Solvents: Market Research Report
Contents
1.INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONSStudy Reliability and Reporting Limitations
Disclaimers
Data Interpretation & Reporting Level
Quantitative Techniques & Analytics
Product Definitions and Scope of Study
2.INDUSTRY OVERVIEW
Market Potential
Regenerative Medicine in Bone and Joint Applications
US Corners a Lion’s Share
Regenerative Medicine - the Past, the Present, & the Future
Another Revolution in the Making?
Conventional Chemical Medicine Vs Regenerative Medicine
The Need for Regenerative Medicine
Regenerative Medicine Throws in Several New Therapies
What’s in Store?
Regenerative Medicine to Arrest Ageing
Thriving on an Aging World Population
Faster Healing Process
Regenerative Medicine to Overcome Donor Organs Shortage
Possible Scenarios
Stem Cell Research – Not Just Another Medical Advancement
Key Issues At Play
Growth Drivers
Trends & Issues
Biomaterials Sought After in Regenerative Medicine
Upbeat Market for Cell-based Tissue Engineering
Progenitor Cell Therapy to Witness No Holds Barred Growth
Players Embrace Automation in Production Facilities
Contract Manufacturing, a Growing Sector
Investors Wary of Funding Regenerative Medicine
Regenerative Medicine Field Lags Behind due to Segregated Focus
Challenges to Be Encountered by Tissue Engineering Companies
Activity in the Field of Regenerative Medicine
3.PRODUCT OVERVIEW
Regenerative Medicine Advances in Four Phases
Human Substances
Tissue Engineering
Therapeutic Cloning
Nanotechnology-Driven Biomaterials
Types of Regenerative Medicine
Type I – Regenerative Medicine
Human Proteins and Genes are Drugs in Regenerative Medicine
Type-2 Regenerative Medicine
Therapies Based on Human Cells and Tissues
Type-3 Regenerative Medicine
Based on Embryonic Stem Cells
The Opponents of the ESC Theory
Embryonic Stem Cells – Shortcomings
Type-4 Regenerative Medicine
Based on Novel Materials / Material Science Advancements
Overview of Major Regenerative Medicine Techniques
Natural Regenerative Proteins
Tissue Engineering Capable of Culturing Replacement Organs
All About Stem Cells
Adult Stem Cells
Adult Stem Cell Research Eludes Ethical Dispute
hESC – Highly Capable of Differentiating and Multiplying
Stem Cell Research in Development of Regenerative Medicine
Neural Stem Cell to Restore Memory Functioning
Pancreatic Islet Cells to Control Blood Sugar in Diabetics
Therapeutic Cloning to Cure Parkinson’s
4.REGULATORY ENVIRONMENT
Regulatory Norms Governing ES Cell Research
Milestones in the Human Embryonic Stem Cell Research: 2001
Legality of ES Cell Use in Major Developed Nations
5.TECHNOLOGICAL INNOVATIONS / BREAKTHROUGHS
Kensey Nash’s Medeor ECM Receives Approval from US FDA
Celling Technologies Unveils Res-Q Device
Kinetic Wins FDA Approval for LifeCell Tissue Matrix
6.TECHNOLOGICAL INNOVATIONS IN RECENT PAST – A PERSPECTIVE BUILDER
Celprogen Launches 11 Cancer Stem Cells
Biovest International Launches AutovaxID™
Stelic Institute Announces New Treatment Method for Acute Liver Failure
TissueGene Initiates Phase 1 Clinical Trials for TG-C
ISTO Announces FDA’s IND Approval for Neocartilage Graft
Cook Biotech Introduces Surgisis® AFP™ Anal Fistula Plug
Korean Scientists Make a Major Breakthrough in Stem Cell Lines
Japanese Researchers Regenerate Jaw Bone
Geron Researchers Differentiate Hepatocytes from hESCs
Geron Demonstrates Potential of hESCs in Treatment of Parkinson’s disease
Geron Researches Cardiomyocytes for Heart Disease
Endovasc Announces New Findings at Texas Heart Institute Research
Geron and Celera Genomics Complete Characterization of Active Genes in hESCs
Rockefeller University Develops Solution for Maintaining Plupotency in hESCs
7.RECENT INDUSTRY ACTIVITY
Power3 Medical Inks Definitive Agreement to Acquire StemTroniX
Healthpoint Acquires CYZACTTM and ICX-SKN Technologies from Intercytex
Stem Cell Therapy International Merges with Histostem
TiGenix Acquires Orthomimetics
Integra Inks Licensing Deal with Organogenesis
DePuy Spine Collaborates with ATRM
Epistem Enters into Partnership with Novartis
Athersys Inks Agreement with Pfizer
Beike Biotechnology Signs Investment Agreement with Biomaster
Fujifilm Establishes New Drug Discovery Labs
KCI Acquires LifeCell
Organogenesis Takes Over NanoMatrix
Cytori and Green Hospital Supply Ink Strategic Equity Deal
Sigma-Aldrich Signs Agreement with AlphaGenix
RNL Bio Establishes Research Unit at Newcastle University
Pfizer Establishes New Regenerative Medicine Research Unit
Tengion Begins Third Phase II Clinical Trial of Neo-Bladder Augment™
8.CORPORATE ACTIVITY IN RECENT PAST – A PERSPECTIVE BUILDER
Integra Life Sciences Acquires IsoTis, Inc.
