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Future Horizons in the UK Cancer Diagnostics Market: Supplier Shares and Sales Forecasts for 40 Tumor Markers by Market Segment

August 2012 | 575 pages | ID: F2CA7552E8EEN
Venture Planning Group

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Highlights
  • Comprehensive 575-page analysis of the UK tumor marker testing market.
  • Major issues pertaining to the UK laboratory practice, as well as key economic, regulatory, demographic, social and technological trends with significant market impact during the next ten years.
  • Mortality statistics and scientific views on the etiology of major types of cancer, e.g., lung, colorectal, breast, prostatic, pancreatic, leukemia, lymphoma, gastrointestinal, bladder, liver, ovarian, testicular, oral, skin and others.
  • Ten-year test volume and sales forecasts over for 40 tumor marker performed in UK hospitals, commercial laboratories and physician offices.
  • Placements and installed base of automated and semi-automated analyzers used for tumor marker testing.
  • Current instrumentation technologies and feature comparison of leading analyzers.
  • Sales and market shares of leading suppliers.
  • Emerging diagnostic technologies and their potential market applications.
  • Product development opportunities.
  • Profiles of current and emerging suppliers, including their sales, market shares, product portfolios, marketing tactics, technological know-how, new products in R&D, collaborative arrangements and business strategies.
  • Business opportunities and strategic recommendations for suppliers.
Contains 575 pages and 85 tables
INTRODUCTION

WORLDWIDE MARKET AND TECHNOLOGY OVERVIEW

A. CANCER STATISTICS AND ETIOLOGY


1. Brest Cancer
2. Lung Cancer
3. Colon and Rectum Cancer
4. Prostate Cancer
5. Stomach Cancer
6. Leukemia
7. Lymphoma
8. Oral Cancer
9. Skin Cancer
10. Uterine Cancer
11. Ovarian Cancer
12. Bladder Cancer

B. MAJOR CURRENT AND EMERGING CANCER DIAGNOSTIC TESTS

1. Introduction
2. Tumor Marker Classification
3. ACTH
4. Alpha-Fetoprotein (AFP)
5. Beta-2 Microglobulin
6. CA 15-3/27.29
7. CA 19-9
8. CA-125
9. Calcitonin
10. Carcinoembrionic Antigen (CEA)
11. Estrogen and Progesterone Receptors
12. Ferritin
13. Gastrin
14. Human Chorionic Gonadotropin (HCG)
15. Insulin
16. NSE
17. Occult Blood
18. PAP Smear/HPV
19. Prostatic Acid Phosphatase (PAP)
20. Prostate-Specific Antigen (PSA)
21. Squamous Cell Carcinoma Antigen (SCC)
22. T and B Lymphocytes
23. TdT
24. Thyroglobulin
25. Tissue Polypeptide Antigen (TPA)
26. Biochemical Tumor Markers
  ADA
  B-Protein
  PNP
  5'-Nucleotidase
27. Oncogenes
  Abl/abl-bcr
  AIB1
  BCL-2
  BRCA1
  CD44
  C-fos
  C-myb
  C-myc
  CYP-17
  Erb-B
  HPC1
  N-myc
  P40
  P51
  P53
  PIK3CA
  PTI-1
  Ras
  Reg
  Sis
  Src
28. Polypeptide Growth Factors
  Basic Fibroblast Growth Factor -Beta-TGF
  Cachectin (TNT)
  Calmodulin
  ECFR
  Nerve Growth Factor (NGF)
  Epidermal Growth Factor (EGF)
  Ornithine Decarboxylase
  Transferrin
  Transforming Growth Factor-Alpha
29. Ectopic Hormones
30. Colony Stimulating Factors
31. Lymphokines
  Alpha-Interferon
  B Cell Growth Factors
  B Cell Growth Factor (BCGF)
  Gamma-Interferon
  Interleukin-1 (IL-1)
  Macrophage Activating Factor 32. Immunohistochemical Stains
33. Emerging Tumor Markers
  N-Acetylglucosamine
  Actin
  Alpha-Actin
  Antineuronal Antibodies
  7B2
  B72.3
  Bax
  BCD-F9
  BLCA-4
  Blood Group Antigens A,B,H
  CA 50
  CA 72-4/TAG-72
  CA 195
  CA-242
  CA-549
  CAM 26
  CAR-3
  Cathepsin-D
  Chromogranin A and B
  Cluster 1 Antigen
  Cluster-5/5A Antigen
  CTA
  CU18
  DR-70
  DU-PAN-2
  Endometrial Bleeding Associated Factor-Endostatin
  Epithelial Membrane Antigen
  Feulgen Hydrolysis
  Fibronectin
  FSH
  (1->3)-L-fucosyltransferase
  Gastrin-Releasing Peptide (GRP)
  GDCFP-15
  Glucagon
  Glycoamines
  H23
  Her-2
  Human Carcinoma Antigen
  HPA
  HSP27
  Intermediate Filaments
  Cytokeratins/CK18/Cyfra 21-1
  Desmin
  Gliofibrillary Acid Protein
  Neurofilaments
  Vimentin
  KA 93
  Kinases
  KP16D3
  LAI
  Leukocyte Common Antigen
  Lewis Antigens
  Lysophosphatidic Acid (LPA)
  Ma 695/Ma 552
  MABDF3
  MAG
  ME1
  Minactivin
  MN/CA9
  MSA
  Mucin Cancer Antigen (MCA)
  Multiple Tumor Suppressor 1
  Myosin
  NEA-130
  NMP22
  OA-519
  Opiod Peptides
  P-glycoprotein
  Pancreatic Oncofetal Antigen (POA)
  Placental Lactogen
  PR92
  Proliferative Index, Ki-67
  Px
  RB Inactivation/Deletion
  Ret
  SCCL 175
  Selectin
  Sialic Acid
  Sialyl SSEA-1/SLX
  SN10
  Somatostatin
  TA-90
  TABA
  Tachykinin
  TAG 12
  TPS
  Troponin
  Tubulin
  VCAM
  VEGF
  Villen

