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Immunohistochemistry (IHC): Global Markets to 2022

July 2018 | 184 pages | ID: I1C9BD44745EN
BCC Research

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REPORT SCOPE

The scope of this market report is widely characterized by products that include antibodies, equipment, kits and reagents. The total market revenue is restricted to the revenues obtained from the sales of the products required to perform IHC testing successfully. This report covers the different applications of immunohistochemistry in drugs and diagnostics.

REPORT INCLUDES
  • 56 data tables and 65 additional tables
  • An overview of the global markets and expected consumption for immunohistochemistry (IHC) technologies
  • Analyses of global market trends, with data from 2016 and 2017, and projections of compound annual growth rates (CAGRs) through 2022
  • Coverage of major trends and challenges that affect the market and the supplier landscape
  • End-use industry coverage, including hospitals and diagnostic laboratories, and research institutes
  • Evaluation of the market's dynamics, including growth drivers and restraints
  • Company profiles of major players in the market, including Abbott Laboratories, Abcam, Abnova, Danaher Corp. and PeproTech GmbH
SUMMARY

Immunohistochemistry (IHC) is an umbrella term which combines immunological, biochemical and anatomical techniques to image and localize discrete components in tissues with the help of antibodiesantigen interaction. The use of IHC helps in the documentation and visualization of the high-resolution distribution of cellular components and localization of the antigens of the cells within their proper histological context. The unique properties of IHC testing to precisely localize the antigens, identify the cell type and the tumor, has leveraged its wide adoption in diagnosis, drug development and biological research. IHC tests are employed as a confirmatory procedure or a primary tool for the diagnosis of
various diseases including cancer, cardiovascular, infectious and other diseases.

The author reached out to many industry contacts, including Chris La Placa, who is a histotechnologist at BIO SB Inc. Chris has many years of hands-on experience, so it is instructive that he says Quote: “I agree that the value of the IHC industry is growing and will continue to grow in the coming years. Many pathologists have previously used more basic tissue stains to identify entire structures within human tissue, but IHC is an advantage as it can identify individual proteins. Its application in diagnosing infectious diseases such as syphilis and tuberculosis is also growing in popularity. My company distributes primary antibodies with specificity for bacteria such as H. pylori, T. pallidum, T. gondii, and P. jirovecii (among many others), and these are some of our top sellers. Additionally, we manufacture and sell anchorage dependent cell lines embedded and mounted to a slide that can be stained by IHC. These can be used as controls for validation of patient tissues and are of great interest to pathologists around the world.”

Continuous technology and methodological improvements adds value to this type of field especially, where small details and time savings make can make a big difference. For Peter Rauch an MD at Candor Bioscience GMBH we asked which immunoassay solution is the most widely adopted immunoassay in their operating region?

Quote: “For us it is the ELISA market, where we sell most of our products, including the wide range of commercial diagnostic ELISA.” Understanding regional variations can be an effective way to optimize business approaches in a fast changing landscape.

The global Immunohistochemistry market is projected to rise at a CAGR of REDACTED during the forecast period of 2017 through 2022. In 2022, total revenues are expected to reach more than REDACTED,registering an increment from REDACTED in 2017.

The report provides an analysis based on each market segment which includes products, applications and end users. The product segment is further sub-segmented into IHC antibodies, reagents, kits and equipment. The antibodies held the largest market share of REDACTED in 2017 in terms of revenue followed by reagents, equipment and kits. By 2022, total revenue from the antibodies segment is expected toreach more than REDACTED. Whereas, the reagents segment is estimated to rise at the highest CAGR of REDACTED through 2022. Total revenue from the reagents segment is expected to reach REDACTED million by 2022.
CHAPTER 1 INTRODUCTION

Study Goals and Objectives
Definition of Immunohistochemistry
Scope of Report
Intended Audience
Research Methodology and Information Sources
Analyst's Credentials
Related BCC Research Reports

CHAPTER 2 SUMMARY AND HIGHLIGHTS

CHAPTER 3 MARKET AND TECHNOLOGY BACKGROUND

History of Immunohistochemistry
Regulations and Standards of the Immunohistochemistry Market
U.S. Food and Drug Administration
Equipment in the Immunohistochemistry Market
Raw Material Suppliers
Equipment Manufacturers
Distributors
End Users
Factors Affecting the Immunohistochemistry Equipment Market
Reagents in the Immunohistochemistry Market
Raw Material Suppliers
Reagent Manufacturers
Distributors
End Users
Factors Affecting the Immunohistochemistry Reagent Market
Antibodies in the Immunohistochemistry Market
Manufacturers of Antibodies Used in the Immunohistochemistry Market
Segmentation by Product
Antibodies
Equipment
Reagents
Segmentation by Application
Diagnostics
Drug Testing
Segmentation by End User
Hospital and Diagnostics Laboratories
Research Institutes
Other (Contract Research Organization and Forensic Laboratories)
Segmentation by Region
North America
Europe
Asia-Pacific
South America
Rest of the World

