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Induced Pluripotent Stem Cells: Global Markets

June 2021 | 142 pages | ID: I9A46DFC02FEN
BCC Research

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Report Scope

This study focuses on the market side of iPSCs rather than its technical side. Different market segments for this emerging market are covered. For instance, product function-based market segments include molecular and cellular engineering, cellular reprogramming, cell culture, cell differentiation, and cell analysis. Application-based market segments include drug development and toxicity testing, academic research, and regenerative medicine. iPSC-derived cell-type-based market segments include hepatocytes, neurons, cardiomyocytes, endothelial cells, and other cell types. Other cell types are comprised of astrocytes, fibroblasts, hematopoietic progenitor cells, etc. Geographical-based market segments include the U.S., Asia-Pacific, Europe, and the Rest of the World. The research and market trends are also analyzed by studying the funding, patent publications and research publications in the field.

This report focuses on the market size and segmentation of iPSC products, including iPSC research and clinical products. The market for iPSC-related contract services is also discussed. iPSC research products are defined as all research tools, including iPSCs and various differentiated cells derived from iPSCs, various related assays and kits, culture media and medium components (e.g., serum, growth factors, inhibitors), antibodies, enzymes, and products that can be applied for the specific purpose of executing iPSC research. For this report, iPSC products do not cover stem cell research and clinical products, which are broadly applicable to any stem cell type.

This report discusses key manufacturers, technologies and factors influencing market demand, including the driving forces and limiting factors of the iPSCs market growth. Based on these facts and analysis, the market trends and sales for research and clinical applications are forecast through 2026. One particular focus on the application of iPSCs was given to drug discovery and development, which includes pharmaco-toxicity screening, lead generation, target identification, and other preclinical studies, body-on-a-chip, and 3D disease modeling. Suppliers and manufacturers of iPSC-related products are discussed and analyzed based on their market shares, product types, and geography. An in-depth patent analysis and research funding analysis are also included to assess the overall direction of the iPSCs market.

The detailed technologies such as those for generating iPSCs, differentiating iPSCs, controlling the differentiation, and large-scale manufacturing of iPSCs and their derivative cells under GMP compliance or xeno-free conditions are excluded from the study, as they are beyond the scope of this report.

Report Includes
  • 43 tables
  • An updated review of the global market for induced pluripotent stem cells (iPSC) within the industry
  • Analyses of the global market trends, with data from 2020, estimates for 2021 and projections of compound annual growth rates (CAGRs) through 2026
  • Estimation of the market size and revenue forecast for the iPSCs market, and corresponding market share analysis by market segments such as application, reprogramming method, iPSCs generation method, product function and geography
  • Highlights of emerging technology trends, market opportunities and deterrents estimating current and future demand of iPSC-related products and their derivatives for drug discovery
  • Identification of the companies that are best positioned to meet this demand because of their proprietary technologies, strategic alliances, or other advantages
  • Discussion of market dynamics that impact the growth of the market for iPSCs, clinical applications, market regulations, industry structure, and penetration of technologies within the biotech industry
  • Insight into the segmentation of iPSC products, including iPSC research and clinical products, along with application-based segments such as academic research, drug development and regenerative medicine as well as iPSC-related contract services
  • Number of global (+ the U.S.) patents and patent applications on induced pluripotent stem cells, and corresponding iPSC scientific publications during the period of 2008-October 2019
  • Competitive landscape of the key manufacturers and suppliers in the iPSC market, their competitive environment and major growth strategies within the global market
  • Descriptive company profiles of leading industry players, including Applied Biological Materials Inc., Bristol-Myers Squibb, Corning Inc., Merck KGaA and Thermo Fisher Scientific
CHAPTER 1 INTRODUCTION

Study Goals and Objectives
Reasons for Doing This Study
Scope of Report
Information Sources
Methodology
Geographic Breakdown
Analyst’s Credentials
BCC Custom Research
Related BCC Research Reports

CHAPTER 2 SUMMARY AND HIGHLIGHTS

Key Drivers for Market Growth

CHAPTER 3 MARKET OVERVIEW

Introduction
History and Current State
Evolution of Induced Pluripotent Stem Cell Research
Advantages and Disadvantages of Induced Pluripotent Stem Cells
Advantages
Disadvantages
Technology Overview
Induced Pluripotent Stem Cell Generation
Induced Pluripotent Stem Cell Differentiation
Current Challenges to iPSC Applications
iPSCs Bank

