Tumor Markers, and Strategic Profiles of Leading Reagent and Instrument Suppliers
This 286-page report presents comprehensive marketing and technological assessment, as well as medical rationale and diagnostic prospects for major categories of both circulating and cellular tests, such as Biochemical Markers, Oncogenes, Growth Factors, Hormones, Colony Stimulating Factors, Lymphokines, Immunohistochemical Stains and others.
1. INTRODUCTION
2. TUMOR MARKER CLASSIFICATION
3. ACTH
4. ALPHAFETOPROTEIN (AFP)
5. BETA2 MICROGLOBULIN
6. CA 153/27.29
7. CA 199
8. CA125
9. CALCITONIN
10. CARCINOEMBRIONIC ANTIGEN (CEA)
11. ESTROGEN AND PROGESTERONE RECEPTORS
12. FERRITIN
13. GASTRIN
14. HUMAN CHORIONIC GONADOTROPIN (HCG)
15. INSULIN
16. NSE
17. OCCULT BLOOD
18. PAP SMEAR/HPV
19. PROSTATIC ACID PHOSPHATASE (PAP)
20. PROSTATESPECIFIC ANTIGEN (PSA)
21. SQUAMOUS CELL CARCINOMA ANTIGEN (SCC)
22. T AND B LYMPHOCYTES
23. TDT
24. THYROGLOBULIN
25. TISSUE POLYPEPTIDE ANTIGEN (TPA)
26. BIOCHEMICAL TUMOR MARKERS
ADA
BProtein
PNP
5'Nucleotidase
27. ONCOGENES
Abl/ablbcr
AIB1
BCL2
BRCA1
CD44
Cfos
Cmyb
Cmyc
CYP17
ErbB
HPC1
Nmyc
P40
P51
P53
PIK3CA
PTI1
Ras
Reg
Sis
Src
28. POLYPEPTIDE GROWTH FACTORS
Basic Fibroblast Growth Factor
BetaTGF
Cachectin (TNT)
Calmodulin
ECFR
Nerve Growth Factor (NGF)
Epidermal Growth Factor (EGF)
Ornithine Decarboxylase
Transferrin
Transforming Growth FactorAlpha
29. ECTOPIC HORMONES
30. COLONY STIMULATING FACTORS
31. LYMPHOKINES
AlphaInterferon
B Cell Growth Factors
B Cell Growth Factor (BCGF)
GammaInterferon
Interleukin1 (IL1)
Macrophage Activating Factor
32. IMMUNOHISTOCHEMICAL STAINS
33. EMERGING TUMOR MARKERS
NAcetylglucosamine
Actin
AlphaActin
Antineuronal Antibodies
7B2
B72.3
Bax
BCDF9
BLCA4
Blood Group Antigens A,B,H
CA
CA 724/TAG72
CA
CA242
CA549
CAM
CAR3
CathepsinD
Chromogranin A and B
Cluster 1 Antigen
Cluster5/5A Antigen
CTA
CU18
DR70
DUPAN2
Endometrial Bleeding Associated Factor
Endostatin
Epithelial Membrane Antigen
Feulgen Hydrolysis
Fibronectin
FSH
(1>3)Lfucosyltransferase
GastrinReleasing Peptide (GRP)
GDCFP15
Glucagon
Glycoamines
H23
Her2
Human Carcinoma Antigen
HPA
HSP27
Intermediate Filaments
Cytokeratins/CK18/Cyfra 211
Desmin
Gliofibrillary Acid Protein
Neurofilaments
Vimentin
KA
Kinases
KP16D3
LAI
Leukocyte Common Antigen
Lewis Antigens
Lysophosphatidic Acid (LPA)
Ma 695/Ma
MABDF3
MAG
ME1
Minactivin
MN/CA9
MSA
Mucin Cancer Antigen (MCA)
Multiple Tumor Suppressor
Myosin
NEA130
NMP22
OA519
Opiod Peptides
Pglycoprotein
Pancreatic Oncofetal Antigen (POA)
Placental Lactogen
PR92
Proliferative Index, Ki67
Px
RB Inactivation/Deletion
Ret
SCCL
Selectin
Sialic Acid
Sialyl SSEA1/SLX
SN10
Somatostatin
TA90
TABA
Tachykinin
TAG
TPS
Troponin
Tubulin
VCAM
VEGF
Villen
COMPETITIVE PROFILES
Abbott
AdnaGen/Alere
Applied Gene Technologies
Arca Biopharma
Beckman Coulter/Danaher
Becton Dickinson
Biomedical Diagnostics
bioMerieux
BioRad
CellSearch
Cepheid
Correlogic Systems/Vermillion
Decode Genetics
Diadexus
Diagnocure
Diasorin
Eiken Chemical
Elitech Group
Enterix
Enzo Biochem
Epigenomics
Exact Sciences
Fujirebio
GenProbe
Guided Therapeutics
Hologic/GenProbe
Kreatech/Leica
Kyowa Medex
Mackay Life Sciences
Myriad Genetics
OncoLab
OrthoClinical Diagnostics
Panacea Pharmaceuticals
Polartechnics
Polymedco
PreMD
Qiagen
Radient Pharmaceuticals
