DNA Sequencing In Drug Discovery: Market outlook for applications, tools and services, and 40 company profiles

Date: January 22, 2010
Pages: 179
Price:
US$ 3,835.00
Publisher: Business Insights
Report type: Strategic Report
Delivery: E-mail Delivery (PDF)
ID: D9E95F09E9CEN
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DNA Sequencing In Drug Discovery: Market outlook for applications, tools and services, and 40 company profiles
The advent of DNA sequencing technology has had a vast impact on the field of drug development. It has played a key role in the success of the Human Genome Project which has made it an essential tool for genetic analysis. Advanced technological developments in microarrays, bioinformatics and similar tools have increased the Scope of applications and services.

This report covers regional markets, products and services while evaluating them over the next five years, and profiles almost 40 companies involved in the DNA sequencing market.

Key Features of this report
  • It analyzes the market data ( revenues ) of DNA sequencing tools and services in North America, Europe, Asia and rest of the world that includes Middle East, Africa, Russia, Latin America and Australia.
  • Key market drivers and restraints for the parent segments and evaluation of respective sub segments with respect to market dynamics.
  • Covers microarray, DNA sequencing kits, chromatography, mass spectrometry, DNA amplification and many others within the tools market along with their sub segments. The services market includes high throughput sequencing , shot gun sequencing , re-sequencing, sample process and primer walking, single pass analysis and bacterial identification.

Scope of this report
  • Understand the emerging technologies and the growth associated for evaluation of potential of the type of products and services.
  • Understanding the product developments on which companies are focusing to evaluate new technological trends.
  • For evaluation of growth prospective for DNA sequencing applications and determining lucrative markets.

Key Market Issues
  • Funding from public institutes is encouraging market players to focus on the development of the DNA sequencing technology.
  • The withdrawal of certain drugs from the market due to their lack of efficacy among the worldwide patient population has created a need to address variations in diseases and drug responses on an individual basis.
  • Next generation sequencing may hinder the growth of the market for first-generation DNA sequencing technology especially in the drug discovery and development sector.

Key findings from this report
  • The DNA sequencing market growth is highest in the Asian and North American region, with Europe having the second largest market.
  • North America constitutes the major market share with next-generation sequencing attracting the new participants in the region.
  • The existing market participants are strategically positioning their DNA sequencing technologies by differentiating the specificity of the type of their tools and services.
  • Agilent Technologies, CLC Bio, and Life Technologies Corporation are some of the major DNA sequencing companies engaged in collaborative partnerships in the past couple of years.

Key questions answered
  • What are the important DNA sequencing markets and their growth over the period 2009-14?
  • What are the major technologies and services that have emerged in different areas such as microarray, PCR, re-sequencing, high throughput sequencing?
  • In which areas are the companies focusing while forming strategic alliances with other market players?
  • What is the current potential of DNA sequencing applications with respect to drug development and discovery?
DNA Sequencing in Drug Discovery
Executive summary
Market overview
Market dynamics
Global DNA sequencing tools & services market
Company profiles

CHAPTER 1 MARKET OVERVIEW

Summary
Evolution of DNA sequencing
DNA sequencing and drug discovery
Defining the market
Need for more reliable and compatible tools
High throughput and next-generation sequencing – attractive growth factors
DNA sequencing tools dominate the market
Protecting DNA sequencing technology
Applications of DNA sequencing
Drug development
Clinical trials
Whole genome testing
Toxicology prediction
Identification of drug resistance
Drug discovery

CHAPTER 2 MARKET DYNAMICS

Summary
Introduction
Regional markets
North America
Europe
Asia
RoW
Competitive landscape
Recent agreements and collaborations
Recent launches
Market drivers
Funding from public institutes
NGS technologies
Patient profiling for genetic disorders
Development of personalized medicine
High productivity rates
Market restraints
Shift in sequencing market trends
Introduction of NGS technologies

CHAPTER 3 GLOBAL DNA SEQUENCING TOOLS & SERVICES MARKET

Summary
DNA sequencing tools
Microarray
Biochip microarray
Gel array
Array design kit
Low and high density microarrays
Bioinformatics
Electrophoresis
Gel electrophoresis
Capillary electrophoresis
DNA sequencing kits
Consumables, chemicals, reagents and probes
DNA polymerase
Primers
Automated DNA sequencers
Chromatography
DNA amplification (PCR)
Mass spectrometry
Microscopy-based techniques
Electron microscopy
Atomic force microscopy
Microfluidics-enabled workstations
Barcode readers for DNA sample presentation
Computational chemistry and biology modeling
Spotters/arrayers
Centrifuge
Scanners
Thermal cyclers
Charge-coupled devices (CCDs)
Plates, strips and columns
DNA sequencing services
High throughput sequencing
Shotgun sequencing
Re-sequencing
Sample process and primer walking
Single pass analysis
Bacterial identification
Market drivers
Microarray technology is a powerful tool for high throughput screening
Increasing applications of microarrays
Increasing applications of bioinformatics in R&D
Technological breakthroughs generate need for efficient DNA sequencing
Genomics and drug discovery applications of automated sequencers
Diagnostic applications of automated sequencers
Applications in comparative research projects of automated sequencers
Developments in PCR technology
PCR is a reliable tool for multiple applications
Government initiative for funding
Market restraints
Limited scope of microarrays for pathogen enumeration
Time loss due to large number of laboratory specific variations for microarrays
Low cost next-generation technologies hinder growth of microarrays
Incompatibility issues of current bioinformatics tools
High cost of modifying supporting products
High cost and reliability issues of PCR technology

