2017 Emerging Nucleic Acid Testing (NAT) Assays, and Strategic Profiles of Leading Reagent and Instrument Suppliers

January 2017 | 549 pages | ID: 2B67A197162EN
Venture Planning Group

Abstracts

This 549-page report presents an overview of the clinical significance and market needs for major current and emerging NAT assays, as well as extensive listings of companies developing and marketing innovative technologies and products. This report also presents strategic assessments of current and emerging suppliers of nucleic acid testing products, including their sales, product portfolios, marketing tactics, technological know-how, new products in R&D, collaborative arrangements and business strategies. Contains 549 pages and 22 tables

Contents

MICROBIOLOGY/INFECTIOUS DISEASES

a. Overview
b. Major Infectious Diseases
  AIDS
  Structure and Composition
  Classification
  AIDS Origins
  Animal Lentivirus Systems
  Virus Receptors
  HIV Infections in Humans
    Pathogenesis and Pathology
  CD4T Lymphocytes and Memory Cells
  Monocytes and Macrophages
  Lymphoid Organs
  Neural Cells
  Viral Coinfections
    Clinical Findings
  Plasma Viral Load
  Pediatric AIDS
    Neurologic Disease
    Opportunistic Infections
    Cancer
  Immunity
    Virus Isolation
    Serology
    Viral Nucleic Acid/Antigen Detection
  Epidemiology
    Worldwide Spread of AIDS
    United States
    Routes of Transmission
  DNA Probes
    Overview
    Quantitative PCR
    In Situ PCR
    Needed Improvements
  Viral Load/Drug Resistance Testing
  Genotype and Phenotype Testing
  Blood Banking Considerations
    Adenovirus
  Background
  Diagnostic Tests
  Vaccines and Drugs
  Adeno-Associated Viruses (AAV)
    Background
  Diagnostic Tests
  Vaccines and Drugs
    Babesiosis
  Background
    BEA and Other Bartonella Diseases
  Background
  Diagnostic Tests
  Vaccines and Drugs
    Chagas Disease
  Background
    Campylobacter
  Background
  Diagnostic Tests
    Culture Identification
  Vaccines and Drugs
    Chlamydia
  Background
    Chlamydia psittaci
    Chlmaydia pneumoniae
    Chlamydia trachomatis
  Diagnostic Tests
  Vaccines and Drugs
    Creutzfeldt-Jakob’s Disease
  Background
  Blood Transmission
  Diagnostic Tests
  Major Commercial and Academic Players
    Bayer
    Disease Sciences/Bio Tec Global
    Imperial College School of Medicine
    Ortho-Clinical Diagnostics
    Pall
    ProMetic Life Sciences
    Proteome Sciences/Idexx
    Q-One Biotech
    Serono
    U.S. Agricultural Research Service
  Drugs
  Vaccines
    Cytomegalovirus
  Background
    Chorioretinitis
    Gastrointestinal
    Central Nervous System Disease
  Diagnostic Tests
  Vaccines and Drugs
    Ebola Virus
  Background
    Epidemiology
    Clinical Syndromes
  Diagnostic Tests
  Vaccines and Drugs
    EchoVirus
  Background
    Acute Aseptic Meningitisis
    Encephalitis
    Exanthems
    Respiratory Disease
    Myopericarditis
    Neonatal Infections
  Diagnostic Tests
  Vaccines and Drugs
    Encephalitis
  Background
  Diagnostic Tests
  Vaccines and Drugs
    Enteroviruses
  Background
  Diagnostic Tests
    Viral Isolation and Identification
    Antibody Tests
  Vaccines and Drugs
    Epstein-Barr Virus
  Background
  Diagnostic Tests
  Vaccines and Drugs
    Gonorrhea
  Background
  Diagnostic Tests
  Vaccines and Drugs
    Hepatitis
  Hepatitis A
  Hepatitis B
    Structure and Composition
    Replication
  Hepatitis C
  Hepatitis D (Delta)
  Hepatitis E
  Hepatitis G
  Hepatitis Infections Pathology
  Clinical Findings
  Laboratory Tests
    Hepatitis A
    Hepatitis B
    Hepatitis C
    Hepatitis D
    Hepatitis E
  Virus-Host Immune Reactions
  Epidemiology
    Hepatitis A
    Hepatitis B
    Hepatitis C
  Hepatitis D (Delta)
  Vaccines and Drugs
    Herpes Simplex Virus
  Background
  Diagnostic Tests
  Vaccines and Drugs
    Legionella
  Background
  Diagnostic Tests
  Vaccines and Drugs
    Lyme Disease
  Background
    Clinical Description
    Clinical Case Definition
    Laboratory Criteria for Diagnosis
    Case Classification
  Diagnostic Tests
  Vaccines and Drugs
    Malaria
    Mycoplasma
  Background
    Ureaplasma Urealyticum & Mycoplasma Hominis
  Diagnostic Tests
  Vaccines and Drugs
    Papillomaviruses/HPV
  Background
    HPV in Cancer
    Cervical Neoplasm
  Diagnostic Tests
  Vaccines and Drugs
    Prevention
    Parvovirus B19
  Background
    Microbiology
    Epidemiology
    Clinical Syndromes
    Erythema Infectiosum (Slapped Cheek)
    Adult Polyarthropathy
    Transient Aplastic Crisis
    Transient Pancytopenia
    Red Cell Aplasia in Immunocompromised
    Perinatal Infections
  Diagnostic Test
  Vaccines and Drugs
    Pneumonia
  Background
  Diagnostic Tests
  Vaccines and Drugs
    Polyomaviruses
  Background
  Diagnostic Tests
  Vaccines and Drugs
      Salmonellosis
  Background
  Diagnostic Tests
  Vaccines and Drugs
      Shigellosis
  Background
  Diagnostic Tests
  Vaccines and Drugs
      Streptococci
  Background
  Diagnostic Tests
  Vaccines and Drugs
    Group A Streptococci
    Group B Streptococci
      Toxoplasmosis
  Background
  Diagnostic Tests
  Vaccines and Drugs
      Tuberculosis
  Background
  Diagnostic Tests
    Microscopic Characteristics
    Cultural Characteristics
    Skin Tests
    MDRTB
  Vaccines and Drugs
    West Nile Virus
  Background
    Clinical Syndromes
  Diagnostic Tests
  Vaccines and Drugs
    Yersinia
  Background
  Diagnostic Tests
  Vaccines and Drugs
    Antibiotic Susceptibility