C. INSTRUMENTATION REVIEW AND MARKET NEEDS

1. Abbott AxSYM
2. Abbott Architect c4000
3. Abbott Architect i2000 Series
4. Abbott Architect ci8200 System
5. Beckman Coulter UniCel Series
6. Beckman Coulter Access
7. Binding Site ESP600
8. bioMerieux Mini Vidas
9. Carolina Chemistries BioLis 24i
10. DiaSorin Liaison
11. Horiba ABX Pentra 400
12. Inverness DS2
13. J&J Vitros ECi/ECiQ
14. J&J Vitros 3600
15. J&J Vitros 5600
16. Olympus AU5400
17. Olympus AU3000i
18. Olympus AU2700
19. Roche Modular Analytics
20. Roche Cobas Integra 400
21. Roche Cobas Integra 400 Plus
22. Roche Elecsys
23. Roche Cobas c311
24. Siemens ADVIA Centaur
25. Siemens Dimension
26. Siemens Dimension RxL Max
27. Siemens Dimension Vista 500
28. Siemens Immulite
29. Siemens Stratus
30. Tosoh AIA-Series
31. Vital Diagnostics ATAC 8000
32. Vital Diagnostics Envoy 500

D. CURRENT AND EMERGING TECHNOLOGIES

1. Monoclonal and Polyclonal Antibodies
2. Immunoassays
  a. Technological Principle
  b. Radioimmunoassay (RIA)
  c. Enzyme Immunoassays (EIA)
    Overview
    ELISA
    Immunofiltration
    Particle-Membrane Capture Immunoassay
    Enzyme Amplification
  d. Fluorescent Immunoassays
  e. Luminescence
    Chemiluminescence
    Bioluminescence
  f. Latex Agglutination
  g. Immunoprecipitation
  h. Affinity Chromatographu
  e. Liposome Flow-Injection Immunoassay
3. Molecular Diagnostics
  a. Technology Overview
  b. Amplification Methods
    PCR
    DAP-PCR
    Immuno-PCR
    QC-PCR
    CAR
    DNA
    HPA
    LCR
    NASBA
    QBR
    SDA
    3 SR, and others
4. Chromosome Analysis
  a. Chronic Myelogenous Leukemia (CML)
  b. Acute Myeloid Leukemia (AML)
  c. Acute Lymphoblastic Leukemia (ALL)
  d. Malignant Lymphomas Lymphoid Malignancies
  e. Chronic Lymphocytic Leukemia (CLL)
  f. Solid Cancers
  g. Chromosomal Translocation and Oncogenes
5. Artificial Intelligence
6. Flow Cytometry
7. Two Dimensional Gel Electrophoresis (2-DGE)
8. Biosensors
9. Competing/Complementing Technologies
  a. CT
  b. MRI
  c. NMR
  d. PET
  e. Photonics Spectroscopy

E. PERSONAL TESTING

U.K.

A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Growth and Major Suppliers

MAJOR PRODUCT DEVELOPMENT OPPORTUNITIES

A. Reagent Kits and Test Systems/Panels
B. Instrumentation
C. Computers, Software and Automation
D. Auxiliary Products

DESIGN CRITERIA FOR DECENTRALIZED TESTING PRODUCTS

ALTERNATIVE MARKET PENETRATION STRATEGIES


A. Internal Development
B. Collaborative Arrangements
C. University Contracts
D. Distribution Strategies
  1. Marketing Approaches
  2. Product Complexity
  3. Customer Preference
  4. Established Suppliers
  5. Emerging Suppliers
  6. Major Types of Distributors
  7. Market Segmentation Factor

POTENTIAL MARKET ENTRY BARRIERS AND RISKS

A. Market Maturity
B. Cost Containment
C. Competition
D. Technological Edge and Limitations
E. Patent Protection
F. Regulatory Constraints
G. Decentralized Testing Market Challenges

