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World Market for Anti-Infectives (Antifungals, Antibacterials and Antivirals)

February 2012 | 220 pages | ID: O8D9435FF43EN
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This Kalorama Information report – The World Market for Anti-Infectives - focuses on three key segments of treatment:
  • Antifungals (Allylamines, Azoles, Polyene Macrolides, Other Antifungals)
  • Antibacterials (Aminoglycosides, Carbapenems, Cephalosporins, Macrolides, Penicillins, Quinolones, Sulfonamides, Tetracyclines, Others)
  • Antivirals (Nucleoside Analogs, Transcriptase Inhibitors, DNA Polymerase Inhibitors, Protease Inhibitors, Other Antivirals)
The report covers both currently marketed and late stage development products. Revenues for each segment were generated using dollar and unit sales for each product.

A novel approach of this report is it provides revenue by product type but also the 'market' for treatments by type of infection, enabling the marketer to research the best markets where a variety of products may be implemented. The report includes statistical information for infections by type worldwide, with special emphasis on the U.S. and Europe. The market segments provide an overview, description of products on the market, description of products in development, market estimates and forecasts, and competitive analysis of leading providers.

The area of anti-infectives represents an exciting frontier for development of potential life-saving products. However, there are a number of issues and trends that have a direct influence on this market and the manufacturer’s ability to successfully operate in the market. The issues and trends affecting this market include:
  • Drug Resistance
  • HIV Trends, Cost, and Access to Drug Therapy
  • Other Immunocompromised Population Issues
  • Alliances and Partnerships
  • New Developments
  • Rx-to-OTC Switches
CHAPTER ONE: EXECUTIVE SUMMARY

Introduction

Scope and Methodology

Total Size and Growth of the Market

Issues and Trends Affecting Market

Leading Competitors

CHAPTER TWO: INTRODUCTION AND INDUSTRY TRENDS

Overview

Introduction to Pathogens

Demographics of the World

Life Expectancy

Infections and Drug Resistance

Causes of Drug Resistance

Drug Resistance in Select Populations

Measures for Reducing Resistance

HIV Trends

Manufacturer and Marketer Trends

Trends in Partnerships and Alliances

Developers Trends

Aradigm

ARD-3100

Phase II

Cystic fibrosis

ARD-3150

Phase II

Bronchiectasis

ARD-1100

Preclinical

Inhalation anthrax

Trends in Rx-to-OTC Switches

CHAPTER THREE: ANTIFUNGAL DRUGS

Overview

Types of Fungal Infections

Superficial

Systemic

General Fungal Infection Statistics

Fungal Infection Risk

Description of Antifungal Products

Systemic Antifungals

Topical Antifungals

Market Overview

Total Market Size and Forecast

Antifungal Market by Product Type

Antifungal Market by Geographical Region

Market Analysis by Treated Condition

Competitive Analysis

Leading Products

CHAPTER FOUR: ANTIBACTERIAL DRUGS

Overview

Classification of Antibacterial Organisms

Antimicrobial Spectrum

Bacterial Resistance

Principles of Anti-bacterial Therapy

Combination Therapy and Prophylactic Use

Bacterial Infection Statistics

Bacterial Infection Risk

Classifications of Antibacterial Products

Aminoglycosides

Carbapenems

Cephalosporins

Macrolides

Penicillins

Quinolones

Sulfonamides

Tetracyclines

Market Overview

Total Market Size and Forecast

Antibacterial Market by Product Type

Antibacterial Market by Geographical Region

Market Analysis by Treated Condition

Competitive Analysis

Leading Products

CHAPTER FIVE: ANTIVIRAL DRUGS

Overview: Introduction to Viruses

Examples of Pathogenic Viruses

Virus Function and Life History

Replication in DNA Viruses

Replication of RNA Viruses

Replication in Retroviruses

Host Defenses Against Viruses 8

Viral Ploys to Invade Host Cells and Circumvent Host Responses

Invasion of Host Cells

Subversion of the Immune Response

Avoidance of Immune Detection and Attack by Killer Cells

HIV and AIDS

Viral Infection Statistics

Description of Antivirals Products

Nucleoside Analogs, Transcriptase Inhibitors and DNA Polymerase Inhibitors

Protease Inhibitors

Other Antivirals

Market Overview

Total Market Size and Forecast

Antiviral Market by Product Type

Antiviral Market by Geographical Region

Market Analysis by Treated Condition

Competitive Analysis

Leading Products

CHAPTER SIX: MARKET SUMMARY

Market by Product Segment (Antifungals, Antibacterials, Antivirals)

CHAPTER SEVEN: CORPORATE PROFILES

Introduction

Abbott Laboratories

Astellas

AstraZeneca

Bayer Healthcare Pharmaceuticals (Bayer Schering Pharma)

