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Bone Grafts And Substitutes Market Size, Share & Trends Analysis Report By Material Type (Allograft, Synthetic), By Application (Dental, Spinal Fusion), By Region, And Segment Forecasts, 2025 - 2030

October 2024 | 150 pages | ID: BDF48407195EN
Grand View Research, Inc.

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Bone Grafts And Substitutes Market Growth & Trends

The global bone grafts and substitutes market size is expected treach USD 4.54 billion by 2030, registering tgrow at a CAGR of 6.6% from 2025 t2030 according ta new report by Grand View Research, Inc. The increasing prevalence of orthopedic disorders and surge in number of orthopedic surgeries are likely tdrive the market growth. In addition, technological advancements in developing advanced orthopedic grafts & substitutes and rising investments by leading players tmeet increasing global demand for advanced grafts have further escalated the industry expansion.

Increasing demand for developing biocompatible bone grafts treduce adverse reactions is driving the market. Increasing use of synthetic bone grafts with Hydroxyapatite and Tricalcium Phosphate, which has shown better biocompatibility as compared tothers, is fueling the market growth. Market players are continuously developing new products with better biocompatibility, bioactivity, and suitable mechanical properties. For instance, in October 2020, Graftys received Medical Device Single Audit Program (MDSAP) certification for its Sterile Calcium Phosphate Resorbable Bone Void Fillers and related delivery systems in Australia, Brazil, Canada, and U.S. It alsreceived CE recertification in Europe.

The increasing use of bone grafts in density is propelling the growth of dental bone grafts and substitutes market. The bone grafts are mostly used as a scaffold and filler tfacilitate bone formation and promote healing. Dental implant surgery has now become very popular with advanced surgical techniques such as bone grafts and bone regeneration. Moreover, increasing demand and success rates of dental implants are fueling market growth. According tthe American Academy of Implant Dentistry, as of 2020, the number of people getting dental implants has risen by 500,000 annually. The source alsreported a success rate of 95% in the implant dentistry segment. Around 5 million implant procedures are performed in the U.S. every year.

Synthetic bone graft technology is benefiting advanced medicine, but the cost of such technologies is high, thus restraining market growth. The average price of DBM ranges from USD 600 tUSD 865; that of bone morphogenetic protein matrix ranges from USD 3,450 tUSD 5,000, and of synthetic ceramic & polymer-based bone grafts ranges from USD 893 tUSD 2,000. In addition, reimbursement policies vary based on autografts and bone graft substitutes used, which increase the cost of procedures. This helps avoid incisions and difficulty in obtaining donor grafts. Therefore, the high cost of associated devices and technologies may hinder market growth.

Bone Grafts And Substitutes Market Report Highlights
        • Based on material type, the allograft segment held the largest revenue share of 60.2% in 2024 and is anticipated twitness significant growth opportunities during the forecast period. The allograft adoption is significantly increasing owing tits properties such as osteoconductivity, and immediate structural support. The synthetic segment is projected texhibit the fastest growth over the forecast period
    • Based on application, the spinal fusion sub-segment held the largest market share in 2024. The increasing adoption of bone graft materials for spondylosyndesis and rising geriatric population prone ta number of orthopedic ailments are responsible for the higher revenue share of the segment
    • North America dominated the global bone grafts and substitutes market in 2024 and is projected tbe the leading revenue contributor during the forecast period. The rising geriatric population and increasing incidence of sports injuries & fatal accidents are among the key factors boosting the demand for bone grafts and substitutes in North America
  • Some of the leading players include Smith & Nephew, Medtronic, and DePuy Synthes, as they have maintained their market position during the forecast period in terms of product penetration, regional presence, revenue, as well as strategic initiatives.
CHAPTER 1 RESEARCH METHODOLOGY & SCOPE