CHAPTER 4 MARKET BREAKDOWN BY PRODUCT

Antibodies
Primary Antibodies
Secondary Antibodies
Equipment
Slide Staining Systems
Tissue Microarrays
Tissue Processing Systems
Slide Scanners
Other Equipment (Microtome, Water Bath, pH Meter, etc.)
Reagents
Histological Stains
Blocking Sera and Reagents
Chromogenic Substrates
Fixation Reagents
Stabilizers
Organic Solvents
Proteolytic Enzymes
Diluents
Kits

CHAPTER 5 MARKET BREAKDOWN BY APPLICATION

Diagnostics
The Process of Immunohistochemistry in Diagnoses
Cancer Diagnostics
Infectious Diseases
Cardiovascular Disease
Autoimmune Diseases
Diabetes Mellitus
Nephrological Diseases
Drug Testing

CHAPTER 6 MARKET BREAKDOWN BY END USER

Hospitals and Diagnostic Laboratories
Research Institutes
Other End Users

CHAPTER 7 MARKET BREAKDOWN BY REGION

North America
United States
Canada
Europe
United Kingdom
France
Germany
Spain
Rest of Europe
Asia-Pacific
China
India
Japan
Australia
Rest of Asia-Pacific
Latin America
Brazil
Mexico
Argentina
Chile
Cuba
Middle East and Africa

CHAPTER 8 MARKET DRIVERS

Impact Analysis
Growing Prevalence of Cancer
Rapidly Increasing Geriatric Population
Rapid Technological Developments in the IVD Industry
Increasing Healthcare Spending

CHAPTER 9 COMPANY PROFILES AND VENDOR LANDSCAPE

ABBOTT LABORATORIES
ABCAM
ABNOVA
AGILENT TECHNOLOGIES INC.
ARRAYIT CORP.
BIO SB
BIOCARE MEDICAL
BIOGENEX
BIOLEGEND
BIO-RAD LABORATORIES INC.
CANDOR BIOSCIENCE GMBH
CELL MARQUE CORP.
CELL SIGNALING TECHNOLOGY INC.
DANAHER CORP.
DIAGNOSTIC BIOSYSTEMS INC.
F. HOFFMANN-LA ROCHE AG
HISTOLOGIX
IMMUNOLOGIC
LSBIO
MERCK MILLIPORE
NOVODIAX
PEPROTECH GMBH
PERKINELMER INC.
ROCKLAND IMMUNOCHEMICALS
SAKURA FINETEK USA INC.
SIEMENS AG HEALTHCARE
THERMO FISHER SCIENTIFIC INC.
VECTOR LABORATORIES