Geron Increases Stake in TA Therapeutics
Organogenesis Signs MoU with NTEC
BioTime Establishes New Stem Cell Division
NovaThera and Gamida Join Hands for Developing Cell Therapeutics for Lung Regeneration
Tigenix Teams Up With Fidea to Develop Biological Joint Implants
Scotland Plans to Build Center for Regenerative Medicine in Edinburgh
9.FOCUS ON SELECT GLOBAL PLAYERS
BioVest International, Inc. (US)
Curis, Inc. (US)
Cytori Therapeutics, Inc. (US)
DeveloGen AG (Germany)
Forticell Bioscience, Inc. (US)
Geron Corporation (US)
Integra Orthobiologics (US)
LifeCell Corporation (US)
Osiris Therapeutics, Inc. (US)
Tengion (US)
Tepha Inc. (US)
TiGenix N.V. (Belgium)
10.GLOBAL MARKET PERSPECTIVE
Table 1: World Recent Past, Current & Future Market Analysis for Regenerative Medicine Products for Bone and Joint Applications by Geographic Region – US, Japan and Europe Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2015 (includes corresponding Graph/Chart)
Table 2: World Historic Review for Regenerative Medicine Products for Bone and Joint Applications by Geographic Region – US, Japan, and Europe Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)
Table 3: World 11-Year Perspective for Regenerative Medicine Products for Bone and Joint Applications by Geographic Region – Percentage Breakdown of Dollar Sales for US, Japan and Europe for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart)
11.THE UNITED STATES
A. Market Analysis
Market Potential
Regenerative Medicine in Bone and Joint Applications
Table 4: US Market for Regenerative Medicine Products for Bone and Joint Applications (2007, 2010 & 2013): Percentage Breakdown of Value Sales for Bone Replacement Grafting, Bone Growth Stimulators, and Tissue Engineering Cartilage (includes corresponding Graph/Chart)
Regenerative Therapy – Best Fit for Joint Problems
Millions of American Patients Put their Hope in Stem Cell Research
Table 5: Prevalence of Various Diseases in the US (includes corresponding Graph/Chart)
US Witnesses Mixed Response for Government Support for hESC Research
CBI’s Human Tissue Products for Treating Liver Failure and Diabetes
Market for Liver and Pancreas Transplantation
Implantable Regenerative Products Take Over Sports Medicine
Key Players
Other Dominating Regional Players
B. Market Analytics
Table 6: US Recent Past, Current & Future Analysis for Regenerative Medicine Products for Bone and Joint Applications – Annual Sales Figures in US$ Million for Years 2009 through 2015 (includes corresponding Graph/Chart)
Table 7: US Historic Review for Regenerative Medicine Products for Bone and Joint Applications Market with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)
12.JAPAN
A. Market Analysis
Market Potential
Research Activity in Regenerative Medicine Field
More Companies Eye the Regenerative Medicine Potential
Competition Heats up Behind Closed Doors
Japanese Firms Need to Catch Up with US and European Competitors
Science Ministry Rolls Out Regenerative Medicine Project
Regenerative Medicine Exempted from Ban on Human Cloning
B. Market Analytics
Table 8: Japanese Recent Past, Current & Future Analysis for Regenerative Medicine Products for Bone and Joint Applications with Annual Sales Figures in US$ Million for Years 2009 through 2015 (includes corresponding Graph/Chart)
Table 9: Japanese Historic Review for Regenerative Medicine Products for Bone and Joint Applications with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)
13.EUROPE
A. Market Analysis
Oral Tissue Regeneration
Table 10: European Oral Tissue Regeneration Market (2009): Percentage Breakdown of Value Sales for Bone Graft Material, Membranes, and Tissue Regeneration (includes corresponding Graph/Chart)
Regional Overview
Germany
Key Players
United Kingdom
Belgium
Select Player
B. Market Analytics
Table 11: European Recent Past, Current & Future Analysis for Regenerative Medicine Products for Bone and Joint Applications with Annual Sales Figures in US$ Million for Years 2009 through 2015 (includes corresponding Graph/Chart)
Table 12: European Historic Review for Regenerative Medicine Products for Bone and Joint Applications Market with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)
14.REVIEW OF REGENERATIVE MEDICINE IN OTHER GEOGRAPHIC MARKETS
14A.CANADA
University of Toronto – Spearheading Regenerative Medicine Research
14B.ASIA-PACIFIC
China
Substantial Government Support
India
CSIR- Leading the way in Regenerative Medicine Research
High Growth Opportunities
Australia
Key Player
Stem Cell Sciences
South Korea
Malaysia
Singapore
14C.REST OF WORLD
Argentina
Israel
Select Major Players
Colbar R&D Ltd.
ProChon Biotech Ltd.
South Africa
Competition
Total Companies Profiled: 106 (including Divisions/Subsidiaries - 111)
Region/CountryPlayers
The United States60
Canada
Japan
Europe
Germany
The United Kingdom
Italy
Rest of Europe
Asia-Pacific (Excluding Japan)
Latin America
Africa
Middle-East
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