1.1 Market Segmentation & Scope
  1.1.1 Estimates and Forecast Timeline
1.2 Research Methodology
1.3 Information Procurement
  1.3.1 Purchased database:
  1.3.2 GVR’s Internal Database
  1.3.3 Secondary sources
  1.3.4 Primary Research:
  1.3.5 Details of Primary Research
1.4 Information or Data Analysis
  1.4.1 Data Analysis Models
1.5 Market Formulation & Validation
1.6 Model Details
1.7 List of Secondary Sources
1.8 List of Primary Sources
1.9 Abbreviations
1.10 Report Objectives

CHAPTER 2 EXECUTIVE SUMMARY

2.1 Market Outlook
2.2 Segment Outlook
  2.2.1. Material type outlook
  2.2.2. Application outlook
  2.2.3. Regional outlook
2.3 Competitive Insights

CHAPTER 3 BONE GRAFTS & SUBSTITUTES MARKET VARIABLES, TRENDS & SCOPE

3.1 Regulatory Framework
3.2 USFDA Consideration
  3.2.1 Bone grafts & substitutes that are found to be medically necessary
3.3 Reimbursement framework
  3.3.1 CPT Coding
  3.3.2 HCPCS Coding
  3.3.3 Market driver analysis
    3.3.3.1 Rising incidence of bone & joint disorders
    3.3.3.2 Advent of biocompatible synthetic graft
    3.3.3.3 Rising demand for dental bone grafts
    3.3.3.4 Technological advancement
    3.3.3.5 Rising geriatric population
  3.3.4 Market restraint analysis
    3.3.4.1 Stringent regulatory guidelines
    3.3.4.2 Risk of disease transmission
    3.3.4.3 High cost of bone grafts and substitutes
3.4 Bone Grafts & Substitutes Market Analysis Tools: Porter’s
3.5 PESTEL Analysis
3.6 Estimated Market Volume, By Material Type, Global & Regional, 2018-2030
3.7 Pricing Analysis, By Material Type

CHAPTER 5 BONE GRAFTS & SUBSTITUTES MARKET: MATERIAL TYPE ESTIMATES & TREND ANALYSIS

5.1 Material Type Dashboard
  5.1.1 Allograft
    5.1.1.1 Allograft market estimates and forecasts, 2018 - 2030 (USD Million)
    5.1.1.2 Demineralized Bone Matrix (DBM)
      5.1.1.2.1. Demineralized Bone Matrix (DBM) market estimates and forecasts, 2018 - 2030 (USD Million)
    5.1.1.3 Others
      5.1.1.3.1 Others market estimates and forecasts, 2018 - 2030 (USD Million)
  5.1.2 Synthetic
    5.1.2.1 Synthetic market estimates and forecasts, 2018 - 2030 (USD Million)
    5.1.2.2 Ceramic
      5.1.2.2.1 Ceramic market estimates and forecasts, 2018 - 2030 (USD Million)
      5.1.2.2.2 HAP
        5.1.2.2.2.1 HAP market estimates and forecasts, 2018 - 2030 (USD Million)
      5.1.2.2.3 Я-TCP
        5.1.2.2.3.1 Я-TCP market estimates and forecasts, 2018 - 2030 (USD Million)
      5.1.2.2.4 ?lpha-tricalcium phosphate (?lpha-TCP)
        5.1.2.2.4.1 ?lpha-TCP market estimates and forecasts, 2018 - 2030 (USD Million)
      5.1.2.2.5 Bi-phasic calcium phosphates (BCP)
        5.1.2.2.5.1 Bi-phasic calcium phosphates (BCP) market estimates and forecasts, 2018 - 2030 (USD Million)
      5.1.2.2.6 Others
        5.1.2.2.6.1 Others market estimates and forecasts, 2018 - 2030 (USD Million)
    5.1.2.3 Composite
      5.1.2.3.1 Composite market estimates and forecasts, 2018 - 2030 (USD Million)
    5.1.2.4 Polymers
      5.1.2.4.1 Polymers market estimates and forecasts, 2018 - 2030 (USD Million)
    5.1.2.5 BMP
      5.1.2.5.1 BMP market estimates and forecasts, 2018 - 2030 (USD Million)