CHAPTER 4 IMPACT OF COVID-19 PANDEMIC

Introduction
Impact on MedTech
Elective and Noncritical Procedures
Shift in Manufacturing
Regulatory Delays, Clinical Trials and Product Launches
Supply Chain Disruptions
Medical Tourism
Impact of COVID-19 on iPSCs
Pluripotent Stem Cells as a Study Model for COVID-19
Scientists Use Stem Cells to Uncover COVID-19 Effects on the Heart

CHAPTER 5 INDUCED PLURIPOTENT STEM CELL APPLICATIONS

Academic Research
Pharmaco-Toxicological Screening
Drug Discovery and Development
Disease Modeling
Tissue Engineering
Cell Therapy

CHAPTER 6 INDUCED PLURIPOTENT STEM CELLS MARKET SEGMENTATION AND FORECAST

Market Overview
U.S.
Europe
Asia-Pacific
Application-Based Market Overview
Induced Pluripotent Stem Cells Product Market
Induced Pluripotent Stem Cell-Derived Tissue Cell Market
Induced Pluripotent Stem Cells and Their Derivative Cell Market by Species
Global Market
Major Suppliers and Manufacturers of Induced Pluripotent Stem Cell Products
Market for Induced Pluripotent Stem Cell-Derived Cells by Application
Market for Induced Pluripotent Stem Cells by Product Function
Global Market
Regional Markets
Research Market Compared with the Clinical Market

CHAPTER 7 INDUCED PLURIPOTENT STEM CELLS RESEARCH APPLICATION MARKET

Induced Pluripotent Stem Cells Research Product Types
Major Players
Major Commercial Entities
Major Noncommercial Organizations
Market Shares and Projections

CHAPTER 8 INDUCED PLURIPOTENT STEM CELL CONTRACT SERVICE MARKET

Induced Pluripotent Stem Cell Contract Service Types
Major Players
Market Shares and Projections

CHAPTER 9 RESEARCH MARKET TREND ANALYSIS

Grant Analysis
Patent Analysis
Scientific Publication Analysis

CHAPTER 10 CLINICAL APPLICATION MARKET TREND ANALYSIS

Clinical Trials
Age-Related Macular Degeneration
Ischemic Heart Disease
Parkinson’s Disease
Graft-versus-Host Disease (GvHD)
Spinal Cord Injuries
Cornea Repair
Cancers
Driving Forces
Limiting Factors
Technologies
Regulations
Market Acceptance
Clinical Efficiency

CHAPTER 11 COMPETITIVE LANDSCAPE

Mergers and Acquisitions
Strategic Alliances

CHAPTER 12 COMPANY PROFILES

ADDGENE
ALLELE BIOTECHNOLOGY AND PHARMACEUTICALS INC.
ALSTEM
APPLIED BIOLOGICAL MATERIALS INC. (ABM)
APPLIED STEMCELL INC. (ASC)
ATCC
AXOL BIOSCIENCE? LTD.
BIO-TECHNE
BLUEROCK THERAPEUTICS
BRISTOL-MYERS SQUIBB (IPIERIAN)
CELL SIGNALING TECHNOLOGY (CST)
CORNING INC.
CREATIVE BIOARRAY?
FATE THERAPEUTICS
FUJIFILM CELLULAR DYNAMICS INC. (FCDI)
GENECOPOEIA
GENTARGET INC.
ID PHARMA CO., LTD.
INVIVOGEN
LONZA GROUP LTD.
MEGAKARYON CORP.
MERCK KGaA
MTI-GLOBALSTEM, A PART OF THERMO FISHER SCIENTIFIC
NCARDIA
NEWCELLS BIOTECH
PEPROTECH
PLASTICELL LTD.
PROMEGA CORP.
PROMOCELL GMBH
QIAGEN N.V.
REPROCELL INC.
SCIENCELL RESEARCH LABORATORIES
STEMCELL TECHNOLOGIES?
SYSTEM BIOSCIENCES INC.
TAKARA BIO USA INC. (CLONTECH LABORATORIES)
THERMO FISHER SCIENTIFIC
VIACYTE INC.
WAISMAN BIOMANUFACTURING