CHAPTER 4 COMPANY PROFILES

Summary
454 LIFE SCIENCES
  Company overview
  Products and services
  Company strategy
  Other events
Affymetrix
  Company overview
  Product and services
  Company strategy
Agilent Technologies
  Company overview
  Products and services
  Company strategy
Beckman Coulter, Inc
  Company overview
  Products and services
  Company strategy
Bio-Rad Laboratories
  Company overview
  Products and services
  Company strategy
Caliper Life Sciences
  Company overview
  Products and services
  Company strategy
CapitalBio Corp.
  Company overview
  Products and services
  Company strategy
CombiMatrix Corp.
  Company overview
  Products and services
  Company strategy
Commonwealth Biotechnologies, Inc
  Company overview
  Products and services
  Company strategy
Complete Genomics, Inc
  Company overview
  Products and services
  Company strategy
DNA Vision
  Company overview
  Products and services
  Company strategy
Enzo Biochem, Inc
  Company overview
  Products and services
  Company strategy
EPICENTRE Biotechnologies
  Company overview
  Products and services
  Company strategy
Eurofins MWG Operon
  Company overview
  Products and services
  Company strategy
GE Healthcare
  Company overview
  Products and services
  Company strategy
Gen-Probe Life Sciences
  Company overview
  Products and services
  Company strategy
GVK Biosciences (GVK BIO)
  Company overview
  Products and services
  Company strategy
Helicos BioSciences Corp.
  Company overview
  Products and services
  Company strategy
Illumina, Inc
  Company overview
  Products and services
  Company strategy
Integrated DNA Technologies
  Company overview
  Products and services
  Company strategy
Kapa Biosystems, Inc
  Company overview
  Products and services
  Company strategy
Life Technologies Corp.
  Company overview
  Products and services
  Company strategy
Microchip Biotechnologies, Inc
  Company overview
  Products and services
  Company strategy
Nanogen, Inc
  Company overview
  Products and services
  Company strategy
Ocimum Biosolutions Ltd.
  Company overview
  Products and services
  Company strategy
Pacific Biosciences
  Company overview
  Company strategy
PamGene
  Company overview
  Products and services
  Company strategy
Promega Corp.
  Company overview
  Products and services
  Company strategy
QIAGEN
  Company overview
  Products and services
  Company strategy
Sequenom
  Company overview
  Products and services
  Company strategy
Shimadzu Biotech
  Company overview
  Products and services
  Company strategy
Siemens Healthcare Diagnostics
  Company overview
  Products and services
  Company strategy
Sigma-Aldrich
  Company overview
  Products and services
  Company strategy
SoftGenetics, LLC.
  Company overview
  Products and services
  Company strategy
Thermo Fisher Scientific, Inc
  Company overview
  Products and services
  Company strategy
Third Wave Technologies, Inc
  Company overview
  Products and services
  Company strategy
VisiGen Biotechnologies
  Company overview
  Products and services
  Company strategy
ZS Genetics
  Company overview
  Products and services
  Company strategy

CHAPTER 5 APPENDIX

Glossary
Patents

LIST OF FIGURES

Figure 1.1: Developments in DNA sequencing
Figure 1.2: DNA sequencing in drug discovery and development
Figure 1.3: DNA sequencing and drug discovery market
Figure 1.4: Relative importance of features of DNA sequencing tools, 2009 versus 2014
Figure 1.5: DNA sequencing market drivers
Figure 1.6: DNA sequencing tools market dynamics
Figure 1.7: Patent analysis by technology, 2007 versus 2009
Figure 1.8: Patent analysis by geography, 2006 versus 2008
Figure 1.9: Patent applications (%) by competitors, 2004– Oct 09
Figure 2.10: Major segments of the global DNA sequencing market (%), 2008–09
Figure 2.11: Competitive landscape (%), 2008–09