LIST OF TABLES

Summary Table: Global Immunohistochemistry Market, by Product, Through 2022
Table 1: Immunohistochemistry Laboratory Standards and Regulations
Table 2: U.S. Centers for Disease Control Biosafety Regulations
Table 3: Antibody Manufacturers and Products Available in the Global Immunohistochemistry Market
Table 4: Global Immunohistochemistry Market, by Product, Through 2022
Table 5: Global Immunohistochemistry Market, by Antibodies, Through 2022
Table 6: Diabetes Incidence in the Top 10 Countries, 2016
Table 7: Global Antibodies Market, by Region, Through 2022
Table 8: Global Primary Antibodies Market, by Region, Through 2022
Table 9: Examples of Clinically Important Monoclonal Antibodies
Table 10: Secondary Antibody Selection
Table 11: Global Secondary Antibodies Market, by Region, Through 2022
Table 12: Global Immunohistochemistry Market, by Equipment, Through 2022
Table 13: Global Immunohistochemistry Equipment Market, by Region, Through 2022
Table 14: Global Slide Staining Systems Market, by Region, Through 2022
Table 15: Estimated Number of U.S. Cancer Survivors, by Sex and Survival Years, as of Jan. 1, 2016
Table 16: Global Tissue Microarrays Market, by Region, Through 2022
Table 17: Healthcare Spending by Different Income Level Countries, 2040
Table 18: Global Tissue Processing Systems Market, by Region, Through 2022
Table 19: Global Slide Scanners Market, by Region, Through 2022
Table 20: Global Other Equipment Market, by Region, Through 2022
Table 21: Global Immunohistochemistry Market, by Reagent, Through 2022
Table 22: Global Reagents Market, by Region, Through 2022
Table 23: Global Histological Stains Market, by Region, Through 2022
Table 24: Categories of Histological Stains
Table 25: Global Blocking Sera and Reagents Market, by Region, Through 2022
Table 26: Global Chromogenic Substrates Market, by Region, Through 2022
Table 27: Global Fixation Reagents Market, by Region, Through 2022
Table 28: Most Common Fixatives and Their General Target Antigens
Table 29: Global Stabilizers Market, by Region, Through 2022
Table 30: The Most Common Causes of Cancer Death, 2015
Table 31: Global Organic Solvents Market, by Region, Through 2022
Table 32: Global Proteolytic Enzymes Market, by Region, Through 2022
Table 33: Global Diluents Market, by Region, Through 2022
Table 34: Kit Components for Immunohistochemistry Optimization
Table 35: Global IHC Kits Market, by Region, Through 2022
Table 36: Global Immunohistochemistry Market, by Application, Through 2022
Table 37: Global Immunohistochemistry Diagnostics Market, by Application, Through 2022
Table 38: Global Immunohistochemistry Diagnostics Market, by Region, Through 2022
Table 39: Global Cancer Diagnostics Market, by Region, Through 2022
Table 40: Global Immunohistochemistry Infectious Disease Applications Market, by Region, Through 2022
Table 41: Global Immunohistochemistry Cardiovascular Disease Applications Market, by Region, Through 2022
Table 42: Selected Infectious Etiologies of Autoimmune Diseases
Table 43: Global Immunohistochemistry Autoimmune Disease Applications Market, by Region, Through 2022
Table 44: Diabetes Incidence in the Top 10 Countries, 2016
Table 45: Global Immunohistochemistry Diabetes Mellitus Applications Market, by Region, Through 2022
Table 46: Global Immunohistochemistry Nephrological Disease Applications Market, by Region, Through 2022
Table 47: Global Immunohistochemistry Drug Testing Applications Market, by Region, Through 2022
Table 48: Global Immunohistochemistry Market, by End User, Through 2022
Table 49: Global Immunohistochemistry Hospital and Diagnostic Laboratory Applications Market, by Region, Through 2022
Table 50: Various Cancer Research Studies
Table 51: Global Immunohistochemistry Research Institute Applications Market, by Region, Through 2022
Table 52: Uses of Immunohistochemistry in Forensic Pathology
Table 53: Global Immunohistochemistry Other End User Applications Market, by Region, Through 2022
Table 54: Global Immunohistochemistry Market, by Region, Through 2022
Table 55: Grants by Type of Cancer, 2017
Table 56: Estimated New Cancer Cases in Males in Canada, 2017
Table 57: Estimated New Cancer Cases in Females in Canada, 2017
Table 58: Deaths from CVD and Number of People Living with CVD in the U.K., 2017
Table 59: Death Rate Due to Cardiovascular Diseases in the U.K., 2017
Table 60: Deaths Caused by Cardiovascular Disease Compared with Other Causes of Death in Germany, 2016
Table 61: Diseases Causing the Greatest Number of Premature Deaths in Germany, Percentage Change from 2005-2016
Table 62: Cancer Incidence Rates in Asia-Pacific, 2016
Table 63: Mortality Rates in Asia-Pacific, by Cancer Type, 2016
Table 64: Top Five Types Cancer in Men and Women in India, 2017
Table 65: Estimated Incidence of All Cancers in Australia, by Sex, 2017
Table 66: Estimated 20 Most Commonly Diagnosed Cancers in Males in Australia, 2017
Table 67: Estimated 20 Most Commonly Diagnosed Cancers in Females in Australia, 2017
Table 68: 10 Most Common Cancers in Australia Considering Principal Diagnosis, 2014–2015 (Number/%)
Table 69: Estimated 10 Most Common Causes of Death from Cancer in Males in Australia, 2017
Table 70: Estimated 10 Most Common Causes of Death from Cancer in Females in Australia, 2017
Table 71: Percentage of Population in Brazil, Age 60 and Above
Table 72: Top 10 Causes of Death in Mexico and Percentage Increase from 2005–2016
Table 73: Top 10 Causes of Death in Argentina and Percentage Change, 2005-2016
Table 74: Top 10 Causes of Death in Cuba and Percentage Change, 2005-2016
Table 75: Impact Analysis of Market Drivers
Table 76: Cancer Markers Used in the Diagnosis and Treatment of Different Types of Cancer
Table 77: Global Population Aged 60 Years and Above, by Region
Table 78: Global Population Aged 80 Years and Above, by Region
Table 79: Countries with the Highest Elderly Populations, 2015 and 2030
Table 80: Abbott Laboratories: Product Portfolio
Table 81: Abcam: Product Portfolio
Table 82: Abcam Recent Developments, 2015-2018
Table 83: Abnova: Product Portfolio
Table 84: Agilent Technologies Inc.: Product Portfolio
Table 85: Agilent Technologies Inc. Recent Developments, 2015-2018
Table 86: Arrayit Corp.: Product Portfolio
Table 87: Arrayit Corp. Recent Developments, 2015-2018
Table 88: Bio SB: Product Portfolio
Table 89: Bio SB Recent Developments, 2015-2018
Table 90: Biocare Medical: Product Portfolio
Table 91: Biocare Medical Recent Developments, 2015-2018
Table 92: Biogenex: Product Portfolio
Table 93: Biogenex Recent Developments, 2015-2018
Table 94: BioLegend: Product Portfolio
Table 95: Bio-Rad Laboratories Inc.: Product Portfolio
Table 96: Candor Bioscience Gmbh: Product Portfolio
Table 97: Cell Marque Corp.: Product Portfolio
Table 98: Cell Signaling Technology Inc.: Product Portfolio
Table 99: Cell Signaling Technology Inc.Recent Developments, 2015-2018
Table 100: Danaher Corp.: Product Portfolio
Table 101: Danaher Corp. Recent Developments, 2015-2018
Table 102: Diagnostic Biosystems Inc.: Product Portfolio
Table 103: F. Hoffmann-La Roche Ag: Product Portfolio
Table 104: F. Hoffmann-La Roche Ag Recent Developments, 2015-2018
Table 105: Histologix: Product Portfolio
Table 106: Immunologic: Product Portfolio
Table 107: LSBio: Product Portfolio
Table 108: Merck Millipore: Product Portfolio
Table 109: Novodiax: Product Portfolio
Table 110: Novodiax Recent Developments, 2015-2018
Table 111: PeproTech Gmbh: Product Portfolio
Table 112: Perkinelmer Inc.: Product Portfolio
Table 113: Rockland Immunochemicals: Product Portfolio
Table 114: Sakura Finetek Usa Inc.: Product Portfolio
Table 115: Sakura Finetek Usa Inc. Recent Developments, 2015-2018
Table 116: Siemens AG Healthcare: Product Portfolio
Table 117: Thermo Fisher Scientific Inc.: Product Portfolio
Table 118: Thermo Fisher Scientific Inc. Recent Developments, 2015-2018
Table 119: Vector Laboratories: Product Portfolio
Table 120: Vector Laboratories Recent Developments, 2015-2018