CHAPTER 13 APPENDIX:
LIST OF ACRONYMS


LIST OF TABLES

Summary Table: Global Market for Induced Pluripotent Stem Cells, by Country/Region, Through 2026
Table 1: Pros and Cons Associated with the Use of iPSCs
Table 2: iPSCs Banks Worldwide, 2019
Table 3: Global Market for Induced Pluripotent Stem Cells, by Country/Region, Through 2026
Table 4: U.S. Market for Induced Pluripotent Stem Cells, by State, Through 2026
Table 5: European Market for Induced Pluripotent Stem Cells, by Country, Through 2026
Table 6: Asia-Pacific Market for Induced Pluripotent Stem Cells, by Country, Through 2026
Table 7: Global Market for the Generation of Induced Pluripotent Stem Cells, by Reprogramming Method, Through 2026
Table 8: Global Market for the Generation of Induced Pluripotent Stem Cells, by Method, Through 2026
Table 9: Global Market for Induced Pluripotent Stem Cell Products, by Application, Through 2026
Table 10: U.S. Market for Induced Pluripotent Stem Cell Products, by Application, Through 2026
Table 11: European Market for Induced Pluripotent Stem Cell Products, by Application, Through 2026
Table 12: Asia-Pacific Market for Induced Pluripotent Stem Cell Products, by Application, Through 2026
Table 13: Rest of the World Market for Induced Pluripotent Stem Cell Products, by Application, Through 2026
Table 14: Global Market for Induced Pluripotent Stem Cell-Derived Tissue Cells, by Type, Through 2026
Table 15: Global Market for Induced Pluripotent Stem Cell-Derived Cells, by Species, Through 2026
Table 16: Major Commercial Suppliers of Induced Pluripotent Stem Cells Products, by Country
Table 17: Major Commercial Manufacturers of Induced Pluripotent Stem Cells, by Country
Table 18: Global Market for Induced Pluripotent Stem Cell-Derived Cells, by Application, Through 2026
Table 19: Global Market for Induced Pluripotent Stem Cell-Related Products, by Product Function, Through 2026
Table 20: U.S. Market for Induced Pluripotent Stem Cell-Related Products, by Product Function, Through 2026
Table 21: European Market for Induced Pluripotent Stem Cell-Related Products, by Product Function, Through 2026
Table 22: Asia-Pacific Market for Induced Pluripotent Stem Cell-Related Products, by Product Function, Through 2026
Table 23: RoW Market for Induced Pluripotent Stem Cell-Related Products, by Product Function, Through 2026
Table 24: Global Market for Induced Pluripotent Stem Cells in Research and Clinical Uses, Through 2026
Table 25: Global Market for Induced Pluripotent Stem Cell-Related Products, by Function, Through 2026
Table 26: Major University and Institute Facilities for Induced Pluripotent Stem Cell Core, by Location/Country
Table 27: Major Companies Providing iPSC Contract Services, by State/Country
Table 28: Global Market for Induced Pluripotent Stem Cell Contract Services, by Country/Region, Through 2026
Table 29: Major Governmental Induced Pluripotent Stem Cells Research Funding and Share, by Country/Region, 2006-October 2019
Table 30: National Institutes of Health Induced Pluripotent Stem Cells Research Funding, 2006-October 2019
Table 31: California Institute of Regenerative Medicine Induced Pluripotent Stem Cells Funding, October 2019
Table 32: U.S. Patents on Induced Pluripotent Stem Cells
Table 33: Number and Share of Global Patents or Patent Applications on Induced Pluripotent Stem Cells, by Country, October 2019
Table 34: Distribution of Patents and Patent Applications on Induced Pluripotent Stem Cells, by Patent Office or Country, October 2019
Table 35: Main Inventors Listed on Global Patents or Patent Applications on Induced Pluripotent Stem Cells, October 2019
Table 36: Main Applicants Listed on Global Patents or Patent Applications on Induced Pluripotent Stem Cells, October 2019
Table 37: Global Patents and Patent Applications on Induced Pluripotent Stem Cells, by Year, 2008-October 2019
Table 38: U.S. Patents on Induced Pluripotent Stem Cells, 2009-October 2019
Table 39: Global Patents and Patent Applications Filed with the USPTO on Induced Pluripotent Stem Cells, by Assignee’s Country, October 2019
Table 40: U.S. Patents and Share on Induced Pluripotent Stem Cells, by U.S. State, October 2019
Table 41: Scientific Publications of Induced Pluripotent Stem Cells Research, 2006-October 2019
Table 42: Acronyms Used in the iPSCs Industry