CANCER TESTING

a. Overview
b. Major Cancer Types
  Prostate
  Lung
  Colon and Rectum
  Breast
  Skin
  Uterine
  Leukemia
  Oral
c. Oncogenes
  Abl/abl-bcr
  AIB1
  BCL-2
  BRCA1
  CD44
  C-fos
  C-myb
  C-myc
  CYP17
  Erb-B
  HPC1
  N-myc
  P40
  P51
  P53
  PIK3CA
  PTI-1
  Ras
  Reg
  Sis
  Src

GENETIC DISEASES

a. Overview
b. Nucleic Acid Amplification
c. Chromosome Imaging
d. Genomics Technologies
e. Proteomics Technologies
f. Current Pharmacogenomic Tests
g. Future Pharmacogenomic Testing
h. Major Diseases
  Achondroplasia
  Autosomal Dominant Polycystic Kidney Disease
  Cancer
  Cosmetogenomics
  Cystic Fibrosis
  Down's Syndrome
  Duchenne and Becker Muscular Dystrophy
  Factor V (Leiden)
  Factor IX Deficiency
  Fragile X Syndrome
  Heart Disease
  Hemochomatosis
  Hemophilia
  Huntington's Disease
  Maternal-Fetal Incompatibility
  Multiple Endocrine Neoplasia
  Phenylketonuria (PKU)
  Polycystic Kidney Disease (PKD)
  Prenatal Screening
  Retinitis Pigmentosa
  Retinoblastoma
  Sickle Cell Anemia
  Spinal Muscular Atrophy
  Vitamin B12 Metabolism
i. Social Issues and Concerns

FORENSIC TESTING

a. Overview
b. Multilocus and Single Locus Probes
  Multilocus Probes
  Single Locus Probes
  PCR and RFLP
c. The FBI
d. DNA Profile Data Banks
  U.S.A.
  U.K.
e. Judicial Implementation
f. Major Crime Categories
g. Factors Contributing to the DNA Probe Market Expansion
  Technology Availability
  Use of Hair as Evidence
h. Wildlife Forensics

PATERNITY TESTING/HLA TYPING

OTHER APPLICATIONS

a. Disease Susceptibility Testing
b. Cardiovascular Diseases
c. Diabetes
d. Alzheimer's Disease
e. Periodontal Disease
f. Plasma Purification
g. Organ Transplantation
h. Water Contamination
i. Other

COMPETITIVE PROFILES

Abbott
Affymetrix
Agilent Technologies
Applied Gene Technologies
Arca Biopharma
Beckman Coulter/Danaher
Becton Dickinson
Biokit
BioMerieux
Bio-Rad
Biotest
Cepheid
CellMark Forensics/LabCorp
Decode Genetics
Diadexus
Elitech Group
Eiken
Enzo
Exact Sciences
Fujirebio
Grifols
Hologic/Gen-Probe
Illumina
Kreatech/Leica
Li-Cor Biosciences
Monogram Biosciences
Myriad Genetics
Ortho-Clinical Diagnostics
Perkin Elmer/Caliper
Proteome Sciences
Qiagen
Roche
Scienion
Sequenom
Shimadzu
Siemens
Sierra Molecular
Takara Bio
Tecan Group
Thermo Fisher

List Of Tables

LIST OF TABLES

Major Companies Developing or Marketing AIDS Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Adenovirus Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Campylobacter Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Chlamydia Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing CMV Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing EBV Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Gonorrhea Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Hepatitis Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Herpes Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Legionella Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Lyme Disease Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Mycoplasma Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Papilloma Virus Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Pneumonia Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Salmonella Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Shigella Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Streptococci Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Toxoplasmosis Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Tuberculosis Molecular Diagnostic And Other Direct Identification Tests Oncogenes Potential Application in Cancer Diagnosis
Major Companies Developing or Marketing Cancer Molecular Diagnostic Tests
Major Companies Developing or Marketing Molecular Diagnostic Test For Genetic Diseases