CHAPTER 6 BONE GRAFTS & SUBSTITUTES MARKET: APPLICATION ESTIMATES & TREND ANALYSIS

6.1. Application Dashboard
6.2 Craniomaxillofacial
  6.2.1 Craniomaxillofacial market estimates and forecasts, 2018 - 2030 (USD Million)
6.3 Dental
  6.3.1 Dental market estimates and forecasts, 2018 - 2030 (USD Million)
6.4 Foot & Ankle
  6.4.1 Foot & Ankle market estimates and forecasts, 2018 - 2030 (USD Million)
6.5 Joint Reconstruction
  6.5.1 Joint Reconstruction market estimates and forecasts, 2018 - 2030 (USD Million)
6.6 Long Bone
  6.6.1 Long Bone market estimates and forecasts, 2018 - 2030 (USD Million)
6.7 Spinal Fusion
  6.7.1 Spinal Fusion market estimates and forecasts, 2018 - 2030 (USD Million)

CHAPTER 7 BONE GRAFTS & SUBSTITUTES MARKET: REGIONAL ESTIMATES & TREND ANALYSIS, BY, MATERIAL TYPE, & APPLICATION

7.1 Regional Market Snapshot
7.2 North America
  7.2.1 North America Bone Grafts & Substitutes Market estimates and forecasts, 2018 - 2030 (USD Million)
  7.2.2 U.S.
    7.2.2.1 U.S. Bone Grafts & Substitutes Market estimates and forecasts, 2018 - 2030 (USD Million)
  7.2.3 Canada
    7.2.3.1 Canada Bone Grafts & Substitutes Market estimates and forecasts, 2018 - 2030 (USD Million)
7.3 Europe
  7.3.1 Europe Bone Grafts & Substitutes Market estimates and forecasts, 2018 - 2030 (USD Million)
  7.3.2 UK
    7.3.2.1 UK Bone Grafts & Substitutes Market estimates and forecasts, 2018 - 2030 (USD Million)
  7.3.3 Germany
    7.3.3.1 Germany Bone Grafts & Substitutes Market estimates and forecasts, 2018 - 2030 (USD Million)
  7.3.4 France
    7.3.4.1 France Bone Grafts & Substitutes Market estimates and forecasts, 2018 - 2030 (USD Million)
  7.3.5 Italy
    7.3.5.1 Italy Bone Graft and Substitutes Market, 2018 - 2030 (USD Million)
  7.3.6 Spain
    7.3.6.1 Spain Bone Graft and Substitutes Market, 2018 - 2030 (USD Million)
  7.3.7 Denmark
    7.3.7.1 Denmark Bone Graft and Substitutes Market, 2018 - 2030 (USD Million)
  7.3.7 Norway
    7.3.7.1 Norway Bone Graft and Substitutes Market, 2018 - 2030 (USD Million)
  7.3.9 Sweden
    7.3.9.1 Sweden Bone Graft and Substitutes Market, 2018 - 2030 (USD Million)
7.4 Asia Pacific
  7.4.1 Asia Pacific Bone Grafts & Substitutes Market estimates and forecasts, 2018 - 2030 (USD Million)
  7.4.2 China
    7.4.2.1 China Bone Graft and Substitutes Market, 2018 - 2030 (USD Million)
  7.4.3 Japan
    7.4.3.1 Japan Bone Graft and Substitutes Market, 2018 - 2030 (USD Million)
  7.4.4 India
    7.4.4.1 India Bone Graft and Substitutes Market, 2018 - 2030 (USD Million)
  7.4.5 South Korea
    7.4.5.1 South Korea Bone Graft and Substitutes Market, 2018 - 2030 (USD Million)
  7.4.6 Australia
    7.4.6.1 Australia Bone Graft and Substitutes Market, 2018 - 2030 (USD Million)
7.5 Latin America
  7.5.1 Latin America Bone Grafts & Substitutes Market estimates and forecasts, 2018 - 2030 (USD Million)
  7.5.2 Mexico
    7.5.2.1 Mexico Bone Grafts & Substitutes Market estimates and forecasts, 2018 - 2030 (USD Million)
  7.5.3 Brazil
    7.5.3.1 Brazil Bone Grafts & Substitutes Market estimates and forecasts, 2018 - 2030 (USD Million)
  7.5.2 Mexico
    7.5.2.1 Mexico Bone Grafts & Substitutes Market estimates and forecasts, 2018 - 2030 (USD Million)
  7.5.4 Argentina
    7.5.4.1 Argentina Bone Grafts & Substitutes Market estimates and forecasts, 2018 - 2030 (USD Million)
7.6 MEA
  7.6.1 MEA Bone Grafts & Substitutes Market estimates and forecasts, 2018 - 2030 (USD Million)
  7.6.2 South Africa
    7.6.2.1 South Africa Bone Grafts & Substitutes Market estimates and forecasts, 2018 - 2030 (USD Million)
  7.6.3 Saudi Arabia
    7.6.3.1 Saudi Arabia Bone Grafts & Substitutes Market estimates and forecasts, 2018 - 2030 (USD Million)
  7.6.4 UAE
    7.6.4.1 UAE Bone Grafts & Substitutes Market estimates and forecasts, 2018 - 2030 (USD Million)
  7.6.5 Kuwait
    7.6.5.1 Kuwait Bone Grafts & Substitutes Market estimates and forecasts, 2018 - 2030 (USD Million)

