developing their own equipment, whereas equipment distributors are beginning to provide sequencing services. The upstream and downstream industries interact and intertwine with one another.
• When NovaSeq launched in early 2017, Novogene decided to buy 25 sets of NovaSeq machines. With three sets of HiSeq X Ten and the Novogene sequencers, Novogene currently leads the game of instrument investment in China. As a result, Novogene strengthens its leading position in the sequencing service market, especially in the R&D service market.
• Sequencing companies from major cities such as Beijing, Shanghai and Shenzhen, where the Chinese DNA sequencing industry begun, are now penetrating other Chinese cities. Tianjin, Chengdu and Chongqing have shown significant potential for strong growth.
• Cooperation, acquisitions and mergers are changing the image of the industry, thus increasing competition while producing new opportunities to industry players.

This chapter provides a summary of the Chinese DNA sequencing market. It also discusses the largest and the fastest-growing markets and important governmental targets and regulations.

The Chinese sequencing industry experienced significant changes as the market grew in recent years. When the industry started in China before 2010, demand from government-sponsored R&D projectswas its main driving force. In 2010, noninvasive prenatal testing (NIPT) came to the market, starting the fast growth of the clinical application segment in the following three years. The NIPT service, however, was interrupted by the government in early 2014. In mid-2014, the government only approved a few companies for providing NIPT services to the Chinese market.

Contents

CHAPTER 1 INTRODUCTION

Study Goals and Objectives
Reasons for Doing This Study
Scope of Report
Intended Audience
Information Sources
Methodology
Regional Breakdown
Analysts' Credentials
Related BCC Research Reports

CHAPTER 2 SUMMARY AND HIGHLIGHTS

Market Highlights
Largest Markets
Fastest-growing Markets
Regulations and Targets
Precision Medicine
End of One-Child Policy
End of NIPT Limitation

CHAPTER 3 CHINESE SEQUENCING MARKET

Overview
Industry Details
Brief History
Regions and Provinces
Driving Forces
Investment
Pre- and Post-sequencing Products
Sequencing Sample Prep Market by Application
Sequencing Informatics by Software Function
Sequencing Instruments and Consumables
Sequencing Instrument and Consumable Market by Product Type
Sequencing Instruments and Consumables by Platform
Sequencing Instruments and Consumables by Instrument Class
Sequencing Services Market
Clinical Application
Research and Development Application
Applied Application
Clinical Sequencing Service Market
Sequencing Service Market by Genome Type

CHAPTER 4 GUANGDONG SEQUENCING MARKET

Overview
Industry Details
Driving Forces
Pre- and Post-Sequencing Products
Sequencing Sample Prep Market by Application
Sequencing Informatics by Software Function
Sequencing Instruments and Consumables
Sequencing Instrument and Consumable Market by Product Type
Sequencing Instruments and Consumables by Platform
Sequencing Instruments and Consumables by Instrument Class
Sequencing Services Market
Clinical Sequencing Service Market
Applied Sequencing Services Market

CHAPTER 5 BEIJING SEQUENCING MARKET

Overview
Industry Details
Driving Forces
Pre- and Post-Sequencing Products
Sequencing Sample Prep Market by Application
Sequencing Informatics by Software Function
Sequencing Instruments and Consumables
Sequencing Instruments and Consumables Market by Product Type
Sequencing Instruments and Consumables by Platform
Sequencing Instruments and Consumables by Instrument Class
Sequencing Service Market
Clinical Sequencing Service Market
Applied Sequencing Services Market

CHAPTER 6 SHANGHAI SEQUENCING MARKET

Overview
Industry Details
Driving Forces
Pre- and Post-Sequencing Products
Sequencing Sample Prep Market by Application
Sequencing Informatics by Software Function
Sequencing Instruments and Consumables
Sequencing Instrument and Consumable Market by Product Type
Sequencing Instruments and Consumables by Platform
Sequencing Instruments and Consumables by Instrument Class
Sequencing Service Market
Chinese Clinical Sequencing Market
Applied Sequencing Service Market

CHAPTER 7 SEQUENCING MARKET IN OTHER REGIONS

Overview
Industry Details
Driving Forces
Pre- and Post-Sequencing Products
Sequencing Sample Prep Market by Application
Sequencing Informatics by Software Function
Sequencing Instruments and Consumables
Sequencing Instrument and Consumable Market by Product Type
Sequencing Instruments and Consumables by Platform
Sequencing Instruments and Consumables by Instrument Class
Sequencing Service Market
Clinical Sequencing Service Market
Applied Sequencing Services Market

