Developments in Neurostimulation

Date: June 22, 2011
Pages: 75
Price:
US$ 3,835.00
Publisher: Business Insights
Report type: Strategic Report
Delivery: E-mail Delivery (PDF)
ID: D2276FC0BF3EN
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Developments in Neurostimulation
Introduction

The magnitude of research and development executed in neurostimulation innovation is high. Some of the prominent areas in neurostimulation where extensive clinical trails are executed include deep brain stimulation (DBS), spinal cord stimulation (SCS), and microstimulation.

Features and benefits
  • Identify the specific diseases for which neurostimulation has potential applicability.
  • Understand the scientific principles underlying neurostimulation technologies, and how the devices differ between disease areas.
  • Assess the areas in which further research is necessary before neurostimulation devices become widespread clinical tools.
  • Examine the most prominent challenges remaining to be solved and analyze the hurdles that have slowed progress.
  • Gain an overview of key companies in the field and compare their level of research activity and areas of research focus.

Highlights

The microstimulator was proposed to be a single point solution, being capable of treating all neurological pathologies. The Bion microstimulator has shown considerable promise, but since its aquisition by Boston Scientific, progress to the market has slowed dramatically.

Progress in the development of devices for drop foot and grasp is limited by two main challenges. The first is the need for placing electrodes at more than one location, because muscles work in groups. The second is battery life, owing to the high current needed to stimulate the large muscles, and the highly variable patient to patient usage.

Deep brain stimulation has shown promise for the treatment of both depression and obsessive-compulsive disorder, although such use remains at a nascent stage and larger scale trials will be necessary to provide conclusive evidence.

Your key questions answered
  • What are the prominent neurological pathologies that are the subject of research into treatment by the application of neurostimulation devices?
  • How will neurostimulation devices evolve over the next decade?
  • What research challenges prevail in the application of neurostimulation devices?
  • What key neurostimulation patent applications have been published recently?
  • How successful is transcranial magnetic stimulation in treatment of depression?
EXECUTIVE SUMMARY

Neurological pathologies
Neurostimulation devices

ABOUT BUSINESS INSIGHTS

Disclaimer

INTRODUCTION

What is this report about?
Methodology

NEUROLOGICAL PATHOLOGIES

Summary
Introduction
Neuron physiology
Neurological pathologies
Dementia
Non-dementia neurological diseases

NEUROSTIMULATION DEVICES

Summary
Introduction
Electric and magnetic stimulators
Strength and charge duration
Principles of stimulators
  Constant voltage stimulator
  Constant current stimulator
Microstimulators
  Background
  Assessment of the Bion microstimulator
Drop foot and grasp stimulation
  Drop foot stimulation
  Grasp stimulation
  Assessment of stimulators for drop foot and grasp
Cochlear stimulation
  Background
  Assessment of cochlear stimulation
Visual stimulation
  Background
  Assessment of visual stimulation
Spinal cord and bladder stimulation
  Spinal cord stimulation
  Stimulation for bladder dysfunction
  Assessment of spinal cord and bladder stimulation
Deep brain stimulation
  Background
  DBS for depression
  DBS treatment for psychiatric illness – is it ethical?
  Assessment of deep brain stimulation
Magnetic stimulation
  Background
  Transcranial magnetic stimulation
  Magnetic mirror stimulation
  Assessment of magnetic stimulation

PROMINENT COMPANIES IN NEUROSTIMULATION

Medtronic
  Overview
  Business Insights’ pick: key Medtronic neurostimulation patent applications
Boston Scientific
  Overview
  Business Insight’s pick: key Boston Scientific neurostimulation patent applications
St Jude Medical
  Overview
  Business Insight’s pick: key St Jude Medical neurostimulation patent applications
Advanced Bionics
  Overview
  Business Insights’ pick: key Advanced Bionics neurostimulation patent application
Intelect Medical
  Overview
  Business Insights’ pick: key Intelect Medical neurostimulation patent application
Cyberonics
  Overview
  Business Insights’ pick: key Cyberonics neurostimulation patent applications
Neuropace
  Overview
  Business Insights’ pick: key Neuropace neurostimulation patent application
Optobionics
  Overview
BioControl Medical
  Overview
  Business Insights’ pick: key BioControl Medical neurostimulation patent application
Brainsway
  Overview

APPENDIX

Abbreviations
Bibliography
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