LIST OF FIGURES

Summary Figure: Global Market for Immunohistochemistry, by Product, 2016-2022
Figure 1: Outline of The Steps Needed to Localize Antigens in IHC Testing
Figure 2: Immunohistochemistry Timeline
Figure 3: Immunohistochemistry Test Procedure
Figure 4: Global Immunohistochemistry Market Shares, by Product, 2016 and 2022
Figure 5: Phases of Histological Staining
Figure 6: Global Immunohistochemistry Market Shares, by Application, 2016 and 2022
Figure 7: Global Immunohistochemistry Market Shares, by End User, 2016 and 2022
Figure 8: Global Immunohistochemistry Market Shares, by Region, 2016 and 2022
Figure 9: Global Immunohistochemistry Market Shares, by Product, 2016 and 2022
Figure 10: Number of Cancer Cases Worldwide, 2012 and 2030
Figure 11: Number of People with Chronic Conditions in the United States, 2010-2025
Figure 12: Percentage Distribution of Population Aged 65 and Over, by Region, 2015 and 2050
Figure 13: Global Immunohistochemistry Market Share, by Service, 2016
Figure 14: Number of New TB Cases, 2016
Figure 15: New HIV Diagnoses in the United States, by Age, 2016
Figure 16: Estimated Number of Colon Cancer Cases in the U.S, 2017 and 2018
Figure 17: Global Immunohistochemistry Market Shares, by Application, 2016 and 2022
Figure 18: Global Prevalence of Colon Cancer, by Age, 2016
Figure 19: New Global HIV Infections, by Region, 2016
Figure 20: Healthcare Expenditures Across the Globe, 2014-2016
Figure 21: Healthcare Cost Comparison of Autoimmune Diseases and Cancer, 2015
Figure 22: Global Prevalence of Diabetes, by Age Group and Region
Figure 23: Global Prevalence of Chronic Kidney Diseases, by Age
Figure 24: Global Development of Medicines, by Disease Type
Figure 25: Global Share of R&D Spending on Drug Testing, by Region, 2016
Figure 26: Global Immunohistochemistry Market Shares, by End User, 2016 and 2022
Figure 27: Global Incidence of Patients with Chronic Diseases, 2005-2030
Figure 28: New Cases of Cancer in France, 2015
Figure 29: Health Spending and Financing in France, 2005-2015
Figure 30: Market Demand for Medical Equipment in France
Figure 31: Healthcare Spending in Mexico, 2014 and 2040
Figure 32: Healthcare Spending in Argentina, 2014 and 2040
Figure 33: Healthcare Expenditures and Financing in Chili, 2005-2016
Figure 34: Healthcare Spending in Cuba, 2014 and 2040
Figure 35: Global GDP Shares of Healthcare Expenditures and Financing, by Country 2010-2016


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