CHAPTER 8 COMPANY PROFILES

8.1. Recent Developments & Impact Analysis, By Key Market Participants
8.2. Company Categorization
8.3 AlloSource
  8.3.1 Company overview
  8.3.2 Financial Performance
  8.3.3 Product benchmarking
  8.3.4 Strategic Initiatives
8.4 Baxter
  8.4.1 Company overview
  8.4.2 Financial Performance
  8.4.3 Product benchmarking
  8.4.4 Strategic Initiatives
8.5 DePuy Synthes
  8.5.1 Company overview
  8.5.2 Financial Performance
  8.5.3 Product benchmarking
  8.5.4 Strategic Initiatives
8.6 Medtronic
  8.6.1 Company overview
  8.6.2 Financial Performance
  8.6.3 Product benchmarking
  8.6.6 Strategic Initiatives
8.7 NuVasive, Inc.
  8.7.1 Company overview
  8.7.2 Financial Performance
  8.7.3 Product benchmarking
  8.7.4 Strategic Initiatives
8.8 Orthofix Medical, Inc.
  8.8.1 Company overview
  8.8.2 Financial Performance
  8.8.3 Product benchmarking
  8.8.4 Strategic Initiatives
8.9 Smith + Nephew
  8.9.1 Company overview
  8.9.2 Financial Performance
  8.9.3 Product benchmarking
  8.9.4 Strategic Initiatives
8.10 Stryker
  8.10.1 Company overview
  8.10.2 Financial Performance
  8.10.3 Product benchmarking
  8.10.4 Strategic Initiatives
8.11 Biobank
  11.11.1 Company overview
  11.11.2 Financial Performance
  11.11.3 Product benchmarking
  11.11.4 Strategic Initiatives
8.12 OST Laboratories
  8.12.1 Company overview
  8.12.2 Financial Performance
  8.12.3 Product benchmarking
  8.12.4 Product benchmarking
8.13 Zimmer Biomet
  8.13.1 Company overview
  8.13.2 Financial performance
  8.13.3 Product benchmarking
  8.13.4 Strategic initiatives
8.14 Geistlich Pharma AG
  8.14.1 Company overview
  8.14.2 Financial performance
  8.14.3 Product benchmarking
  8.14.4 Strategic initiatives


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