CHAPTER 8 INDUSTRY STRUCTURE AND MARKET STRATEGIES

Industry Structure
BGI Model
Main Characteristics
Disadvantages
Strategies
Market Channels
Instruments and Consumables
Sequencing Services
Bioinformatics

CHAPTER 9 COMPANY PROFILES

Guangdong
ANCHORDX
BURNING ROCK
DAAN GENE
DARUI BIOTECHNOLOGY CO. LTD.
EZLIFE
FOREVER GEN
GENE DENOVO
IGE
KINGMED DIAGNOSTICS CENTER CO. LTD.
LINKED BIOTECH
MAGIGEN
RIBOBIO
TOP GENE
Shenzhen
BGI
DIRECT GENOMICS
HAPLOX
HYK GENE TECHNOLOGY CO. LTD.
IMUNO BIOTECH CO. LTD.
MACROGEN
MICROBIOTA
TGS
YUCEBIO CO. LTD.
CAPITALGENOMICS CO. LTD.
Beijing
ALLWEGENE
ANNOROAD GENE TECHNOLOGY
BERRY GENOMICS CO. LTD.
BIOLOGICAL COMPANY DIVISION, BEIJING COMPUTING CENTER
BIOMARKER
BOHENG
CAPITALBIO TECHNOLOGY
CYGNUS
EMEI TONGDE
GENECAST
GENEDOCK
GENEKANG
GENETRON
GENNLIFE
HIKEWELL
HKGI
HONOR TECH
HUANIU BIOTECHNOLOGY
HUASHENG HENGYE
HUAYIGENOMICS
IGENETECH
IMH BIO
IPE
JABREHOO
LUCIDUS
MICROHELIX GENE
MICROREAD
MYGENOSTICS
NOVOGENE BIOINFORMATICS TECHNOLOGY CO. LTD.
ORIGENE CHINA
QUANTI HEALTH
QY NODE
READER BIOINFORMATICS
SANVALLEY
SCISOON
SINOGENOMAX
SINOMDGENE
SINOPATH
SOLOMEN BROTHERS
VISHUOS
YIKON GENOMICS CO. LTD.
Shanghai
3D MEDICINES CORPORATION
ACCURAGEN INC.
ADICON CLINICAL LABORATORIES
BASETRA SHANGHAI
BENEGENE
BIOGENIUS
BIOON
BIOREFER
BIOTECAN
BIOTECHNOLOGY SHANGHAI
BIOTREE
CLOUDHEALTH MEDICAL GROUP LTD.
FIND BIO-TECH
GEMPLE
GENERGY SHANGHAI
GMINIX
HANYU
JIAYIN
KANGCHEN BIO-TECH
LOGIC INFORMATICS CO. LTD.
MAJORBIO
NOVELBIO
OEBIOTECH
OFFO
PAIHANG
QUANMAI
REALGENE
SANGON BIOTECH
SENSICHIP
SHANGHAI BIOASIA GENE CO. LTD.
SHANGHAI PERSONAL BIOTECHNOLOGY CO. LTD.
SHANGHAI YUNYING MEDICAL TECHNOLOGY CO. LTD.
SOUTH GENE
TINYGENE
TRI-I
UNIMED DIAGNOSTIC TECHNOLOGY LTD.
WUXI APPTEC
XINPEIJING
XYBIOTECH
YINGBIO
ZI BIO TECH
Zhejiang
ADICON CLINICAL LABORATORIES, INC.
BIOSAN
DIAN DIAGNOSTICS
HANGZHOU G-BIO BIOTECH CO. LTD.
HANGZHOU HEYI GENE TECHNOLOGY CO. LTD.
HANGZHOU LIANCHUAN BIO TECHNOLOGIES CO. LTD.
HANGZHOU MITIAN GENE TECHNOLOGY CO. LTD.
HANGZHOU PTM BIOLABS CO. INC.
HANGZHOU RUICHUANG BIOTECHNOLOGY CO. LTD.
HANGZHOU SHENGTING BIOTECH CO. LTD.
NEW HORIZON HEALTH
ZHEJIANG TIANKE HI-TECHNOLOGY DEVELOPMENT CO. LTD.
Jiangsu
BASECARE
BIONOVOGENE
CYAGEN
GENESEEQ
GENESKY
GENEWIZ
SUPERBIO
SUZSHOU BIOMEDICAL RESEARCH AND DEVELOPMENT CENTERS
Hubei
ABLIFE INC.
BENAGEN
FRASERGEN
GENEOCEAN
KINDSTAR
NEXTOMICS
Other Provinces
23MOFANG
RHONIN
ZIXIN PHARMACEUTICAL INDUSTRIAL CO. LTD.