LIST OF TABLES

Table 1.1: Global DNA sequencing market by tools and services ($m), 2007–14
Table 1.2: Global DNA sequencing applications market by applications ($m), 2007–14
Table 1.3: Global drug development market, by applications ($m), 2007–14
Table 1.4: Global drug discovery market, by applications ($m), 2007–14
Table 2.5: Global DNA sequencing market, by geography ($m), 2007–14
Table 2.6: Agreements and collaborations in the DNA sequencing market, 2008–09
Table 2.7: New product, technology & service launch in the DNA sequencing market, 2008–09
Table 2.8: New product, technology & service launch in the DNA sequencing market, 2008–09 (ctd1)
Table 2.9: New product, technology & service launch in the DNA sequencing market, 2008–09 (ctd2)
Table 2.10: New product, technology & service launch in the DNA sequencing market, 2008–09 (ctd3)
Table 3.11: Global DNA sequencing tools market, by geography ($m), 2007–14
Table 3.12: Global DNA sequencing tools market, by products ($m), 2007–14
Table 3.13: Global microarray market, by products ($m), 2007–14
Table 3.14: Global microarray market, by geography ($m), 2007–14
Table 3.15: Global biochip microarray market, by geography ($m), 2007–14
Table 3.16: Global gel array market, by geography ($m), 2007–14
Table 3.17: Global array design kit market, by geography ($m), 2007–14
Table 3.18: Global high and low density microarray market, by geography ($m), 2007–14
Table 3.19: Global bioinformatics market, by products ($m), 2007–14
Table 3.20: Global bioinformatics market, by geography ($m), 2007–14
Table 3.21: Global electrophoresis market, by products ($m), 2007–14
Table 3.22: Global electrophoresis market, by geography ($m), 2007–14
Table 3.23: Global gel electrophoresis market, by geography ($m), 2007–14
Table 3.24: Global capillary electrophoresis market, by geography ($m), 2007–14
Table 3.25: Global DNA sequencing kits and others market, by geography ($m), 2007–14
Table 3.26: Global consumables, chemicals, reagents and probes market, by products ($m), 2007–14
Table 3.27: Global consumables, chemicals, reagents and probes market, by geography ($m), 2007–14
Table 3.28: Global DNA polymerase market, by geography ($m), 2007–14
Table 3.29: Global primers market, by geography ($m), 2007–14
Table 3.30: Global automated DNA sequencers market, by geography ($m), 2007–14
Table 3.31: Global chromatography market, by geography ($m), 2007–14
Table 3.32: Global DNA amplification (PCR) market, by geography ($m), 2007–14
Table 3.33: Global mass spectrometry market, by geography ($m), 2007–14
Table 3.34: Global microscopy-based techniques market, by products ($m), 2007–14
Table 3.35: Global microscopy-based techniques market, by geography, ($m), 2007–14
Table 3.36: Global electron microscopy market, by geography ($m), 2007–14
Table 3.37: Global AFM market, by geography ($m), 2007–14
Table 3.38: Global microfluidics-enabled workstations market, by geography ($m), 2007–14
Table 3.39: Global barcode readers market for DNA sample presentation, by geography ($m), 2007–14
Table 3.40: Global computational chemistry and biology modeling market, by geography ($m), 2007–14
Table 3.41: Global spotters/arrayers market, by geography ($m), 2007–14
Table 3.42: Global centrifuge market, by geography ($m), 2007–14
Table 3.43: Global scanners market, by geography ($m), 2007–14
Table 3.44: Global thermal cycler market, by geography ($m), 2007–14
Table 3.45: Global charge-coupled devices market, by geography ($m), 2007–14
Table 3.46: Global plates, strips and columns market by geography ($m), 2007–14
Table 3.47: Global DNA sequencing services market by products ($m), 2007–14
Table 3.48: Global DNA sequencing services market, by geography ($m), 2007–14
Table 3.49: Global high throughput sequencing market, by geography ($m), 2007–14
Table 3.50: Global shotgun sequencing market, by geography ($m), 2007–14
Table 3.51: Global re-sequencing market, by geography ($m), 2007–14
Table 3.52: Global sample process and primer walking market by geography ($m), 2007–14
Table 3.53: Global single pass analysis market, by geography ($m), 2007–14
Table 3.54: Global bacterial identification market, by geography ($m), 2007–14
Table 5.55: US patents
Table 5.56: US patents (ctd 1)
Table 5.57: US patents (ctd 2)
Table 5.58: US patents (ctd 3)
Table 5.59: US patents (ctd 4)
Table 5.60: US patents (ctd 5)
Table 5.61: US patents (ctd 6)
Table 5.62: US patents (ctd 7)
Table 5.63: US patents (ctd 8)
Table 5.64: European patents
Table 5.65: European patents (ctd 1)
Table 5.66: European patents (ctd 2)
Table 5.67: European patents (ctd 3)
Table 5.68: European patents (ctd 4)
Table 5.69: European patents (ctd 5)
Table 5.70: European patents (ctd 6)
Table 5.71: European patents (ctd 7)
Table 5.72: European patents (ctd 7)
Table 5.73: European patents (ctd 8)
Table 5.74: European patents (ctd 9)
Table 5.75: European patents (ctd 10)
Table 5.76: European patents (ctd 11)
Table 5.77: Japanese patents
Table 5.78: Japanese patents (ctd 2)
Table 5.79: Japanese patents (ctd 3)
Table 5.80: Japanese patents (ctd 4)
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