2015 Strategies in the US Tumor Marker Testing Market

May 2015 | 620 pages | ID: 249C1D2AC1AEN
Venture Planning Group

Abstracts

Highlights

• Comprehensive 620-page analysis of the US tumor marker testing market.
• Major issues pertaining to the US laboratory practice, as well as key economic, regulatory, demographic, social and technological trends with significant market impact during the next five years.
• Mortality statistics and scientific views on the etiology of major types of cancer, e.g., lung, colorectal, breast, prostatic, pancreatic, leukemia, lymphoma, gastrointestinal, bladder, liver, ovarian, testicular, oral, skin and others.
• Five-year test volume and sales forecasts over for 40 tumor marker performed in US hospitals, commercial laboratories and physician offices.
• Placements and installed base of automated and semi-automated analyzers used for tumor marker testing.
• Current instrumentation technologies and feature comparison of leading analyzers.
• Sales and market shares of leading suppliers.
• Emerging diagnostic technologies and their potential market applications.
• Product development opportunities.
• Profiles of current and emerging suppliers, including their sales, market shares, product portfolios, marketing tactics, technological know-how, new products in R&D, collaborative arrangements and business strategies.
• Business opportunities and strategic recommendations for suppliers.

Contains 620 pages and 103 tables

Contents

I. INTRODUCTION

II. WORLDWIDE MARKET AND TECHNOLOGY OVERVIEW

A. Cancer Statistics and Etiology
  1. Breast Cancer
  2. Lung Cancer
  3. Colon and Rectum Cancer
  4. Prostate Cancer
  5. Stomach Cancer
  6. Leukemia
  7. Lymphoma
  8. Oral Cancer
  9. Skin Cancer
  10. Uterine Cancer
  11. Ovarian Cancer
  12. Bladder Cancer
B. Major Current And Emerging Cancer Diagnostic Tests
  1. INTRODUCTION
  2. Tumor Marker Classification
  3. ACTH
  4. Alpha-Fetoprotein (AFP)
  5. Beta-2 Microglobulin
  6. CA15-3/27.29
  7. CA19-9
  8. CA-125
  9. Calcitonin
  10. Carcinoembrionic Antigen (CEA)
  11. Estrogen and Progesterone Receptors
  12. Ferritin
  13. Gastrin
  14. Human Chorionic Gonadotropin (HCG)
  15. Insulin
  16. NSE
  17. Occult Blood
  18. PAP Smear/HPV
  19. Prostatic Acid Phosphatase (PAP)
  20. Prostate-Specific Antigen (PSA)
  21. Squamous Cell Carcinoma Antigen (SCC)
  22. T and B Lymphocytes
  23. TdT
  24. Thyroglobulin
  25. Tissue Polypeptide Antigen (TPA)
  26. Biochemical Tumor Markers
    ADA
    B-Protein
    PNP
    5'-Nucleotidase
  27. Oncogenes
    Abl/abl-bcr
    AIB1
    BCL-2
    BRCA1
    CD44
    C-fos
    C-myb
    C-myc
    CYP-17
    Erb-B
    HPC1
    N-myc
    P40
    P51
    P53
    PIK3CA
    PTI-1
    Ras
    Reg
    Sis
    Src
  28. Polypeptide Growth Factors
    Basic Fibroblast Growth Factor
    Beta-TGF
    Cachectin (TNT)
    Calmodulin
    ECFR
    Nerve Growth Factor (NGF)
    Epidermal Growth Factor (EGF)
    Ornithine Decarboxylase
    Transferrin
    Transforming Growth Factor-Alpha
  29. Ectopic Hormones