CHAPTER 10 APPENDIX: GLOSSARY

List Of Tables

LIST OF TABLES

Summary Table: Chinese Sequencing Market, by Product Type, Through 2022
Table 1: Chinese Sequencing Market, by Major Segment, Through 2022
Table 2: Chinese Sequencing Market, by Province, Through 2022
Table 3: Sequencing Companies in China, by Region, Through December 2017
Table 4: Chinese Pre- and Post-Sequencing Product Market, by Major Type, Through 2022
Table 5: Chinese Sequencing Sample Prep Market, by Application, Through 2022
Table 6: Chinese Sequencing Informatics Market, by Function, Through 2022
Table 7: Next-Generation Sequencers in China, by Region, 2017
Table 8: Chinese Sequencing Instrument and Consumable Market, by Product Type, Through 2022
Table 9: Chinese Next-Generation Sequencing Instrument Companies, 2017
Table 10: Comparison of BGISeq 500 and NextSeq 500, 2017
Table 11: Chinese Sequencing Instrument Market, by Platform, Through 2022
Table 12: Chinese Sequencing Instrument and Consumable Market, by Instrument Class, Through 2022
Table 13: Chinese Sequencing Services Market, by End Use, Through 2022
Table 14: Chinese Clinical Diagnosis Cases, by Region or Province, 2017
Table 15: Chinese Clinical Sequencing Service Market, by Indication, Through 2022
Table 16: Chinese Clinical Cancer Market, by Indication, Through 2022
Table 17: Chinese Cancer Cases, by Indication, 2016
Table 18: Chinese Cancer Cases, by Region, 2016
Table 19: Chinese Clinical Next-Generation Sequencing Cancer Test Market, by Test Purpose, Through 2022
Table 20: Chinese Clinical Cancer Market, by Test Complexity, Through 2022
Table 21: Chinese Clinical Reproductive Health Market, by Application, Through 2022
Table 22: Chinese Births, by Region, 2016
Table 23: Chinese Next-Generation Sequencing NIPT Industry, 2017
Table 24: Chinese NIPT Market, by Risk Type, Through 2022
Table 25: Chinese ART Centers, by Region, April 2017
Table 26: Chinese Reproductive Health Sequencing Market, by Test Complexity, Through 2022
Table 27: Chinese Transplant Market, by Analysis Purpose, Through 2022
Table 28: Chinese Transplant Cases, by Organ Type, 2015 and 2016
Table 29: Chinese Sequencing Market for Transplant Monitoring, by Organ Type, Through 2022
Table 30: Chinese Sequencing Service Market, by Test Complexity, Through 2022
Table 31: Chinese Clinical Sequencing Market, by Test Purpose, Through 2022
Table 32: Chinese Applied Sequencing Services Market, by Application, Through 2022
Table 33: Chinese Sequencing Services Market, by Genome Type, Through 2022
Table 34: Guangdong DNA Sequencing Market, by Major Segment, Through 2022
Table 35: Guangdong Sequencing Market, by City, Through 2022
Table 36: Guangdong Pre- and Post-Sequencing Product Market, by Major Type, Through 2022
Table 37: Guangdong Sequencing Sample Prep Market, by Application, Through 2022
Table 38: Guangdong Sequencing Informatics Market, by Software Function, Through 2022
Table 39: Guangdong Sequencing Instrument and Consumable Market, by Product Type, Through 2022
Table 40: Guangdong Sequencing Instrument Market, by Platform, Through 2022
Table 41: Guangdong Sequencing Instrument and Consumable Market, by Instrument Class, Through 2022
Table 42: Guangdong Sequencing Service Market, by End Use, Through 2022
Table 43: Guangdong Clinical Sequencing Service Market, by Indication, Through 2022
Table 44: Guangdong Clinical Cancer Sequencing Market, by Indication, Through 2022
Table 45: Guangdong Cancer Liquid Biopsy Sequencing Companies, by 2017
Table 46: Guangdong Reproductive Health Market, by Indication, Through 2022
Table 47: Guangdong NIPT Sequencing Service Market, by Risk Type, Through 2022
Table 48: Guangdong Applied Sequencing Service Market, by Application, Through 2022
Table 49: Beijing Sequencing Market, by Major Segment, Through 2022
Table 50: Beijing Pre- and Post-Sequencing Product Market, by Major Type, Through 2022
