The Stem Cell Market Outlook

Date: June 22, 2011
Pages: 113
Price:
US$ 3,835.00
Publisher: Business Insights
Report type: Strategic Report
Delivery: E-mail Delivery (PDF)
ID: S9C3C217D29EN
Leaflet:

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The Stem Cell Market Outlook
Introduction

This report covers the commercialization of stem cells (primarily derived from adult tissues) which are transplanted into patients to improve the function of diseased/damaged tissues/organs. Six indications are covered in detail. Sales forecasts are estimated in the US and five major European markets (5EU), which include France, Germany, Italy, Spain and the UK.

Features and benefits
  • Identify potential growth markets with sales forecasts by indication and expected timing of market entry.
  • Compare the different business models for stem cell therapies.
  • Evaluate which novel products offer the greatest potential clinical advances over the next several years and why.
  • Assess potential clinical advances and how they address current unmet needs.
  • Understand the drivers and resistors of the stem cell market.

Highlights

Six indications were prioritized based on likely commercial potential and adoption into clinical practice: acute myocardial infarction, heart failure, critical limb ischemia, amyotrophic lateral sclerosis, spinal cord injury and ischemic stroke.

Companies are developing first generation therapies primarily based on ex vivo expanded allogeneic or autologous bone marrow derived stem cells. Recently, a second generation of products has entered clinical development, which may build on the efficacy of first generation products.

The greatest potential revenues are forecast in diseases or conditions with significant mortality or morbidity and limited treatment options, for which autologous bone marrow mononuclear cells (BMMNCs) may not be applicable or ineffective and lower patient numbers can be offset by higher prices.

Your key questions answered
  • What is the future commercial value of stem cell therapies?
  • Which products are likely to be reimbursed and what price could be charged?
  • Which indications offer the greatest sales potential?
  • What are the competitive risks to commercialization and how can companies develop profitable business models?
  • Which companies are attractive for investment?
EXECUTIVE SUMMARY

Market overview
Acute myocardial infarction
Heart failure
Critical limb ischemia
Central nervous system disorders
Other indications
Business models and market forecasts

ABOUT THE AUTHOR

Disclaimer

MARKET OVERVIEW

Summary
Introduction
Market definition
Stem cell types
  Adult stem cells
  Embryonic stem cells
Clinical landscape
Regulation
  European Union
  Japan
  India
  China
Industry overview
  Market value
  Licensing and merger activity
Conclusions

ACUTE MYOCARDIAL INFACTION

Summary
Introduction
Clinical review
Pipeline analysis
  Allogeneic products
  Cell processing devices
Market potential
  Calculation of addressable population
  Market adoption scenario
Future outlook

HEART FAILURE

Summary
Introduction
Clinical review
  Ongoing trials using BMMNCs or MSCs
  Other stem cells types
  Mechanism of action
Pipeline analysis
  Autologous products
  Allogeneic products
Market size
Future outlook

CRITICAL LIMB ISCHEMIA

Summary
Introduction
Clinical review
Pipeline analysis
  Autologous products
  Allogeneic products
  Cell processing devices
Market size
Future outlook

CENTRAL NERVOUS SYSTEM DISORDERS

Summary
Introduction
Amyotrophic lateral sclerosis
Spinal cord injury
Ischemic stroke
Future outlook

OTHER INDICATIONS

Summary
Introduction
Graft versus host disease
Solid organ transplants
Diabetes mellitus
Chronic obstructive pulmonary disease
Inflammatory bowel disease
Acute kidney injury
Alzheimer's disease
Parkinson's disease
Multiple sclerosis

BUSINESS MODELS AND MARKET FORECASTS

Summary
Introduction
Key success factors
  Acute versus elective conditions
  Regulatory considerations
  Stem cell quality
  Manufacturing process
  Clinical trial design
Business models
  Allogeneic product models
  Autologous product models
  Device based models
Pricing and reimbursement
Sales forecasts to 2025
Future outlook

APPENDIX

Scope
Methodology
Abbreviations
References
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