Roche
Scienion
Sequenom
Siemens Healthcare
Takara Bio
Targeted Diagnostics & Therapeutics
Thermo Fisher
Tosoh
Veridex
Wako Pure Chemicals
Wallac/PE
Zila/Alere
Appendixes
Appendix I: Major Universities and Research
Centers Developing Cancer Diagnostic
Technology and Applications
2. TUMOR MARKER CLASSIFICATION
3. ACTH
4. ALPHAFETOPROTEIN (AFP)
5. BETA2 MICROGLOBULIN
6. CA 153/27.29
7. CA 199
8. CA125
9. CALCITONIN
10. CARCINOEMBRIONIC ANTIGEN (CEA)
11. ESTROGEN AND PROGESTERONE RECEPTORS
12. FERRITIN
13. GASTRIN
14. HUMAN CHORIONIC GONADOTROPIN (HCG)
15. INSULIN
16. NSE
17. OCCULT BLOOD
18. PAP SMEAR/HPV
19. PROSTATIC ACID PHOSPHATASE (PAP)
20. PROSTATESPECIFIC ANTIGEN (PSA)
21. SQUAMOUS CELL CARCINOMA ANTIGEN (SCC)
22. T AND B LYMPHOCYTES
23. TDT
24. THYROGLOBULIN
25. TISSUE POLYPEPTIDE ANTIGEN (TPA)
26. BIOCHEMICAL TUMOR MARKERS
ADA
BProtein
PNP
5'Nucleotidase
27. ONCOGENES
Abl/ablbcr
AIB1
BCL2
BRCA1
CD44
Cfos
Cmyb
Cmyc
CYP17
ErbB
HPC1
Nmyc
P40
P51
P53
PIK3CA
PTI1
Ras
Reg
Sis
Src
28. POLYPEPTIDE GROWTH FACTORS
Basic Fibroblast Growth Factor
BetaTGF
Cachectin (TNT)
Calmodulin
ECFR
Nerve Growth Factor (NGF)
Epidermal Growth Factor (EGF)
Ornithine Decarboxylase
Transferrin
Transforming Growth FactorAlpha
29. ECTOPIC HORMONES
30. COLONY STIMULATING FACTORS
31. LYMPHOKINES
AlphaInterferon
B Cell Growth Factors
B Cell Growth Factor (BCGF)
GammaInterferon
Interleukin1 (IL1)
Macrophage Activating Factor
32. IMMUNOHISTOCHEMICAL STAINS
33. EMERGING TUMOR MARKERS
NAcetylglucosamine
Actin
AlphaActin
Antineuronal Antibodies
7B2
B72.3
Bax
BCDF9
BLCA4
Blood Group Antigens A,B,H
CA
CA 724/TAG72
CA
CA242
CA549
CAM
CAR3
CathepsinD
Chromogranin A and B
Cluster 1 Antigen
Cluster5/5A Antigen
CTA
CU18
DR70
DUPAN2
Endometrial Bleeding Associated Factor
Endostatin
Epithelial Membrane Antigen
Feulgen Hydrolysis
Fibronectin
FSH
(1>3)Lfucosyltransferase
GastrinReleasing Peptide (GRP)
GDCFP15
Glucagon
Glycoamines
H23
Her2
Human Carcinoma Antigen
HPA
HSP27
Intermediate Filaments
Cytokeratins/CK18/Cyfra 211
Desmin
Gliofibrillary Acid Protein
Neurofilaments
Vimentin
KA
Kinases
KP16D3
LAI
Leukocyte Common Antigen
Lewis Antigens
Lysophosphatidic Acid (LPA)
Ma 695/Ma
MABDF3
MAG
ME1
Minactivin
MN/CA9
MSA
Mucin Cancer Antigen (MCA)
Multiple Tumor Suppressor
Myosin
NEA130
NMP22
OA519
Opiod Peptides
Pglycoprotein
Pancreatic Oncofetal Antigen (POA)
Placental Lactogen
PR92
Proliferative Index, Ki67
Px
RB Inactivation/Deletion
Ret
SCCL
Selectin
Sialic Acid
Sialyl SSEA1/SLX
SN10
Somatostatin
TA90
TABA
Tachykinin
TAG
TPS
Troponin
Tubulin
VCAM
VEGF
Villen
COMPETITIVE PROFILES
Abbott
AdnaGen/Alere
Applied Gene Technologies
Arca Biopharma
Beckman Coulter/Danaher
Becton Dickinson
Biomedical Diagnostics
bioMerieux
BioRad
CellSearch
Cepheid
Correlogic Systems/Vermillion
Decode Genetics
Diadexus
Diagnocure
Diasorin
Eiken Chemical
Elitech Group
Enterix
Enzo Biochem
Epigenomics
Exact Sciences
Fujirebio
GenProbe
Guided Therapeutics
Hologic/GenProbe
Kreatech/Leica
Kyowa Medex
Mackay Life Sciences
Myriad Genetics
OncoLab
OrthoClinical Diagnostics
Panacea Pharmaceuticals
Polartechnics
Polymedco
PreMD
Qiagen
Radient Pharmaceuticals
Roche
Scienion
Sequenom
Siemens Healthcare
Takara Bio
Targeted Diagnostics & Therapeutics
Thermo Fisher
Tosoh
Veridex
Wako Pure Chemicals
Wallac/PE
Zila/Alere