  30. Colony Stimulating Factors
  31. Lymphokines
    Alpha-Interferon
    B Cell Growth Factors
    B Cell Growth Factor (BCGF)
    Gamma-Interferon
    Interleukin-1 (IL-1)
    Macrophage Activating Factor
  32. Immunohistochemical Stains
  33. Emerging Tumor Markers
    N-Acetylglucosamine
    Actin
    Alpha-Actin
    Antineuronal Antibodies
    7B2
    B72.3
    Bax
    BCD-F9
    BLCA-4
    Blood Group Antigens A,B,H
    CA50
    CA72-4/TAG-72
    CA195
    CA-242
    CA-549
    CAM26
    CAR-3
    Cathepsin-D
    Chromogranin A and B
    Cluster 1 Antigen
    Cluster-5/5A Antigen
    CTA
    CU18
    DR-70
    DU-PAN-2
    Endometrial Bleeding Associated Factor
    Endostatin
    Epithelial Membrane Antigen
    Feulgen Hydrolysis
    Fibronectin
    FSH
    (1->3)-L-fucosyltransferase
    Gastrin-Releasing Peptide (GRP)
    GDCFP-15
    Glucagon
    Glycoamines
    H23
    Her-2
    Human Carcinoma Antigen
    HPA
    HSP27
    Intermediate Filaments
    Cytokeratins/CK18/Cyfra21-1
    Desmin
    Gliofibrillary Acid Protein
    Neurofilaments
    Vimentin
    KA93
    Kinases
    KP16D3
    LAI
    Leukocyte Common Antigen
    Lewis Antigens
    Lysophosphatidic Acid (LPA)
    Ma695/Ma552
    MABDF3
    MAG
    ME1
    Minactivin
    MN/CA9
    MSA
    Mucin Cancer Antigen (MCA)
    Multiple Tumor Suppressor
    Myosin
    NEA-130
    NMP22
    OA-519
    Opiod Peptides
    P-glycoprotein
    Pancreatic Oncofetal Antigen (POA)
    Placental Lactogen
    PR92
    Proliferative Index, Ki-67
    Px
    RB Inactivation/Deletion
    Ret
    SCCL175
    Selectin
    Sialic Acid
    Sialyl SSEA-1/SLX
    SN10
    Somatostatin
    TA-90
    TABA
    Tachykinin
    TAG12
    TPS
    Troponin
    Tubulin
    VCAM
    VEGF
    Villen
C. INSTRUMENTATION Review And Market Needs
D. CURRENT AND EMERGING TECHNOLOGIES
1. Monoclonal and Polyclonal Antibodies
2. Immunoassays
  a. Technological Principle
  b. Radioimmunoassay (RIA)
  c. Enzyme Immunoassays (EIA)
    Overview
    ELISA
    Immunofiltration
    Particle-Membrane Capture Immunoassay
    Enzyme Amplification
  d. Fluorescent Immunoassays
  e. Luminescence
    Chemiluminescence
    Bioluminescence
  f. Latex Agglutination
  g. Immunoprecipitation
  h. Affinity Chromatographu
  e. Liposome Flow-Injection Immunoassay
3. Molecular Diagnostics
  a. Technology Overview
  b. Amplification Methods
4. Chromosome Analysis
  a. Chronic Myelogenous Leukemia (CML)
  b. Acute Myeloid Leukemia (AML)
  c. Acute Lymphoblastic Leukemia (ALL)
  d. Malignant Lymphomas Lymphoid Malignancies
  e. Chronic Lymphocytic Leukemia (CLL)
  f. Solid Cancers
  g. Chromosomal Translocation and Oncogenes
5. Artificial Intelligence
6. Flow Cytometry
7. Two Dimensional Gel Electrophoresis (2-DGE)
8. Biosensors
9. Competing/Complementing Technologies
  a. CT
  b. MRI
  c. NMR
  d. PET
  e. Photonics Spectroscopy
G. Personal Testing

III. U.S.A.

A. EXECUTIVE SUMMARY
B. Business Environment
C. Market Structure
D. Market Size, Growth and Major Suppliers Sales and Market Shares