LIST OF FIGURES

Summary Figure A: Global Market for Induced Pluripotent Stem Cells, by Country/Region, 2020-2026
Summary Figure B: Global Market Shares of Induced Pluripotent Stem Cells, by Country/Region, 2020
Figure 1: Global Market Shares of Induced Pluripotent Stem Cells, by Country/Region, 2020
Figure 2: U.S. Market Shares of Induced Pluripotent Stem Cells, by State, 2020
Figure 3: European Market Shares of Induced Pluripotent Stem Cells, by Country, 2020
Figure 4: Asia-Pacific Market Shares of Induced Pluripotent Stem Cell Products, by Country, 2020
Figure 5: Global Market Shares of the Generation of Induced Pluripotent Stem Cells, by Reprogramming Method, 2020
Figure 6: Global Market Shares of the Generation of Induced Pluripotent Stem Cells, by Method, 2020
Figure 7: Global Market Shares of Induced Pluripotent Stem Cell Products, by Application, 2020
Figure 8: U.S. Market Shares of Induced Pluripotent Stem Cell Products, by Application, 2020
Figure 9: European Market Shares of Induced Pluripotent Stem Cell Products, by Application, 2020
Figure 10: Asia-Pacific Market Shares of Induced Pluripotent Stem Cell Products, by Application, 2020
Figure 11: Rest of the World Market Shares of Induced Pluripotent Stem Cell Products, by Application, 2020
Figure 12: Global Market Shares of Induced Pluripotent Stem Cell-Derived Tissue Cells, by Type, 2020
Figure 13: Global Market Shares of Induced Pluripotent Stem Cell-Derived Cells, by Application, 2020
Figure 14: Global Market Shares of Induced Pluripotent Stem Cell-Related Products, by Product Function, 2020
Figure 15: U.S. Market Shares of Induced Pluripotent Stem Cell-Related Products, by Product Function, 2020
Figure 16: European Market Shares of Induced Pluripotent Stem Cell-Related Products, by Product Function, 2020
Figure 17: Asia-Pacific Market Shares of Induced Pluripotent Stem Cell-Related Products, by Product Function, 2020
Figure 18: RoW Market Shares of Induced Pluripotent Stem Cell-Related Products, by Product Function, 2020
Figure 19: Global Market Shares of Induced Pluripotent Stem Cells in Research and Clinical Uses, 2020
Figure 20: Global Market Shares of Induced Pluripotent Stem Cell-Related Products, by Function, 2020
Figure 21: Global Market Shares of Induced Pluripotent Stem Cell Contract Services, by Country/Region, 2020
Figure 22: National Institutes of Health Funding Amounts for Induced Pluripotent Stem Cells Research, 2006-October 2019
Figure 23: Number of Global Patents and Patent Applications on Induced Pluripotent Stem Cells, 2008-October 2019
Figure 24: Number of U.S. Patents on Induced Pluripotent Stem Cells, 2009-October 2019
Figure 25: Scientific Publications of Induced Pluripotent Stem Cell Research, 2006-October 2019
Figure 26: Bio-Techne: Annual Revenue, 2018-2020
Figure 27: Bio-Techne: Revenue Share, by Country/Region, 2020
Figure 28: Bio-Techne: Revenue Share, by Business Segment, 2020
Figure 29: Bristol-Myers Squibb: Annual Revenue, 2018-2020
Figure 30: Bristol-Myers Squibb: Revenue Share, by Country/Region, 2020
Figure 31: Corning Inc.: Annual Revenue, 2018-2020
Figure 32: Corning Inc.: Revenue Share, by Business Segment, 2020
Figure 33: Thermo Fisher Scientific: Annual Revenue, 2019 and 2020
Figure 34: Thermo Fisher Scientific: Revenue Share, by Segment, 2020


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