Bristol-Myers Squibb

Cubist

Daiichi Sankyo

Gilead Sciences

GlaxoSmithKline

Johnson & Johnson

Merck

Novartis

Pfizer

Roche

APPENDIX: COMPANY DIRECTORY

TABLE OF EXHIBITS

CHAPTER ONE: EXECUTIVE SUMMARY

Table 1-1: The Global Market for Anti-Infectives by Product Segment, 2007-2015

Figure 1-1: The Global Market for Anti-Infectives by Product Segment, 2011

Figure 1-2: World Market for Anti-Infectives Estimated Market Share of Leading Suppliers, 2011

CHAPTER TWO: INTRODUCTION AND INDUSTRY TRENDS

Table 2-1: World Population by Selected Geographical Region, 2010 - 2050

Table 2-2: Average Life Expectancy in Years by Country 1980, 2004 and 2009

Figure 2-2: Average Life Expectancy in Years by Country 1980 and 2009

Table 2-3: Worldwide HIV/AIDS Infections

Table 2-4: Women Living with HIV/AIDS, by Region 2001 to 2009, Number

Table 2-5: Antiretroviral Access for HIV Infected Individuals in Low- and Middle-Income Countries, 2009 based on 2010 WHO Guidelines

Table 2-6: Antiretroviral Access for HIV Infected Individuals in Low- and Middle-Income Countries, by Selected Countries, 2009 based on 2010 WHO Guidelines

Table 2-7: Anti-Infective Drugs in Development by Developer

Table 2-8: Anti-infectives Ingredients Transferred from Rx-to-OTC Status

Figure 2-3: Anti-infectives Ingredients Transferred from Rx-to-OTC by Year

CHAPTER THREE: ANTIFUNGAL DRUGS

Table 3-1: Incidence of Infections by Type, 2010

Figure 3-1: Incidence of Infections by Type, 2010

Table 3-2: World Population at Risk for Fungal Infections, Secondary to Chronic Diseases by Selected Geographical Region, 2010

Figure 3-2: World Population at Risk for Fungal Infections, Secondary to Chronic Diseases by Selected Geographical Region, 2010

Table 3-3: Treatment Options for Fungal Infections , (Type, Brand, and Manufacturer)

Table 3-4: The World Market for Antifungal Drugs 2007-2015

Figure 3-3: The World Market for Antifungal Drugs 2007-2015

Table 3-5: Antifungal Drug Market by Type 2007-2015 , (Allylamines, Azoles, Polyene Macrolides, Other Antifungals)

Figure 3-4: The World Market for Antifungal Drugs Revenues by Type 2007-2015 , (Allylamines, Azoles, Polyene Macrolides, Other Antifungals)

Figure 3-5: The World Market for Antifungal Drugs Revenues by Type 2011 and 2015 , (Allylamines, Azoles, Polyene Macrolides, Other Antifungals)

Table 3-6: The World Market for Antifungal Drugs Estimated Products Sales by Geographic Region 2007-2015

Figure 3-6: The World Market for Antifungal Drugs Estimated Product Sales by Geographic Region 2007-2015

Table 3-7: World Antifungal Market Estimated Products Sales by Infection Type , (Candida Infections, Seborrheic Dermatitis, Onychomycosis, Other Infections)

Figure 3-7: World Antifungal Market Estimated Distribution of Products Sales by Infection Type, 2011 Candida Infections, Seborrheic Dermatitis, Onychomycosis, Other Infections)

Table 3-8: World Market for Antifungal Drugs Estimated Revenues and Market Share of Leading Suppliers 2007-2011

Figure 3-8: World Market for Antifungal Drugs Estimated Revenues of Leading Suppliers, 5-year Comparison 2007-2011

Figure 3-9: World Market for Antifungal Drugs Estimated Market Share of Leading Suppliers, 2011

Table 3-9: World Market for Antifungal Drugs Estimated Sales of Select Products 2007-2011

Figure 3-10: World Market for Antifungal Drugs Estimated Sales of Select Products 2007-2011

CHAPTER FOUR: ANTIBACTERIAL DRUGS

Table 4-1: Antibiotics with Difficult Penetration

Table 4-2: Estimated World and U.S. Incidence of Bacterial Infections, 2010

Figure 4-1: Estimated World and U.S. Incidence of Bacterial Infections

Table 4-3: World Population at Risk for Serious Bacterial Infections, Secondary to Chronic Diseases by Selected Geographical Region, 2010

Figure 4-2: World Population at Risk for Serious Bacterial Infections, Secondary to Chronic Diseases by Selected Geographical Region, 2010