Table 51: Beijing Sequencing Sample Prep Market, by Application, Through 2022
Table 52: Beijing Sequencing Informatics Market, by Software Function, Through 2022
Table 53: Beijing Sequencing Instrument and Consumable Market, by Product Type, Through 2022
Table 54: Beijing Sequencing Instrument Market, by Platform, Through 2022
Table 55: Beijing Sequencing Instrument and Consumable Market, by Instrument Class, Through 2022
Table 56: Beijing Sequencing Service Market, by End Use, Through 2022
Table 57: Beijing Clinical Sequencing Service Market, by Indication, Through 2022
Table 58: Beijing Clinical Cancer Sequencing Market, by Indication, Through 2022
Table 59: Beijing Cancer Liquid Biopsy Sequencing Companies, 2017
Table 60: Beijing Reproductive Health Market, by Application, Through 2022
Table 61: Beijing NIPT Market, by Risk Type, Through 2022
Table 62: Beijing Applied Sequencing Service Market, by Application, Through 2022
Table 63: Shanghai Sequencing Market, by Major Segment, Through 2022
Table 64: Shanghai Pre- and Post-Sequencing Product Market, by Major Type, Through 2022
Table 65: Shanghai Sequencing Sample Prep Market, by Application, Through 2022
Table 66: Shanghai Sequencing Informatics Market, by Software Function, Through 2022
Table 67: Shanghai Sequencing Instrument and Consumable Market, by Product Type, Through 2022
Table 68: Shanghai Sequencing Instrument Market, By Platform, Through 2022
Table 69: Shanghai Sequencing Instrument and Consumable Market, by Instrument Class, Through 2022
Table 70: Shanghai Sequencing Service Market, by End Use, Through 2022
Table 71: Shanghai Clinical Sequencing Service Market, by Indication, Through 2022
Table 72: Shanghai Clinical Cancer Sequencing Market, by Indication, Through 2022
Table 73: Shanghai Cancer Liquid Biopsy Sequencing Companies, 2017
Table 74: Shanghai Reproductive Health Market, by Application, Through 2022
Table 75: Shanghai NIPT Market, by Risk Type, Through 2022
Table 76: Shanghai Applied Sequencing Service Market, by Application, Through 2022
Table 77: Sequencing Market in Other Chinese Regions, by Major Segment, Through 2022
Table 78: Pre- and Post-Sequencing Product Market in Other Regions, by Major Type, Through 2022
Table 79: Sequencing Sample Prep Market in Other Regions, by Application, Through 2022
Table 80: Other Regions Sequencing Informatics Market, by Software Function, Through 2022
Table 81: Other Regions Sequencing Instrument and Consumable Market, by Product Type, Through 2022
Table 82: Other Regions Sequencing Instrument Market, by Platform, Through 2022
Table 83: Other Regions Sequencing Instrument and Consumable Market, by Instrument Class, Through 2022
Table 84: Other Regions Sequencing Service Market, by End Use, Through 2022
Table 85: Clinical Sequencing Service Market in Other Regions, by Indication, Through 2022
Table 86: Other Regions Clinical Cancer Market, by Indication, Through 2022
Table 87: Cancer Liquid Biopsy Sequencing Companies in Other Regions, 2017
Table 88: Reproductive Health Market in Other Regions, by Application, Through 2022
Table 89: Other Regions NIPT Market, by Risk Type, Through 2022
Table 90: Other Regions Applied Sequencing Services Market, by Application, Through 2022

List Of Figures

LIST OF FIGURES

Summary Figure: Chinese Sequencing Market, by Product Type, 2016-2022
Figure 1: Chinese Sequencing Market, by Major Segment, 2016-2022
Figure 2: Chinese Sequencing Market, by Province, 2016-2022
Figure 3: Leading Chinese Provinces for Sequencing Business, 2017
Figure 4: Guangdong DNA Sequencing Market, by Major Segment, 2016-2022
Figure 5: Beijing Sequencing Market, by Major Segment, 2016-2022
Figure 6: Shanghai Sequencing Market, by Major Segment, 2016-2022
Figure 7: Sequencing Market in Other Chinese Regions, by Major Segment, 2016-2022

