Vaccines 2012 World Market Analysis, Key Players, Trends, Pediatric and Adult Segments

September 2012 | 249 pages | ID: V3DE6F23C7AEN
Kalorama Information

Abstracts

This report examines the market for vaccines used in humans to previous various types of disease. It covers only commercialized vaccines and developmental vaccines for diseases that are already vaccine-preventable; it does not cover emerging vaccines for diseases that are not currently vaccine-preventable, such as Alzheimer’s disease, diabetes, Ebola infection, Epstein-Barr virus (EBV) infection, ETEC infection, heart attach, Helicobacter pylori infection, multiple sclerosis, Parkinson’s disease, West Nile virus (WNV) infection, etc.; vaccines that address these and other not-yet-vaccine-preventable conditions are discussed in Kalorama’s new report, “What's Next in Vaccines.”

The vaccine industry has seen changes in the past year, and these are covered in this report Vaccines 2012: World Market Analysis, Key Players, and Critical Trends in a Fast-Changing Industry. The high growth rates and successful launch of several products recently have kept interest in the global vaccine market high. The global market for vaccines experienced strong growth through 2011 and this is expected to continue through the forecast period. Growth is being fueled by new product introductions and rising usage in all regions.

Included in this report are current market size and forecast for the following vaccines:

Pediatric Vaccines:

• Combinations
• Hepatitis
• HIB
• MMR
• Pneumococcal
• Poliovirus
• Varicella
• Other Pediatric

Adult Vaccines:

• Cervical Cancer
• Hepatitis
• Influenza
• Pneumococcal
• Travel; DT; Misc.

Kalorama has expanded the global perspective of this report in this edition, including estimates of vaccine sales (pediatric and adult segments) in the following regions:

• U.S.
• Rest of North Amer.
• South America
• Europe
• Japan
• India
• China
• Rest of World

Despite ongoing improvements in pediatric vaccination, it is estimated that at least two million children die each year from diseases that could have been prevented by already existing vaccines. This problem is most significant in low income countries, with the health disparity between rich and poor countries resulting in average life spans of about 77 and 52 years, respectively. In addition to this high death toll, millions more suffer disability and illness because they have not been immunized. Adult immunization is an important, but frequently overlooked, part of patient care. Vaccination programs typically focus on children, yet adults in industrialized countries are more likely to die as a result of vaccine-preventable diseases than are children.

Key issues in the global vaccine market today include product safety, refusal to immunize, supply shortages, the use of vaccines to prevent pandemics and address bioterrorism, and innovations in vaccine delivery systems.The following issues are discussed in this report.

• Vaccine Safety
• Refusal to Immunize
• Obesity
• Post-Licensure Surveillance
• The Future of Vaccine Safety
• Vaccine Shortages
• Preventing Pandemics
• Project Bioshield Act
• National Bio and Agro-Defense Facility
• DNA Vaccination
• Mucosal Delivery
• Intranasal Delivery
• Vaccine Patches
• Vaccine Chips and Microneedles
• Innovations in Vaccine Production
• Nanoparticle Systems
• Cloning

Vaccination protects not only individuals, but also entire communities from diseases spread by person-to-person transmission.For example, vaccination can prevent about 50% of deaths from pneumococcal disease and 80% of deaths from influenza-related complications in the elderly. Pharmacoeconomic studies have demonstrated the value of influenza and pneumococcal vaccines; however, immunization rates for these diseases continue to be low in the elderly populations. This report includes profiles of the key players in vaccines, including:

• AlphaVax, Inc.
• Bavarian Nordic A/S
• Baxter Healthcare
• Bharat Biotech
• Crucell /Johnson & Johnson
• Emergent biosolutions
• GlaxoSmithKline
• Medimmune
• Merck & Co. Inc
• Novartis
• Sanofi Pasteur
• Pfizer

Contents

CHAPTER ONE: EXECUTIVE SUMMARY

The Global Vaccine Industry
  Scope and Methodology
  Overview
  Pediatric Preventative Vaccines
  The Market
  Adult Preventative Vaccines
  The Market
  Total Market
  Issues and Trends

CHAPTER TWO: INTRODUCTION TO VACCINES

A Brief History: The Development of Vaccines
The Immune Response
Mechanism of Action
Types of Vaccines
  Attenuated (Weakened) Live Viruses
  Killed (Inactivated) Viruses
  Toxoid Vaccines
  Genetically Engineered/Modified Vaccines
  Vaccine Approval Process