Table 4-4: Treatment Options for Bacterial Infections , (Type, Brand, and Manufacturer)

Table 4-5: The World Market for Antibacterial Drugs 2007-2015

Figure 4-3: The World Market for Antibacterial Drugs 2007-2015

Table 4-6: Antibacterial Drug Market by Type 2007-2015

Figure 4-4: The World Market for Antibacterial Drugs Revenues by Type, 2007-2015 , (Aminoglycosides, Carbapenems, Cephalosporins, Macrolides, Penicillins, Quinolones, Sulfonamides, Tetracyclines, Others)

Figure 4-5: The World Market for Antibacterial Drugs Revenues by Type 2011 and 2015 , (Aminoglycosides, Carbapenems, Cephalosporins, Macrolides, Penicillins, Quinolones, Sulfonamides, Tetracyclines, Others)

Table 4-7: The World Market for Antibacterial Drugs Estimated Products Sales by Geographic Region 2007-2015

Figure 4-6: The World Market for Antibacterial Drugs Estimated Product Sales by Geographic Region 2007-2015

Table 4-8: World Antibacterial Market Estimated Products Sales by Infection Type , (Upper and Lower Respiratory Tract Infections, Ear, Sinus Infections, Skin & Skin Structure Infections Gynecological Infections; Sexually Transmitted Infections, Urinary Tract Infections, Abdominal Infections, Other Infections)

Figure 4-7: World Antibacterial Market Estimated Distribution of Products Sales by Infection Type, 2011 , (Upper and Lower Respiratory Tract Infections, Ear, Sinus Infections, Skin & Skin Structure Infections Gynecological Infections; Sexually Transmitted Infections, Urinary Tract Infections, Abdominal Infections, Other Infections)

Table 4-9: World Market for Antibacterial Drugs Estimated Revenues and Market Share of Leading Suppliers 2007-2011

Figure 4-8: World Market for Antibacterial Drugs Estimated Revenues of Leading Suppliers 2007-2011

Figure 4-9: World Market for Antibacterial Drugs Estimated Market Share of Leading Suppliers, 2011

Table 4-10: World Market for Antibacterial Drugs Estimated Sales of Select Products 2007-2011

CHAPTER FIVE: ANTIVIRAL DRUGS

Table 5-1: Host Cell Receptors

Table 5-2: Estimated World and U.S. Incidence of Viral Infections, 2010

Figure 5-1: Estimated World and U.S. Incidence of Leading Viral Infections

Table 5-3: Treatment Options for Viral Infections , (Type, Brand, and Manufacturer)

Table 5-4: The World Market for Antiviral Drugs 2007-2015

Figure 5-2: The World Market for Antiviral Drugs 2007-2015

Table 5-5: Antiviral Drug Market by Type 2007-2015

Figure 5-3: The World Market for Antiviral Drugs Revenues by Type , (Nucleoside Analogs, Transcriptase Inhibitors, DNA Polymerase Inhibitors, Protease Inhibitors, Other Antivirals) 2007-2015

Figure 5-4: The World Market for Antiviral Drugs Revenues by Type , (Nucleoside Analogs, Transcriptase Inhibitors, DNA Polymerase Inhibitors, Protease Inhibitors, Other Antivirals) 2011 and 2015

Table 5-6: The World Market for Antiviral Drugs Estimated Products Sales by Geographic Region 2007-2015

Figure 5-5: The World Market for Antiviral Drugs Estimated Product Sales by Geographic Region 2007-2015

Table 5-7: World Antiviral Market Estimated Products Sales by Infection Type (HIV, Hepatitis, Other Infections, Total)

Figure 5-6: World Antiviral Market Estimated Distribution of Products Sales by Infection Type, 2011 (HIV, Hepatitis, Other Infections, Total)

Table 5-8: World Market for Antiviral Drugs Estimated Revenues and Market Share of Leading Suppliers 2006-2009

Figure 5-7: World Market for Antiviral Drugs Estimated Revenues of Leading Suppliers 2007-2011

Figure 5-8: World Market for Antiviral Drugs Estimated Market Share of Leading Suppliers, 2011

Table 5-9: World Market for Antiviral Drugs Estimated Sales of Top Products 2007-2011

Figure 5-9: World Market for Antiviral Drugs Estimated Sales of Top Products 2007-2011

CHAPTER SIX: MARKET SUMMARY

Table 6-1: The Global Market for Anti-Infectives by Product Segment, 2007-2015

Figure 6-1: The World Market for Anti-Infective Drugs 2007-2015

Figure 6-2: The Global Market for Anti-Infectives by Product Segment, 2011

Figure 6-3: The Global Market for Anti-Infectives by Product Segment, 2015



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