COMPETITIVE PROFILES

  Abbott
  AdnaGen
  Applied Gene Technologies
  Arca
  Beckman Coulter/Danaher
  Becton Dickinson
  Biomedical Diagnostics
  bioMerieux
  Bio-Rad
  Cepheid
  Correlogic Systems
  Dako
  Decode
  Diadexus
  Diagnocure
  Diasorin
  Eiken Chemical
  Enterix
  Enzo Biochem
  Epigenomics
  Exact Sciences
  Fujirebio
  Gen-Probe
  Guided Therapeutics
  Hologic
  Ipsogen
  Kreatech
  Kyowa Medex
  Life Technologies
  Mackay Life Sciences
  Myriad Genetics
  Nanogen Elitech
  OncoLab
  Otho-Clinical Diagnostics
  Panacea Pharmaceuticals
  Polartechnics
  Polymedco
  PreMD
  Qiagen
  Radient Pharmaceuticals
  Roche
  Scienion
  Sequenom
  Siemens Healthcare
  Takara Bio
  Targeted Diagnostics & Therapeutics
  Tosoh
  Veridex
  Wako Pure Chemicals
  Wallac/PE
  Zila

APPENDIXES

Appendix I: Major Universities and Research Centers Developing Cancer Diagnostic Technology and Applications
Appendix II: Assumed Currency Exchange Rates

LIST OF TABLES

Tumor Marker Classification
Major Companies Developing or Marketing ACTH Tests
Major Companies Developing or Marketing AFP Tests
Major Companies Developing or Marketing Beta-2 Microglobulin Tests
Major Companies Developing or Marketing CA 15-3/27.29 Tests
Major Companies Developing or Marketing CA 19-9 Tests
Major Companies Developing or Marketing CA 125 Tests
Major Companies Developing or Marketing Calcitonin Tests
Major Companies Developing or Marketing CEA Tests
Major Companies Developing or Marketing Estrogen Receptor Tests
Major Companies Developing or Marketing Progesterone Receptor Tests
Major Companies Developing or Marketing Ferritin Tests
Major Companies Developing or Marketing Gastrin Tests
Major Companies Developing or Marketing HCG Tests
Major Companies Developing or Marketing Insulin Tests
Major Companies Developing or Marketing NSE Tests
Major Companies Developing or Marketing Occult Blood Tests
Major Companies Developing or Marketing PAP Smear/HPV Tests
Major Companies Developing or Marketing PAP Tests
Major Companies Developing or Marketing PSA Tests
Major Companies Developing or Marketing Lymphocyte Subclassification Tests
Biochemical Markers Potential Applications In Cancer Diagnosis
Oncogenes Potential Applications In Cancer Diagnosis
Major Companies Developing or Marketing Oncogene Tests
Growth Factors Potential Applications In Cancer Diagnosis
Colony Stimulating Factors Potential Applications in Cancer Diagnosis
Lymphokines Potential Applications In Cancer Diagnosis
Immunohistochemical Stains Potential Applications in Cancer Diagnosis
Executive Summary Table: U.K., Total Tumor Marker Test Volume and Sales Forecast by Market Segment
U.K., Estimated Cancer Death Rates Per 100,000 Population
U.K., Laboratories Performing Tumor Marker Tests by Market Segment
U.K., Hospital Laboratories Performing Tumor Marker Tests by Bed Size
U.K., Commercial/Private Laboratories Performing Tumor Marker Tests by Annual Test Volume
U.K., Total Tumor Marker Testing Volume Forecast by Market Segment
U.K., All Market Segments Major Tumor Marker Test Volume Forecast
U.K., Hospital Laboratories Major Tumor Marker Test Volume Forecast by Test
U.K., Commercial/Private Laboratories Major Tumor Marker Test Volume Forecast
U.K., Total Tumor Marker Sales Forecast by Market Segment
U.K., All Market Segments Major Tumor Marker Sales Forecast by Test
U.K., Hospital Laboratories Major Tumor Marker Sales Forecast by Test
U.K., Commercial/Private Laboratories Major Tumor Marker Sales Forecast by Test
U.K., ACTH Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., AFP Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., Beta-2 Microglobulin Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., CA 15-3/27.29 Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., CA 19-9 Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., CA-125 Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., Calcitonin Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., CEA Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., Chromogranin Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., Colon-Specific Antigen Test Volume And Diagnostics Sales by Market Segment
U.K., Cytokeratins Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., Estrogen Receptor Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., Ferritin Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., Gastrin Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., HCG Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., Insulin Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., Lymphocyte Subtyping Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., NSE Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., Occult Blood Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., Oncogenes Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., Pancreatic Oncofetal Antigen Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., PAP Smear Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., Parathyroid Hormone Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., Progesterone Receptor Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., PAP Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., PSA Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., S-100 Protein Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., Serotonin Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., Sialic Acid Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., Squamous Cell Carcinoma Antigen Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., TDT Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., Thymidine Kinase Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., Thyroglobulin Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., TPA Test Volume and Diagnostics Sales Forecast by Market Segment
U.K., Total Tumor Marker Sales and Market Shares Forecast
U.K., CEA Testing Market Diagnostics Sales by Major Supplier
U.K., PSA Testing Market Diagnostics Sales by Major Supplier


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