1. MAJOR PRODUCT DEVELOPMENT OPPORTUNITIES

A. Reagent Kits and Test Systems/Panels
B. INSTRUMENTATION
C. Computers, Software and Automation
D. Auxiliary Products

XI. DESIGN CRITERIA FOR DECENTRALIZED TESTING PRODUCTS

XII. ALTERNATIVE MARKET PENETRATION STRATEGIES

A. Internal Development
B. Collaborative Arrangements
C. University Contracts
D. Distribution Strategies
  1. Marketing Approaches
  2. Product Complexity
  3. Customer Preference
  4. Established Suppliers
  5. Emerging Suppliers
  6. Major Types of Distributors
  7. Market Segmentation Factor

XIII. POTENTIAL MARKET ENTRY BARRIERS AND RISKS

A. Market Maturity
B. Cost Containment
C. Competition
D. Technological Edge and Limitations
E. Patent Protection
F. Regulatory Constraints
G. Decentralized Testing Market Challenges

XIV. COMPETITIVE PROFILES

Abbott
AdnaGen/Alere
Agilent Technologies
Applied Gene Technologies
Arca Pharma
Beckman Coulter/Danaher
Becton Dickinson
Biomedical Diagnostics
bioMerieux
Bio-Rad
CellSearch
Cepheid
Correlogic Systems/Vermillion
Decode Genetics
Diadexus
Diagnocure
Diasorin
Eiken Chemical
Elitech Group
Epigenomics
Enterix
Enzo Biochem
Exact Sciences
Fujirebio
Guided Therapeutics
Hologic/Gen-Probe
Kreatech/Leica
Kyowa Medex
Mackay Life Sciences
Myriad Genetics
OncoLab
Ortho-Clinical Diagnostics
Panacea Pharmaceuticals
Polartechnics
Polymedco
PreMD
Qiagen
Quest Diagnostics
Radient Pharmaceuticals
Roche
Scienion
Sequenom
Siemens Healthcare
Takara Bio
Targeted Diagnostics & Therapeutics
Thermo Fisher
Tosoh
Veridex
Wako Pure Chemicals
Wallac/PE
Zila

XV. APPENDIXES: APPENDIX I: MAJOR UNIVERSITIES AND RESEARCH CENTERS DEVELOPING CANCER DIAGNOSTIC TECHNOLOGY AND APPLICATIONS