COMPANIES MENTIONED

23MOFANG
3D MEDICINES CORPORATION
ABLIFE INC.
ACCURAGEN INC.
ADICON CLINICAL LABORATORIES
ADICON CLINICAL LABORATORIES, INC.
ALLWEGENE
AnchorDx
ANNOROAD GENE TECHNOLOGY
BASECARE
BASETRA SHANGHAI
BENAGEN
BENEGENE
BERRY GENOMICS CO. LTD.
BGI
BIOGENIUS
BIOLOGICAL COMPANY DIVISION, BEIJING COMPUTING CENTER
BIOMARKER
BIONOVOGENE
BIOON
BIOREFER
BIOSAN
BIOTECAN
BIOTECHNOLOGY SHANGHAI
BIOTREE
BOHENG
Burning Rock
CAPITALBIO TECHNOLOGY
CAPITALGENOMICS CO. LTD.
CLOUDHEALTH MEDICAL GROUP LTD.
CYAGEN
CYGNUS
Daan Gene
DARUI BIOTECHNOLOGY CO. LTD.
DIAN DIAGNOSTICS
Direct Genomics
EMEI TONGDE
EZlife
FIND BIO-TECH
Forever Gen
FRASERGEN
GEMPLE
Gene Denovo
GENECAST
GENEDOCK
GENEKANG
GENEOCEAN
GENERGY SHANGHAI
GENESEEQ
GENESKY
GENETRON
GENEWIZ
GENNLIFE
GMINIX
HANGZHOU G-BIO BIOTECH CO. LTD.
HANGZHOU HEYI GENE TECHNOLOGY CO. LTD.
HANGZHOU LIANCHUAN BIO TECHNOLOGIES CO. LTD.
HANGZHOU MITIAN GENE TECHNOLOGY CO. LTD.
HANGZHOU PTM BIOLABS CO. INC.
HANGZHOU RUICHUANG BIOTECHNOLOGY CO. LTD.
HANGZHOU SHENGTING BIOTECH CO. LTD.
HANYU
Haplox
HIKEWELL
HKGI
HONOR TECH
HUANIU BIOTECHNOLOGY
HUASHENG HENGYE
HUAYIGENOMICS
HYK Gene Technology Co. Ltd.
IGE
IGENETECH
IMH BIO
IMUNO BIOTECH CO. LTD.
IPE
JABREHOO
JIAYIN
KANGCHEN BIO-TECH
KINDSTAR
KINGMED DIAGNOSTICS CENTER CO. LTD.
LINKED BIOTECH
LOGIC INFORMATICS CO. LTD.
LUCIDUS
Macrogen
MAGIGEN
MAJORBIO
Microbiota
MICROHELIX GENE
MICROREAD
MYGENOSTICS
NEW HORIZON HEALTH
NEXTOMICS
NOVELBIO
NOVOGENE BIOINFORMATICS TECHNOLOGY CO. LTD.
OEBIOTECH
OFFO
ORIGENE CHINA
PAIHANG
QUANMAI
QUANTI HEALTH
QY NODE
READER BIOINFORMATICS
REALGENE
RHONIN
RiboBio
SANGON BIOTECH
SANVALLEY
SCISOON
SENSICHIP
SHANGHAI BIOASIA GENE CO. LTD.
SHANGHAI PERSONAL BIOTECHNOLOGY CO. LTD.
SHANGHAI YUNYING MEDICAL TECHNOLOGY CO. LTD.
SINOGENOMAX
SINOMDGENE
SINOPATH
SOLOMEN BROTHERS
SOUTH GENE
SUPERBIO
SUZSHOU BIOMEDICAL RESEARCH AND DEVELOPMENT CENTERS
TGS
TINYGENE
Top Gene
TRI-I
UNIMED DIAGNOSTIC TECHNOLOGY LTD.
VISHUOS
WUXI APPTEC
XINPEIJING
XYBIOTECH
YIKON GENOMICS CO. LTD.
YINGBIO
YuceBio Co. Ltd.
ZHEJIANG TIANKE HI-TECHNOLOGY DEVELOPMENT CO. LTD.
ZI BIO TECH
ZIXIN PHARMACEUTICAL INDUSTRIAL CO. LTD.