CHAPTER THREE: PEDIATRIC PREVENTIVE VACCINES

Introduction
Childhood Immunization in the United States
  Childhood Immunization Rates
  Challenges to the Vaccine Delivery System
  The Effect of U.S. Healthcare Reform
  Recommended Childhood Immunization Schedule
  State Immunization Recommendations
  United Nations Initiatives
Pediatric Vaccine Products
  BCG
  Diphtheria, Tetanus, Pertussis, Hepatitis B and Polio
  Haemophilus Influenzae Type B
  Hepatitis A
  Measles, Mumps and Rubella
  Meningococcal Disease
  Pneumococcal Conjugate
  Rotavirus
  Varicella
Pediatric Vaccines in Development
Cost of Vaccines in the United States
The World Market for Pediatric Preventive Vaccines
  Total Market Size and Forecast
  Hepatitis Vaccine Market
  Haemophilus Influenzae Type B Vaccine Market
  Measles, Mumps and Rubella Vaccines
  Combination Vaccines Market
  Pneumococcal Vaccine
  Poliovirus Vaccine
  Varicella Vaccines
  Other Vaccines Market

CHAPTER FOUR: ADULT PREVENTIVE VACCINES

Introduction
Adult Vaccine-Preventable Diseases: Facts and Figures
Global Influenza Surveillance Program
  U.S. Surveillance
  
Recommendations for Adult Immunizations
  WHO International Health Regulations
Adult Vaccine Products
  Cervical Cancer
  Cholera
  Diphtheria-Tetanus
  Hepatitis
  Influenza
  Japanese Encephalitis
  Pneumococcal Disease
  Rabies
  Shingles
  Typhoid Fever
  Yellow Fever
Adult Vaccines in Development
The World Market for Adult Preventive Vaccines
  Total Market Size and Forecast
  Cervical Cancer Market
  Hepatitis Market
  1Influenza Vaccine Market
  Travel, DT, and Miscellaneous Vaccine Market

CHAPTER FIVE: VACCINES MARKET SUMMARY

Trends Driving the Vaccines Market
Market Size and Forecast
Vaccine Sales by Region
Vaccine Market Competitors
Pediatric Vaccines
Adult Vaccines

CHAPTER SIX: ISSUES AND TRENDS

Vaccine Safety
Refusal to Immunize
Obesity
Post-Licensure Surveillance
The Vaccine Injury Compensation Program
World Health Organization
Other Initiatives
The Future of Vaccine Safety
Vaccine Shortages
Preventing Shortages in the Developed Countries
Preventing Shortages in Developing Nations
Preventing Pandemics
U.S. National Vaccine Plan
Vaccines and Bioterrorism
Overview
Project Bioshield Act
National Bio and Agro-Defense Facility
Vaccine Treatment and Evaluation Units
Anthrax
Smallpox
DNA Vaccination
Innovations in Vaccine Delivery Systems
Mucosal Delivery
Intranasal Delivery
Vaccine Patches
Vaccine Chips and Microneedles
Innovations in Vaccine Production
Plants
Insects
Nanoparticle Systems
Cloning

CHAPTER SEVEN: COMPANY PROFILES

AlphaVax, Inc.
  History and Lines of Business
  Strategic Alliances
  Vaccine Products
  Financial Information
Bavarian Nordic A/S
  History and Lines of Business
  Strategic Alliances
  Vaccine Products
  Financial Information
Baxter Healthcare
  History and Lines of Business
  Strategic Alliances
  Vaccine Products
  Financial Information
Bharat Biotech
  History and Lines of Business
  Strategic Alliances
  Vaccine Products
  Financial Information
Crucell /Johnson & Johnson
  History and Lines of Business
  Strategic Alliances
  Vaccine Products
  Financial Information
Emergent biosolutions
  History and Lines of Business
  Strategic Alliances
  Vaccine Products
  Financial
GlaxoSmithKline
  History and Lines of Business
  Strategic Alliances
  Vaccine Products
  Financial Information
Medimmune
  History and Lines of Business
  Strategic Alliances
  Vaccine Products
  Financial Information
Merck & Co. Inc
  History and Lines of Business
  Strategic Alliances
  Vaccine Products
  Financial Information
Novartis
  History and Lines of Business
  Strategic Alliances
  Vaccine Products
  Financial Information
  History and Lines of Business
  Strategic Alliances
  Vaccine Products
  Financial Information
Sanofi Pasteur
  History and Lines of Business
  Strategic Alliances
  Vaccine Products
  Financial Information

APPENDIX: COMPANY DIRECTORY