Appendix II: Assumed Currency Exchange Rates

List Of Tables

LIST OF TABLES

Tumor Marker Classification
Major Companies Developing or Marketing ACTH Tests
Major Companies Developing or Marketing AFP Tests
Major Companies Developing or Marketing Beta-2 Microglobulin Tests
Major Companies Developing or Marketing CA15-3/27.29 Tests
Major Companies Developing or Marketing CA19-9 Tests
Major Companies Developing or Marketing CA125 Tests
Major Companies Developing or Marketing Calcitonin Tests
Major Companies Developing or Marketing CEA Tests
Major Companies Developing or Marketing Estrogen Receptor Tests
Major Companies Developing or Marketing Progesterone Receptor Tests
Major Companies Developing or Marketing Ferritin Tests
Major Companies Developing or Marketing Gastrin Tests
Major Companies Developing or Marketing HCG Tests
Major Companies Developing or Marketing Insulin Tests
Major Companies Developing or Marketing NSE Tests
Major Companies Developing or Marketing Occult Blood Tests
Major Companies Developing or Marketing PAP Smear/HPV Tests
Major Companies Developing or Marketing PAP Tests
Major Companies Developing or Marketing PSA Tests
Major Companies Developing or Marketing Lymphocyte Subclassification Tests
Biochemical Markers Potential Applications In Cancer Diagnosis
Oncogenes Potential Applications In Cancer Diagnosis
Major Companies Developing or Marketing Oncogene Tests
Growth Factors Potential Applications In Cancer Diagnosis
Colony Stimulating Factors Potential Applications in Cancer Diagnosis
Lymphokines Potential Applications In Cancer Diagnosis
Immunohistochemical Stains Potential Applications in Cancer Diagnosis
EXECUTIVE SUMMARY Table: U.S., Total Tumor Marker Test Volume and Sales Forecast By Market Segment
U.S., Estimated New Cancer Cases and Deaths
U.S., Estimated Cancer Death Rates Per 100,000 Population
U.S., Laboratories Performing Tumor Marker Tests by Market Segment
U.S., Hospital Laboratories Performing Tumor Marker Tests by Bed Size
U.S., Commercial/Private Laboratories Performing Tumor Marker Tests By Annual Test Volume
U.S., Physician Office Laboratories Performing Tumor Marker Tests By Practice Size
U.S., Total Tumor Marker Test Volume Forecast by Market Segment
U.S., All Market Segments Major Tumor Marker Test Volume Forecast
U.S., Hospital Laboratories Major Tumor Marker Test Volume Forecast by Test
U.S., Commercial/Private Laboratories Major Tumor Marker Test Volume Forecast
U.S., Physician Offices/Group Practices Major Tumor Marker Test Volume Forecast
U.S., Cancer Clinics Major Tumor Marker Test Volume Forecast by Test
U.S., Total Tumor Marker Sales Forecast by Market Segment
U.S., All Market Segment Major Tumor Marker Sales Forecast by Test
U.S., Hospital Laboratories Major Tumor Marker Sales Forecast by Test
U.S., Commercial/Private Laboratories Major Tumor Marker Sales Forecast by Test
U.S., Physician Offices/Group Practices Major Tumor Marker Sales Forecast by Test
U.S., Cancer Clinics Major Tumor Marker Sales Forecast by Test
U.S., ACTH Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., AFP Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., Beta-2 Microglobulin Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., CA15-3/27.29 Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., CA19-9 Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., CA-125 Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., Calcitonin Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., Cathepsin Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., CEA Test Volume and Diagnostics Sales by Market Segment
U.S., Chromogranin Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., Colon-specific Antigen Test Volume And Diagnostics Sales Forecast by Market Segment
U.S., Cytokeratins Test Volume And Diagnostics Sales Forecast by Market Segment
U.S., Estrogen Receptor Test Volume And Diagnostics Sales Forecast by Market Segment
U.S., Ferritin Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., Gastrin Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., HCG Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., Insulin Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., Interferons Test Volume And Diagnostics Sales Forecast by Market Segment
U.S., Interleukins Test Volume And Diagnostics Sales Forecast by Market Segment
U.S., Lymphocyte Subtyping Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., NSE Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., Nucleolar Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., Occult Blood Test Volume And Diagnostics Sales Forecast by Market Segment
U.S., Oncogenes Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., Pancreatic Oncofetal Antigen Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., PAP Smear Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., Parathyroid Hormone Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., Progesterone Receptor Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., PAP Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., PSA Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., S-100 Protein Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., Serotonin Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., Sialic Acid Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., Squamous Cell Carcinoma Antigen Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., TDT Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., Thymidine Kinase Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., Thyroglobulin Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., TPA Test Volume and Diagnostics Sales Forecast by Market Segment
U.S., Total Tumor Marker Sales By Major Supplier
U.S., ACTH Testing Market Diagnostics Sales by Major Supplier
U.S., AFP Testing Market Diagnostics Sales by Major Supplier
U.S., Beta-2 Migroblolulin Testing Market Diagnostics Sales by Major Supplier
U.S., CA15-3/27.29 Testing Market Diagnostics Sales by Major Supplier
U.S., CA19-9 Testing Market Diagnostics Sales by Major Supplier
U.S., CA125 Testing Market Diagnostics Sales by Major Supplier
U.S., CEA Testing Market Diagnostics Sales by Major Supplier
U.S., Ferritin Testing Market Diagnostics Sales by Major Supplier
U.S., HCG Testing Market Diagnostics Sales by Major Supplier
U.S., Insulin Testing Market Diagnostics Sales by Major Supplier
U.S., Parathyroid Hormone Testing Market Diagnostics Sales by Major Supplier
U.S., PAP Testing Market Diagnostics Sales by Major Supplier
U.S., Progesterone Receptor Testing Market Diagnostics Sales by Major Supplier
U.S., PSA Testing Market Diagnostics Sales by Major Supplier