Appendixes
Appendix I: Major Universities and Research
Centers Developing Cancer Diagnostic
Technology and Applications
LIST OF TABLES
Tumor Marker Classification
Major Companies Developing or Marketing ACTH Tests
Major Companies Developing or Marketing AFP Tests
Major Companies Developing or Marketing Beta2 Microglobulin Tests
Major Companies Developing or Marketing CA 153/27.29 Tests
Major Companies Developing or Marketing CA 199 Tests
Major Companies Developing or Marketing CA 125 Tests
Major Companies Developing or Marketing Calcitonin Tests
Major Companies Developing or Marketing CEA Tests
Major Companies Developing or Marketing Estrogen Receptor Tests
Major Companies Developing or Marketing Progesterone Receptor Tests
Major Companies Developing or Marketing Ferritin Tests
Major Companies Developing or Marketing Gastrin Tests
Major Companies Developing or Marketing HCG Tests
Major Companies Developing or Marketing Insulin Tests
Major Companies Developing or Marketing NSE Tests
Major Companies Developing or Marketing Occult Blood Tests
Major Companies Developing or Marketing PAP Smear/HPV Tests
Major Companies Developing or Marketing PAP Tests
Major Companies Developing or Marketing PSA Tests
Major Companies Developing or Marketing Lymphocyte Subclassification Tests
Biochemical Markers Potential Applications
In Cancer Diagnosis
Oncogenes Potential Applications
In Cancer Diagnosis
Major Companies Developing or Marketing Oncogene Tests
Growth Factors Potential Applications
In Cancer Diagnosis
Colony Stimulating Factors Potential
Applications in Cancer Diagnosis
Lymphokines Potential Applications
In Cancer Diagnosis
Immunohistochemical Stains Potential
Applications in Cancer Diagnosis
Tumor Marker Classification
Major Companies Developing or Marketing ACTH Tests
Major Companies Developing or Marketing AFP Tests
Major Companies Developing or Marketing Beta2 Microglobulin Tests
Major Companies Developing or Marketing CA 153/27.29 Tests
Major Companies Developing or Marketing CA 199 Tests
Major Companies Developing or Marketing CA 125 Tests
Major Companies Developing or Marketing Calcitonin Tests
Major Companies Developing or Marketing CEA Tests
Major Companies Developing or Marketing Estrogen Receptor Tests
Major Companies Developing or Marketing Progesterone Receptor Tests
Major Companies Developing or Marketing Ferritin Tests
Major Companies Developing or Marketing Gastrin Tests
Major Companies Developing or Marketing HCG Tests
Major Companies Developing or Marketing Insulin Tests
Major Companies Developing or Marketing NSE Tests
Major Companies Developing or Marketing Occult Blood Tests
Major Companies Developing or Marketing PAP Smear/HPV Tests
Major Companies Developing or Marketing PAP Tests
Major Companies Developing or Marketing PSA Tests
Major Companies Developing or Marketing Lymphocyte Subclassification Tests
Biochemical Markers Potential Applications
In Cancer Diagnosis
Oncogenes Potential Applications
In Cancer Diagnosis
Major Companies Developing or Marketing Oncogene Tests
Growth Factors Potential Applications
In Cancer Diagnosis
Colony Stimulating Factors Potential
Applications in Cancer Diagnosis
Lymphokines Potential Applications
In Cancer Diagnosis
Immunohistochemical Stains Potential
Applications in Cancer Diagnosis